5LHZA

Pb3 domain of human plk4 in complex with coiled-coil domain of stil
Total Genus 18
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
78
structure length
78
Chain Sequence
QLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
pubmed doi rcsb
molecule keywords Serine/threonine-protein kinase PLK4
molecule tags Structural protein
source organism Homo sapiens
total genus 18
structure length 78
sequence length 78
chains with identical sequence B, C
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2016-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 5lhzA00
3P35A 5DMVC 4X9RA 3P2ZA 3P34A 3HIHA 3P37A 4O56A 2N19A 4X9VA 4YYPA 4HCOA 3RQ7A 4RS6A 4E9DA 5LHZA 4O9WA 4HABA 4X9WA 4LKLA 3C5LA 4H71A 4WHHA 4LKMA 2OGQA 3P2WA 3Q1IA 3HIKA 1Q4KA 4RCPA 2OJXA 3FVHA 4O6WA 4WHLA 5J19A 1Q4OA 3P36A 4H5XA 4DFWA 4WHKA 4E9CA 5DMSA 4J7BB 4XB0A 1UMWA 4E67A 5DNJA 4HY2A 3BZIA
chains in the Genus database with same CATH superfamily
5DAYA 2I9ZA 4X9RA 3P2ZA 4O56A 1HDHA 4NKBA 3RQ7A 4HABA 4WHHA 1Q4KA 3HIKA 4RCPA 4NK7A 2OJXA 3FVHA 1E33P 4WHLA 4N7VA 1Q4OA 4CXUA 4E9CA 5DMSA 3GYWA 4J7BB 1UMWA 3P35A 1E3CP 2E50A 3P34A 3HIHA 4N9JA 4E9DA 4RS6A 2I9XA 4LKLA 1F34B 4CYSA 4O6WA 1E1ZP 4CXSA 3P36A 4H5XA 1E2SP 4DFWA 3FS3A 3BZIA 4G7NA 5DMVC 1P49A 1A87A 3P37A 4CYRA 4X9VA 4O9WA 4CXKA 4FDJA 3C5LA 1F32A 2VKZG 3Q1IA 3LXQA 3KDRA 2QZUA 1AUKA 1E2TA 4XB0A 4E67A 4N7ZA 4HY2A 5DNJA 2UV8G 2IA9A 5AJ9A 2N19A 3LM3A 4YYPA 3ED4A 4HCOA 5LHZA 4X9WA 4H71A 4LKMA 2OGQA 1FSUA 3P2WA 3HFDA 1N2LA 3GYVA 3HMJG 5J19A 1N2KA 4WHKA 4FDIA
chains in the Genus database with same CATH topology
3P35A 5DMVC 4X9RA 3P2ZA 3P34A 3HIHA 3P37A 4O56A 2N19A 4X9VA 4YYPA 4HCOA 3RQ7A 4RS6A 4E9DA 5LHZA 4O9WA 4HABA 4X9WA 4LKLA 3C5LA 4H71A 4WHHA 4LKMA 2OGQA 3P2WA 3Q1IA 3HIKA 1Q4KA 4RCPA 2OJXA 3FVHA 4O6WA 4WHLA 5J19A 1Q4OA 3P36A 4H5XA 4DFWA 4WHKA 4E9CA 5DMSA 4J7BB 4XB0A 1UMWA 4E67A 5DNJA 4HY2A 3BZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P35 A;  5DMV C;  4X9R A;  3P2Z A;  3P34 A;  3HIH A;  3P37 A;  4O56 A;  2N19 A;  4X9V A;  4YYP A;  4HCO A;  3RQ7 A;  4RS6 A;  4E9D A;  5LHZ A;  4O9W A;  4HAB A;  4X9W A;  4LKL A;  3C5L A;  4H71 A;  4WHH A;  4LKM A;  2OGQ A;  3P2W A;  3Q1I A;  3HIK A;  1Q4K A;  4RCP A;  2OJX A;  3FVH A;  4O6W A;  4WHL A;  5J19 A;  1Q4O A;  3P36 A;  4H5X A;  4DFW A;  4WHK A;  4E9C A;  5DMS A;  4J7B B;  4XB0 A;  1UMW A;  4E67 A;  5DNJ A;  4HY2 A;  3BZI A; 
#chains in the Genus database with same CATH topology
 5DAY A;  2I9Z A;  4X9R A;  3P2Z A;  4O56 A;  1HDH A;  4NKB A;  3RQ7 A;  4HAB A;  4WHH A;  1Q4K A;  3HIK A;  4RCP A;  4NK7 A;  2OJX A;  3FVH A;  1E33 P;  4WHL A;  4N7V A;  1Q4O A;  4CXU A;  4E9C A;  5DMS A;  3GYW A;  4J7B B;  1UMW A;  3P35 A;  1E3C P;  2E50 A;  3P34 A;  3HIH A;  4N9J A;  4E9D A;  4RS6 A;  2I9X A;  4LKL A;  1F34 B;  4CYS A;  4O6W A;  1E1Z P;  4CXS A;  3P36 A;  4H5X A;  1E2S P;  4DFW A;  3FS3 A;  3BZI A;  4G7N A;  5DMV C;  1P49 A;  1A87 A;  3P37 A;  4CYR A;  4X9V A;  4O9W A;  4CXK A;  4FDJ A;  3C5L A;  1F32 A;  2VKZ G;  3Q1I A;  3LXQ A;  3KDR A;  2QZU A;  1AUK A;  1E2T A;  4XB0 A;  4E67 A;  4N7Z A;  4HY2 A;  5DNJ A;  2UV8 G;  2IA9 A;  5AJ9 A;  2N19 A;  3LM3 A;  4YYP A;  3ED4 A;  4HCO A;  5LHZ A;  4X9W A;  4H71 A;  4LKM A;  2OGQ A;  1FSU A;  3P2W A;  3HFD A;  1N2L A;  3GYV A;  3HMJ G;  5J19 A;  1N2K A;  4WHK A;  4FDI A; 
#chains in the Genus database with same CATH homology
 3P35 A;  5DMV C;  4X9R A;  3P2Z A;  3P34 A;  3HIH A;  3P37 A;  4O56 A;  2N19 A;  4X9V A;  4YYP A;  4HCO A;  3RQ7 A;  4RS6 A;  4E9D A;  5LHZ A;  4O9W A;  4HAB A;  4X9W A;  4LKL A;  3C5L A;  4H71 A;  4WHH A;  4LKM A;  2OGQ A;  3P2W A;  3Q1I A;  3HIK A;  1Q4K A;  4RCP A;  2OJX A;  3FVH A;  4O6W A;  4WHL A;  5J19 A;  1Q4O A;  3P36 A;  4H5X A;  4DFW A;  4WHK A;  4E9C A;  5DMS A;  4J7B B;  4XB0 A;  1UMW A;  4E67 A;  5DNJ A;  4HY2 A;  3BZI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...