4A93D

Rna polymerase ii elongation complex containing a cpd lesion
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
pubmed doi rcsb
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
molecule tags Transcription
total genus 49
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a93D02
4A3MD 3HOZD 5C3ED 3H3VE 2B63D 4A93D 3I4MD 5IP7D 3FKID 2JA5D 3HOYD 5C44D 3HOUD 4A3JD 1Y1WD 4A3DD 5FLMD 5IYBD 4BBSD 3PO2D 1WCMD 4A3FD 4A3CD 3I4ND 2R7ZD 4A3BD 3AYHA 2R93D 5IP9D 4BY7D 1Y1VD 4A3GD 3H0GD 2JA7D 2C35A 4BBRD 5IYCD 3PO3D 3HOWD 3HOXD 2VUMD 2R92D 2JA8D 4A3ID 4A3KD 4A3ED 2JA6D 4BY1D 3HOVD 1Y14A 5IYDD 5C4XD 4A3LD 4BXXD
chains in the Genus database with same CATH superfamily
1CD9A 1PY2A 3FKID 5EQGA 3UF5A 1EXZA 4ZW9A 2B8XA 1ITFA 1HULA 5IP9D 1RFBA 2CFPA 2L3YA 3EJJA 4YB9D 4NEJA 2ILKA 2PSMA 3DUHC 1FG9A 3G6DA 1IK0A 4JR9A 4DKCA 4NEMA 5GXBA 5C3ED 3LB6A 1HGUA 4NN6A 4Q65A 5D71A 3D85C 3D87A 5A2NA 3NPZA 1BGEA 3O7PA 1V7MV 4YPGC 4ZYRA 1IARA 4PS4A 1AU1A 5EQIA 3PIVA 2ERJD 3VA2A 1ALUA 1PV7A 2B5IA 4QIQA 4Z5RD 4IKYA 3HHCA 4IKWA 4D2DA 3BESL 3I4ND 3AYHA 3OG4A 1HWHA 4BY7D 2CFQA 4WRLB 2XUTA 1CNT1 3OG6A 4I77Z 2JA6D 1F45B 3BPNA 4BXXD 3QB1A 4XNJA 1HZIA 1ITIA 2JA5D 3BPOA 3INKC 5C7XA 1WCMD 1BBNA 1ITMA 1Y6NL 4A3BD 5C65A 4IU9A 2IL6A 3LB6B 2O26A 4NN5A 5A2OA 1RCBA 1BCNA 3HMXB 4A3LD 2O6IA 1HIJA 1PW4A 4GBZA 1CSGA 4DKDA 2LMSA 4GC0A 4EXPA 3HOUD 4A3DD 4DKFA 2L3OA 2B90A 2INTA 1Y6ML 4BBRD 1IJZA 4NN7A 1PW6A 3PO3D 2R92D 2JA8D 1ITLA 3HOVD 4BY1D 1A7MA 1WU3I 4U4TA 4JREA 1EVSA 5EQHA 4GRWA 1ILKA 4BBSD 1HIKA 2CYKA 1B5LA 1LKIA 1D9GA 1SCFA 2C35A 4X51A 3DI2A 4A3ED 4ZWCA 1IRLA 4PYPA 4XNIA 1NBPA 1PVHB 4J05A 3WDOA 3UX9A 3Q1SI 4D2BA 4A3FD 4YBQA 4NKQC 5D28B 2Q7NB 2H24A 3DLQI 3HHRA 3NCBA 3QT2C 1PGRA 5IYCD 3DGCL 1AXIA 4YQXA 2Z3RA 5D6KA 2Z3QA 4W6VA 2KZ1A 1YKBA 3DI3A 3H3VE 5C44D 5FLMD 1M48A 2B8YA 1M4CA 4IKVA 5KNHI 1Z7CA 1Y1VD 5D22A 4UVMA 1GNCA 4LEPA 2E9WC 1RW5A 3NCFA 1P9MB 4DOHA 4GBYA 2OQPA 4NI9A 5D72A 1Y6KL 2JA7D 1AX8A 1EKUA 3NCCA 3G9VB 4YDYI 3UF2A 3SE3B 4TPHA 2V8NA 3H0GD 4CNIC 2B91A 2B63D 3UEZE 1Y1WD 1EMRA 4FA8E 1V7NV 1ETEA 4TPJA 4ZWBA 1FYHA 