5DMSA

Mouse polo-box domain and emi2 (169-177)
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
226
structure length
226
Chain Sequence
EAIECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase/metal binding protein
molecule keywords Serine/threonine-protein kinase PLK1
publication title Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
pubmed doi rcsb
source organism Mus musculus
total genus 76
structure length 226
sequence length 226
chains with identical sequence C
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2015-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dmsA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dmsA01
3RQ7A 3P37A 4X9RA 4XB0A 3P35A 4RS6A 4YYPA 3HIHA 4HABA 4X9WA 4X9VA 5DNJA 4O9WA 3HIKA 2OGQA 3FVHA 3C5LA 5DMSA 2OJXA 4H71A 4WHHA 5LHZA 4LKLA 4DFWA 4WHLA 4HY2A 5DMVC 4H5XA 1Q4OA 4RCPA 4O56A 4E67A 1Q4KA 1UMWA 4J7BB 4E9CA 2N19A 4O6WA 4HCOA 4LKMA 3P2WA 5J19A 3P34A 3P36A 3BZIA 4E9DA 3P2ZA 3Q1IA 4WHKA
chains in the Genus database with same CATH superfamily
3P37A 4X9RA 4CYSA 3P35A 3HIHA 1N2LA 3HIKA 3FVHA 5DMSA 4N7VA 4WHHA 3LXQA 4RCPA 1Q4KA 4G7NA 4E9CA 2N19A 2E50A 2I9XA 4HCOA 1F34B 3KDRA 3P36A 3RQ7A 4FDJA 4NK7A 1E33P 4HABA 5DAYA 2OGQA 4N9JA 2QZUA 5AJ9A 4CXUA 2OJXA 5LHZA 2IA9A 4HY2A 1UMWA 1N2KA 1AUKA 4O6WA 1P49A 3P2WA 4CYRA 1A87A 3BZIA 1E2TA 4WHKA 2UV8G 4XB0A 4CXSA 1E1ZP 1FSUA 4RS6A 4YYPA 3GYVA 3HFDA 3ED4A 1HDHA 1F32A 4H71A 4LKLA 4FDIA 4WHLA 4O56A 4E67A 3GYWA 2I9ZA 4LKMA 1E2SP 5J19A 3P34A 3LM3A 4NKBA 4X9WA 4X9VA 5DNJA 3HMJG 2VKZG 4O9WA 1E3CP 3C5LA 4DFWA 5DMVC 1Q4OA 4H5XA 4J7BB 3FS3A 4CXKA 4E9DA 3P2ZA 3Q1IA 4N7ZA
chains in the Genus database with same CATH topology
3RQ7A 3P37A 4X9RA 4XB0A 3P35A 4RS6A 4YYPA 3HIHA 4HABA 4X9WA 4X9VA 5DNJA 4O9WA 3HIKA 2OGQA 3FVHA 3C5LA 5DMSA 2OJXA 4H71A 4WHHA 5LHZA 4LKLA 4DFWA 4WHLA 4HY2A 5DMVC 4H5XA 1Q4OA 4RCPA 4O56A 4E67A 1Q4KA 1UMWA 4J7BB 4E9CA 2N19A 4O6WA 4HCOA 4LKMA 3P2WA 5J19A 3P34A 3P36A 3BZIA 4E9DA 3P2ZA 3Q1IA 4WHKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RQ7 A;  3P37 A;  4X9R A;  4XB0 A;  3P35 A;  4RS6 A;  4YYP A;  3HIH A;  4HAB A;  4X9W A;  4X9V A;  5DNJ A;  4O9W A;  3HIK A;  2OGQ A;  3FVH A;  3C5L A;  5DMS A;  2OJX A;  4H71 A;  4WHH A;  5LHZ A;  4LKL A;  4DFW A;  4WHL A;  4HY2 A;  5DMV C;  4H5X A;  1Q4O A;  4RCP A;  4O56 A;  4E67 A;  1Q4K A;  1UMW A;  4J7B B;  4E9C A;  2N19 A;  4O6W A;  4HCO A;  4LKM A;  3P2W A;  5J19 A;  3P34 A;  3P36 A;  3BZI A;  4E9D A;  3P2Z A;  3Q1I A;  4WHK A; 
#chains in the Genus database with same CATH topology
 3P37 A;  4X9R A;  4CYS A;  3P35 A;  3HIH A;  1N2L A;  3HIK A;  3FVH A;  5DMS A;  4N7V A;  4WHH A;  3LXQ A;  4RCP A;  1Q4K A;  4G7N A;  4E9C A;  2N19 A;  2E50 A;  2I9X A;  4HCO A;  1F34 B;  3KDR A;  3P36 A;  3RQ7 A;  4FDJ A;  4NK7 A;  1E33 P;  4HAB A;  5DAY A;  2OGQ A;  4N9J A;  2QZU A;  5AJ9 A;  4CXU A;  2OJX A;  5LHZ A;  2IA9 A;  4HY2 A;  1UMW A;  1N2K A;  1AUK A;  4O6W A;  1P49 A;  3P2W A;  4CYR A;  1A87 A;  3BZI A;  1E2T A;  4WHK A;  2UV8 G;  4XB0 A;  4CXS A;  1E1Z P;  1FSU A;  4RS6 A;  4YYP A;  3GYV A;  3HFD A;  3ED4 A;  1HDH A;  1F32 A;  4H71 A;  4LKL A;  4FDI A;  4WHL A;  4O56 A;  4E67 A;  3GYW A;  2I9Z A;  4LKM A;  1E2S P;  5J19 A;  3P34 A;  3LM3 A;  4NKB A;  4X9W A;  4X9V A;  5DNJ A;  3HMJ G;  2VKZ G;  4O9W A;  1E3C P;  3C5L A;  4DFW A;  5DMV C;  1Q4O A;  4H5X A;  4J7B B;  3FS3 A;  4CXK A;  4E9D A;  3P2Z A;  3Q1I A;  4N7Z A; 
#chains in the Genus database with same CATH homology
 3RQ7 A;  3P37 A;  4X9R A;  4XB0 A;  3P35 A;  4RS6 A;  4YYP A;  3HIH A;  4HAB A;  4X9W A;  4X9V A;  5DNJ A;  4O9W A;  3HIK A;  2OGQ A;  3FVH A;  3C5L A;  5DMS A;  2OJX A;  4H71 A;  4WHH A;  5LHZ A;  4LKL A;  4DFW A;  4WHL A;  4HY2 A;  5DMV C;  4H5X A;  1Q4O A;  4RCP A;  4O56 A;  4E67 A;  1Q4K A;  1UMW A;  4J7B B;  4E9C A;  2N19 A;  4O6W A;  4HCO A;  4LKM A;  3P2W A;  5J19 A;  3P34 A;  3P36 A;  3BZI A;  4E9D A;  3P2Z A;  3Q1I A;  4WHK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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