2GKJA

Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor dl-azidap
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
274
structure length
274
Chain Sequence
MQFSKMHGLGNDFVVVDGVTQNVFFTPETIRRLANRHCGIGFDQLLIVEAPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVTLKGLTNKKDISVSTQKGNMVLTVKDDNQIRVNMGEPIWEPAKIPFTANKFEKNYILRTDIQTVLCGAVSMGNPHCVVQVDDIQTANVEQLGPLLESHERFPERVNAGFMQIINKEHIKLRVYERGAGETQACGSGACAAVAVGIMQGLLNNNVQVDLPGGSLMIEWNGVGHPLYMTGEATHIYDGFITL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
source organism Haemophilus influenzae
publication title Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target.
pubmed doi rcsb
molecule keywords Diaminopimelate epimerase
total genus 82
structure length 274
sequence length 274
ec nomenclature ec 5.1.1.7: Diaminopimelate epimerase.
pdb deposition date 2006-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01678 DAP_epimerase Diaminopimelate epimerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.10 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 2gkjA02
3.10.310.10 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 2gkjA01
1W61A 4JD7A 4DUNA 4K8LA 3FVEA 2GKEA 4Q60A 4K7GB 1T6KA 2PVZA 1GQZA 3G7KA 3EDNA 1SDJA 1YM5A 4J9WA 3EJXA 1W62A 2Q9JA 5H2GA 5HA4A 4JBDA 5IWEA 1U0KA 5H2YA 1U1WA 2PW0A 4IK0A 1XUBA 4JCIA 3EKMA 1QY9A 1U1XA 4IJZA 5M47A 4J9XA 2OTNA 1BWZA 2GKJA 1QYAA 1S7JA 4Q2HA 1TM0A 4JUUA 2AZPA 4LB0A 4K7XA 2Q9HA 1XUAA 2H9FA 1U1VA
chains in the Genus database with same CATH superfamily
1I74A 4JD7A 3WQZA 3W5WA 4LS9A 3EDNA 4J9WA 5ANPA 2YMAA 4JBDA 1K23A 4PY9A 2PW0A 2EB0A 1BWZA 1QYAA 4Q2HA 2AZPA 4K7XA 1U1VA 4DUNA 2QB7A 3IGHX 3FVEA 4Q60A 2PVZA 3G7KA 1W62A 2HAWA 2IW4A 2ZXRA 3PW9A 2KPTA 3PTJA 1QY9A 1U1XA 4IJZA 4JUUA 2Q9HA 1IR6A 3ICJA 2H9FA 1K20A 2QB6A 2GKEA 4K7GB 4OA3A 5H2GA 3G98A 1U0KA 5H2YA 4RPAA 4IK0A 3EKMA 5M47A 1XUAA 4J9XA 2OTNA 4GL6A 1S7JA 1TM0A 2QB8A 2ZXOA 4LB0A 1W61A 4K8LA 1WPMA 1T6KA 1GQZA 2ENXA 1SDJA 1YM5A 2KW7A 3EJXA 2Q9JA 3DEVA 4LG3A 5HA4A 1U1WA 1XUBA 4JCIA 2ZVFA 2GKJA 2MPBA 2LT2A 2ZXPA 3PVHA 5IWEA 1WPPA
chains in the Genus database with same CATH topology
1I74A 4JD7A 3WQZA 3W5WA 4LS9A 3EDNA 4J9WA 5ANPA 2YMAA 4JBDA 1K23A 4PY9A 2PW0A 2EB0A 1BWZA 1QYAA 4Q2HA 2AZPA 4K7XA 1U1VA 4DUNA 2QB7A 3IGHX 3FVEA 4Q60A 2PVZA 3G7KA 1W62A 2HAWA 2IW4A 2ZXRA 3PW9A 2KPTA 3PTJA 1QY9A 1U1XA 4IJZA 4JUUA 2Q9HA 1IR6A 3ICJA 2H9FA 1K20A 2QB6A 2GKEA 4K7GB 4OA3A 5H2GA 3G98A 1U0KA 5H2YA 4RPAA 4IK0A 3EKMA 5M47A 1XUAA 4J9XA 2OTNA 4GL6A 1S7JA 1TM0A 2QB8A 2ZXOA 4LB0A 1W61A 4K8LA 1WPMA 1T6KA 1GQZA 2ENXA 1SDJA 