1PV6A

Crystal structure of lactose permease
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
417
structure length
417
Chain Sequence
MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALGASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Escherichia coli
publication title Structure and mechanism of the lactose permease of Escherichia coli
pubmed doi rcsb
molecule keywords Lactose permease
total genus 141
structure length 417
sequence length 417
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01306 LacY_symp LacY proton/sugar symporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 1pv6A02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 1pv6A01
4Q65A 5A2OA 4JR9A 5D58A 4TPGA 4PYPA 3O7PA 4IKZA 1PW4A 5D6KA 5EQGA 5C65A 1PV6A 4OH3A 3O7QA 5EQHA 4ZWBA 4IKWA 4YB9D 2CFQA 2XUTA 4IU9A 3WDOA 2CFPA 4JREA 5EQIA 4TPJA 4D2CA 4JA3A 4UVMA 4ZYRA 4W6VA 4XNJA 4D2BA 4U4WA 4OAAA 4ZW9A 4GBYA 4IU8A 4XNIA 4GBZA 2Y5YA 4YBQA 4TPHA 4LDSA 4ZWCA 2V8NA 4APSA 4IKVA 4LEPA 4D2DA 5GXBA 4IKYA 1PV7A 4GC0A 4QIQA 5A2NA 4J05A 4U4VA 5D59A 4U4TA 4IKXA
chains in the Genus database with same CATH superfamily
1Y1WD 1SCFA 2INTA 4IU9A 4A3GD 3D48P 2O27A 3BPOA 4IU8A 3QB7A 1P9MB 1D9CA 3HOXD 3PIVA 1ILKA 5IP9D 1PV7A 4QIQA 4YDYI 4J4LC 2PSMA 1JLIA 2KZ1A 5L6YC 3L5WI 4NN5A 1IARA 2CFPA 4JREA 5LQBA 4ZYRA 1IJZA 4D2BA 1I1RB 2H24A 4BY7D 2GMFA 3SE4B 1LK3A 1Y6NL 1KF9A 3HHCA 3NCCA 5C44D 4D2DA 1M47A 2B8XA 3QAZA 4U4TA 2XQBA 4PS4A 4BBSD 4X51A 4GRWA 4ZF7A 1M4CA 1M48A 4A3KD 2Q98A 4ZWBA 3QWRB 3QT2C 1ETEA 2Z3RA 3WDOA 5EQIA 4NI7A 1A7MA 3UF5A 1BGCA 2V8NA 3DGCL 3BPLA 2B5IA 5D58A 1RHGA 5E4EA 5D28B 1Y14A 2OQPA 2JA5D 1EERA 5IYBD 2C35A 3DLQI 2ERJD 2Z3QA 1CSGA 5KNHI 3HOWD 5FLMD 4GS7A 4YUEC 4JR9A 1FYHA 5EQGA 3NPZA 3HOZD 3H3VE 1EKUA 5C4XD 4XNIA 1NBPA 1M4AA 4APSA 4J05A 1EMRA 5C3ED 1HWHA 4IKZA 4ZS7A 3FKID 3VA2A 2R92D 4D2CA 4W6VA 4U4WA 4EXPA 1B5LA 1Y6KL 3N06A 4ZWCA 1IL6A 2B63D 5D71A 4MHLA 3IRHA 1IK0A 1AU1A 3H0GD 1YKBA 3O7QA 4WRLB 1ITFA 4NN7A 1GA3A 2Q7NB 4JA3A 1RCBA 5FUCA 1QVNA 2L3YA 2CYKA 3PIWA 4A3BD 3BPNA 5C7XA 1Y1VD 4BBRD 5IYDD 5D59A 