4X9PA

Crystal structure of bovine annexin a2
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
318
structure length
314
Chain Sequence
SAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIVSDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKKKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects.
pubmed doi rcsb
molecule tags Calcium binding protein
source organism Bos taurus
molecule keywords Annexin A2
total genus 128
structure length 314
sequence length 318
ec nomenclature
pdb deposition date 2014-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4x9pA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4x9pA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4x9pA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4x9pA03
1BC3A 1A8AA 1MCXA 1I4AA 1BCZA 1HM6A 1HVFA 1W7BA 1W45A 2XO2A 1YJ0A 1HVEA 2ZHIA 2ZHJA 4HREA 1BC0A 1ALAA 2H0LA 2H0MA 1AVRA 1ANWA 2RANA 1XJLA 4EVFA 1AIIA 1AVHA 1AOWA 2IE6A 2II2A 1BO9A 4MDUA 1HVDA 2HYVA 4X9PA 1ANNA 2HYWA 4MDVA 1N41A 1HAKA 1A8BA 1AVCA 1M9IA 1YIIA 1DK5A 2IICA 1N44A 2XO3A 4EVHA 1BC1A 1N42A 2IE7A 1ANXA 2HYUA 1HVGA 1W3WA 1YCNA 1BCYA 1DM5A 1N00A 2Q4CA 1AXNA 1G5NA 2ZOCA 2H0KA 3BRXA 1SAVA 1BCWA 1AEIA
chains in the Genus database with same CATH superfamily
1UPTB 1I4AA 2ZHIA 3ABRA 2XO2A 1YJ0A 4D7QA 1C1KA 1ALAA 2H0LA 2H0MA 1AVRA 1XJLA 1AIIA 4KN7X 2VXGA 4X9PA 4MDVA 1N41A 4JXHA 1AVCA 1YGMA 1YIIA 4FHRB 3USYA 1BC9A 2XO3A 1N42A 4KN4X 2K6XA 2OY9A 1R8SE 4L5MA 2Q4CA 1W7BA 1S9DE 1R4AE 3USWA 4JK1X 3AJCA 2RANA 4EVFA 1AOWA 4OIYA 4C0AA 1BO9A 4MDUA 1KU1A 2HYVA 1ANNA 2HYWA 1A8BA 1DK5A 1LKVX 1ANXA 3ABSA 1BCYA 4C7PA 1DM5A 1N00A 1G5NA 3BRXA 2H0KA 3ANYA 1MCXA 1BCZA 1HVFA 1W45A 3SOHB 1HVEA 2ZHJA 3HJLA 4HREA 1QC7A 2IE6A 4JMOA 2II2A 4KMUX 1HVDA 4JWLA 2R0DA 1HAKA 1M9IA 2IICA 1Q8DA 4EVHA 3AO0A 1R8ME 4JMIA 1HVGA 1W3WA 1YCNA 1XSZA 1RE0B 1XT0B 1A8AA 1BC3A 3LTLA 1HM6A 1R8QE 1BC0A 3ABOA 1ANWA 2HSNA 1AVHA 4A4PA 3ABQA 1PBVA 4Z21A 2R09A 4Q2SA 4FQ0C 2QEZA 3TW5A 1N44A 1BC1A 2IE7A 2HYUA 4D7RA 1AXNA 2ZOCA 3L8NA 3SWVA 1SAVA 1BCWA 1AEIA
chains in the Genus database with same CATH topology
1BC3A 1A8AA 1MCXA 1I4AA 1BCZA 1HM6A 1HVFA 1W7BA 1W45A 2XO2A 1YJ0A 1HVEA 2ZHIA 2ZHJA 4HREA 1BC0A 1ALAA 2H0LA 2H0MA 1AVRA 1ANWA 2RANA 1XJLA 4EVFA 1AIIA 1AVHA 1AOWA 2IE6A 2II2A 1BO9A 4MDUA 1HVDA 2HYVA 4X9PA 1ANNA 2HYWA 4MDVA 1N41A 1HAKA 1A8BA 1AVCA 1M9IA 1YIIA 1DK5A 2IICA 1N44A 2XO3A 4EVHA 1BC1A 1N42A 2IE7A 1ANXA 2HYUA 1HVGA 1W3WA 1YCNA 1BCYA 1DM5A 1N00A 2Q4CA 1AXNA 1G5NA 2ZOCA 2H0KA 3BRXA 1SAVA 1BCWA 1AEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BC3 A;  1A8A A;  1MCX A;  1I4A A;  1BCZ A;  1HM6 A;  1HVF A;  1W7B A;  1W45 A;  2XO2 A;  1YJ0 A;  1HVE A;  2ZHI A;  2ZHJ A;  4HRE A;  1BC0 A;  1ALA A;  2H0L A;  2H0M A;  1AVR A;  1ANW A;  2RAN A;  1XJL A;  4EVF A;  1AII A;  1AVH A;  1AOW A;  2IE6 A;  2II2 A;  1BO9 A;  4MDU A;  1HVD A;  2HYV A;  4X9P A;  1ANN A;  2HYW A;  4MDV A;  1N41 A;  1HAK A;  1A8B A;  1AVC A;  1M9I A;  1YII A;  1DK5 A;  2IIC A;  1N44 A;  2XO3 A;  4EVH A;  1BC1 A;  1N42 A;  2IE7 A;  1ANX A;  2HYU A;  1HVG A;  1W3W A;  1YCN A;  1BCY A;  1DM5 A;  1N00 A;  2Q4C A;  1AXN A;  1G5N A;  2ZOC A;  2H0K A;  3BRX A;  1SAV A;  1BCW A;  1AEI A; 
#chains in the Genus database with same CATH topology
 1UPT B;  1I4A A;  2ZHI A;  3ABR A;  2XO2 A;  1YJ0 A;  4D7Q A;  1C1K A;  1ALA A;  2H0L A;  2H0M A;  1AVR A;  1XJL A;  1AII A;  4KN7 X;  2VXG A;  4X9P A;  4MDV A;  1N41 A;  4JXH A;  1AVC A;  1YGM A;  1YII A;  4FHR B;  3USY A;  1BC9 A;  2XO3 A;  1N42 A;  4KN4 X;  2K6X A;  2OY9 A;  1R8S E;  4L5M A;  2Q4C A;  1W7B A;  1S9D E;  1R4A E;  3USW A;  4JK1 X;  3AJC A;  2RAN A;  4EVF A;  1AOW A;  4OIY A;  4C0A A;  1BO9 A;  4MDU A;  1KU1 A;  2HYV A;  1ANN A;  2HYW A;  1A8B A;  1DK5 A;  1LKV X;  1ANX A;  3ABS A;  1BCY A;  4C7P A;  1DM5 A;  1N00 A;  1G5N A;  3BRX A;  2H0K A;  3ANY A;  1MCX A;  1BCZ A;  1HVF A;  1W45 A;  3SOH B;  1HVE A;  2ZHJ A;  3HJL A;  4HRE A;  1QC7 A;  2IE6 A;  4JMO A;  2II2 A;  4KMU X;  1HVD A;  4JWL A;  2R0D A;  1HAK A;  1M9I A;  2IIC A;  1Q8D A;  4EVH A;  3AO0 A;  1R8M E;  4JMI A;  1HVG A;  1W3W A;  1YCN A;  1XSZ A;  1RE0 B;  1XT0 B;  1A8A A;  1BC3 A;  3LTL A;  1HM6 A;  1R8Q E;  1BC0 A;  3ABO A;  1ANW A;  2HSN A;  1AVH A;  4A4P A;  3ABQ A;  1PBV A;  4Z21 A;  2R09 A;  4Q2S A;  4FQ0 C;  2QEZ A;  3TW5 A;  1N44 A;  1BC1 A;  2IE7 A;  2HYU A;  4D7R A;  1AXN A;  2ZOC A;  3L8N A;  3SWV A;  1SAV A;  1BCW A;  1AEI A; 
#chains in the Genus database with same CATH homology
 1BC3 A;  1A8A A;  1MCX A;  1I4A A;  1BCZ A;  1HM6 A;  1HVF A;  1W7B A;  1W45 A;  2XO2 A;  1YJ0 A;  1HVE A;  2ZHI A;  2ZHJ A;  4HRE A;  1BC0 A;  1ALA A;  2H0L A;  2H0M A;  1AVR A;  1ANW A;  2RAN A;  1XJL A;  4EVF A;  1AII A;  1AVH A;  1AOW A;  2IE6 A;  2II2 A;  1BO9 A;  4MDU A;  1HVD A;  2HYV A;  4X9P A;  1ANN A;  2HYW A;  4MDV A;  1N41 A;  1HAK A;  1A8B A;  1AVC A;  1M9I A;  1YII A;  1DK5 A;  2IIC A;  1N44 A;  2XO3 A;  4EVH A;  1BC1 A;  1N42 A;  2IE7 A;  1ANX A;  2HYU A;  1HVG A;  1W3W A;  1YCN A;  1BCY A;  1DM5 A;  1N00 A;  2Q4C A;  1AXN A;  1G5N A;  2ZOC A;  2H0K A;  3BRX A;  1SAV A;  1BCW A;  1AEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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