3BZIA

Molecular and structural basis of polo-like kinase 1 substrate recognition: implications in centrosomal localization
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
223
structure length
223
Chain Sequence
DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 73
structure length 223
sequence length 223
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2008-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3bziA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3bziA01
2OJXA 4O6WA 4RCPA 4WHLA 5J19A 4XB0A 2N19A 3HIHA 4O9WA 4J7BB 4E9DA 3P2WA 3BZIA 3FVHA 5DMVC 5DMSA 1UMWA 1Q4OA 3C5LA 3Q1IA 4X9VA 4LKMA 2OGQA 3HIKA 3RQ7A 4RS6A 1Q4KA 4WHKA 4X9RA 4E67A 3P36A 4H5XA 3P34A 4HABA 3P37A 4O56A 4X9WA 4HY2A 4WHHA 3P2ZA 5DNJA 3P35A 4E9CA 4LKLA 4YYPA 4HCOA 5LHZA 4H71A 4DFWA
chains in the Genus database with same CATH superfamily
5DAYA 4RCPA 4E9DA 4NKBA 4N7ZA 4N7VA 4G7NA 1E33P 1Q4OA 3C5LA 4CYRA 1AUKA 2I9XA 3HIKA 4X9RA 4N9JA 4E67A 2E50A 3FS3A 4YYPA 4CXSA 1E3CP 2OJXA 5J19A 4CYSA 4O9WA 4J7BB 3P2WA 2IA9A 1N2LA 3GYVA 5DMSA 2VKZG 1F32A 1F34B 3HFDA 4WHKA 1A87A 4NK7A 3P34A 3P37A 4O56A 4CXKA 1FSUA 4X9WA 4HY2A 1P49A 4FDIA 4E9CA 2QZUA 4XB0A 2N19A 3LM3A 3ED4A 3GYWA 2I9ZA 4FDJA 3FVHA 4LKMA 2UV8G 3LXQA 1E2TA 3KDRA 4RS6A 1Q4KA 4CXUA 1N2KA 4WHHA 3P2ZA 5LHZA 4O6WA 4WHLA 1HDHA 3HIHA 3HMJG 3BZIA 5DMVC 1UMWA 3Q1IA 4X9VA 2OGQA 3RQ7A 1E1ZP 3P36A 4H5XA 4HABA 5AJ9A 5DNJA 3P35A 1E2SP 4LKLA 4HCOA 4H71A 4DFWA
chains in the Genus database with same CATH topology
2OJXA 4O6WA 4RCPA 4WHLA 5J19A 4XB0A 2N19A 3HIHA 4O9WA 4J7BB 4E9DA 3P2WA 3BZIA 3FVHA 5DMVC 5DMSA 1UMWA 1Q4OA 3C5LA 3Q1IA 4X9VA 4LKMA 2OGQA 3HIKA 3RQ7A 4RS6A 1Q4KA 4WHKA 4X9RA 4E67A 3P36A 4H5XA 3P34A 4HABA 3P37A 4O56A 4X9WA 4HY2A 4WHHA 3P2ZA 5DNJA 3P35A 4E9CA 4LKLA 4YYPA 4HCOA 5LHZA 4H71A 4DFWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OJX A;  4O6W A;  4RCP A;  4WHL A;  5J19 A;  4XB0 A;  2N19 A;  3HIH A;  4O9W A;  4J7B B;  4E9D A;  3P2W A;  3BZI A;  3FVH A;  5DMV C;  5DMS A;  1UMW A;  1Q4O A;  3C5L A;  3Q1I A;  4X9V A;  4LKM A;  2OGQ A;  3HIK A;  3RQ7 A;  4RS6 A;  1Q4K A;  4WHK A;  4X9R A;  4E67 A;  3P36 A;  4H5X A;  3P34 A;  4HAB A;  3P37 A;  4O56 A;  4X9W A;  4HY2 A;  4WHH A;  3P2Z A;  5DNJ A;  3P35 A;  4E9C A;  4LKL A;  4YYP A;  4HCO A;  5LHZ A;  4H71 A;  4DFW A; 
#chains in the Genus database with same CATH topology
 5DAY A;  4RCP A;  4E9D A;  4NKB A;  4N7Z A;  4N7V A;  4G7N A;  1E33 P;  1Q4O A;  3C5L A;  4CYR A;  1AUK A;  2I9X A;  3HIK A;  4X9R A;  4N9J A;  4E67 A;  2E50 A;  3FS3 A;  4YYP A;  4CXS A;  1E3C P;  2OJX A;  5J19 A;  4CYS A;  4O9W A;  4J7B B;  3P2W A;  2IA9 A;  1N2L A;  3GYV A;  5DMS A;  2VKZ G;  1F32 A;  1F34 B;  3HFD A;  4WHK A;  1A87 A;  4NK7 A;  3P34 A;  3P37 A;  4O56 A;  4CXK A;  1FSU A;  4X9W A;  4HY2 A;  1P49 A;  4FDI A;  4E9C A;  2QZU A;  4XB0 A;  2N19 A;  3LM3 A;  3ED4 A;  3GYW A;  2I9Z A;  4FDJ A;  3FVH A;  4LKM A;  2UV8 G;  3LXQ A;  1E2T A;  3KDR A;  4RS6 A;  1Q4K A;  4CXU A;  1N2K A;  4WHH A;  3P2Z A;  5LHZ A;  4O6W A;  4WHL A;  1HDH A;  3HIH A;  3HMJ G;  3BZI A;  5DMV C;  1UMW A;  3Q1I A;  4X9V A;  2OGQ A;  3RQ7 A;  1E1Z P;  3P36 A;  4H5X A;  4HAB A;  5AJ9 A;  5DNJ A;  3P35 A;  1E2S P;  4LKL A;  4HCO A;  4H71 A;  4DFW A; 
#chains in the Genus database with same CATH homology
 2OJX A;  4O6W A;  4RCP A;  4WHL A;  5J19 A;  4XB0 A;  2N19 A;  3HIH A;  4O9W A;  4J7B B;  4E9D A;  3P2W A;  3BZI A;  3FVH A;  5DMV C;  5DMS A;  1UMW A;  1Q4O A;  3C5L A;  3Q1I A;  4X9V A;  4LKM A;  2OGQ A;  3HIK A;  3RQ7 A;  4RS6 A;  1Q4K A;  4WHK A;  4X9R A;  4E67 A;  3P36 A;  4H5X A;  3P34 A;  4HAB A;  3P37 A;  4O56 A;  4X9W A;  4HY2 A;  4WHH A;  3P2Z A;  5DNJ A;  3P35 A;  4E9C A;  4LKL A;  4YYP A;  4HCO A;  5LHZ A;  4H71 A;  4DFW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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