5DNJA

Mouse polo-box domain and peptide analog 702
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
221
structure length
215
Chain Sequence
HLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPRELPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
pubmed doi rcsb
source organism Mus musculus
molecule tags Transferase/transferase inhibitor
molecule keywords Serine/threonine-protein kinase PLK1
total genus 70
structure length 215
sequence length 221
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2015-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dnjA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5dnjA01
4WHKA 4LKLA 3BZIA 4O6WA 4RS6A 4HY2A 5LHZA 4DFWA 4WHHA 3P37A 3P36A 4XB0A 1UMWA 1Q4KA 5J19A 4X9RA 4O9WA 4RCPA 4J7BB 4HABA 3P34A 4O56A 4X9VA 5DNJA 2N19A 4E9DA 3P2ZA 4WHLA 3HIKA 4X9WA 3P2WA 4E67A 3HIHA 4YYPA 4H5XA 4HCOA 3RQ7A 4H71A 5DMSA 2OJXA 5DMVC 3P35A 4LKMA 4E9CA 2OGQA 1Q4OA 3Q1IA 3FVHA 3C5LA
chains in the Genus database with same CATH superfamily
4FDIA 1P49A 1F32A 3LXQA 4XB0A 4NKBA 1A87A 4RCPA 4J7BB 4HABA 5AJ9A 4YYPA 4H5XA 4H71A 4N7VA 4NK7A 1Q4OA 3ED4A 1E2SP 3Q1IA 4N9JA 4O56A 3KDRA 2E50A 4O6WA 2IA9A 4RS6A 3HFDA 4DFWA 1HDHA 1E2TA 1E1ZP 1Q4KA 3LM3A 5J19A 2I9ZA 3P34A 4X9VA 2UV8G 5DAYA 4WHLA 4G7NA 3P2WA 3GYVA 3GYWA 2QZUA 4HCOA 4E9CA 1FSUA 4O9WA 4WHKA 4CXUA 4LKLA 3BZIA 3FS3A 5LHZA 1N2LA 3P37A 3P36A 2VKZG 4X9RA 5DNJA 2N19A 4E9DA 3HIKA 4E67A 5DMSA 3P35A 1AUKA 3FVHA 4CYSA 4HY2A 1E3CP 4WHHA 1UMWA 4CXKA 1F34B 3HMJG 4CYRA 4CXSA 3P2ZA 4X9WA 3HIHA 1E33P 2I9XA 3RQ7A 4FDJA 2OJXA 4N7ZA 5DMVC 4LKMA 2OGQA 1N2KA 3C5LA
chains in the Genus database with same CATH topology
4WHKA 4LKLA 3BZIA 4O6WA 4RS6A 4HY2A 5LHZA 4DFWA 4WHHA 3P37A 3P36A 4XB0A 1UMWA 1Q4KA 5J19A 4X9RA 4O9WA 4RCPA 4J7BB 4HABA 3P34A 4O56A 4X9VA 5DNJA 2N19A 4E9DA 3P2ZA 4WHLA 3HIKA 4X9WA 3P2WA 4E67A 3HIHA 4YYPA 4H5XA 4HCOA 3RQ7A 4H71A 5DMSA 2OJXA 5DMVC 3P35A 4LKMA 4E9CA 2OGQA 1Q4OA 3Q1IA 3FVHA 3C5LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WHK A;  4LKL A;  3BZI A;  4O6W A;  4RS6 A;  4HY2 A;  5LHZ A;  4DFW A;  4WHH A;  3P37 A;  3P36 A;  4XB0 A;  1UMW A;  1Q4K A;  5J19 A;  4X9R A;  4O9W A;  4RCP A;  4J7B B;  4HAB A;  3P34 A;  4O56 A;  4X9V A;  5DNJ A;  2N19 A;  4E9D A;  3P2Z A;  4WHL A;  3HIK A;  4X9W A;  3P2W A;  4E67 A;  3HIH A;  4YYP A;  4H5X A;  4HCO A;  3RQ7 A;  4H71 A;  5DMS A;  2OJX A;  5DMV C;  3P35 A;  4LKM A;  4E9C A;  2OGQ A;  1Q4O A;  3Q1I A;  3FVH A;  3C5L A; 
#chains in the Genus database with same CATH topology
 4FDI A;  1P49 A;  1F32 A;  3LXQ A;  4XB0 A;  4NKB A;  1A87 A;  4RCP A;  4J7B B;  4HAB A;  5AJ9 A;  4YYP A;  4H5X A;  4H71 A;  4N7V A;  4NK7 A;  1Q4O A;  3ED4 A;  1E2S P;  3Q1I A;  4N9J A;  4O56 A;  3KDR A;  2E50 A;  4O6W A;  2IA9 A;  4RS6 A;  3HFD A;  4DFW A;  1HDH A;  1E2T A;  1E1Z P;  1Q4K A;  3LM3 A;  5J19 A;  2I9Z A;  3P34 A;  4X9V A;  2UV8 G;  5DAY A;  4WHL A;  4G7N A;  3P2W A;  3GYV A;  3GYW A;  2QZU A;  4HCO A;  4E9C A;  1FSU A;  4O9W A;  4WHK A;  4CXU A;  4LKL A;  3BZI A;  3FS3 A;  5LHZ A;  1N2L A;  3P37 A;  3P36 A;  2VKZ G;  4X9R A;  5DNJ A;  2N19 A;  4E9D A;  3HIK A;  4E67 A;  5DMS A;  3P35 A;  1AUK A;  3FVH A;  4CYS A;  4HY2 A;  1E3C P;  4WHH A;  1UMW A;  4CXK A;  1F34 B;  3HMJ G;  4CYR A;  4CXS A;  3P2Z A;  4X9W A;  3HIH A;  1E33 P;  2I9X A;  3RQ7 A;  4FDJ A;  2OJX A;  4N7Z A;  5DMV C;  4LKM A;  2OGQ A;  1N2K A;  3C5L A; 
#chains in the Genus database with same CATH homology
 4WHK A;  4LKL A;  3BZI A;  4O6W A;  4RS6 A;  4HY2 A;  5LHZ A;  4DFW A;  4WHH A;  3P37 A;  3P36 A;  4XB0 A;  1UMW A;  1Q4K A;  5J19 A;  4X9R A;  4O9W A;  4RCP A;  4J7B B;  4HAB A;  3P34 A;  4O56 A;  4X9V A;  5DNJ A;  2N19 A;  4E9D A;  3P2Z A;  4WHL A;  3HIK A;  4X9W A;  3P2W A;  4E67 A;  3HIH A;  4YYP A;  4H5X A;  4HCO A;  3RQ7 A;  4H71 A;  5DMS A;  2OJX A;  5DMV C;  3P35 A;  4LKM A;  4E9C A;  2OGQ A;  1Q4O A;  3Q1I A;  3FVH A;  3C5L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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