3BZIA

Molecular and structural basis of polo-like kinase 1 substrate recognition: implications in centrosomal localization
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
223
structure length
223
Chain Sequence
DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Serine/threonine-protein kinase PLK1
publication title Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
pubmed doi rcsb
source organism Homo sapiens
total genus 73
structure length 223
sequence length 223
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2008-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3bziA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3bziA01
5J19A 4X9VA 3P35A 4WHLA 3BZIA 4RCPA 5DNJA 5DMVC 3FVHA 3RQ7A 4XB0A 3P34A 4E9DA 4O6WA 4X9RA 4DFWA 4WHKA 5DMSA 4WHHA 4O9WA 4O56A 4E67A 4H71A 1Q4KA 4HABA 4LKLA 4E9CA 2OJXA 3Q1IA 2OGQA 4HY2A 3P36A 4J7BB 3P2WA 1UMWA 1Q4OA 4RS6A 3P37A 5LHZA 3HIHA 3C5LA 4H5XA 4YYPA 2N19A 4LKMA 3HIKA 4HCOA 4X9WA 3P2ZA
chains in the Genus database with same CATH superfamily
1FSUA 1N2LA 4X9VA 3HFDA 4N7ZA 4WHLA 5DNJA 3FVHA 4E9DA 3P34A 4CYSA 4DFWA 3LXQA 5DMSA 4E9CA 3Q1IA 3P2WA 4N7VA 1HDHA 1N2KA 5AJ9A 4H5XA 5LHZA 3ED4A 2I9XA 3BZIA 4RCPA 3FS3A 4XB0A 4O6WA 3KDRA 1F34B 5DAYA 2QZUA 4WHKA 4WHHA 4FDIA 4HABA 2OGQA 2E50A 3P36A 4J7BB 4CXUA 4RS6A 3GYWA 3P37A 4YYPA 3LM3A 5DMVC 3GYVA 2UV8G 3RQ7A 3HMJG 1AUKA 4O56A 4E67A 4H71A 1Q4KA 2OJXA 4HY2A 1Q4OA 3C5LA 4LKMA 4NK7A 4CYRA 4X9WA 4NKBA 5J19A 3P35A 2IA9A 4CXSA 4G7NA 4FDJA 4CXKA 4X9RA 1E3CP 4O9WA 4LKLA 1E2TA 1F32A 1E33P 1E1ZP 1UMWA 2VKZG 4N9JA 3HIHA 1E2SP 2N19A 2I9ZA 1A87A 1P49A 3HIKA 4HCOA 3P2ZA
chains in the Genus database with same CATH topology
5J19A 4X9VA 3P35A 4WHLA 3BZIA 4RCPA 5DNJA 5DMVC 3FVHA 3RQ7A 4XB0A 3P34A 4E9DA 4O6WA 4X9RA 4DFWA 4WHKA 5DMSA 4WHHA 4O9WA 4O56A 4E67A 4H71A 1Q4KA 4HABA 4LKLA 4E9CA 2OJXA 3Q1IA 2OGQA 4HY2A 3P36A 4J7BB 3P2WA 1UMWA 1Q4OA 4RS6A 3P37A 5LHZA 3HIHA 3C5LA 4H5XA 4YYPA 2N19A 4LKMA 3HIKA 4HCOA 4X9WA 3P2ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J19 A;  4X9V A;  3P35 A;  4WHL A;  3BZI A;  4RCP A;  5DNJ A;  5DMV C;  3FVH A;  3RQ7 A;  4XB0 A;  3P34 A;  4E9D A;  4O6W A;  4X9R A;  4DFW A;  4WHK A;  5DMS A;  4WHH A;  4O9W A;  4O56 A;  4E67 A;  4H71 A;  1Q4K A;  4HAB A;  4LKL A;  4E9C A;  2OJX A;  3Q1I A;  2OGQ A;  4HY2 A;  3P36 A;  4J7B B;  3P2W A;  1UMW A;  1Q4O A;  4RS6 A;  3P37 A;  5LHZ A;  3HIH A;  3C5L A;  4H5X A;  4YYP A;  2N19 A;  4LKM A;  3HIK A;  4HCO A;  4X9W A;  3P2Z A; 
#chains in the Genus database with same CATH topology
 1FSU A;  1N2L A;  4X9V A;  3HFD A;  4N7Z A;  4WHL A;  5DNJ A;  3FVH A;  4E9D A;  3P34 A;  4CYS A;  4DFW A;  3LXQ A;  5DMS A;  4E9C A;  3Q1I A;  3P2W A;  4N7V A;  1HDH A;  1N2K A;  5AJ9 A;  4H5X A;  5LHZ A;  3ED4 A;  2I9X A;  3BZI A;  4RCP A;  3FS3 A;  4XB0 A;  4O6W A;  3KDR A;  1F34 B;  5DAY A;  2QZU A;  4WHK A;  4WHH A;  4FDI A;  4HAB A;  2OGQ A;  2E50 A;  3P36 A;  4J7B B;  4CXU A;  4RS6 A;  3GYW A;  3P37 A;  4YYP A;  3LM3 A;  5DMV C;  3GYV A;  2UV8 G;  3RQ7 A;  3HMJ G;  1AUK A;  4O56 A;  4E67 A;  4H71 A;  1Q4K A;  2OJX A;  4HY2 A;  1Q4O A;  3C5L A;  4LKM A;  4NK7 A;  4CYR A;  4X9W A;  4NKB A;  5J19 A;  3P35 A;  2IA9 A;  4CXS A;  4G7N A;  4FDJ A;  4CXK A;  4X9R A;  1E3C P;  4O9W A;  4LKL A;  1E2T A;  1F32 A;  1E33 P;  1E1Z P;  1UMW A;  2VKZ G;  4N9J A;  3HIH A;  1E2S P;  2N19 A;  2I9Z A;  1A87 A;  1P49 A;  3HIK A;  4HCO A;  3P2Z A; 
#chains in the Genus database with same CATH homology
 5J19 A;  4X9V A;  3P35 A;  4WHL A;  3BZI A;  4RCP A;  5DNJ A;  5DMV C;  3FVH A;  3RQ7 A;  4XB0 A;  3P34 A;  4E9D A;  4O6W A;  4X9R A;  4DFW A;  4WHK A;  5DMS A;  4WHH A;  4O9W A;  4O56 A;  4E67 A;  4H71 A;  1Q4K A;  4HAB A;  4LKL A;  4E9C A;  2OJX A;  3Q1I A;  2OGQ A;  4HY2 A;  3P36 A;  4J7B B;  3P2W A;  1UMW A;  1Q4O A;  4RS6 A;  3P37 A;  5LHZ A;  3HIH A;  3C5L A;  4H5X A;  4YYP A;  2N19 A;  4LKM A;  3HIK A;  4HCO A;  4X9W A;  3P2Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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