2GKEA

Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor ll-azidap
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
274
structure length
274
Chain Sequence
MQFSKMHGLGNDFVVVDGVTQNVFFTPETIRRLANRHCGIGFDQLLIVEAPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVTLKGLTNKKDISVSTQKGNMVLTVKDDNQIRVNMGEPIWEPAKIPFTANKFEKNYILRTDIQTVLCGAVSMGNPHCVVQVDDIQTANVEQLGPLLESHERFPERVNAGFMQIINKEHIKLRVYERGAGETQACGSGACAAVAVGIMQGLLNNNVQVDLPGGSLMIEWNGVGHPLYMTGEATHIYDGFITL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
source organism Haemophilus influenzae
publication title Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target.
pubmed doi rcsb
molecule keywords Diaminopimelate epimerase
total genus 80
structure length 274
sequence length 274
ec nomenclature ec 5.1.1.7: Diaminopimelate epimerase.
pdb deposition date 2006-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01678 DAP_epimerase Diaminopimelate epimerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.10 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 2gkeA02
3.10.310.10 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 2gkeA01
1S7JA 1TM0A 2AZPA 4JUUA 2Q9JA 4DUNA 3EKMA 4IK0A 5H2GA 4JBDA 2Q9HA 2GKJA 3FVEA 1XUAA 2PW0A 5IWEA 4J9XA 4JCIA 4K7XA 1QY9A 1U0KA 2PVZA 1U1WA 1W61A 4Q2HA 1QYAA 2H9FA 4IJZA 1SDJA 1W62A 3EJXA 5HA4A 4K8LA 2GKEA 1BWZA 1YM5A 3G7KA 5M47A 1U1VA 1XUBA 4J9WA 4JD7A 1U1XA 5H2YA 1GQZA 2OTNA 3EDNA 4Q60A 4K7GB 1T6KA 4LB0A
chains in the Genus database with same CATH superfamily
2AZPA 2EB0A 5H2GA 1K20A 2KW7A 2ZXPA 1U1WA 4LG3A 4Q2HA 4IJZA 3EJXA 1BWZA 2ZXOA 3ICJA 2LT2A 1U1XA 4RPAA 4Q60A 2HAWA 4LB0A 1TM0A 4IK0A 3PW9A 2YMAA 1I74A 4GL6A 3PTJA 2PVZA 2KPTA 2MPBA 1QYAA 3G7KA 1K23A 5M47A 1U1VA 4J9WA 3WQZA 3G98A 1WPPA 5H2YA 1GQZA 3EDNA 1IR6A 1T6KA 1S7JA 4DUNA 3DEVA 4OA3A 2QB7A 4JBDA 2Q9HA 2QB6A 3FVEA 4J9XA 1QY9A 1WPMA 2H9FA 1W62A 3IGHX 3PVHA 2IW4A 1YM5A 4JD7A 1XUBA 3W5WA 4JUUA 2Q9JA 4LS9A 3EKMA 2ZVFA 2GKJA 1XUAA 2PW0A 5IWEA 2QB8A 4JCIA 4K7XA 1U0KA 1W61A 1SDJA 5ANPA 5HA4A 4PY9A 4K8LA 2GKEA 2OTNA 2ZXRA 4K7GB 2ENXA
chains in the Genus database with same CATH topology
2AZPA 2EB0A 5H2GA 1K20A 2KW7A 2ZXPA 1U1WA 4LG3A 4Q2HA 4IJZA 3EJXA 1BWZA 2ZXOA 3ICJA 2LT2A 1U1XA 4RPAA 4Q60A 2HAWA 4LB0A 1TM0A 4IK0A 3PW9A 2YMAA 1I74A 4GL6A 3PTJA 2PVZA 2KPTA 2MPBA 1QYAA 3G7KA 1K23A 5M47A 1U1VA 4J9WA 3WQZA 3G98A 1WPPA 5H2YA 1GQZA 3EDNA 1IR6A 1T6KA 1S7JA 4DUNA 3DEVA 4OA3A 2QB7A 4JBDA 2Q9HA 2QB6A 3FVEA 4J9XA 1QY9A 1WPMA 2H9FA 1W62A 3IGHX 3PVHA 2IW4A 1YM5A 4JD7A 1XUBA 3W5WA 4JUUA 