2N19A

Stil binding to the polo-box domain 3 of plk4 regulates centriole duplication
Total Genus 18
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
88
structure length
88
Chain Sequence
GSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title STIL binding to Polo-box 3 of PLK4 regulates centriole duplication.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Serine/threonine-protein kinase PLK4
total genus 18
structure length 88
sequence length 88
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2015-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 2n19A00
4YYPA 4HY2A 5DNJA 3FVHA 4E9CA 4LKMA 4LKLA 5J19A 4RS6A 3P34A 4XB0A 4O9WA 5LHZA 2N19A 1Q4OA 3P2ZA 4DFWA 3P36A 4HABA 4X9WA 3C5LA 3P35A 4WHLA 1Q4KA 5DMVC 5DMSA 4E9DA 4X9VA 2OJXA 4O6WA 4X9RA 3BZIA 4H5XA 3RQ7A 3HIKA 3Q1IA 4HCOA 4J7BB 3P2WA 1UMWA 4WHHA 3P37A 2OGQA 4E67A 4WHKA 4H71A 4O56A 3HIHA 4RCPA
chains in the Genus database with same CATH superfamily
4YYPA 4HY2A 5DNJA 4LKLA 5AJ9A 5LHZA 2N19A 1A87A 2E50A 4CXSA 1P49A 4FDJA 2I9ZA 2IA9A 3HIKA 4NK7A 3P2WA 1UMWA 4WHHA 4E67A 4RCPA 4LKMA 4RS6A 1AUKA 4DFWA 4X9WA 3P35A 1Q4KA 5DMVC 4CYRA 4E9DA 1FSUA 4X9VA 5DAYA 4N7ZA 1E3CP 1E1ZP 4NKBA 3GYVA 4O56A 4X9RA 2VKZG 3KDRA 4O9WA 1Q4OA 4G7NA 3GYWA 1E2TA 2I9XA 4HABA 4WHLA 4CXKA 3LM3A 4O6WA 3BZIA 4N7VA 4H5XA 3RQ7A 3Q1IA 4HCOA 4J7BB 3P37A 3FS3A 1F32A 4WHKA 5DMSA 1F34B 3FVHA 4E9CA 3LXQA 4FDIA 5J19A 4N9JA 2QZUA 3P34A 4XB0A 4CYSA 3P2ZA 3P36A 2UV8G 3C5LA 1E33P 3ED4A 1E2SP 2OJXA 3HMJG 1HDHA 3HFDA 1N2KA 2OGQA 4H71A 1N2LA 3HIHA 4CXUA
chains in the Genus database with same CATH topology
4YYPA 4HY2A 5DNJA 3FVHA 4E9CA 4LKMA 4LKLA 5J19A 4RS6A 3P34A 4XB0A 4O9WA 5LHZA 2N19A 1Q4OA 3P2ZA 4DFWA 3P36A 4HABA 4X9WA 3C5LA 3P35A 4WHLA 1Q4KA 5DMVC 5DMSA 4E9DA 4X9VA 2OJXA 4O6WA 4X9RA 3BZIA 4H5XA 3RQ7A 3HIKA 3Q1IA 4HCOA 4J7BB 3P2WA 1UMWA 4WHHA 3P37A 2OGQA 4E67A 4WHKA 4H71A 4O56A 3HIHA 4RCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YYP A;  4HY2 A;  5DNJ A;  3FVH A;  4E9C A;  4LKM A;  4LKL A;  5J19 A;  4RS6 A;  3P34 A;  4XB0 A;  4O9W A;  5LHZ A;  2N19 A;  1Q4O A;  3P2Z A;  4DFW A;  3P36 A;  4HAB A;  4X9W A;  3C5L A;  3P35 A;  4WHL A;  1Q4K A;  5DMV C;  5DMS A;  4E9D A;  4X9V A;  2OJX A;  4O6W A;  4X9R A;  3BZI A;  4H5X A;  3RQ7 A;  3HIK A;  3Q1I A;  4HCO A;  4J7B B;  3P2W A;  1UMW A;  4WHH A;  3P37 A;  2OGQ A;  4E67 A;  4WHK A;  4H71 A;  4O56 A;  3HIH A;  4RCP A; 
#chains in the Genus database with same CATH topology
 4YYP A;  4HY2 A;  5DNJ A;  4LKL A;  5AJ9 A;  5LHZ A;  2N19 A;  1A87 A;  2E50 A;  4CXS A;  1P49 A;  4FDJ A;  2I9Z A;  2IA9 A;  3HIK A;  4NK7 A;  3P2W A;  1UMW A;  4WHH A;  4E67 A;  4RCP A;  4LKM A;  4RS6 A;  1AUK A;  4DFW A;  4X9W A;  3P35 A;  1Q4K A;  5DMV C;  4CYR A;  4E9D A;  1FSU A;  4X9V A;  5DAY A;  4N7Z A;  1E3C P;  1E1Z P;  4NKB A;  3GYV A;  4O56 A;  4X9R A;  2VKZ G;  3KDR A;  4O9W A;  1Q4O A;  4G7N A;  3GYW A;  1E2T A;  2I9X A;  4HAB A;  4WHL A;  4CXK A;  3LM3 A;  4O6W A;  3BZI A;  4N7V A;  4H5X A;  3RQ7 A;  3Q1I A;  4HCO A;  4J7B B;  3P37 A;  3FS3 A;  1F32 A;  4WHK A;  5DMS A;  1F34 B;  3FVH A;  4E9C A;  3LXQ A;  4FDI A;  5J19 A;  4N9J A;  2QZU A;  3P34 A;  4XB0 A;  4CYS A;  3P2Z A;  3P36 A;  2UV8 G;  3C5L A;  1E33 P;  3ED4 A;  1E2S P;  2OJX A;  3HMJ G;  1HDH A;  3HFD A;  1N2K A;  2OGQ A;  4H71 A;  1N2L A;  3HIH A;  4CXU A; 
#chains in the Genus database with same CATH homology
 4YYP A;  4HY2 A;  5DNJ A;  3FVH A;  4E9C A;  4LKM A;  4LKL A;  5J19 A;  4RS6 A;  3P34 A;  4XB0 A;  4O9W A;  5LHZ A;  2N19 A;  1Q4O A;  3P2Z A;  4DFW A;  3P36 A;  4HAB A;  4X9W A;  3C5L A;  3P35 A;  4WHL A;  1Q4K A;  5DMV C;  5DMS A;  4E9D A;  4X9V A;  2OJX A;  4O6W A;  4X9R A;  3BZI A;  4H5X A;  3RQ7 A;  3HIK A;  3Q1I A;  4HCO A;  4J7B B;  3P2W A;  1UMW A;  4WHH A;  3P37 A;  2OGQ A;  4E67 A;  4WHK A;  4H71 A;  4O56 A;  3HIH A;  4RCP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...