1AX8A 4IKXA 4NN6A 1VLKA 5TS9A 3O7PA 5D6KA 5C65A 1M4RA 3PO3D 3I4MD 2XUTA 1IRLA 3EJJA 3PO2D 3INKC 4GBYA 4A3JD 2HYMB 4GBZA 4NEMA 3L5XA 4LDSA 1V7NV 2L3OA 1EXZA 3B5KA 3OG6A 1CYLA 2B8ZA 1M4BA 4BXXD 1HWGA 1LQSL 1PW6A 5IYCD 3D87A 1BUYA 3NCEA 3OG4A 2ILKA 1RW5A 2B8UA 3BESL 2Q14A 1HUWA 3NCBA 4TPHA 1RFBA 1V7MV 4EXNA 3G9VB 2R93D 4IKYA 1BCNA 5A2OA 4BY1D 5D22A 1PW4A 1PV6A 3N0PA 4A3LD 1A22A 1PGRA 2VUMD 4XNJA 1D9GA 3HOYD 1WU3I 2JA6D 4IKVA 5A2NA 1M49A 4Z5RD 1J7VL 2B8YA 3LB6B 2R7ZD 1Y6ML 1PVHB 4LRLA 3HOUD 4DOHA 2Y5YA 2B91A 4DKEA 4NKQC 4LEPA 4A3MD 5IP7D 3HOVD 4PYPA 4A3ED 1CD9A 1CN4C 3QB1A 4NI9A 3TGXB 4TPJA 2D9QA 1WCMD 4O6KA 2D48A 4A93D 2LMSA 4CNIC 4O9HA 4A3FD 4GC0A 1HGUA 4U4VA 2LAGA 1F6FA 1INRA 2B90A 4OH3A 3HHRA 2E9WC 1CNT1 3HMXB 3Q1SI 3S9DA 1ITMA 2CFQA 1PY2A 4YQXA 4DKDA 3UF2A 4A3DD 4FA8E 4Q65A 1BGDA 3MZGA 5EQHA 3OQ3A 3WCYI 4DKFA 4YB9D 2O6IA 3NCFA 1AXIA 4OAAA 4YPGC 1Z7CA 1LKIA 3LB6A 3AYHA 1BBNA 4RS1A 5D70A 3DI2A 3G6DA 1N1FA 4I77Z 4TPGA 1HIKA 2JA8D 4IKWA 3DI3A 1GNCA 1HIJA 3DUHC 4DKCA 3I4ND 1EVSA 1ALUA 1BP3A 1BGEA 1HZIA 3UX9A 2JA7D 1Z92A 1FG9A 5GXBA 5D72A 5FHXA 3EW3A 1HULA 4NEJA 4UVMA 2IL6A 3SE3B 3UEZE 4ZW9A 4A3ID 1F45B 2O26A 4YBQA 3D85C 1ITIA 4A3CD 1ITLA
chains in the Genus database with same CATH topology
4Q65A 5A2OA 4JR9A 5D58A 4TPGA 4PYPA 3O7PA 4IKZA 1PW4A 5D6KA 5EQGA 5C65A 1PV6A 4OH3A 3O7QA 5EQHA 4ZWBA 4IKWA 4YB9D 2CFQA 2XUTA 4IU9A 3WDOA 2CFPA 4JREA 5EQIA 4TPJA 4D2CA 4JA3A 4UVMA 4ZYRA 4W6VA 4XNJA 4D2BA 4U4WA 4OAAA 4ZW9A 4GBYA 4IU8A 4XNIA 4GBZA 2Y5YA 4YBQA 4TPHA 4LDSA 4ZWCA 2V8NA 4APSA 4IKVA 4LEPA 4D2DA 5GXBA 4IKYA 1PV7A 4GC0A 4QIQA 5A2NA 4J05A 4U4VA 5D59A 4U4TA 4IKXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q65 A;  5A2O A;  4JR9 A;  5D58 A;  4TPG A;  4PYP A;  3O7P A;  4IKZ A;  1PW4 A;  5D6K A;  5EQG A;  5C65 A;  1PV6 A;  4OH3 A;  3O7Q A;  5EQH A;  4ZWB A;  4IKW A;  4YB9 D;  2CFQ A;  2XUT A;  4IU9 A;  3WDO A;  2CFP A;  4JRE A;  5EQI A;  4TPJ A;  4D2C A;  4JA3 A;  4UVM A;  4ZYR A;  4W6V A;  4XNJ A;  4D2B A;  4U4W A;  4OAA A;  4ZW9 A;  4GBY A;  4IU8 A;  4XNI A;  4GBZ A;  2Y5Y A;  4YBQ A;  4TPH A;  4LDS A;  4ZWC A;  2V8N A;  4APS A;  4IKV A;  4LEP A;  4D2D A;  5GXB A;  4IKY A;  1PV7 A;  4GC0 A;  4QIQ A;  5A2N A;  4J05 A;  4U4V A;  5D59 A;  4U4T A;  4IKX A; 
