2CAXA

Structural basis for cooperative binding of ribbon-helix-helix repressor omega to mutated direct dna heptad repeats
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
53
structure length
53
Chain Sequence
MAKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMDQALEEYIRKYLPDKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription.
pubmed doi rcsb
molecule tags Transcriptional repressor
source organism Streptococcus pyogenes
molecule keywords ORF OMEGA
total genus 15
structure length 53
sequence length 53
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2005-12-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1220.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant Met repressor-like 2caxA00
3VEBA 2K1OA 1ARRA 2WVEA 3H87C 3OD2A 1PARA 2K9IA 4HV0A 2CAJA 2HZAA 2WVDA 1EA4A 2JXGA 2BSQE 2GPEA 2H1OE 1ARQA 2KELA 1X93A 3VEAA 2RBFA 1BAZA 2BNWA 3FMTA 4D8JA 3GXQA 2K6LA 1BDTA 2CPGA 2K29A 2JXIA 2BJ3A 2BA3A 1BDVA 1U9PA 2AY0A 1Q5VA 1MNTA 2JXHA 1QTGA 2WVBA 2BJ9A 2WVFA 2BJ7A 1IRQA 1P94A 2BJ8A 2CA9A 2HZVA 2BNZA 3QOQA 3VW4A 4FXEA 2CAXA 2WVCA 2K5JA 3FT7A 1B28A 1B01A 1MYKA 1NLAA 1MYLA 2CADA 2BJ1A 3LGHA 4ME7E
chains in the Genus database with same CATH superfamily
3H87C 2HZAA 2WVDA 3UQSA 1X93A 2A2BA 1BAZA 3H5YA 1OHNA 2BJ3A 2BA3A 1BDVA 2BJ9A 3H5XA 3G5OA 3NO7A 1P94A 4NRUA 3NAIA 2H3AA 4FXEA 3FT7A 1MYKA 2WK4A 4NRTA 2AN7A 3VEBA 3OD2A 1PARA 2CAJA 2BSQE 2H1OE 3VEAA 3UR0A 2K6LA 1SH0A 2CPGA 2K29A 3BSOA 4LQ9A 3UPFA 3IR7A 2JXHA 1SIWA 3SFUA 3VW4A 2UUWA 2WVCA 4QPXA 1B01A 2K1OA 1OG7A 4AAIA 2WVEA 4HV0A 1EA4A 1ARQA 2CKWA 2KELA 2KOEA 2B43A 2RBFA 2UUTA 2KKEA 3GXQA 4O4RA 1BDTA 2JBVA 1SH2A 1QTGA 2WVFA 2BJ7A 2BJ8A 3LJPA 2BNZA 3NNEA 3NAHA 2K5JA 1B28A 4MJWA 2CADA 1MYLA 2BJ1A 1ARRA 2K9IA 4LRVA 2JXGA 3BSNA 2GPEA 3SFGA 2BNWA 2ADLA 3FMTA 4D8JA 2JXIA 4LQ3A 1U9PA 1Q16A 2AY0A 1Q5VA 1MNTA 3QIDA 2Q2KA 2WVBA 1IRQA 2CA9A 2HZVA 3QOQA 2CAXA 1NLAA 1SH3A 3LGHA 4ME7E
chains in the Genus database with same CATH topology
3VEBA 2K1OA 1ARRA 2WVEA 3H87C 3OD2A 1PARA 2K9IA 4HV0A 2CAJA 2HZAA 2WVDA 1EA4A 2JXGA 2BSQE 2GPEA 2H1OE 1ARQA 2KELA 1X93A 3VEAA 2RBFA 1BAZA 2BNWA 3FMTA 4D8JA 3GXQA 2K6LA 1BDTA 2CPGA 2K29A 2JXIA 2BJ3A 2BA3A 1BDVA 1U9PA 2AY0A 1Q5VA 1MNTA 2JXHA 1QTGA 2WVBA 2BJ9A 2WVFA 2BJ7A 1IRQA 1P94A 2BJ8A 2CA9A 2HZVA 2BNZA 3QOQA 3VW4A 4FXEA 2CAXA 2WVCA 2K5JA 3FT7A 1B28A 1B01A 1MYKA 1NLAA 1MYLA 2CADA 2BJ1A 3LGHA 4ME7E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VEB A;  