4Z21A

Crystal structure of arno sec7
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
196
structure length
196
Chain Sequence
ANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Lack of evidence that CYTH2/ARNO functions as an intracellular EGFR activator
rcsb
molecule keywords Cytohesin-2
total genus 71
structure length 196
sequence length 196
ec nomenclature
pdb deposition date 2015-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 4z21A01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 4z21A02
1BC9A 1RE0B 3L8NA 1R8QE 4C7PA 4OIYA 3SWVA 4JMIA 4C0AA 1R8SE 4D7QA 1XSZA 4D7RA 1R8ME 4Z21A 4JMOA 4JWLA 4L5MA 3LTLA 1KU1A 4A4PA 4JXHA 1S9DE 1XT0B 2R0DA 1PBVA 2R09A
chains in the Genus database with same CATH superfamily
1BC9A 1RE0B 2XO3A 2H0MA 3ABOA 3SOHB 3AJCA 1W7BA 1XSZA 1DK5A 3USYA 1AEIA 4JWLA 4L5MA 3ABQA 2OY9A 4A4PA 3AO0A 4JXHA 4KMUX 1Q8DA 3ANYA 2RANA 2IE7A 2R09A 3ABRA 1R8QE 2IE6A 1BC0A 2HYWA 3SWVA 1LKVX 1N44A 1A8AA 1A8BA 4D7QA 2IICA 1ANXA 4D7RA 4Z21A 4JMOA 2VXGA 1BO9A 4MDVA 1N42A 2ZOCA 4EVFA 1AVCA 2HSNA 2QEZA 1ALAA 1BCZA 1C1KA 4EVHA 4X9PA 1QC7A 1YJ0A 2HYUA 2XO2A 3L8NA 1AVHA 2II2A 3BRXA 1HVDA 4C7PA 1BCWA 2ZHIA 1HVEA 1R4AE 2K6XA 2H0KA 1DM5A 4FQ0C 2ZHJA 4HREA 3LTLA 1AIIA 4MDUA 1ANNA 4FHRB 3USWA 1UPTB 1HAKA 2R0DA 1PBVA 1N41A 1AOWA 4JK1X 1XJLA 1YCNA 1G5NA 1HVFA 2HYVA 1N00A 1HM6A 4Q2SA 1AXNA 2H0LA 4OIYA 1SAVA 4JMIA 1I4AA 4C0AA 1R8SE 1ANWA 1M9IA 1W3WA 1YIIA 1R8ME 3HJLA 1BC1A 1HVGA 1W45A 4KN4X 1BCYA 3TW5A 1MCXA 1BC3A 1KU1A 3ABSA 2Q4CA 1S9DE 1XT0B 1YGMA 4KN7X 1AVRA
chains in the Genus database with same CATH topology
1BC9A 1RE0B 3L8NA 1R8QE 4C7PA 4OIYA 3SWVA 4JMIA 4C0AA 1LKVX 3SOHB 1R8SE 3AJCA 4D7QA 1XSZA 2K6XA 4D7RA 1R8ME 3HJLA 4Z21A 4JMOA 4FQ0C 3USYA 4JWLA 4L5MA 3LTLA 4KN4X 3TW5A 1KU1A 2HSNA 4FHRB 3USWA 4A4PA 4JXHA 4KMUX 1S9DE 1Q8DA 1XT0B 4KN7X 2R0DA 1QC7A 1PBVA 4JK1X 2R09A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BC9 A;  1RE0 B;  3L8N A;  1R8Q E;  4C7P A;  4OIY A;  3SWV A;  4JMI A;  4C0A A;  1R8S E;  4D7Q A;  1XSZ A;  4D7R A;  1R8M E;  4Z21 A;  4JMO A;  4JWL A;  4L5M A;  3LTL A;  1KU1 A;  4A4P A;  4JXH A;  1S9D E;  1XT0 B;  2R0D A;  1PBV A;  2R09 A; 
#chains in the Genus database with same CATH topology
 1BC9 A;  1RE0 B;  2XO3 A;  2H0M A;  3ABO A;  3SOH B;  3AJC A;  1W7B A;  1XSZ A;  1DK5 A;  3USY A;  1AEI A;  4JWL A;  4L5M A;  3ABQ A;  2OY9 A;  4A4P A;  3AO0 A;  4JXH A;  4KMU X;  1Q8D A;  3ANY A;  2RAN A;  2IE7 A;  2R09 A;  3ABR A;  1R8Q E;  2IE6 A;  1BC0 A;  2HYW A;  3SWV A;  1LKV X;  1N44 A;  1A8A A;  1A8B A;  4D7Q A;  2IIC A;  1ANX A;  4D7R A;  4Z21 A;  4JMO A;  2VXG A;  1BO9 A;  4MDV A;  1N42 A;  2ZOC A;  4EVF A;  1AVC A;  2HSN A;  2QEZ A;  1ALA A;  1BCZ A;  1C1K A;  4EVH A;  4X9P A;  1QC7 A;  1YJ0 A;  2HYU A;  2XO2 A;  3L8N A;  1AVH A;  2II2 A;  3BRX A;  1HVD A;  4C7P A;  1BCW A;  2ZHI A;  1HVE A;  1R4A E;  2K6X A;  2H0K A;  1DM5 A;  4FQ0 C;  2ZHJ A;  4HRE A;  3LTL A;  1AII A;  4MDU A;  1ANN A;  4FHR B;  3USW A;  1UPT B;  1HAK A;  2R0D A;  1PBV A;  1N41 A;  1AOW A;  4JK1 X;  1XJL A;  1YCN A;  1G5N A;  1HVF A;  2HYV A;  1N00 A;  1HM6 A;  4Q2S A;  1AXN A;  2H0L A;  4OIY A;  1SAV A;  4JMI A;  1I4A A;  4C0A A;  1R8S E;  1ANW A;  1M9I A;  1W3W A;  1YII A;  1R8M E;  3HJL A;  1BC1 A;  1HVG A;  1W45 A;  4KN4 X;  1BCY A;  3TW5 A;  1MCX A;  1BC3 A;  1KU1 A;  3ABS A;  2Q4C A;  1S9D E;  1XT0 B;  1YGM A;  4KN7 X;  1AVR A; 
#chains in the Genus database with same CATH homology
 1BC9 A;  1RE0 B;  3L8N A;  1R8Q E;  4C7P A;  4OIY A;  3SWV A;  4JMI A;  4C0A A;  1LKV X;  3SOH B;  1R8S E;  3AJC A;  4D7Q A;  1XSZ A;  2K6X A;  4D7R A;  1R8M E;  3HJL A;  4Z21 A;  4JMO A;  4FQ0 C;  3USY A;  4JWL A;  4L5M A;  3LTL A;  4KN4 X;  3TW5 A;  1KU1 A;  2HSN A;  4FHR B;  3USW A;  4A4P A;  4JXH A;  4KMU X;  1S9D E;  1Q8D A;  1XT0 B;  4KN7 X;  2R0D A;  1QC7 A;  1PBV A;  4JK1 X;  2R09 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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