#chains in the Genus database with same CATH topology
 1Y1W D;  1SCF A;  2INT A;  4IU9 A;  4A3G D;  3D48 P;  2O27 A;  3BPO A;  4IU8 A;  3QB7 A;  1P9M B;  1D9C A;  3HOX D;  3PIV A;  1ILK A;  5IP9 D;  1PV7 A;  4QIQ A;  4YDY I;  4J4L C;  2PSM A;  1JLI A;  2KZ1 A;  5L6Y C;  3L5W I;  4NN5 A;  1IAR A;  2CFP A;  4JRE A;  5LQB A;  4ZYR A;  1IJZ A;  4D2B A;  1I1R B;  2H24 A;  4BY7 D;  2GMF A;  3SE4 B;  1LK3 A;  1Y6N L;  1KF9 A;  3HHC A;  3NCC A;  5C44 D;  4D2D A;  1M47 A;  2B8X A;  3QAZ A;  4U4T A;  2XQB A;  4PS4 A;  4BBS D;  4X51 A;  4GRW A;  4ZF7 A;  1M4C A;  1M48 A;  4A3K D;  2Q98 A;  4ZWB A;  3QWR B;  3QT2 C;  1ETE A;  2Z3R A;  3WDO A;  5EQI A;  4NI7 A;  1A7M A;  3UF5 A;  1BGC A;  2V8N A;  3DGC L;  3BPL A;  2B5I A;  5D58 A;  1RHG A;  5E4E A;  5D28 B;  1Y14 A;  2OQP A;  2JA5 D;  1EER A;  5IYB D;  2C35 A;  3DLQ I;  2ERJ D;  2Z3Q A;  1CSG A;  5KNH I;  3HOW D;  5FLM D;  4GS7 A;  4YUE C;  4JR9 A;  1FYH A;  5EQG A;  3NPZ A;  3HOZ D;  3H3V E;  1EKU A;  5C4X D;  4XNI A;  1NBP A;  1M4A A;  4APS A;  4J05 A;  1EMR A;  5C3E D;  1HWH A;  4IKZ A;  4ZS7 A;  3FKI D;  3VA2 A;  2R92 D;  4D2C A;  4W6V A;  4U4W A;  4EXP A;  1B5L A;  1Y6K L;  3N06 A;  4ZWC A;  1IL6 A;  2B63 D;  5D71 A;  4MHL A;  3IRH A;  1IK0 A;  1AU1 A;  3H0G D;  1YKB A;  3O7Q A;  4WRL B;  1ITF A;  4NN7 A;  1GA3 A;  2Q7N B;  4JA3 A;  1RCB A;  5FUC A;  1QVN A;  2L3Y A;  2CYK A;  3PIW A;  4A3B D;  3BPN A;  5C7X A;  1Y1V D;  4BBR D;  5IYD D;  5D59 A;  1AX8 A;  4IKX A;  4NN6 A;  1VLK A;  5TS9 A;  3O7P A;  5D6K A;  5C65 A;  1M4R A;  3PO3 D;  3I4M D;  2XUT A;  1IRL A;  3EJJ A;  3PO2 D;  3INK C;  4GBY A;  4A3J D;  2HYM B;  4GBZ A;  4NEM A;  3L5X A;  4LDS A;  1V7N V;  2L3O A;  1EXZ A;  3B5K A;  3OG6 A;  1CYL A;  2B8Z A;  1M4B A;  4BXX D;  1HWG A;  1LQS L;  1PW6 A;  5IYC D;  3D87 A;  1BUY A;  3NCE A;  3OG4 A;  2ILK A;  1RW5 A;  2B8U A;  3BES L;  2Q14 A;  1HUW A;  3NCB A;  4TPH