3BPLA 2Y5YA 4ZS7A 1I1RB 4A3KD 4RS1A 1LK3A 4A93D 2D48A 4YUEC 3QB7A 4IKZA 2R93D 5D70A 4OH3A 1VLKA 4O6KA 3HOXD 3D48P 4A3ID 1QVNA 1J7VL 1M47A 5C4XD 2LAGA 3HOZD 4TPGA 4U4VA 1Z92A 3EW3A 2HYMB 5L6YC 5LQBA 3N06A 2D9QA 4U4WA 2O27A 1M4AA 2VUMD 3OQ3A 4IKXA 1CN4C 2B8UA 5IYDD 1D9CA 2B8ZA 5D59A 1BGDA 1M4BA 4A3JD 5E4EA 4ZF7A 1HUWA 4D2CA 3PIWA 5FHXA 4NI7A 4A3CD 3IRHA 1CYLA 3NCEA 4EXNA 2Q98A 3O7QA 3HOWD 3L5XA 4LDSA 1PV6A 3QAZA 5TS9A 1Y14A 1GA3A 1IL6A 3N0PA 5IP7D 3HOYD 1JLIA 1KF9A 1A22A 4GS7A 2GMFA 1BGCA 2R7ZD 3MZGA 4OAAA 3L5WI 4A3GD 4MHLA 1HWGA 3S9DA 4LRLA 4IU8A 1LQSL 1BUYA 4J4LC 1RHGA 5D58A 1N1FA 3QWRB 5FUCA 1F6FA 5IYBD 3TGXB 4DKEA 1M49A 3WCYI 2XQBA 4A3MD 1INRA 2Q14A 1EERA 3I4MD 1BP3A 4O9HA 3PO2D 3B5KA 4APSA 1M4RA 4JA3A 3SE4B
chains in the Genus database with same CATH topology
2O6IA 1RW5A 1HIJA 2B8ZA 1CD9A 1CSGA 1P9MB 1BGDA 3NCFA 1PY2A 3FKID 1M4BA 2LMSA 4DKDA 4EXPA 3HOUD 3UF5A 1EXZA 4A3JD 5E4EA 4A3DD 4DOHA 4ZF7A 1HUWA 3PIWA 5FHXA 4NI7A 2B8XA 4A3CD 3IRHA 1ITFA 1HULA 4DKFA 2OQPA 4NI9A 5IP9D 5D72A 1RFBA 2L3OA 1CYLA 2B90A 2INTA 3NCEA 1Y6KL 2L3YA 3EJJA 1AX8A 1Y6ML 4EXNA 2JA7D 2Q98A 2ILKA 4NEJA 1IJZA 1EKUA 2PSMA 1PW6A 3DUHC 3NCCA 4NN7A 4BBRD 3HOWD 3PO3D 3G9VB 2R92D 1FG9A 3G6DA 3L5XA 4YDYI 2JA8D 1IK0A 3UF2A 1ITLA 3QAZA 3SE3B 5TS9A 4DKCA 3HOVD 4NEMA 1Y14A 4BY1D 3H0GD 1GA3A 1A7MA 1IL6A 1WU3I 4CNIC 5C3ED 2B91A 3LB6A 3N0PA 1EVSA 2B63D 5IP7D 3HOYD 1JLIA 4GRWA 1ILKA 1HGUA 1KF9A 1A22A 3UEZE 4GS7A 1Y1WD 1EMRA 4NN6A 2GMFA 4FA8E 5D71A 1V7NV 1HIKA 3D85C 3D87A 4BBSD 3NPZA 1BGEA 2CYKA 1B5LA 1LKIA 1BGCA 2R7ZD 1D9GA 3MZGA 1ETEA 1SCFA 3L5WI 1FYHA 3BPLA 4A3GD 4MHLA 2C35A 1HWGA 4ZS7A 1V7MV 4YPGC 1IARA 3S9DA 4X51A 4PS4A 3DI2A 1I1RB 4LRLA 4A3KD 1AU1A 1LQSL 4A3ED 1IRLA 3PIVA 2ERJD 1BUYA 4J4LC 3VA2A 1ALUA 4RS1A 1RHGA 2B5IA 4Z5RD 1NBPA 1LK3A 4A93D 1N1FA 2D48A 3QWRB 5FUCA 1PVHB 4YUEC 1F6FA 3HHCA 3TGXB 3UX9A 3Q1SI 3QB7A 5IYBD 4A3FD 3BESL 4NKQC 3I4ND 3AYHA 5D28B 3OG4A 2Q7NB 2R93D 4DKEA 1HWHA 2H24A 3DLQI 5D70A 4BY7D 4WRLB 3HHRA 3NCBA 1VLKA 3OG6A 1CNT1 1PGRA 3QT2C 5IYCD 3DGCL 1AXIA 4YQXA 4O6KA 3HOXD 2Z3RA 1M49A 3D48P 4A3ID 3WCYI 4I77Z 