3HIHA

Structure of human plk1-pbd with glycerol and sulfate in the phophopeptide binding site
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
223
structure length
223
Chain Sequence
b'DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 74
structure length 223
sequence length 223
chains with identical sequence B
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2009-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3hihA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3hihA01
4X9VA 3Q1IA 4O56A 2OJXA 3HIKA 4LKMA 3FVHA 4H71A 3P35A 4WHHA 4X9WA 4O9WA 5DMVC 3P2ZA 4WHKA 5LHZA 4LKLA 2N19A 3HIHA 4O6WA 3P34A 2OGQA 4H5XA 4E67A 4X9RA 4DFWA 4E9DA 1Q4KA 4WHLA 4J7BB 1UMWA 4XB0A 4HABA 3P2WA 4HCOA 5DMSA 4E9CA 5J19A 3C5LA 3P37A 4RCPA 4RS6A 4YYPA 4HY2A 1Q4OA 3P36A 3RQ7A 5DNJA 3BZIA
chains in the Genus database with same CATH superfamily
4X9VA 4LKMA 1E33P 4CXKA 5DAYA 5DMVC 3HMJG 4O6WA 2OGQA 2QZUA 1Q4KA 4N9JA 1P49A 1N2LA 3ED4A 3P2WA 4XB0A 4CYRA 4FDIA 2VKZG 4RCPA 1Q4OA 3FS3A 1F32A 2OJXA 4CYSA 4O9WA 1N2KA 3P2ZA 4WHKA 5LHZA 4G7NA 3P34A 3GYWA 4WHLA 1HDHA 1UMWA 4HABA 4HCOA 5DMSA 1E1ZP 5AJ9A 4YYPA 4HY2A 1E2SP 3Q1IA 3GYVA 1F34B 2IA9A 3HIKA 3FVHA 3LM3A 4N7VA 4H71A 3P35A 1FSUA 4LKLA 2N19A 4DFWA 4J7BB 1E3CP 4NK7A 3HFDA 3C5LA 4NKBA 1E2TA 3P36A 3RQ7A 4FDJA 4O56A 3LXQA 4WHHA 4X9WA 3HIHA 4H5XA 4E67A 4X9RA 4E9DA 2E50A 3KDRA 4E9CA 5J19A 4CXSA 3P37A 4RS6A 2UV8G 2I9ZA 1AUKA 4CXUA 4N7ZA 1A87A 5DNJA 2I9XA 3BZIA
chains in the Genus database with same CATH topology
4X9VA 3Q1IA 4O56A 2OJXA 3HIKA 4LKMA 3FVHA 4H71A 3P35A 4WHHA 4X9WA 4O9WA 5DMVC 3P2ZA 4WHKA 5LHZA 4LKLA 2N19A 3HIHA 4O6WA 3P34A 2OGQA 4H5XA 4E67A 4X9RA 4DFWA 4E9DA 1Q4KA 4WHLA 4J7BB 1UMWA 4XB0A 4HABA 3P2WA 4HCOA 5DMSA 4E9CA 5J19A 3C5LA 3P37A 4RCPA 4RS6A 4YYPA 4HY2A 1Q4OA 3P36A 3RQ7A 5DNJA 3BZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4X9V A;  3Q1I A;  4O56 A;  2OJX A;  3HIK A;  4LKM A;  3FVH A;  4H71 A;  3P35 A;  4WHH A;  4X9W A;  4O9W A;  5DMV C;  3P2Z A;  4WHK A;  5LHZ A;  4LKL A;  2N19 A;  3HIH A;  4O6W A;  3P34 A;  2OGQ A;  4H5X A;  4E67 A;  4X9R A;  4DFW A;  4E9D A;  1Q4K A;  4WHL A;  4J7B B;  1UMW A;  4XB0 A;  4HAB A;  3P2W A;  4HCO A;  5DMS A;  4E9C A;  5J19 A;  3C5L A;  3P37 A;  4RCP A;  4RS6 A;  4YYP A;  4HY2 A;  1Q4O A;  3P36 A;  3RQ7 A;  5DNJ A;  3BZI A; 
#chains in the Genus database with same CATH topology
 4X9V A;  4LKM A;  1E33 P;  4CXK A;  5DAY A;  5DMV C;  3HMJ G;  4O6W A;  2OGQ A;  2QZU A;  1Q4K A;  4N9J A;  1P49 A;  1N2L A;  3ED4 A;  3P2W A;  4XB0 A;  4CYR A;  4FDI A;  2VKZ G;  4RCP A;  1Q4O A;  3FS3 A;  1F32 A;  2OJX A;  4CYS A;  4O9W A;  1N2K A;  3P2Z A;  4WHK A;  5LHZ A;  4G7N A;  3P34 A;  3GYW A;  4WHL A;  1HDH A;  1UMW A;  4HAB A;  4HCO A;  5DMS A;  1E1Z P;  5AJ9 A;  4YYP A;  4HY2 A;  1E2S P;  3Q1I A;  3GYV A;  1F34 B;  2IA9 A;  3HIK A;  3FVH A;  3LM3 A;  4N7V A;  4H71 A;  3P35 A;  1FSU A;  4LKL A;  2N19 A;  4DFW A;  4J7B B;  1E3C P;  4NK7 A;  3HFD A;  3C5L A;  4NKB A;  1E2T A;  3P36 A;  3RQ7 A;  4FDJ A;  4O56 A;  3LXQ A;  4WHH A;  4X9W A;  3HIH A;  4H5X A;  4E67 A;  4X9R A;  4E9D A;  2E50 A;  3KDR A;  4E9C A;  5J19 A;  4CXS A;  3P37 A;  4RS6 A;  2UV8 G;  2I9Z A;  1AUK A;  4CXU A;  4N7Z A;  1A87 A;  5DNJ A;  2I9X A;  3BZI A; 
#chains in the Genus database with same CATH homology
 4X9V A;  3Q1I A;  4O56 A;  2OJX A;  3HIK A;  4LKM A;  3FVH A;  4H71 A;  3P35 A;  4WHH A;  4X9W A;  4O9W A;  5DMV C;  3P2Z A;  4WHK A;  5LHZ A;  4LKL A;  2N19 A;  3HIH A;  4O6W A;  3P34 A;  2OGQ A;  4H5X A;  4E67 A;  4X9R A;  4DFW A;  4E9D A;  1Q4K A;  4WHL A;  4J7B B;  1UMW A;  4XB0 A;  4HAB A;  3P2W A;  4HCO A;  5DMS A;  4E9C A;  5J19 A;  3C5L A;  3P37 A;  4RCP A;  4RS6 A;  4YYP A;  4HY2 A;  1Q4O A;  3P36 A;  3RQ7 A;  5DNJ A;  3BZI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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