2K1O A;  1ARR A;  2WVE A;  3H87 C;  3OD2 A;  1PAR A;  2K9I A;  4HV0 A;  2CAJ A;  2HZA A;  2WVD A;  1EA4 A;  2JXG A;  2BSQ E;  2GPE A;  2H1O E;  1ARQ A;  2KEL A;  1X93 A;  3VEA A;  2RBF A;  1BAZ A;  2BNW A;  3FMT A;  4D8J A;  3GXQ A;  2K6L A;  1BDT A;  2CPG A;  2K29 A;  2JXI A;  2BJ3 A;  2BA3 A;  1BDV A;  1U9P A;  2AY0 A;  1Q5V A;  1MNT A;  2JXH A;  1QTG A;  2WVB A;  2BJ9 A;  2WVF A;  2BJ7 A;  1IRQ A;  1P94 A;  2BJ8 A;  2CA9 A;  2HZV A;  2BNZ A;  3QOQ A;  3VW4 A;  4FXE A;  2CAX A;  2WVC A;  2K5J A;  3FT7 A;  1B28 A;  1B01 A;  1MYK A;  1NLA A;  1MYL A;  2CAD A;  2BJ1 A;  3LGH A;  4ME7 E; 
#chains in the Genus database with same CATH topology
 3H87 C;  2HZA A;  2WVD A;  3UQS A;  1X93 A;  2A2B A;  1BAZ A;  3H5Y A;  1OHN A;  2BJ3 A;  2BA3 A;  1BDV A;  2BJ9 A;  3H5X A;  3G5O A;  3NO7 A;  1P94 A;  4NRU A;  3NAI A;  2H3A A;  4FXE A;  3FT7 A;  1MYK A;  2WK4 A;  4NRT A;  2AN7 A;  3VEB A;  3OD2 A;  1PAR A;  2CAJ A;  2BSQ E;  2H1O E;  3VEA A;  3UR0 A;  2K6L A;  1SH0 A;  2CPG A;  2K29 A;  3BSO A;  4LQ9 A;  3UPF A;  3IR7 A;  2JXH A;  1SIW A;  3SFU A;  3VW4 A;  2UUW A;  2WVC A;  4QPX A;  1B01 A;  2K1O A;  1OG7 A;  4AAI A;  2WVE A;  4HV0 A;  1EA4 A;  1ARQ A;  2CKW A;  2KEL A;  2KOE A;  2B43 A;  2RBF A;  2UUT A;  2KKE A;  3GXQ A;  4O4R A;  1BDT A;  2JBV A;  1SH2 A;  1QTG A;  2WVF A;  2BJ7 A;  2BJ8 A;  3LJP A;  2BNZ A;  3NNE A;  3NAH A;  2K5J A;  1B28 A;  4MJW A;  2CAD A;  1MYL A;  2BJ1 A;  1ARR A;  2K9I A;  4LRV A;  2JXG A;  3BSN A;  2GPE A;  3SFG A;  2BNW A;  2ADL A;  3FMT A;  4D8J A;  2JXI A;  4LQ3 A;  1U9P A;  1Q16 A;  2AY0 A;  1Q5V A;  1MNT A;  3QID A;  2Q2K A;  2WVB A;  1IRQ A;  2CA9 A;  2HZV A;  3QOQ A;  2CAX A;  1NLA A;  1SH3 A;  3LGH A;  4ME7 E; 
#chains in the Genus database with same CATH homology
 3VEB A;  2K1O A;  1ARR A;  2WVE A;  3H87 C;  3OD2 A;  1PAR A;  2K9I A;  4HV0 A;  2CAJ A;  2HZA A;  2WVD A;  1EA4 A;  2JXG A;  2BSQ E;  2GPE A;  2H1O E;  1ARQ A;  2KEL A;  1X93 A;  3VEA A;  2RBF A;  1BAZ A;  2BNW A;  3FMT A;  4D8J A;  3GXQ A;  2K6L A;  1BDT A;  2CPG A;  2K29 A;  2JXI A;  2BJ3 A;  2BA3 A;  1BDV A;  1U9P A;  2AY0 A;  1Q5V A;  1MNT A;  2JXH A;  1QTG A;  2WVB A;  2BJ9 A;  2WVF A;  2BJ7 A;  1IRQ A;  1P94 A;  2BJ8 A;  2CA9 A;  2HZV A;  2BNZ A;  3QOQ A;  3VW4 A;  4FXE A;  2CAX A;  2WVC A;  2K5J A;  3FT7 A;  1B28 A;  1B01 A;  1MYK A;  1NLA A;  1MYL A;  2CAD A;  2BJ1 A;  3LGH A;  4ME7 E; 
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