4FXE | Genus

Total Genus 19

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	19
sequence length	68
structure length	68
Chain Sequence	GSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Toxin/toxin inhibitor
source organism	Escherichia coli
publication title	The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity. pubmed doi rcsb
molecule keywords	Antitoxin RelB
total genus	19
structure length	68
sequence length	68
chains with identical sequence	B, C
ec nomenclature
pdb deposition date	2012-07-03

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF04221	RelB	RelB antitoxin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.1220.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant	Met repressor-like	4fxeA00

2CPGA 4FXEA 1EA4A 2WVBA 2JXGA 1MNTA 3VEBA 3H87C 2BA3A 1ARRA 3VEAA 2H1OE 1ARQA 1U9PA 2K9IA 3FMTA 4ME7E 2BJ1A 1Q5VA 2WVEA 1MYLA 2WVFA 1IRQA 2K5JA 1B01A 1P94A 2BNWA 2K1OA 2JXHA 3FT7A 2BSQE 2JXIA 2CA9A 2K6LA 2WVCA 3LGHA 3OD2A 1QTGA 2BJ3A 2HZAA 2WVDA 1PARA 2BNZA 3VW4A 2CADA 4HV0A 2RBFA 4D8JA 2AY0A 1BDVA 1X93A 2BJ9A 2K29A 1NLAA 1B28A 1BDTA 1MYKA 1BAZA 2CAJA 2CAXA 2GPEA 2KELA 2HZVA 3GXQA 3QOQA 2BJ7A 2BJ8A
chains in the Genus database with same CATH superfamily

