5DMSA

Mouse polo-box domain and emi2 (169-177)
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
226
structure length
226
Chain Sequence
b'EAIECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
pubmed doi rcsb
source organism Mus musculus
molecule tags Transferase/metal binding protein
total genus 76
structure length 226
sequence length 226
chains with identical sequence C
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2015-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dmsA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dmsA01
3P2ZA 5DMVC 4H5XA 4HY2A 4YYPA 3HIHA 4X9WA 4RS6A 3BZIA 4LKMA 4LKLA 2OJXA 3P35A 4HABA 4X9RA 4X9VA 1UMWA 3Q1IA 3HIKA 4O6WA 3C5LA 1Q4OA 4E9DA 2OGQA 3P2WA 1Q4KA 4RCPA 3P37A 4H71A 4E67A 3RQ7A 5DNJA 3P36A 4O9WA 4XB0A 5LHZA 4DFWA 4WHLA 5J19A 4E9CA 3FVHA 4HCOA 3P34A 4O56A 4WHKA 4WHHA 4J7BB 2N19A 5DMSA
chains in the Genus database with same CATH superfamily
4HY2A 3HIHA 3GYVA 4CYSA 4LKLA 4X9VA 4CXSA 1Q4KA 3LM3A 3P2WA 4E67A 4NK7A 4CXUA 3P36A 1F32A 3FVHA 4O56A 4WHHA 3HMJG 3P2ZA 4H5XA 1FSUA 3BZIA 1F34B 2OJXA 4N7VA 1E2SP 3GYWA 3Q1IA 3HIKA 2I9XA 2E50A 4RCPA 3P37A 3KDRA 4O9WA 4XB0A 2IA9A 4DFWA 4N9JA 4CYRA 3ED4A 4WHKA 5DMSA 1N2KA 3HFDA 4X9WA 4RS6A 1N2LA 3P35A 4HABA 1E2TA 2I9ZA 4G7NA 5DAYA 1HDHA 3C5LA 4E9DA 4FDIA 2QZUA 4N7ZA 1E1ZP 3RQ7A 1A87A 4CXKA 4NKBA 4WHLA 4HCOA 4LKMA 4J7BB 2VKZG 1E33P 5DMVC 4YYPA 1AUKA 4FDJA 1E3CP 4X9RA 1UMWA 2UV8G 4O6WA 1Q4OA 2OGQA 4H71A 5DNJA 3FS3A 5LHZA 5J19A 4E9CA 5AJ9A 3P34A 3LXQA 1P49A 2N19A
chains in the Genus database with same CATH topology
3P2ZA 5DMVC 4H5XA 4HY2A 4YYPA 3HIHA 4X9WA 4RS6A 3BZIA 4LKMA 4LKLA 2OJXA 3P35A 4HABA 4X9RA 4X9VA 1UMWA 3Q1IA 3HIKA 4O6WA 3C5LA 1Q4OA 4E9DA 2OGQA 3P2WA 1Q4KA 4RCPA 3P37A 4H71A 4E67A 3RQ7A 5DNJA 3P36A 4O9WA 4XB0A 5LHZA 4DFWA 4WHLA 5J19A 4E9CA 3FVHA 4HCOA 3P34A 4O56A 4WHKA 4WHHA 4J7BB 2N19A 5DMSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P2Z A;  5DMV C;  4H5X A;  4HY2 A;  4YYP A;  3HIH A;  4X9W A;  4RS6 A;  3BZI A;  4LKM A;  4LKL A;  2OJX A;  3P35 A;  4HAB A;  4X9R A;  4X9V A;  1UMW A;  3Q1I A;  3HIK A;  4O6W A;  3C5L A;  1Q4O A;  4E9D A;  2OGQ A;  3P2W A;  1Q4K A;  4RCP A;  3P37 A;  4H71 A;  4E67 A;  3RQ7 A;  5DNJ A;  3P36 A;  4O9W A;  4XB0 A;  5LHZ A;  4DFW A;  4WHL A;  5J19 A;  4E9C A;  3FVH A;  4HCO A;  3P34 A;  4O56 A;  4WHK A;  4WHH A;  4J7B B;  2N19 A;  5DMS A; 
#chains in the Genus database with same CATH topology
 4HY2 A;  3HIH A;  3GYV A;  4CYS A;  4LKL A;  4X9V A;  4CXS A;  1Q4K A;  3LM3 A;  3P2W A;  4E67 A;  4NK7 A;  4CXU A;  3P36 A;  1F32 A;  3FVH A;  4O56 A;  4WHH A;  3HMJ G;  3P2Z A;  4H5X A;  1FSU A;  3BZI A;  1F34 B;  2OJX A;  4N7V A;  1E2S P;  3GYW A;  3Q1I A;  3HIK A;  2I9X A;  2E50 A;  4RCP A;  3P37 A;  3KDR A;  4O9W A;  4XB0 A;  2IA9 A;  4DFW A;  4N9J A;  4CYR A;  3ED4 A;  4WHK A;  5DMS A;  1N2K A;  3HFD A;  4X9W A;  4RS6 A;  1N2L A;  3P35 A;  4HAB A;  1E2T A;  2I9Z A;  4G7N A;  5DAY A;  1HDH A;  3C5L A;  4E9D A;  4FDI A;  2QZU A;  4N7Z A;  1E1Z P;  3RQ7 A;  1A87 A;  4CXK A;  4NKB A;  4WHL A;  4HCO A;  4LKM A;  4J7B B;  2VKZ G;  1E33 P;  5DMV C;  4YYP A;  1AUK A;  4FDJ A;  1E3C P;  4X9R A;  1UMW A;  2UV8 G;  4O6W A;  1Q4O A;  2OGQ A;  4H71 A;  5DNJ A;  3FS3 A;  5LHZ A;  5J19 A;  4E9C A;  5AJ9 A;  3P34 A;  3LXQ A;  1P49 A;  2N19 A; 
#chains in the Genus database with same CATH homology
 3P2Z A;  5DMV C;  4H5X A;  4HY2 A;  4YYP A;  3HIH A;  4X9W A;  4RS6 A;  3BZI A;  4LKM A;  4LKL A;  2OJX A;  3P35 A;  4HAB A;  4X9R A;  4X9V A;  1UMW A;  3Q1I A;  3HIK A;  4O6W A;  3C5L A;  1Q4O A;  4E9D A;  2OGQ A;  3P2W A;  1Q4K A;  4RCP A;  3P37 A;  4H71 A;  4E67 A;  3RQ7 A;  5DNJ A;  3P36 A;  4O9W A;  4XB0 A;  5LHZ A;  4DFW A;  4WHL A;  5J19 A;  4E9C A;  3FVH A;  4HCO A;  3P34 A;  4O56 A;  4WHK A;  4WHH A;  4J7B B;  2N19 A;  5DMS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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