2CAXA

Structural basis for cooperative binding of ribbon-helix-helix repressor omega to mutated direct dna heptad repeats
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
53
structure length
53
Chain Sequence
MAKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMDQALEEYIRKYLPDKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription.
pubmed doi rcsb
molecule tags Transcriptional repressor
source organism Streptococcus pyogenes
molecule keywords ORF OMEGA
total genus 15
structure length 53
sequence length 53
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2005-12-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1220.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant Met repressor-like 2caxA00
2K1OA 3H87C 3VEBA 4HV0A 2K29A 3VW4A 3GXQA 2JXGA 2K5JA 2WVEA 2CADA 4ME7E 1X93A 2BA3A 1BAZA 2CAJA 2K6LA 1B01A 2BSQE 1ARQA 1IRQA 2WVBA 2WVFA 2K9IA 1U9PA 2JXIA 3FT7A 1EA4A 2BNWA 2WVCA 1MNTA 4FXEA 3OD2A 2HZVA 1NLAA 2BJ7A 2RBFA 1BDTA 2KELA 2BJ9A 2H1OE 1Q5VA 2CA9A 2BJ1A 2GPEA 2WVDA 3QOQA 1BDVA 2CAXA 2BJ8A 1QTGA 1B28A 3LGHA 1PARA 1MYLA 2JXHA 4D8JA 1ARRA 2BNZA 3VEAA 2CPGA 1MYKA 1P94A 2BJ3A 2AY0A 3FMTA 2HZAA
chains in the Genus database with same CATH superfamily
3SFGA 1B01A 1OHNA 3NO7A 2JXIA 1EA4A 2BNWA 4O4RA 1BDTA 4AAIA 1Q5VA 2CA9A 2CAXA 4LQ9A 2BJ8A 3SFUA 1MYLA 3BSOA 2UUWA 3FMTA 3H87C 3VEBA 4HV0A 2ADLA 2WK4A 2K5JA 2JBVA 2H3AA 1BAZA 3H5YA 2K9IA 3QIDA 1SH3A 1NLAA 3NAHA 4MJWA 1Q16A 4QPXA 2H1OE 1BDVA 2AN7A 1QTGA 4NRTA 2JXHA 3UR0A 3VEAA 2CPGA 1SIWA 2KKEA 2AY0A 2K1OA 2UUTA 3H5XA 3VW4A 2JXGA 2WVEA 2CADA 4ME7E 1X93A 2K6LA 1ARQA 2BSQE 1IRQA 2WVBA 2WVFA 1U9PA 3OD2A 2HZVA 3G5OA 2RBFA 3UPFA 2WVDA 4LQ3A 2BNZA 4D8JA 1MYKA 1P94A 2CKWA 3UQSA 2HZAA 2A2BA 3BSNA 2K29A 3GXQA 1SH0A 3LJPA 1OG7A 2BA3A 2CAJA 3FT7A 4LRVA 2WVCA 2Q2KA 1MNTA 4FXEA 1SH2A 2KOEA 2BJ7A 3NAIA 2KELA 4NRUA 2BJ9A 3IR7A 2GPEA 2BJ1A 3QOQA 1B28A 2B43A 3LGHA 1PARA 1ARRA 3NNEA 2BJ3A
chains in the Genus database with same CATH topology
2K1OA 3H87C 3VEBA 4HV0A 2K29A 3VW4A 3GXQA 2JXGA 2K5JA 2WVEA 2CADA 4ME7E 1X93A 2BA3A 1BAZA 2CAJA 2K6LA 1B01A 2BSQE 1ARQA 1IRQA 2WVBA 2WVFA 2K9IA 1U9PA 2JXIA 3FT7A 1EA4A 2BNWA 2WVCA 1MNTA 4FXEA 3OD2A 2HZVA 1NLAA 2BJ7A 2RBFA 1BDTA 2KELA 2BJ9A 2H1OE 1Q5VA 2CA9A 2BJ1A 2GPEA 2WVDA 3QOQA 1BDVA 2CAXA 2BJ8A 1QTGA 1B28A 3LGHA 1PARA 1MYLA 2JXHA 4D8JA 1ARRA 2BNZA 3VEAA 2CPGA 1MYKA 1P94A 2BJ3A 2AY0A 3FMTA 2HZAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K1O A;  3H87 C;  3VEB A;  4HV0 A;  2K29 A;  3VW4 A;  3GXQ A;  