3HIKA

Structure of human plk1-pbd in complex with plhspt
Total Genus 71
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
224
structure length
224
Chain Sequence
DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Serine/threonine-protein kinase PLK1
publication title Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
pubmed doi rcsb
source organism Homo sapiens
total genus 71
structure length 224
sequence length 224
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2009-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3hikA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3hikA01
5DNJA 4X9VA 2N19A 2OGQA 4E67A 4XB0A 1Q4KA 3P2ZA 4DFWA 4LKMA 3P35A 3P2WA 4RS6A 4WHHA 5LHZA 3FVHA 4YYPA 1UMWA 4HABA 4J7BB 4RCPA 4WHKA 5DMSA 3HIKA 4O6WA 4E9DA 4WHLA 4H5XA 3C5LA 3P34A 4O56A 3P36A 4HCOA 4X9RA 4H71A 5DMVC 4HY2A 1Q4OA 4LKLA 4X9WA 3BZIA 4E9CA 5J19A 2OJXA 3HIHA 3P37A 3Q1IA 3RQ7A 4O9WA
chains in the Genus database with same CATH superfamily
2N19A 2VKZG 3HMJG 1P49A 2IA9A 4G7NA 5AJ9A 3FVHA 1UMWA 4FDJA 4WHKA 4O6WA 4E9DA 4O56A 4CXKA 3P36A 4CXSA 4HY2A 4LKLA 2E50A 4X9WA 1N2LA 1E1ZP 4CYRA 3ED4A 2OGQA 1E2SP 1HDHA 4XB0A 1Q4KA 3P2ZA 3P35A 2UV8G 4WHHA 4N7VA 5LHZA 1E33P 4HABA 3LXQA 4RCPA 4CYSA 5DMSA 4N7ZA 3P34A 4H71A 4NK7A 2I9ZA 3FS3A 1A87A 1Q4OA 3HFDA 4N9JA 4E9CA 3HIHA 4NKBA 4O9WA 3GYWA 4X9VA 4E67A 1F34B 4LKMA 3P2WA 4RS6A 1E2TA 4YYPA 1N2KA 3HIKA 4WHLA 4H5XA 3C5LA 5DAYA 4HCOA 3GYVA 3BZIA 2OJXA 1E3CP 3P37A 3Q1IA 3RQ7A 2I9XA 5DNJA 1AUKA 1FSUA 4DFWA 2QZUA 4CXUA 3LM3A 4J7BB 1F32A 4FDIA 4X9RA 5DMVC 5J19A 3KDRA
chains in the Genus database with same CATH topology
5DNJA 4X9VA 2N19A 2OGQA 4E67A 4XB0A 1Q4KA 3P2ZA 4DFWA 4LKMA 3P35A 3P2WA 4RS6A 4WHHA 5LHZA 3FVHA 4YYPA 1UMWA 4HABA 4J7BB 4RCPA 4WHKA 5DMSA 3HIKA 4O6WA 4E9DA 4WHLA 4H5XA 3C5LA 3P34A 4O56A 3P36A 4HCOA 4X9RA 4H71A 5DMVC 4HY2A 1Q4OA 4LKLA 4X9WA 3BZIA 4E9CA 5J19A 2OJXA 3HIHA 3P37A 3Q1IA 3RQ7A 4O9WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DNJ A;  4X9V A;  2N19 A;  2OGQ A;  4E67 A;  4XB0 A;  1Q4K A;  3P2Z A;  4DFW A;  4LKM A;  3P35 A;  3P2W A;  4RS6 A;  4WHH A;  5LHZ A;  3FVH A;  4YYP A;  1UMW A;  4HAB A;  4J7B B;  4RCP A;  4WHK A;  5DMS A;  3HIK A;  4O6W A;  4E9D A;  4WHL A;  4H5X A;  3C5L A;  3P34 A;  4O56 A;  3P36 A;  4HCO A;  4X9R A;  4H71 A;  5DMV C;  4HY2 A;  1Q4O A;  4LKL A;  4X9W A;  3BZI A;  4E9C A;  5J19 A;  2OJX A;  3HIH A;  3P37 A;  3Q1I A;  3RQ7 A;  4O9W A; 
#chains in the Genus database with same CATH topology
 2N19 A;  2VKZ G;  3HMJ G;  1P49 A;  2IA9 A;  4G7N A;  5AJ9 A;  3FVH A;  1UMW A;  4FDJ A;  4WHK A;  4O6W A;  4E9D A;  4O56 A;  4CXK A;  3P36 A;  4CXS A;  4HY2 A;  4LKL A;  2E50 A;  4X9W A;  1N2L A;  1E1Z P;  4CYR A;  3ED4 A;  2OGQ A;  1E2S P;  1HDH A;  4XB0 A;  1Q4K A;  3P2Z A;  3P35 A;  2UV8 G;  4WHH A;  4N7V A;  5LHZ A;  1E33 P;  4HAB A;  3LXQ A;  4RCP A;  4CYS A;  5DMS A;  4N7Z A;  3P34 A;  4H71 A;  4NK7 A;  2I9Z A;  3FS3 A;  1A87 A;  1Q4O A;  3HFD A;  4N9J A;  4E9C A;  3HIH A;  4NKB A;  4O9W A;  3GYW A;  4X9V A;  4E67 A;  1F34 B;  4LKM A;  3P2W A;  4RS6 A;  1E2T A;  4YYP A;  1N2K A;  3HIK A;  4WHL A;  4H5X A;  3C5L A;  5DAY A;  4HCO A;  3GYV A;  3BZI A;  2OJX A;  1E3C P;  3P37 A;  3Q1I A;  3RQ7 A;  2I9X A;  5DNJ A;  1AUK A;  1FSU A;  4DFW A;  2QZU A;  4CXU A;  3LM3 A;  4J7B B;  1F32 A;  4FDI A;  4X9R A;  5DMV C;  5J19 A;  3KDR A; 
#chains in the Genus database with same CATH homology
 5DNJ A;  4X9V A;  2N19 A;  2OGQ A;  4E67 A;  4XB0 A;  1Q4K A;  3P2Z A;  4DFW A;  4LKM A;  3P35 A;  3P2W A;  4RS6 A;  4WHH A;  5LHZ A;  3FVH A;  4YYP A;  1UMW A;  4HAB A;  4J7B B;  4RCP A;  4WHK A;  5DMS A;  3HIK A;  4O6W A;  4E9D A;  4WHL A;  4H5X A;  3C5L A;  3P34 A;  4O56 A;  3P36 A;  4HCO A;  4X9R A;  4H71 A;  5DMV C;  4HY2 A;  1Q4O A;  4LKL A;  4X9W A;  3BZI A;  4E9C A;  5J19 A;  2OJX A;  3HIH A;  3P37 A;  3Q1I A;  3RQ7 A;  4O9W A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...