2XQBA 1QVNA 1J7VL 2JA6D 1M47A 1F45B 2Z3QA 5C4XD 2LAGA 3BPNA 4BXXD 4A3MD 2KZ1A 3QB1A 3HOZD 1YKBA 1INRA 2Q14A 3DI3A 3H3VE 1HZIA 1EERA 3I4MD 1Z92A 2JA5D 1ITIA 5C44D 1BP3A 3EW3A 3BPOA 5FLMD 1M48A 2HYMB 2B8YA 5L6YC 4O9HA 5LQBA 3INKC 5C7XA 3PO2D 1WCMD 3B5KA 1BBNA 1ITMA 1M4CA 1Y6NL 2D9QA 3N06A 4A3BD 1M4RA 2O27A 5KNHI 1Z7CA 1Y1VD 5D22A 2IL6A 1M4AA 3LB6B 2O26A 2VUMD 1GNCA 4NN5A 3OQ3A 1CN4C 2B8UA 2E9WC 3SE4B 1RCBA 1BCNA 3HMXB 5IYDD 1D9CA 4A3LD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3M D;  3HOZ D;  5C3E D;  3H3V E;  2B63 D;  4A93 D;  3I4M D;  5IP7 D;  3FKI D;  2JA5 D;  3HOY D;  5C44 D;  3HOU D;  4A3J D;  1Y1W D;  4A3D D;  5FLM D;  5IYB D;  4BBS D;  3PO2 D;  1WCM D;  4A3F D;  4A3C D;  3I4N D;  2R7Z D;  4A3B D;  3AYH A;  2R93 D;  5IP9 D;  4BY7 D;  1Y1V D;  4A3G D;  3H0G D;  2JA7 D;  2C35 A;  4BBR D;  5IYC D;  3PO3 D;  3HOW D;  3HOX D;  2VUM D;  2R92 D;  2JA8 D;  4A3I D;  4A3K D;  4A3E D;  2JA6 D;  4BY1 D;  3HOV D;  1Y14 A;  5IYD D;  5C4X D;  4A3L D;  4BXX D; 
#chains in the Genus database with same CATH topology
 1CD9 A;  1PY2 A;  3FKI D;  5EQG A;  3UF5 A;  1EXZ A;  4ZW9 A;  2B8X A;  1ITF A;  1HUL A;  5IP9 D;  1RFB A;  2CFP A;  2L3Y A;  3EJJ A;  4YB9 D;  4NEJ A;  2ILK A;  2PSM A;  3DUH C;  1FG9 A;  3G6D A;  1IK0 A;  4JR9 A;  4DKC A;  4NEM A;  5GXB A;  5C3E D;  3LB6 A;  1HGU A;  4NN6 A;  4Q65 A;  5D71 A;  3D85 C;  3D87 A;  5A2N A;  3NPZ A;  1BGE A;  3O7P A;  1V7M V;  4YPG C;  4ZYR A;  1IAR A;  4PS4 A;  1AU1 A;  5EQI A;  3PIV A;  2ERJ D;  3VA2 A;  1ALU A;  1PV7 A;  2B5I A;  4QIQ A;  4Z5R D;  4IKY A;  3HHC A;  4IKW A;  4D2D A;  3BES L;  3I4N D;  3AYH A;  3OG4 A;  1HWH A;  4BY7 D;  2CFQ A;  4WRL B;  2XUT A;  1CNT 1;  3OG6 A;  4I77 Z;  2JA6 D;  1F45 B;  3BPN A;  4BXX D;  3QB1 A;  4XNJ A;  1HZI A;  1ITI A;  2JA5 D;  3BPO A;  3INK C;  5C7X A;  1WCM D;  1BBN A;  1ITM A;  1Y6N L;  4A3B D;  5C65 A;  4IU9 A;  2IL6 A;  3LB6 B;  2O26 A;  4NN5 A;  5A2O A;  1RCB A;  1BCN A;  3HMX B;  4A3L D;  2O6I A;  1HIJ A;  1PW4 A;  4GBZ A;  1CSG A;  4DKD A;  2LMS A;  4GC0 A;  4EXP A;  3HOU D;  4A3D D;  4DKF