2JXG A;  2K5J A;  2WVE A;  2CAD A;  4ME7 E;  1X93 A;  2BA3 A;  1BAZ A;  2CAJ A;  2K6L A;  1B01 A;  2BSQ E;  1ARQ A;  1IRQ A;  2WVB A;  2WVF A;  2K9I A;  1U9P A;  2JXI A;  3FT7 A;  1EA4 A;  2BNW A;  2WVC A;  1MNT A;  4FXE A;  3OD2 A;  2HZV A;  1NLA A;  2BJ7 A;  2RBF A;  1BDT A;  2KEL A;  2BJ9 A;  2H1O E;  1Q5V A;  2CA9 A;  2BJ1 A;  2GPE A;  2WVD A;  3QOQ A;  1BDV A;  2CAX A;  2BJ8 A;  1QTG A;  1B28 A;  3LGH A;  1PAR A;  1MYL A;  2JXH A;  4D8J A;  1ARR A;  2BNZ A;  3VEA A;  2CPG A;  1MYK A;  1P94 A;  2BJ3 A;  2AY0 A;  3FMT A;  2HZA A; 
#chains in the Genus database with same CATH topology
 3SFG A;  1B01 A;  1OHN A;  3NO7 A;  2JXI A;  1EA4 A;  2BNW A;  4O4R A;  1BDT A;  4AAI A;  1Q5V A;  2CA9 A;  2CAX A;  4LQ9 A;  2BJ8 A;  3SFU A;  1MYL A;  3BSO A;  2UUW A;  3FMT A;  3H87 C;  3VEB A;  4HV0 A;  2ADL A;  2WK4 A;  2K5J A;  2JBV A;  2H3A A;  1BAZ A;  3H5Y A;  2K9I A;  3QID A;  1SH3 A;  1NLA A;  3NAH A;  4MJW A;  1Q16 A;  4QPX A;  2H1O E;  1BDV A;  2AN7 A;  1QTG A;  4NRT A;  2JXH A;  3UR0 A;  3VEA A;  2CPG A;  1SIW A;  2KKE A;  2AY0 A;  2K1O A;  2UUT A;  3H5X A;  3VW4 A;  2JXG A;  2WVE A;  2CAD A;  4ME7 E;  1X93 A;  2K6L A;  1ARQ A;  2BSQ E;  1IRQ A;  2WVB A;  2WVF A;  1U9P A;  3OD2 A;  2HZV A;  3G5O A;  2RBF A;  3UPF A;  2WVD A;  4LQ3 A;  2BNZ A;  4D8J A;  1MYK A;  1P94 A;  2CKW A;  3UQS A;  2HZA A;  2A2B A;  3BSN A;  2K29 A;  3GXQ A;  1SH0 A;  3LJP A;  1OG7 A;  2BA3 A;  2CAJ A;  3FT7 A;  4LRV A;  2WVC A;  2Q2K A;  1MNT A;  4FXE A;  1SH2 A;  2KOE A;  2BJ7 A;  3NAI A;  2KEL A;  4NRU A;  2BJ9 A;  3IR7 A;  2GPE A;  2BJ1 A;  3QOQ A;  1B28 A;  2B43 A;  3LGH A;  1PAR A;  1ARR A;  3NNE A;  2BJ3 A; 
#chains in the Genus database with same CATH homology
 2K1O A;  3H87 C;  3VEB A;  4HV0 A;  2K29 A;  3VW4 A;  3GXQ A;  2JXG A;  2K5J A;  2WVE A;  2CAD A;  4ME7 E;  1X93 A;  2BA3 A;  1BAZ A;  2CAJ A;  2K6L A;  1B01 A;  2BSQ E;  1ARQ A;  1IRQ A;  2WVB A;  2WVF A;  2K9I A;  1U9P A;  2JXI A;  3FT7 A;  1EA4 A;  2BNW A;  2WVC A;  1MNT A;  4FXE A;  3OD2 A;  2HZV A;  1NLA A;  2BJ7 A;  2RBF A;  1BDT A;  2KEL A;  2BJ9 A;  2H1O E;  1Q5V A;  2CA9 A;  2BJ1 A;  2GPE A;  2WVD A;  3QOQ A;  1BDV A;  2CAX A;  2BJ8 A;  1QTG A;  1B28 A;  3LGH A;  1PAR A;  1MYL A;  2JXH A;  4D8J A;  1ARR A;  2BNZ A;  3VEA A;  2CPG A;  1MYK A;  1P94 A;  2BJ3 A;  2AY0 A;  3FMT A;  2HZA A; 
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similar chains in the Genus database (?% sequence similarity)
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