5DMSA

Mouse polo-box domain and emi2 (169-177)
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
226
structure length
226
Chain Sequence
EAIECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
pubmed doi rcsb
source organism Mus musculus
molecule tags Transferase/metal binding protein
total genus 76
structure length 226
sequence length 226
chains with identical sequence C
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2015-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dmsA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dmsA01
3C5LA 3P2ZA 4J7BB 4E9CA 4HY2A 4HCOA 4WHLA 3P37A 4O56A 4O6WA 4RCPA 4WHHA 4LKLA 4RS6A 4O9WA 3HIKA 1Q4OA 4LKMA 3P36A 5J19A 4E9DA 4WHKA 4YYPA 4E67A 4HABA 4H71A 4X9RA 4DFWA 5LHZA 5DMVC 2OJXA 3FVHA 3RQ7A 3P35A 2N19A 2OGQA 3P34A 3BZIA 3HIHA 4X9WA 4X9VA 3P2WA 4H5XA 4XB0A 5DMSA 3Q1IA 5DNJA 1Q4KA 1UMWA
chains in the Genus database with same CATH superfamily
5AJ9A 4J7BB 3P37A 4O56A 3HMJG 4RCPA 4WHHA 4LKMA 1E2SP 2I9ZA 5LHZA 3HFDA 4CXUA 4X9WA 4X9VA 3P2WA 4H5XA 4CXSA 5DNJA 3C5LA 3P2ZA 4WHLA 1N2KA 4LKLA 3FS3A 1Q4OA 1F32A 5J19A 4CXKA 4CYSA 1A87A 4H71A 3LXQA 4DFWA 1E3CP 4NKBA 3P34A 3HIHA 4XB0A 4FDIA 5DMSA 3KDRA 1UMWA 4HCOA 5DAYA 1F34B 1AUKA 2VKZG 4RS6A 3ED4A 2QZUA 1N2LA 1FSUA 1P49A 4N7ZA 4E67A 4HABA 4X9RA 3GYVA 2OJXA 3P35A 2OGQA 3BZIA 4FDJA 2E50A 1HDHA 4E9CA 4HY2A 4O6WA 2UV8G 3Q1IA 4O9WA 3HIKA 4N9JA 1E33P 2I9XA 1E2TA 3P36A 4E9DA 4NK7A 4WHKA 4N7VA 3LM3A 4YYPA 5DMVC 3GYWA 3RQ7A 3FVHA 2N19A 4CYRA 2IA9A 4G7NA 1E1ZP 1Q4KA
chains in the Genus database with same CATH topology
3C5LA 3P2ZA 4J7BB 4E9CA 4HY2A 4HCOA 4WHLA 3P37A 4O56A 4O6WA 4RCPA 4WHHA 4LKLA 4RS6A 4O9WA 3HIKA 1Q4OA 4LKMA 3P36A 5J19A 4E9DA 4WHKA 4YYPA 4E67A 4HABA 4H71A 4X9RA 4DFWA 5LHZA 5DMVC 2OJXA 3FVHA 3RQ7A 3P35A 2N19A 2OGQA 3P34A 3BZIA 3HIHA 4X9WA 4X9VA 3P2WA 4H5XA 4XB0A 5DMSA 3Q1IA 5DNJA 1Q4KA 1UMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C5L A;  3P2Z A;  4J7B B;  4E9C A;  4HY2 A;  4HCO A;  4WHL A;  3P37 A;  4O56 A;  4O6W A;  4RCP A;  4WHH A;  4LKL A;  4RS6 A;  4O9W A;  3HIK A;  1Q4O A;  4LKM A;  3P36 A;  5J19 A;  4E9D A;  4WHK A;  4YYP A;  4E67 A;  4HAB A;  4H71 A;  4X9R A;  4DFW A;  5LHZ A;  5DMV C;  2OJX A;  3FVH A;  3RQ7 A;  3P35 A;  2N19 A;  2OGQ A;  3P34 A;  3BZI A;  3HIH A;  4X9W A;  4X9V A;  3P2W A;  4H5X A;  4XB0 A;  5DMS A;  3Q1I A;  5DNJ A;  1Q4K A;  1UMW A; 
#chains in the Genus database with same CATH topology
 5AJ9 A;  4J7B B;  3P37 A;  4O56 A;  3HMJ G;  4RCP A;  4WHH A;  4LKM A;  1E2S P;  2I9Z A;  5LHZ A;  3HFD A;  4CXU A;  4X9W A;  4X9V A;  3P2W A;  4H5X A;  4CXS A;  5DNJ A;  3C5L A;  3P2Z A;  4WHL A;  1N2K A;  4LKL A;  3FS3 A;  1Q4O A;  1F32 A;  5J19 A;  4CXK A;  4CYS A;  1A87 A;  4H71 A;  3LXQ A;  4DFW A;  1E3C P;  4NKB A;  3P34 A;  3HIH A;  4XB0 A;  4FDI A;  5DMS A;  3KDR A;  1UMW A;  4HCO A;  5DAY A;  1F34 B;  1AUK A;  2VKZ G;  4RS6 A;  3ED4 A;  2QZU A;  1N2L A;  1FSU A;  1P49 A;  4N7Z A;  4E67 A;  4HAB A;  4X9R A;  3GYV A;  2OJX A;  3P35 A;  2OGQ A;  3BZI A;  4FDJ A;  2E50 A;  1HDH A;  4E9C A;  4HY2 A;  4O6W A;  2UV8 G;  3Q1I A;  4O9W A;  3HIK A;  4N9J A;  1E33 P;  2I9X A;  1E2T A;  3P36 A;  4E9D A;  4NK7 A;  4WHK A;  4N7V A;  3LM3 A;  4YYP A;  5DMV C;  3GYW A;  3RQ7 A;  3FVH A;  2N19 A;  4CYR A;  2IA9 A;  4G7N A;  1E1Z P;  1Q4K A; 
#chains in the Genus database with same CATH homology
 3C5L A;  3P2Z A;  4J7B B;  4E9C A;  4HY2 A;  4HCO A;  4WHL A;  3P37 A;  4O56 A;  4O6W A;  4RCP A;  4WHH A;  4LKL A;  4RS6 A;  4O9W A;  3HIK A;  1Q4O A;  4LKM A;  3P36 A;  5J19 A;  4E9D A;  4WHK A;  4YYP A;  4E67 A;  4HAB A;  4H71 A;  4X9R A;  4DFW A;  5LHZ A;  5DMV C;  2OJX A;  3FVH A;  3RQ7 A;  3P35 A;  2N19 A;  2OGQ A;  3P34 A;  3BZI A;  3HIH A;  4X9W A;  4X9V A;  3P2W A;  4H5X A;  4XB0 A;  5DMS A;  3Q1I A;  5DNJ A;  1Q4K A;  1UMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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