A;  2L3O A;  2B90 A;  2INT A;  1Y6M L;  4BBR D;  1IJZ A;  4NN7 A;  1PW6 A;  3PO3 D;  2R92 D;  2JA8 D;  1ITL A;  3HOV D;  4BY1 D;  1A7M A;  1WU3 I;  4U4T A;  4JRE A;  1EVS A;  5EQH A;  4GRW A;  1ILK A;  4BBS D;  1HIK A;  2CYK A;  1B5L A;  1LKI A;  1D9G A;  1SCF A;  2C35 A;  4X51 A;  3DI2 A;  4A3E D;  4ZWC A;  1IRL A;  4PYP A;  4XNI A;  1NBP A;  1PVH B;  4J05 A;  3WDO A;  3UX9 A;  3Q1S I;  4D2B A;  4A3F D;  4YBQ A;  4NKQ C;  5D28 B;  2Q7N B;  2H24 A;  3DLQ I;  3HHR A;  3NCB A;  3QT2 C;  1PGR A;  5IYC D;  3DGC L;  1AXI A;  4YQX A;  2Z3R A;  5D6K A;  2Z3Q A;  4W6V A;  2KZ1 A;  1YKB A;  3DI3 A;  3H3V E;  5C44 D;  5FLM D;  1M48 A;  2B8Y A;  1M4C A;  4IKV A;  5KNH I;  1Z7C A;  1Y1V D;  5D22 A;  4UVM A;  1GNC A;  4LEP A;  2E9W C;  1RW5 A;  3NCF A;  1P9M B;  4DOH A;  4GBY A;  2OQP A;  4NI9 A;  5D72 A;  1Y6K L;  2JA7 D;  1AX8 A;  1EKU A;  3NCC A;  3G9V B;  4YDY I;  3UF2 A;  3SE3 B;  4TPH A;  2V8N A;  3H0G D;  4CNI C;  2B91 A;  2B63 D;  3UEZ E;  1Y1W D;  1EMR A;  4FA8 E;  1V7N V;  1ETE A;  4TPJ A;  4ZWB A;  1FYH A;  3BPL A;  2Y5Y A;  4ZS7 A;  1I1R B;  4A3K D;  4RS1 A;  1LK3 A;  4A93 D;  2D48 A;  4YUE C;  3QB7 A;  4IKZ A;  2R93 D;  5D70 A;  4OH3 A;  1VLK A;  4O6K A;  3HOX D;  3D48 P;  4A3I D;  1QVN A;  1J7V L;  1M47 A;  5C4X D;  2LAG A;  3HOZ D;  4TPG A;  4U4V A;  1Z92 A;  3EW3 A;  2HYM B;  5L6Y C;  5LQB A;  3N06 A;  2D9Q A;  4U4W A;  2O27 A;  1M4A A;  2VUM D;  3OQ3 A;  4IKX A;  1CN4 C;  2B8U A;  5IYD D;  1D9C A;  2B8Z A;  5D59 A;  1BGD A;  1M4B A;  4A3J D;  5E4E A;  4ZF7 A;  1HUW A;  4D2C A;  3PIW A;  5FHX A;  4NI7 A;  4A3C D;  3IRH A;  1CYL A;  3NCE A;  4EXN A;  2Q98 A;  3O7Q A;  3HOW D;  3L5X A;  4LDS A;  1PV6 A;  3QAZ A;  5TS9 A;  1Y14 A;  1GA3 A;  1IL6 A;  3N0P A;  5IP7 D;  3HOY D;  1JLI A;  1KF9 A;  1A22 A;  4GS7 A;  2GMF A;  1BGC A;  2R7Z D;  3MZG A;  4OAA A;  3L5W I;  4A3G D;  4MHL A;  1HWG A;  3S9D A;  4LRL A;  4IU8 A;  1LQS L;  1BUY A;  4J4L C;  1RHG A;  5D58 A;  1N1F A;  3QWR B;  5FUC A;  1F6F A;  5IYB D;  3TGX B;  4DKE A;  1M49 A;  3WCY I;  2XQB A;  4A3M D;  1INR A;  2Q14 A;  1EER A;  3I4M D;  1BP3 A;  4O9H A;  3PO2 D;  3B5K A;  4APS A;  1M4R A;  4JA3 A;  3SE4 B; 
