3HIKA

Structure of human plk1-pbd in complex with plhspt
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
224
structure length
224
Chain Sequence
DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords Serine/threonine-protein kinase PLK1
total genus 71
structure length 224
sequence length 224
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2009-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3hikA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3hikA01
3HIHA 2OJXA 5DMSA 3C5LA 3P37A 2N19A 4E9CA 3RQ7A 4O9WA 4E9DA 5DNJA 4WHHA 1Q4OA 4HABA 4RCPA 4X9RA 2OGQA 3BZIA 4O6WA 4HCOA 4O56A 4X9VA 3FVHA 3P2WA 1UMWA 4H5XA 3Q1IA 1Q4KA 4HY2A 4X9WA 3HIKA 4XB0A 5DMVC 4DFWA 3P2ZA 5J19A 4J7BB 4WHKA 4YYPA 4H71A 3P35A 4WHLA 5LHZA 4E67A 3P34A 4LKMA 4RS6A 3P36A 4LKLA
chains in the Genus database with same CATH superfamily
1HDHA 2IA9A 2N19A 3HFDA 3RQ7A 4O9WA 4NKBA 2E50A 4X9VA 2UV8G 1E1ZP 3P2WA 3Q1IA 1FSUA 3LM3A 4HY2A 4X9WA 1E3CP 3HIKA 5DMVC 4WHKA 3P35A 4WHLA 5LHZA 3ED4A 3P36A 3FS3A 3HIHA 4CYSA 3P37A 1AUKA 4E9CA 1P49A 1N2KA 4X9RA 2OGQA 3BZIA 4O6WA 4CXSA 4N7VA 5DAYA 1UMWA 4FDIA 4XB0A 3P2ZA 4N7ZA 1F34B 1F32A 4YYPA 4H71A 1E2SP 3LXQA 4LKLA 2QZUA 3C5LA 4E9DA 3KDRA 1Q4OA 3GYVA 4RCPA 5AJ9A 4G7NA 4HCOA 3FVHA 4H5XA 1N2LA 3GYWA 5J19A 4FDJA 4E67A 3P34A 4CXKA 2I9XA 4CXUA 2OJXA 5DMSA 1E33P 4CYRA 1A87A 2VKZG 5DNJA 2I9ZA 1E2TA 4HABA 4O56A 4N9JA 4NK7A 1Q4KA 4DFWA 4J7BB 4LKMA 4RS6A 3HMJG 4WHHA
chains in the Genus database with same CATH topology
3HIHA 2OJXA 5DMSA 3C5LA 3P37A 2N19A 4E9CA 3RQ7A 4O9WA 4E9DA 5DNJA 4WHHA 1Q4OA 4HABA 4RCPA 4X9RA 2OGQA 3BZIA 4O6WA 4HCOA 4O56A 4X9VA 3FVHA 3P2WA 1UMWA 4H5XA 3Q1IA 1Q4KA 4HY2A 4X9WA 3HIKA 4XB0A 5DMVC 4DFWA 3P2ZA 5J19A 4J7BB 4WHKA 4YYPA 4H71A 3P35A 4WHLA 5LHZA 4E67A 3P34A 4LKMA 4RS6A 3P36A 4LKLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HIH A;  2OJX A;  5DMS A;  3C5L A;  3P37 A;  2N19 A;  4E9C A;  3RQ7 A;  4O9W A;  4E9D A;  5DNJ A;  4WHH A;  1Q4O A;  4HAB A;  4RCP A;  4X9R A;  2OGQ A;  3BZI A;  4O6W A;  4HCO A;  4O56 A;  4X9V A;  3FVH A;  3P2W A;  1UMW A;  4H5X A;  3Q1I A;  1Q4K A;  4HY2 A;  4X9W A;  3HIK A;  4XB0 A;  5DMV C;  4DFW A;  3P2Z A;  5J19 A;  4J7B B;  4WHK A;  4YYP A;  4H71 A;  3P35 A;  4WHL A;  5LHZ A;  4E67 A;  3P34 A;  4LKM A;  4RS6 A;  3P36 A;  4LKL A; 
#chains in the Genus database with same CATH topology
 1HDH A;  2IA9 A;  2N19 A;  3HFD A;  3RQ7 A;  4O9W A;  4NKB A;  2E50 A;  4X9V A;  2UV8 G;  1E1Z P;  3P2W A;  3Q1I A;  1FSU A;  3LM3 A;  4HY2 A;  4X9W A;  1E3C P;  3HIK A;  5DMV C;  4WHK A;  3P35 A;  4WHL A;  5LHZ A;  3ED4 A;  3P36 A;  3FS3 A;  3HIH A;  4CYS A;  3P37 A;  1AUK A;  4E9C A;  1P49 A;  1N2K A;  4X9R A;  2OGQ A;  3BZI A;  4O6W A;  4CXS A;  4N7V A;  5DAY A;  1UMW A;  4FDI A;  4XB0 A;  3P2Z A;  4N7Z A;  1F34 B;  1F32 A;  4YYP A;  4H71 A;  1E2S P;  3LXQ A;  4LKL A;  2QZU A;  3C5L A;  4E9D A;  3KDR A;  1Q4O A;  3GYV A;  4RCP A;  5AJ9 A;  4G7N A;  4HCO A;  3FVH A;  4H5X A;  1N2L A;  3GYW A;  5J19 A;  4FDJ A;  4E67 A;  3P34 A;  4CXK A;  2I9X A;  4CXU A;  2OJX A;  5DMS A;  1E33 P;  4CYR A;  1A87 A;  2VKZ G;  5DNJ A;  2I9Z A;  1E2T A;  4HAB A;  4O56 A;  4N9J A;  4NK7 A;  1Q4K A;  4DFW A;  4J7B B;  4LKM A;  4RS6 A;  3HMJ G;  4WHH A; 
#chains in the Genus database with same CATH homology
 3HIH A;  2OJX A;  5DMS A;  3C5L A;  3P37 A;  2N19 A;  4E9C A;  3RQ7 A;  4O9W A;  4E9D A;  5DNJ A;  4WHH A;  1Q4O A;  4HAB A;  4RCP A;  4X9R A;  2OGQ A;  3BZI A;  4O6W A;  4HCO A;  4O56 A;  4X9V A;  3FVH A;  3P2W A;  1UMW A;  4H5X A;  3Q1I A;  1Q4K A;  4HY2 A;  4X9W A;  3HIK A;  4XB0 A;  5DMV C;  4DFW A;  3P2Z A;  5J19 A;  4J7B B;  4WHK A;  4YYP A;  4H71 A;  3P35 A;  4WHL A;  5LHZ A;  4E67 A;  3P34 A;  4LKM A;  4RS6 A;  3P36 A;  4LKL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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