2UUTA 4O4RA 1MNTA 2H3AA 1Q5VA 1MYLA 4QPXA 2BNWA 2CA9A 1QTGA 2BJ3A 4MJWA 2Q2KA 2AY0A 3UR0A 4LRVA 1NLAA 1MYKA 3NAHA 2CKWA 2GPEA 3QOQA 2BJ8A 1SH0A 3NAIA 2WVBA 4NRTA 3H87C 3NO7A 2ADLA 1OHNA 2BJ1A 1SH2A 1SH3A 1IRQA 3SFUA 1B01A 1P94A 3NNEA 2K1OA 2JXHA 2BSQE 4LQ9A 2JXIA 2K6LA 1Q16A 3LGHA 1OG7A 3VW4A 2BNZA 2CADA 4D8JA 2BJ9A 4NRUA 1BDTA 4AAIA 2WK4A 3LJPA 3G5OA 4FXEA 3VEBA 2BA3A 3VEAA 2H1OE 1ARQA 1U9PA 2K9IA 3FMTA 2WVFA 2AN7A 2HZAA 1PARA 1BDVA 3H5YA 2KKEA 1X93A 2JBVA 1B28A 3UQSA 2B43A 1BAZA 2CAJA 2HZVA 2BJ7A 2CPGA 3UPFA 3BSNA 1EA4A 2UUWA 2A2BA 2JXGA 3SFGA 1ARRA 4ME7E 2WVEA 2K5JA 3FT7A 2WVCA 3OD2A 2WVDA 4HV0A 2RBFA 2K29A 2KOEA 4LQ3A 3QIDA 2CAXA 2KELA 3IR7A 3BSOA 3H5XA 3GXQA 1SIWA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2CPG A;  4FXE A;  1EA4 A;  2WVB A;  2JXG A;  1MNT A;  3VEB A;  3H87 C;  2BA3 A;  1ARR A;  3VEA A;  2H1O E;  1ARQ A;  1U9P A;  2K9I A;  3FMT A;  4ME7 E;  2BJ1 A;  1Q5V A;  2WVE A;  1MYL A;  2WVF A;  1IRQ A;  2K5J A;  1B01 A;  1P94 A;  2BNW A;  2K1O A;  2JXH A;  3FT7 A;  2BSQ E;  2JXI A;  2CA9 A;  2K6L A;  2WVC A;  3LGH A;  3OD2 A;  1QTG A;  2BJ3 A;  2HZA A;  2WVD A;  1PAR A;  2BNZ A;  3VW4 A;  2CAD A;  4HV0 A;  2RBF A;  4D8J A;  2AY0 A;  1BDV A;  1X93 A;  2BJ9 A;  2K29 A;  1NLA A;  1B28 A;  1BDT A;  1MYK A;  1BAZ A;  2CAJ A;  2CAX A;  2GPE A;  2KEL A;  2HZV A;  3GXQ A;  3QOQ A;  2BJ7 A;  2BJ8 A; 
#chains in the Genus database with same CATH topology
 2UUT A;  4O4R A;  1MNT A;  2H3A A;  1Q5V A;  1MYL A;  4QPX A;  2BNW A;  2CA9 A;  1QTG A;  2BJ3 A;  4MJW A;  2Q2K A;  2AY0 A;  3UR0 A;  4LRV A;  1NLA A;  1MYK A;  3NAH A;  2CKW A;  2GPE A;  3QOQ A;  2BJ8 A;  1SH0 A;  3NAI A;  2WVB A;  4NRT A;  3H87 C;  3NO7 A;  2ADL A;  1OHN A;  2BJ1 A;  1SH2 A;  1SH3 A;  1IRQ A;  3SFU A;  1B01 A;  1P94 A;  3NNE A;  2K1O A;  2JXH A;  2BSQ E;  4LQ9 A;  2JXI A;  2K6L A;  1Q16 A;  3LGH A;  1OG7 A;  3VW4 A;  2BNZ A;  2CAD A;  4D8J A;  2BJ9 A;  4NRU A;  1BDT A;  4AAI A;  2WK4 A;  3LJP A;  3G5O A;  4FXE A;  3VEB A;  2BA3 A;  3VEA A;  2H1O E;  1ARQ A;  1U9P A;  2K9I A;  3FMT A;  2WVF A;  2AN7 A;  2HZA A;  1PAR A;  1BDV A;  3H5Y A;  2KKE A;  1X93 A;  2JBV A;  1B28 A;  3UQS A;  2B43 A;  1BAZ A;  2CAJ A;  2HZV A;  2BJ7 A;  2CPG A;  3UPF A;  3BSN A;  1EA4 A;  2UUW A;  2A2B A;  2JXG A;  3SFG A;  1ARR A;  4ME7 E;  2WVE A;  2K5J A;  3FT7 A;  2WVC A;  3OD2 A;  2WVD A;  4HV0 A;  2RBF A;  2K29 A;  2KOE A;  4LQ3 A;  3QID A;  2CAX A;  2KEL A;  3IR7 A;  3BSO A;  3H5X A;  3GXQ A;  1SIW A; 
#chains in the Genus database with same CATH homology
 2CPG A;  4FXE A;  1EA4 A;  2WVB A;  2JXG A;  1MNT A;  3VEB A;  3H87 C;  2BA3 A;  1ARR A;  3VEA A;  2H1O E;  1ARQ A;  1U9P A;  2K9I A;  3FMT A;  4ME7 E;  2BJ1 A;  1Q5V A;  2WVE A;  1MYL A;  2WVF A;  1IRQ A;  2K5J A;  1B01 A;  1P94 A;  2BNW A;  2K1O A;  2JXH A;  3FT7 A;  2BSQ E;  2JXI A;  2CA9 A;  2K6L A;  2WVC A;  3LGH A;  3OD2 A;  1QTG A;  2BJ3 A;  2HZA A;  2WVD A;  1PAR A;  2BNZ A;  3VW4 A;  2CAD A;  4HV0 A;  2RBF A;  4D8J A;  2AY0 A;  1BDV A;  1X93 A;  2BJ9 A;  2K29 A;  1NLA A;  1B28 A;  1BDT A;  1MYK A;  1BAZ A;  2CAJ A;  2CAX A;  2GPE A;  2KEL A;  2HZV A;  3GXQ A;  3QOQ A;  2BJ7 A;  2BJ8 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4FXEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations