3P37A

Polo-like kinase i polo-box domain in complex with fdpplhspta phosphopeptide from pbip1
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
224
structure length
224
Chain Sequence
b'DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 70
structure length 224
sequence length 224
chains with identical sequence B, C
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p37A02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p37A01
3P2WA 4X9WA 4H5XA 4XB0A 4E67A 4WHKA 3P34A 3Q1IA 4HABA 4LKMA 1UMWA 4H71A 4WHLA 5DNJA 4O56A 1Q4KA 4HCOA 5LHZA 4DFWA 3HIHA 4WHHA 4RS6A 3BZIA 3P2ZA 4J7BB 4X9RA 4E9DA 2OGQA 5DMSA 3P36A 2OJXA 4HY2A 4LKLA 3RQ7A 4RCPA 2N19A 5DMVC 4X9VA 4YYPA 5J19A 1Q4OA 3FVHA 3P37A 3HIKA 4O6WA 3P35A 4E9CA 3C5LA 4O9WA
chains in the Genus database with same CATH superfamily
4X9WA 4CXSA 3HMJG 4N9JA 1Q4KA 4NK7A 4J7BB 2OGQA 4HY2A 3LXQA 3P37A 4FDIA 3C5LA 1AUKA 2UV8G 4XB0A 4WHKA 1A87A 4CYRA 4CYSA 3Q1IA 1E2TA 4H71A 4WHLA 5DNJA 1F32A 2I9XA 1N2KA 3KDRA 4O56A 4HCOA 5LHZA 1P49A 3HIHA 3BZIA 4X9RA 4FDJA 4LKLA 2N19A 1Q4OA 5DAYA 4O9WA 4E67A 4H5XA 3HFDA 3P34A 4NKBA 4WHHA 4CXKA 4RS6A 3P2ZA 3GYWA 4E9DA 4G7NA 3P36A 3RQ7A 2QZUA 1E1ZP 1FSUA 3ED4A 3FVHA 4CXUA 4O6WA 4E9CA 1E3CP 4N7VA 3P2WA 3GYVA 2VKZG 4HABA 1N2LA 4LKMA 1UMWA 1E33P 1E2SP 4DFWA 1HDHA 5DMSA 2OJXA 4RCPA 5DMVC 4X9VA 4YYPA 3LM3A 2E50A 2I9ZA 5J19A 5AJ9A 2IA9A 3FS3A 3HIKA 3P35A 1F34B 4N7ZA
chains in the Genus database with same CATH topology
3P2WA 4X9WA 4H5XA 4XB0A 4E67A 4WHKA 3P34A 3Q1IA 4HABA 4LKMA 1UMWA 4H71A 4WHLA 5DNJA 4O56A 1Q4KA 4HCOA 5LHZA 4DFWA 3HIHA 4WHHA 4RS6A 3BZIA 3P2ZA 4J7BB 4X9RA 4E9DA 2OGQA 5DMSA 3P36A 2OJXA 4HY2A 4LKLA 3RQ7A 4RCPA 2N19A 5DMVC 4X9VA 4YYPA 5J19A 1Q4OA 3FVHA 3P37A 3HIKA 4O6WA 3P35A 4E9CA 3C5LA 4O9WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P2W A;  4X9W A;  4H5X A;  4XB0 A;  4E67 A;  4WHK A;  3P34 A;  3Q1I A;  4HAB A;  4LKM A;  1UMW A;  4H71 A;  4WHL A;  5DNJ A;  4O56 A;  1Q4K A;  4HCO A;  5LHZ A;  4DFW A;  3HIH A;  4WHH A;  4RS6 A;  3BZI A;  3P2Z A;  4J7B B;  4X9R A;  4E9D A;  2OGQ A;  5DMS A;  3P36 A;  2OJX A;  4HY2 A;  4LKL A;  3RQ7 A;  4RCP A;  2N19 A;  5DMV C;  4X9V A;  4YYP A;  5J19 A;  1Q4O A;  3FVH A;  3P37 A;  3HIK A;  4O6W A;  3P35 A;  4E9C A;  3C5L A;  4O9W A; 
#chains in the Genus database with same CATH topology
 4X9W A;  4CXS A;  3HMJ G;  4N9J A;  1Q4K A;  4NK7 A;  4J7B B;  2OGQ A;  4HY2 A;  3LXQ A;  3P37 A;  4FDI A;  3C5L A;  1AUK A;  2UV8 G;  4XB0 A;  4WHK A;  1A87 A;  4CYR A;  4CYS A;  3Q1I A;  1E2T A;  4H71 A;  4WHL A;  5DNJ A;  1F32 A;  2I9X A;  1N2K A;  3KDR A;  4O56 A;  4HCO A;  5LHZ A;  1P49 A;  3HIH A;  3BZI A;  4X9R A;  4FDJ A;  4LKL A;  2N19 A;  1Q4O A;  5DAY A;  4O9W A;  4E67 A;  4H5X A;  3HFD A;  3P34 A;  4NKB A;  4WHH A;  4CXK A;  4RS6 A;  3P2Z A;  3GYW A;  4E9D A;  4G7N A;  3P36 A;  3RQ7 A;  2QZU A;  1E1Z P;  1FSU A;  3ED4 A;  3FVH A;  4CXU A;  4O6W A;  4E9C A;  1E3C P;  4N7V A;  3P2W A;  3GYV A;  2VKZ G;  4HAB A;  1N2L A;  4LKM A;  1UMW A;  1E33 P;  1E2S P;  4DFW A;  1HDH A;  5DMS A;  2OJX A;  4RCP A;  5DMV C;  4X9V A;  4YYP A;  3LM3 A;  2E50 A;  2I9Z A;  5J19 A;  5AJ9 A;  2IA9 A;  3FS3 A;  3HIK A;  3P35 A;  1F34 B;  4N7Z A; 
#chains in the Genus database with same CATH homology
 3P2W A;  4X9W A;  4H5X A;  4XB0 A;  4E67 A;  4WHK A;  3P34 A;  3Q1I A;  4HAB A;  4LKM A;  1UMW A;  4H71 A;  4WHL A;  5DNJ A;  4O56 A;  1Q4K A;  4HCO A;  5LHZ A;  4DFW A;  3HIH A;  4WHH A;  4RS6 A;  3BZI A;  3P2Z A;  4J7B B;  4X9R A;  4E9D A;  2OGQ A;  5DMS A;  3P36 A;  2OJX A;  4HY2 A;  4LKL A;  3RQ7 A;  4RCP A;  2N19 A;  5DMV C;  4X9V A;  4YYP A;  5J19 A;  1Q4O A;  3FVH A;  3P37 A;  3HIK A;  4O6W A;  3P35 A;  4E9C A;  3C5L A;  4O9W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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