1YM5A 2KW7A 3EJXA 2Q9JA 3DEVA 4LG3A 5HA4A 1U1WA 1XUBA 4JCIA 2ZVFA 2GKJA 2MPBA 2LT2A 2ZXPA 3PVHA 5IWEA 1WPPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W61 A;  4JD7 A;  4DUN A;  4K8L A;  3FVE A;  2GKE A;  4Q60 A;  4K7G B;  1T6K A;  2PVZ A;  1GQZ A;  3G7K A;  3EDN A;  1SDJ A;  1YM5 A;  4J9W A;  3EJX A;  1W62 A;  2Q9J A;  5H2G A;  5HA4 A;  4JBD A;  5IWE A;  1U0K A;  5H2Y A;  1U1W A;  2PW0 A;  4IK0 A;  1XUB A;  4JCI A;  3EKM A;  1QY9 A;  1U1X A;  4IJZ A;  5M47 A;  4J9X A;  2OTN A;  1BWZ A;  2GKJ A;  1QYA A;  1S7J A;  4Q2H A;  1TM0 A;  4JUU A;  2AZP A;  4LB0 A;  4K7X A;  2Q9H A;  1XUA A;  2H9F A;  1U1V A; 
#chains in the Genus database with same CATH topology
 1I74 A;  4JD7 A;  3WQZ A;  3W5W A;  4LS9 A;  3EDN A;  4J9W A;  5ANP A;  2YMA A;  4JBD A;  1K23 A;  4PY9 A;  2PW0 A;  2EB0 A;  1BWZ A;  1QYA A;  4Q2H A;  2AZP A;  4K7X A;  1U1V A;  4DUN A;  2QB7 A;  3IGH X;  3FVE A;  4Q60 A;  2PVZ A;  3G7K A;  1W62 A;  2HAW A;  2IW4 A;  2ZXR A;  3PW9 A;  2KPT A;  3PTJ A;  1QY9 A;  1U1X A;  4IJZ A;  4JUU A;  2Q9H A;  1IR6 A;  3ICJ A;  2H9F A;  1K20 A;  2QB6 A;  2GKE A;  4K7G B;  4OA3 A;  5H2G A;  3G98 A;  1U0K A;  5H2Y A;  4RPA A;  4IK0 A;  3EKM A;  5M47 A;  1XUA A;  4J9X A;  2OTN A;  4GL6 A;  1S7J A;  1TM0 A;  2QB8 A;  2ZXO A;  4LB0 A;  1W61 A;  4K8L A;  1WPM A;  1T6K A;  1GQZ A;  2ENX A;  1SDJ A;  1YM5 A;  2KW7 A;  3EJX A;  2Q9J A;  3DEV A;  4LG3 A;  5HA4 A;  1U1W A;  1XUB A;  4JCI A;  2ZVF A;  2GKJ A;  2MPB A;  2LT2 A;  2ZXP A;  3PVH A;  5IWE A;  1WPP A; 
#chains in the Genus database with same CATH homology
 1I74 A;  4JD7 A;  3WQZ A;  3W5W A;  4LS9 A;  3EDN A;  4J9W A;  5ANP A;  2YMA A;  4JBD A;  1K23 A;  4PY9 A;  2PW0 A;  2EB0 A;  1BWZ A;  1QYA A;  4Q2H A;  2AZP A;  4K7X A;  1U1V A;  4DUN A;  2QB7 A;  3IGH X;  3FVE A;  4Q60 A;  2PVZ A;  3G7K A;  1W62 A;  2HAW A;  2IW4 A;  2ZXR A;  3PW9 A;  2KPT A;  3PTJ A;  1QY9 A;  1U1X A;  4IJZ A;  4JUU A;  2Q9H A;  1IR6 A;  3ICJ A;  2H9F A;  1K20 A;  2QB6 A;  2GKE A;  4K7G B;  4OA3 A;  5H2G A;  3G98 A;  1U0K A;  5H2Y A;  4RPA A;  4IK0 A;  3EKM A;  5M47 A;  1XUA A;  4J9X A;  2OTN A;  4GL6 A;  1S7J A;  1TM0 A;  2QB8 A;  2ZXO A;  4LB0 A;  1W61 A;  4K8L A;  1WPM A;  1T6K A;  1GQZ A;  2ENX A;  1SDJ A;  1YM5 A;  2KW7 A;  3EJX A;  2Q9J A;  3DEV A;  4LG3 A;  5HA4 A;  1U1W A;  1XUB A;  4JCI A;  2ZVF A;  2GKJ A;  2MPB A;  2LT2 A;  2ZXP A;  3PVH A;  5IWE A;  1WPP A; 
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similar chains in the pdb database (?% sequence similarity)

 
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