The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
56
|
sequence length |
218
|
structure length |
218
|
Chain Sequence |
SHMDRISVPPLNTKRLLPTRYKTKNAIMSILRNGEVVLEFLKFRPTYNEDRINDICRISDDGQRIIIYQPDPGRGLPVREQPPDLQIPSGDCVYNYDNLPSKHWKKYIYGARFVGLVKSKTPKVTYFSTLGKCQLMETMTDFEIRFYSGAKLLKTPSEGLKVYDRNGMLLSDYSCSESRSLIEHGNECFTHCVNISNALEVAQTKDNSCFPVTIGRRP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The structure of the plk4 cryptic polo box reveals two tandem polo boxes required for centriole duplication.
pubmed doi rcsb |
| molecule tags |
Transferase
|
| source organism |
Drosophila melanogaster
|
| molecule keywords |
Serine/threonine-protein kinase PLK4
|
| total genus |
56
|
| structure length |
218
|
| sequence length |
218
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.7.11.21: Polo kinase. |
| pdb deposition date | 2012-07-20 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF18190 | Plk4_PB1 | Polo-like Kinase 4 Polo Box 1 |
| A | PF18409 | Plk4_PB2 | Polo-like Kinase 4 Polo Box 2 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Arylsulfatase, C-terminal domain | Arylsulfatase, C-terminal domain | ||
| Alpha Beta | 2-Layer Sandwich | Arylsulfatase, C-terminal domain | Arylsulfatase, C-terminal domain |
#chains in the Genus database with same CATH superfamily 4NK7 A; 4N9J A; 4N7Z A; 4G7N A; 4NKB A; 4N7V A; #chains in the Genus database with same CATH topology 4NK7 A; 4WHL A; 2I9X A; 1UMW A; 4WHK A; 1F32 A; 2QZU A; 2VKZ G; 4CYS A; 3HIH A; 3LXQ A; 4FDI A; 2OJX A; 4CXK A; 4YYP A; 1E3C P; 3P35 A; 2IA9 A; 4X9W A; 1E1Z P; 4CXS A; 4X9V A; 4RCP A; 1N2L A; 5DAY A; 3FVH A; 3FS3 A; 4J7B B; 4E9C A; 1A87 A; 1HDH A; 4WHH A; 4O9W A; 4HAB A; 3KDR A; 3Q1I A; 2I9Z A; 4XB0 A; 5DMV C; 4LKL A; 3HMJ G; 1FSU A; 1N2K A; 3P36 A; 4DFW A; 5AJ9 A; 3P2W A; 1Q4O A; 4E67 A; 3RQ7 A; 5DMS A; 3C5L A; 4O56 A; 4HCO A; 4G7N A; 1E2S P; 1F34 B; 4NKB A; 5J19 A; 4E9D A; 2UV8 G; 1AUK A; 1P49 A; 3GYW A; 1Q4K A; 3P2Z A; 4H71 A; 5LHZ A; 4CYR A; 2N19 A; 4HY2 A; 3HIK A; 3LM3 A; 4N9J A; 1E33 P; 4LKM A; 1E2T A; 3BZI A; 5DNJ A; 4X9R A; 4N7Z A; 3P34 A; 2E50 A; 4O6W A; 4N7V A; 4RS6 A; 3ED4 A; 4H5X A; 3P37 A; 4CXU A; 4FDJ A; 3GYV A; 3HFD A; 2OGQ A; #chains in the Genus database with same CATH homology 1HDH A; 4NK7 A; 3KDR A; 2QZU A; 2VKZ G; 4CYR A; 4CYS A; 3LXQ A; 4FDI A; 4CXK A; 3LM3 A; 4N9J A; 1E33 P; 4G7N A; 1E3C P; 1E2S P; 1E2T A; 4NKB A; 3HMJ G; 1FSU A; 2UV8 G; 4N7Z A; 1AUK A; 1E1Z P; 4CXS A; 1N2K A; 2E50 A; 4N7V A; 1N2L A; 5DAY A; 1P49 A; 3FS3 A; 3GYW A; 3ED4 A; 5AJ9 A; 4FDJ A; 3GYV A; 4CXU A; 3HFD A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
