3P37A

Polo-like kinase i polo-box domain in complex with fdpplhspta phosphopeptide from pbip1
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
224
structure length
224
Chain Sequence
DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 70
structure length 224
sequence length 224
chains with identical sequence B, C
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p37A02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p37A01
2OGQA 3HIHA 3FVHA 5DMVC 4RS6A 3C5LA 4H71A 4HCOA 4X9VA 3P34A 4E67A 5J19A 4RCPA 3RQ7A 4H5XA 1UMWA 2OJXA 4O6WA 5LHZA 4YYPA 4E9DA 4LKMA 4X9RA 3P35A 1Q4OA 4O56A 4E9CA 4HABA 4WHHA 3HIKA 4LKLA 4XB0A 5DMSA 4DFWA 3P2WA 3P36A 3P2ZA 4WHKA 1Q4KA 4J7BB 3P37A 4WHLA 4O9WA 2N19A 4HY2A 3BZIA 5DNJA 4X9WA 3Q1IA
chains in the Genus database with same CATH superfamily
3HIHA 3FVHA 3HFDA 4RS6A 4E67A 5LHZA 4O6WA 2UV8G 4N7VA 4X9RA 4O56A 4HABA 4N7ZA 4G7NA 4LKLA 5DMSA 3LXQA 1HDHA 3HMJG 2E50A 3P37A 4NKBA 1E3CP 4CXSA 1P49A 5DMVC 3C5LA 1N2LA 4HCOA 4CXKA 2OJXA 4CXUA 4E9DA 3P35A 3LM3A 1AUKA 4FDJA 3P36A 3P2ZA 1Q4KA 4J7BB 1E1ZP 2I9XA 3FS3A 4HY2A 3BZIA 5DNJA 1A87A 4CYRA 2OGQA 3GYVA 2VKZG 4CYSA 2I9ZA 5J19A 4RCPA 3KDRA 3RQ7A 4H5XA 1UMWA 1F32A 1E33P 3GYWA 2QZUA 4WHHA 1N2KA 5AJ9A 1F34B 3P2WA 4O9WA 1FSUA 5DAYA 4X9WA 2N19A 4NK7A 4H71A 4X9VA 3P34A 4LKMA 4YYPA 4N9JA 1Q4OA 3ED4A 4E9CA 3HIKA 4FDIA 4XB0A 4DFWA 1E2TA 4WHKA 2IA9A 4WHLA 3Q1IA 1E2SP
chains in the Genus database with same CATH topology
2OGQA 3HIHA 3FVHA 5DMVC 4RS6A 3C5LA 4H71A 4HCOA 4X9VA 3P34A 4E67A 5J19A 4RCPA 3RQ7A 4H5XA 1UMWA 2OJXA 4O6WA 5LHZA 4YYPA 4E9DA 4LKMA 4X9RA 3P35A 1Q4OA 4O56A 4E9CA 4HABA 4WHHA 3HIKA 4LKLA 4XB0A 5DMSA 4DFWA 3P2WA 3P36A 3P2ZA 4WHKA 1Q4KA 4J7BB 3P37A 4WHLA 4O9WA 2N19A 4HY2A 3BZIA 5DNJA 4X9WA 3Q1IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OGQ A;  3HIH A;  3FVH A;  5DMV C;  4RS6 A;  3C5L A;  4H71 A;  4HCO A;  4X9V A;  3P34 A;  4E67 A;  5J19 A;  4RCP A;  3RQ7 A;  4H5X A;  1UMW A;  2OJX A;  4O6W A;  5LHZ A;  4YYP A;  4E9D A;  4LKM A;  4X9R A;  3P35 A;  1Q4O A;  4O56 A;  4E9C A;  4HAB A;  4WHH A;  3HIK A;  4LKL A;  4XB0 A;  5DMS A;  4DFW A;  3P2W A;  3P36 A;  3P2Z A;  4WHK A;  1Q4K A;  4J7B B;  3P37 A;  4WHL A;  4O9W A;  2N19 A;  4HY2 A;  3BZI A;  5DNJ A;  4X9W A;  3Q1I A; 
#chains in the Genus database with same CATH topology
 3HIH A;  3FVH A;  3HFD A;  4RS6 A;  4E67 A;  5LHZ A;  4O6W A;  2UV8 G;  4N7V A;  4X9R A;  4O56 A;  4HAB A;  4N7Z A;  4G7N A;  4LKL A;  5DMS A;  3LXQ A;  1HDH A;  3HMJ G;  2E50 A;  3P37 A;  4NKB A;  1E3C P;  4CXS A;  1P49 A;  5DMV C;  3C5L A;  1N2L A;  4HCO A;  4CXK A;  2OJX A;  4CXU A;  4E9D A;  3P35 A;  3LM3 A;  1AUK A;  4FDJ A;  3P36 A;  3P2Z A;  1Q4K A;  4J7B B;  1E1Z P;  2I9X A;  3FS3 A;  4HY2 A;  3BZI A;  5DNJ A;  1A87 A;  4CYR A;  2OGQ A;  3GYV A;  2VKZ G;  4CYS A;  2I9Z A;  5J19 A;  4RCP A;  3KDR A;  3RQ7 A;  4H5X A;  1UMW A;  1F32 A;  1E33 P;  3GYW A;  2QZU A;  4WHH A;  1N2K A;  5AJ9 A;  1F34 B;  3P2W A;  4O9W A;  1FSU A;  5DAY A;  4X9W A;  2N19 A;  4NK7 A;  4H71 A;  4X9V A;  3P34 A;  4LKM A;  4YYP A;  4N9J A;  1Q4O A;  3ED4 A;  4E9C A;  3HIK A;  4FDI A;  4XB0 A;  4DFW A;  1E2T A;  4WHK A;  2IA9 A;  4WHL A;  3Q1I A;  1E2S P; 
#chains in the Genus database with same CATH homology
 2OGQ A;  3HIH A;  3FVH A;  5DMV C;  4RS6 A;  3C5L A;  4H71 A;  4HCO A;  4X9V A;  3P34 A;  4E67 A;  5J19 A;  4RCP A;  3RQ7 A;  4H5X A;  1UMW A;  2OJX A;  4O6W A;  5LHZ A;  4YYP A;  4E9D A;  4LKM A;  4X9R A;  3P35 A;  1Q4O A;  4O56 A;  4E9C A;  4HAB A;  4WHH A;  3HIK A;  4LKL A;  4XB0 A;  5DMS A;  4DFW A;  3P2W A;  3P36 A;  3P2Z A;  4WHK A;  1Q4K A;  4J7B B;  3P37 A;  4WHL A;  4O9W A;  2N19 A;  4HY2 A;  3BZI A;  5DNJ A;  4X9W A;  3Q1I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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