5DNJA

Mouse polo-box domain and peptide analog 702
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
221
structure length
215
Chain Sequence
HLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPRELPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
pubmed doi rcsb
source organism Mus musculus
molecule tags Transferase/transferase inhibitor
total genus 70
structure length 215
sequence length 221
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2015-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dnjA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dnjA01
4E9CA 4YYPA 4RS6A 2OJXA 5DMSA 5DNJA 4HCOA 4H5XA 4O9WA 3HIHA 4O6WA 4HABA 4WHLA 4LKLA 4DFWA 3Q1IA 3BZIA 4WHHA 4LKMA 3P35A 5LHZA 4WHKA 2OGQA 3P2WA 4O56A 3P37A 4X9RA 4XB0A 1Q4OA 4HY2A 1Q4KA 4H71A 5J19A 4E67A 4E9DA 4X9VA 5DMVC 2N19A 3P36A 3C5LA 4X9WA 3RQ7A 4J7BB 3HIKA 3P34A 3P2ZA 4RCPA 3FVHA 1UMWA
chains in the Genus database with same CATH superfamily
4YYPA 5DNJA 3LM3A 5AJ9A 1N2KA 4FDJA 3ED4A 4HABA 4NK7A 2IA9A 4WHHA 3P35A 4O56A 4XB0A 1Q4KA 4H71A 3GYWA 5J19A 1E33P 3RQ7A 3P34A 4CYRA 3P2ZA 1UMWA 4E9CA 4RS6A 4O9WA 4O6WA 4WHLA 4CXKA 2VKZG 5LHZA 2I9ZA 4X9RA 1Q4OA 4HY2A 2E50A 1E3CP 3HIKA 4RCPA 1A87A 4G7NA 2OJXA 1F32A 4HCOA 3LXQA 4NKBA 1FSUA 4N7VA 3HIHA 3HMJG 4CYSA 4LKMA 3P2WA 1F34B 3P37A 4CXUA 1E2SP 4E9DA 4X9WA 4J7BB 3HFDA 1AUKA 5DAYA 5DMSA 1E1ZP 2UV8G 4H5XA 1HDHA 4LKLA 4DFWA 3Q1IA 3BZIA 3FS3A 2I9XA 4FDIA 4WHKA 4CXSA 3KDRA 2OGQA 1P49A 4N7ZA 1E2TA 4E67A 1N2LA 4X9VA 2N19A 3P36A 3C5LA 5DMVC 4N9JA 2QZUA 3GYVA 3FVHA
chains in the Genus database with same CATH topology
4E9CA 4YYPA 4RS6A 2OJXA 5DMSA 5DNJA 4HCOA 4H5XA 4O9WA 3HIHA 4O6WA 4HABA 4WHLA 4LKLA 4DFWA 3Q1IA 3BZIA 4WHHA 4LKMA 3P35A 5LHZA 4WHKA 2OGQA 3P2WA 4O56A 3P37A 4X9RA 4XB0A 1Q4OA 4HY2A 1Q4KA 4H71A 5J19A 4E67A 4E9DA 4X9VA 5DMVC 2N19A 3P36A 3C5LA 4X9WA 3RQ7A 4J7BB 3HIKA 3P34A 3P2ZA 4RCPA 3FVHA 1UMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E9C A;  4YYP A;  4RS6 A;  2OJX A;  5DMS A;  5DNJ A;  4HCO A;  4H5X A;  4O9W A;  3HIH A;  4O6W A;  4HAB A;  4WHL A;  4LKL A;  4DFW A;  3Q1I A;  3BZI A;  4WHH A;  4LKM A;  3P35 A;  5LHZ A;  4WHK A;  2OGQ A;  3P2W A;  4O56 A;  3P37 A;  4X9R A;  4XB0 A;  1Q4O A;  4HY2 A;  1Q4K A;  4H71 A;  5J19 A;  4E67 A;  4E9D A;  4X9V A;  5DMV C;  2N19 A;  3P36 A;  3C5L A;  4X9W A;  3RQ7 A;  4J7B B;  3HIK A;  3P34 A;  3P2Z A;  4RCP A;  3FVH A;  1UMW A; 
#chains in the Genus database with same CATH topology
 4YYP A;  5DNJ A;  3LM3 A;  5AJ9 A;  1N2K A;  4FDJ A;  3ED4 A;  4HAB A;  4NK7 A;  2IA9 A;  4WHH A;  3P35 A;  4O56 A;  4XB0 A;  1Q4K A;  4H71 A;  3GYW A;  5J19 A;  1E33 P;  3RQ7 A;  3P34 A;  4CYR A;  3P2Z A;  1UMW A;  4E9C A;  4RS6 A;  4O9W A;  4O6W A;  4WHL A;  4CXK A;  2VKZ G;  5LHZ A;  2I9Z A;  4X9R A;  1Q4O A;  4HY2 A;  2E50 A;  1E3C P;  3HIK A;  4RCP A;  1A87 A;  4G7N A;  2OJX A;  1F32 A;  4HCO A;  3LXQ A;  4NKB A;  1FSU A;  4N7V A;  3HIH A;  3HMJ G;  4CYS A;  4LKM A;  3P2W A;  1F34 B;  3P37 A;  4CXU A;  1E2S P;  4E9D A;  4X9W A;  4J7B B;  3HFD A;  1AUK A;  5DAY A;  5DMS A;  1E1Z P;  2UV8 G;  4H5X A;  1HDH A;  4LKL A;  4DFW A;  3Q1I A;  3BZI A;  3FS3 A;  2I9X A;  4FDI A;  4WHK A;  4CXS A;  3KDR A;  2OGQ A;  1P49 A;  4N7Z A;  1E2T A;  4E67 A;  1N2L A;  4X9V A;  2N19 A;  3P36 A;  3C5L A;  5DMV C;  4N9J A;  2QZU A;  3GYV A;  3FVH A; 
#chains in the Genus database with same CATH homology
 4E9C A;  4YYP A;  4RS6 A;  2OJX A;  5DMS A;  5DNJ A;  4HCO A;  4H5X A;  4O9W A;  3HIH A;  4O6W A;  4HAB A;  4WHL A;  4LKL A;  4DFW A;  3Q1I A;  3BZI A;  4WHH A;  4LKM A;  3P35 A;  5LHZ A;  4WHK A;  2OGQ A;  3P2W A;  4O56 A;  3P37 A;  4X9R A;  4XB0 A;  1Q4O A;  4HY2 A;  1Q4K A;  4H71 A;  5J19 A;  4E67 A;  4E9D A;  4X9V A;  5DMV C;  2N19 A;  3P36 A;  3C5L A;  4X9W A;  3RQ7 A;  4J7B B;  3HIK A;  3P34 A;  3P2Z A;  4RCP A;  3FVH A;  1UMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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