4XB0A

Structure of the plk2 polo-box domain
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
213
structure length
213
Chain Sequence
GSVADTVARVLRGCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTLLMSGCSSELKNRMEYALNMLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural analysis of the polo-box domain of human Polo-like kinase 2
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Serine/threonine-protein kinase PLK2
total genus 55
structure length 213
sequence length 213
chains with identical sequence B
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2014-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 4xb0A02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 4xb0A01
4HY2A 4X9WA 3P37A 3RQ7A 4H71A 1Q4OA 5DMSA 4E9CA 4RCPA 3C5LA 4DFWA 3P2ZA 3FVHA 3P35A 2OJXA 5DMVC 4WHHA 4X9VA 4E9DA 4X9RA 3BZIA 4O56A 1UMWA 4RS6A 5LHZA 4HABA 4E67A 3HIKA 3P34A 4O6WA 4O9WA 5J19A 4LKMA 4WHLA 4J7BB 2OGQA 4WHKA 1Q4KA 4YYPA 3HIHA 4XB0A 3P36A 2N19A 5DNJA 4LKLA 3P2WA 4H5XA 3Q1IA 4HCOA
chains in the Genus database with same CATH superfamily
4HY2A 4G7NA 3P37A 4NK7A 3RQ7A 4H71A 2IA9A 3LXQA 3C5LA 4DFWA 2VKZG 1P49A 3KDRA 4E9DA 1N2LA 4O6WA 4WHLA 2I9XA 4J7BB 4CXUA 4CXSA 5DAYA 3GYVA 3P36A 1E2SP 2N19A 3P2WA 1E1ZP 2I9ZA 1A87A 3HMJG 5DMSA 2OJXA 1E2TA 5AJ9A 4X9RA 3BZIA 1E3CP 1UMWA 4N7VA 4E67A 4O9WA 2E50A 1E33P 3HFDA 4YYPA 1N2KA 1AUKA 4NKBA 5DNJA 4LKLA 4HCOA 4X9WA 4CYSA 1HDHA 4FDIA 4FDJA 4E9CA 4N7ZA 4RCPA 3P2ZA 3P35A 5DMVC 3GYWA 4X9VA 1FSUA 4CYRA 4HABA 3P34A 4LKMA 3ED4A 4WHKA 1Q4KA 4XB0A 4N9JA 1F32A 1F34B 1Q4OA 3LM3A 4CXKA 3FS3A 3FVHA 4WHHA 4O56A 4RS6A 5LHZA 3HIKA 5J19A 2OGQA 3HIHA 2QZUA 2UV8G 4H5XA 3Q1IA
chains in the Genus database with same CATH topology
4HY2A 4X9WA 3P37A 3RQ7A 4H71A 1Q4OA 5DMSA 4E9CA 4RCPA 3C5LA 4DFWA 3P2ZA 3FVHA 3P35A 2OJXA 5DMVC 4WHHA 4X9VA 4E9DA 4X9RA 3BZIA 4O56A 1UMWA 4RS6A 5LHZA 4HABA 4E67A 3HIKA 3P34A 4O6WA 4O9WA 5J19A 4LKMA 4WHLA 4J7BB 2OGQA 4WHKA 1Q4KA 4YYPA 3HIHA 4XB0A 3P36A 2N19A 5DNJA 4LKLA 3P2WA 4H5XA 3Q1IA 4HCOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HY2 A;  4X9W A;  3P37 A;  3RQ7 A;  4H71 A;  1Q4O A;  5DMS A;  4E9C A;  4RCP A;  3C5L A;  4DFW A;  3P2Z A;  3FVH A;  3P35 A;  2OJX A;  5DMV C;  4WHH A;  4X9V A;  4E9D A;  4X9R A;  3BZI A;  4O56 A;  1UMW A;  4RS6 A;  5LHZ A;  4HAB A;  4E67 A;  3HIK A;  3P34 A;  4O6W A;  4O9W A;  5J19 A;  4LKM A;  4WHL A;  4J7B B;  2OGQ A;  4WHK A;  1Q4K A;  4YYP A;  3HIH A;  4XB0 A;  3P36 A;  2N19 A;  5DNJ A;  4LKL A;  3P2W A;  4H5X A;  3Q1I A;  4HCO A; 
#chains in the Genus database with same CATH topology
 4HY2 A;  4G7N A;  3P37 A;  4NK7 A;  3RQ7 A;  4H71 A;  2IA9 A;  3LXQ A;  3C5L A;  4DFW A;  2VKZ G;  1P49 A;  3KDR A;  4E9D A;  1N2L A;  4O6W A;  4WHL A;  2I9X A;  4J7B B;  4CXU A;  4CXS A;  5DAY A;  3GYV A;  3P36 A;  1E2S P;  2N19 A;  3P2W A;  1E1Z P;  2I9Z A;  1A87 A;  3HMJ G;  5DMS A;  2OJX A;  1E2T A;  5AJ9 A;  4X9R A;  3BZI A;  1E3C P;  1UMW A;  4N7V A;  4E67 A;  4O9W A;  2E50 A;  1E33 P;  3HFD A;  4YYP A;  1N2K A;  1AUK A;  4NKB A;  5DNJ A;  4LKL A;  4HCO A;  4X9W A;  4CYS A;  1HDH A;  4FDI A;  4FDJ A;  4E9C A;  4N7Z A;  4RCP A;  3P2Z A;  3P35 A;  5DMV C;  3GYW A;  4X9V A;  1FSU A;  4CYR A;  4HAB A;  3P34 A;  4LKM A;  3ED4 A;  4WHK A;  1Q4K A;  4XB0 A;  4N9J A;  1F32 A;  1F34 B;  1Q4O A;  3LM3 A;  4CXK A;  3FS3 A;  3FVH A;  4WHH A;  4O56 A;  4RS6 A;  5LHZ A;  3HIK A;  5J19 A;  2OGQ A;  3HIH A;  2QZU A;  2UV8 G;  4H5X A;  3Q1I A; 
#chains in the Genus database with same CATH homology
 4HY2 A;  4X9W A;  3P37 A;  3RQ7 A;  4H71 A;  1Q4O A;  5DMS A;  4E9C A;  4RCP A;  3C5L A;  4DFW A;  3P2Z A;  3FVH A;  3P35 A;  2OJX A;  5DMV C;  4WHH A;  4X9V A;  4E9D A;  4X9R A;  3BZI A;  4O56 A;  1UMW A;  4RS6 A;  5LHZ A;  4HAB A;  4E67 A;  3HIK A;  3P34 A;  4O6W A;  4O9W A;  5J19 A;  4LKM A;  4WHL A;  4J7B B;  2OGQ A;  4WHK A;  1Q4K A;  4YYP A;  3HIH A;  4XB0 A;  3P36 A;  2N19 A;  5DNJ A;  4LKL A;  3P2W A;  4H5X A;  3Q1I A;  4HCO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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