1W61A

Proline racemase in complex with 2 molecules of pyrrole-2-carboxylic acid (holo form)
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
353
structure length
353
Chain Sequence
FKKSFTCIDMHTEGEAARIVTSGLPHIPGSNMAEKKAYLQENMDYLRRGIMLEPRGHDDMFGAFLFDPIEEGADLGIVFMDTGGYLNMCGHNSIAAVTAAVETGIVSVPAKATNVPVVLDTPAGLVRGTAHLQSGTESEVSNASIINVPSFLYQQDVVVVLPKPYGEVRVDIAFGGNFFAIVPAEQLGIDISVQNLSRLQEAGELLRTEINRSVKVQHPQLPHINTVDCVEIYGPPTNPEANYKNVVIFGNRQADRSPCGTGTSAKMATLYAKGQLRIGETFVYESILGSLFQGRVLGEERIPGVKVPVTKDAEEGMLVVTAEITGKAFIMGFNTMLFDPTDPFKNGFTLKQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure,Catalytic Mechanism and Mitogenic Properties of Trypanosoma Cruzi Proline Racemase
pubmed doi rcsb
molecule tags Racemase
source organism Trypanosoma cruzi
molecule keywords B-CELL MITOGEN
total genus 95
structure length 353
sequence length 353
chains with identical sequence B
ec nomenclature ec 5.1.1.4: Proline racemase.
pdb deposition date 2004-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05544 Pro_racemase Proline racemase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.10 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 1w61A02
3.10.310.10 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 1w61A01
5HA4A 5M47A 5H2YA 1XUAA 4JD7A 1SDJA 2Q9JA 4JBDA 1QYAA 1W61A 2Q9HA 1GQZA 1U1XA 1TM0A 4JUUA 4K8LA 1XUBA 2H9FA 2GKEA 1U1WA 1YM5A 2OTNA 1S7JA 3EJXA 4J9WA 5IWEA 1QY9A 3EKMA 4K7GB 4JCIA 1U0KA 4Q2HA 3EDNA 4IK0A 1W62A 4DUNA 1BWZA 4Q60A 2PVZA 5H2GA 1U1VA 4K7XA 2GKJA 3FVEA 2AZPA 4J9XA 1T6KA 3G7KA 2PW0A 4LB0A 4IJZA
chains in the Genus database with same CATH superfamily
1XUAA 2ZXPA 2QB7A 2MPBA 1IR6A 3WQZA 2ENXA 2GKEA 4OA3A 2OTNA 3EJXA 1QY9A 2ZXOA 1BWZA 2PVZA 3DEVA 4LG3A 2QB8A 3ICJA 2IW4A 1SDJA 2LT2A 1K23A 1QYAA 2Q9HA 1GQZA 4JUUA 4PY9A 2QB6A 1U0KA 4Q2HA 3EDNA 3IGHX 2HAWA 4K7XA 1T6KA 4LB0A 4IJZA 5HA4A 5H2YA 2ZVFA 2Q9JA 4LS9A 2EB0A 1TM0A 2KPTA 2ZXRA 2KW7A 1U1WA 1WPMA 1YM5A 1S7JA 3PTJA 4JCIA 1W62A 2YMAA 4Q60A 5H2GA 1U1VA 3FVEA 3PW9A 2AZPA 4J9XA 3G7KA 5ANPA 3W5WA 4GL6A 1K20A 5M47A 4JD7A 4JBDA 4RPAA 1W61A 4K8LA 1U1XA 1I74A 1XUBA 2H9FA 1WPPA 4J9WA 5IWEA 3EKMA 4K7GB 4IK0A 3PVHA 4DUNA 2GKJA 3G98A 2PW0A
chains in the Genus database with same CATH topology
1XUAA 2ZXPA 2QB7A 2MPBA 1IR6A 3WQZA 2ENXA 2GKEA 4OA3A 2OTNA 3EJXA 1QY9A 2ZXOA 1BWZA 2PVZA 3DEVA 4LG3A 2QB8A 3ICJA 2IW4A 1SDJA 2LT2A 1K23A 1QYAA 2Q9HA 1GQZA 4JUUA 4PY9A 2QB6A 1U0KA 4Q2HA 3EDNA 3IGHX 2HAWA 4K7XA 1T6KA 4LB0A 4IJZA 5HA4A 5H2YA 2ZVFA 2Q9JA 4LS9A 2EB0A 1TM0A 2KPTA 2ZXRA 2KW7A 1U1WA 1WPMA 1YM5A 1S7JA 3PTJA 4JCIA 1W62A 2YMAA 4Q60A 5H2GA 1U1VA 3FVEA 3PW9A 2AZPA 4J9XA 3G7KA 5ANPA 3W5WA 4GL6A 1K20A 5M47A 4JD7A 4JBDA 4RPAA 1W61A 4K8LA 1U1XA 1I74A 1XUBA 2H9FA 1WPPA 4J9WA 5IWEA 3EKMA 4K7GB 4IK0A 3PVHA 4DUNA 2GKJA 3G98A 2PW0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HA4 A;  5M47 A;  5H2Y A;  1XUA A;  4JD7 A;  1SDJ A;  2Q9J A;  4JBD A;  1QYA A;  1W61 A;  2Q9H A;  1GQZ A;  1U1X A;  1TM0 A;  4JUU A;  4K8L A;  1XUB A;  2H9F A;  2GKE A;  1U1W A;  1YM5 A;  2OTN A;  1S7J A;  3EJX A;  4J9W A;  5IWE A;  1QY9 A;  3EKM A;  4K7G B;  4JCI A;  1U0K A;  4Q2H A;  3EDN A;  4IK0 A;  1W62 A;  4DUN A;  1BWZ A;  4Q60 A;  2PVZ A;  5H2G A;  1U1V A;  4K7X A;  2GKJ A;  3FVE A;  2AZP A;  4J9X A;  1T6K A;  3G7K A;  2PW0 A;  4LB0 A;  4IJZ A; 
#chains in the Genus database with same CATH topology
 1XUA A;  2ZXP A;  2QB7 A;  2MPB A;  1IR6 A;  3WQZ A;  2ENX A;  2GKE A;  4OA3 A;  2OTN A;  3EJX A;  1QY9 A;  2ZXO A;  1BWZ A;  2PVZ A;  3DEV A;  4LG3 A;  2QB8 A;  3ICJ A;  2IW4 A;  1SDJ A;  2LT2 A;  1K23 A;  1QYA A;  2Q9H A;  1GQZ A;  4JUU A;  4PY9 A;  2QB6 A;  1U0K A;  4Q2H A;  3EDN A;  3IGH X;  2HAW A;  4K7X A;  1T6K A;  4LB0 A;  4IJZ A;  5HA4 A;  5H2Y A;  2ZVF A;  2Q9J A;  4LS9 A;  2EB0 A;  1TM0 A;  2KPT A;  2ZXR A;  2KW7 A;  1U1W A;  1WPM A;  1YM5 A;  1S7J A;  3PTJ A;  4JCI A;  1W62 A;  2YMA A;  4Q60 A;  5H2G A;  1U1V A;  3FVE A;  3PW9 A;  2AZP A;  4J9X A;  3G7K A;  5ANP A;  3W5W A;  4GL6 A;  1K20 A;  5M47 A;  4JD7 A;  4JBD A;  4RPA A;  1W61 A;  4K8L A;  1U1X A;  1I74 A;  1XUB A;  2H9F A;  1WPP A;  4J9W A;  5IWE A;  3EKM A;  4K7G B;  4IK0 A;  3PVH A;  4DUN A;  2GKJ A;  3G98 A;  2PW0 A; 
#chains in the Genus database with same CATH homology
 1XUA A;  2ZXP A;  2QB7 A;  2MPB A;  1IR6 A;  3WQZ A;  2ENX A;  2GKE A;  4OA3 A;  2OTN A;  3EJX A;  1QY9 A;  2ZXO A;  1BWZ A;  2PVZ A;  3DEV A;  4LG3 A;  2QB8 A;  3ICJ A;  2IW4 A;  1SDJ A;  2LT2 A;  1K23 A;  1QYA A;  2Q9H A;  1GQZ A;  4JUU A;  4PY9 A;  2QB6 A;  1U0K A;  4Q2H A;  3EDN A;  3IGH X;  2HAW A;  4K7X A;  1T6K A;  4LB0 A;  4IJZ A;  5HA4 A;  5H2Y A;  2ZVF A;  2Q9J A;  4LS9 A;  2EB0 A;  1TM0 A;  2KPT A;  2ZXR A;  2KW7 A;  1U1W A;  1WPM A;  1YM5 A;  1S7J A;  3PTJ A;  4JCI A;  1W62 A;  2YMA A;  4Q60 A;  5H2G A;  1U1V A;  3FVE A;  3PW9 A;  2AZP A;  4J9X A;  3G7K A;  5ANP A;  3W5W A;  4GL6 A;  1K20 A;  5M47 A;  4JD7 A;  4JBD A;  4RPA A;  1W61 A;  4K8L A;  1U1X A;  1I74 A;  1XUB A;  2H9F A;  1WPP A;  4J9W A;  5IWE A;  3EKM A;  4K7G B;  4IK0 A;  3PVH A;  4DUN A;  2GKJ A;  3G98 A;  2PW0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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