2Q9JA 4LS9A 3EKMA 2ZVFA 2GKJA 1XUAA 2PW0A 5IWEA 2QB8A 4JCIA 4K7XA 1U0KA 1W61A 1SDJA 5ANPA 5HA4A 4PY9A 4K8LA 2GKEA 2OTNA 2ZXRA 4K7GB 2ENXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S7J A;  1TM0 A;  2AZP A;  4JUU A;  2Q9J A;  4DUN A;  3EKM A;  4IK0 A;  5H2G A;  4JBD A;  2Q9H A;  2GKJ A;  3FVE A;  1XUA A;  2PW0 A;  5IWE A;  4J9X A;  4JCI A;  4K7X A;  1QY9 A;  1U0K A;  2PVZ A;  1U1W A;  1W61 A;  4Q2H A;  1QYA A;  2H9F A;  4IJZ A;  1SDJ A;  1W62 A;  3EJX A;  5HA4 A;  4K8L A;  2GKE A;  1BWZ A;  1YM5 A;  3G7K A;  5M47 A;  1U1V A;  1XUB A;  4J9W A;  4JD7 A;  1U1X A;  5H2Y A;  1GQZ A;  2OTN A;  3EDN A;  4Q60 A;  4K7G B;  1T6K A;  4LB0 A; 
#chains in the Genus database with same CATH topology
 2AZP A;  2EB0 A;  5H2G A;  1K20 A;  2KW7 A;  2ZXP A;  1U1W A;  4LG3 A;  4Q2H A;  4IJZ A;  3EJX A;  1BWZ A;  2ZXO A;  3ICJ A;  2LT2 A;  1U1X A;  4RPA A;  4Q60 A;  2HAW A;  4LB0 A;  1TM0 A;  4IK0 A;  3PW9 A;  2YMA A;  1I74 A;  4GL6 A;  3PTJ A;  2PVZ A;  2KPT A;  2MPB A;  1QYA A;  3G7K A;  1K23 A;  5M47 A;  1U1V A;  4J9W A;  3WQZ A;  3G98 A;  1WPP A;  5H2Y A;  1GQZ A;  3EDN A;  1IR6 A;  1T6K A;  1S7J A;  4DUN A;  3DEV A;  4OA3 A;  2QB7 A;  4JBD A;  2Q9H A;  2QB6 A;  3FVE A;  4J9X A;  1QY9 A;  1WPM A;  2H9F A;  1W62 A;  3IGH X;  3PVH A;  2IW4 A;  1YM5 A;  4JD7 A;  1XUB A;  3W5W A;  4JUU A;  2Q9J A;  4LS9 A;  3EKM A;  2ZVF A;  2GKJ A;  1XUA A;  2PW0 A;  5IWE A;  2QB8 A;  4JCI A;  4K7X A;  1U0K A;  1W61 A;  1SDJ A;  5ANP A;  5HA4 A;  4PY9 A;  4K8L A;  2GKE A;  2OTN A;  2ZXR A;  4K7G B;  2ENX A; 
#chains in the Genus database with same CATH homology
 2AZP A;  2EB0 A;  5H2G A;  1K20 A;  2KW7 A;  2ZXP A;  1U1W A;  4LG3 A;  4Q2H A;  4IJZ A;  3EJX A;  1BWZ A;  2ZXO A;  3ICJ A;  2LT2 A;  1U1X A;  4RPA A;  4Q60 A;  2HAW A;  4LB0 A;  1TM0 A;  4IK0 A;  3PW9 A;  2YMA A;  1I74 A;  4GL6 A;  3PTJ A;  2PVZ A;  2KPT A;  2MPB A;  1QYA A;  3G7K A;  1K23 A;  5M47 A;  1U1V A;  4J9W A;  3WQZ A;  3G98 A;  1WPP A;  5H2Y A;  1GQZ A;  3EDN A;  1IR6 A;  1T6K A;  1S7J A;  4DUN A;  3DEV A;  4OA3 A;  2QB7 A;  4JBD A;  2Q9H A;  2QB6 A;  3FVE A;  4J9X A;  1QY9 A;  1WPM A;  2H9F A;  1W62 A;  3IGH X;  3PVH A;  2IW4 A;  1YM5 A;  4JD7 A;  1XUB A;  3W5W A;  4JUU A;  2Q9J A;  4LS9 A;  3EKM A;  2ZVF A;  2GKJ A;  1XUA A;  2PW0 A;  5IWE A;  2QB8 A;  4JCI A;  4K7X A;  1U0K A;  1W61 A;  1SDJ A;  5ANP A;  5HA4 A;  4PY9 A;  4K8L A;  2GKE A;  2OTN A;  2ZXR A;  4K7G B;  2ENX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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