A;  1RFB A;  1V7M V;  4EXN A;  3G9V B;  2R93 D;  4IKY A;  1BCN A;  5A2O A;  4BY1 D;  5D22 A;  1PW4 A;  1PV6 A;  3N0P A;  4A3L D;  1A22 A;  1PGR A;  2VUM D;  4XNJ A;  1D9G A;  3HOY D;  1WU3 I;  2JA6 D;  4IKV A;  5A2N A;  1M49 A;  4Z5R D;  1J7V L;  2B8Y A;  3LB6 B;  2R7Z D;  1Y6M L;  1PVH B;  4LRL A;  3HOU D;  4DOH A;  2Y5Y A;  2B91 A;  4DKE A;  4NKQ C;  4LEP A;  4A3M D;  5IP7 D;  3HOV D;  4PYP A;  4A3E D;  1CD9 A;  1CN4 C;  3QB1 A;  4NI9 A;  3TGX B;  4TPJ A;  2D9Q A;  1WCM D;  4O6K A;  2D48 A;  4A93 D;  2LMS A;  4CNI C;  4O9H A;  4A3F D;  4GC0 A;  1HGU A;  4U4V A;  2LAG A;  1F6F A;  1INR A;  2B90 A;  4OH3 A;  3HHR A;  2E9W C;  1CNT 1;  3HMX B;  3Q1S I;  3S9D A;  1ITM A;  2CFQ A;  1PY2 A;  4YQX A;  4DKD A;  3UF2 A;  4A3D D;  4FA8 E;  4Q65 A;  1BGD A;  3MZG A;  5EQH A;  3OQ3 A;  3WCY I;  4DKF A;  4YB9 D;  2O6I A;  3NCF A;  1AXI A;  4OAA A;  4YPG C;  1Z7C A;  1LKI A;  3LB6 A;  3AYH A;  1BBN A;  4RS1 A;  5D70 A;  3DI2 A;  3G6D A;  1N1F A;  4I77 Z;  4TPG A;  1HIK A;  2JA8 D;  4IKW A;  3DI3 A;  1GNC A;  1HIJ A;  3DUH C;  4DKC A;  3I4N D;  1EVS A;  1ALU A;  1BP3 A;  1BGE A;  1HZI A;  3UX9 A;  2JA7 D;  1Z92 A;  1FG9 A;  5GXB A;  5D72 A;  5FHX A;  3EW3 A;  1HUL A;  4NEJ A;  4UVM A;  2IL6 A;  3SE3 B;  3UEZ E;  4ZW9 A;  4A3I D;  1F45 B;  2O26 A;  4YBQ A;  3D85 C;  1ITI A;  4A3C D;  1ITL A; 
#chains in the Genus database with same CATH homology
 4Q65 A;  5A2O A;  4JR9 A;  5D58 A;  4TPG A;  4PYP A;  3O7P A;  4IKZ A;  1PW4 A;  5D6K A;  5EQG A;  5C65 A;  1PV6 A;  4OH3 A;  3O7Q A;  5EQH A;  4ZWB A;  4IKW A;  4YB9 D;  2CFQ A;  2XUT A;  4IU9 A;  3WDO A;  2CFP A;  4JRE A;  5EQI A;  4TPJ A;  4D2C A;  4JA3 A;  4UVM A;  4ZYR A;  4W6V A;  4XNJ A;  4D2B A;  4U4W A;  4OAA A;  4ZW9 A;  4GBY A;  4IU8 A;  4XNI A;  4GBZ A;  2Y5Y A;  4YBQ A;  4TPH A;  4LDS A;  4ZWC A;  2V8N A;  4APS A;  4IKV A;  4LEP A;  4D2D A;  5GXB A;  4IKY A;  1PV7 A;  4GC0 A;  4QIQ A;  5A2N A;  4J05 A;  4U4V A;  5D59 A;  4U4T A;  4IKX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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