#chains in the Genus database with same CATH homology
 2O6I A;  1RW5 A;  1HIJ A;  2B8Z A;  1CD9 A;  1CSG A;  1P9M B;  1BGD A;  3NCF A;  1PY2 A;  3FKI D;  1M4B A;  2LMS A;  4DKD A;  4EXP A;  3HOU D;  3UF5 A;  1EXZ A;  4A3J D;  5E4E A;  4A3D D;  4DOH A;  4ZF7 A;  1HUW A;  3PIW A;  5FHX A;  4NI7 A;  2B8X A;  4A3C D;  3IRH A;  1ITF A;  1HUL A;  4DKF A;  2OQP A;  4NI9 A;  5IP9 D;  5D72 A;  1RFB A;  2L3O A;  1CYL A;  2B90 A;  2INT A;  3NCE A;  1Y6K L;  2L3Y A;  3EJJ A;  1AX8 A;  1Y6M L;  4EXN A;  2JA7 D;  2Q98 A;  2ILK A;  4NEJ A;  1IJZ A;  1EKU A;  2PSM A;  1PW6 A;  3DUH C;  3NCC A;  4NN7 A;  4BBR D;  3HOW D;  3PO3 D;  3G9V B;  2R92 D;  1FG9 A;  3G6D A;  3L5X A;  4YDY I;  2JA8 D;  1IK0 A;  3UF2 A;  1ITL A;  3QAZ A;  3SE3 B;  5TS9 A;  4DKC A;  3HOV D;  4NEM A;  1Y14 A;  4BY1 D;  3H0G D;  1GA3 A;  1A7M A;  1IL6 A;  1WU3 I;  4CNI C;  5C3E D;  2B91 A;  3LB6 A;  3N0P A;  1EVS A;  2B63 D;  5IP7 D;  3HOY D;  1JLI A;  4GRW A;  1ILK A;  1HGU A;  1KF9 A;  1A22 A;  3UEZ E;  4GS7 A;  1Y1W D;  1EMR A;  4NN6 A;  2GMF A;  4FA8 E;  5D71 A;  1V7N V;  1HIK A;  3D85 C;  3D87 A;  4BBS D;  3NPZ A;  1BGE A;  2CYK A;  1B5L A;  1LKI A;  1BGC A;  2R7Z D;  1D9G A;  3MZG A;  1ETE A;  1SCF A;  3L5W I;  1FYH A;  3BPL A;  4A3G D;  4MHL A;  2C35 A;  1HWG A;  4ZS7 A;  1V7M V;  4YPG C;  1IAR A;  3S9D A;  4X51 A;  4PS4 A;  3DI2 A;  1I1R B;  4LRL A;  4A3K D;  1AU1 A;  1LQS L;  4A3E D;  1IRL A;  3PIV A;  2ERJ D;  1BUY A;  4J4L C;  3VA2 A;  1ALU A;  4RS1 A;  1RHG A;  2B5I A;  4Z5R D;  1NBP A;  1LK3 A;  4A93 D;  1N1F A;  2D48 A;  3QWR B;  5FUC A;  1PVH B;  4YUE C;  1F6F A;  3HHC A;  3TGX B;  3UX9 A;  3Q1S I;  3QB7 A;  5IYB D;  4A3F D;  3BES L;  4NKQ C;  3I4N D;  3AYH A;  5D28 B;  3OG4 A;  2Q7N B;  2R93 D;  4DKE A;  1HWH A;  2H24 A;  3DLQ I;  5D70 A;  4BY7 D;  4WRL B;  3HHR A;  3NCB A;  1VLK A;  3OG6 A;  1CNT 1;  1PGR A;  3QT2 C;  5IYC D;  3DGC L;  1AXI A;  4YQX A;  4O6K A;  3HOX D;  2Z3R A;  1M49 A;  3D48 P;  4A3I D;  3WCY I;  4I77 Z;  2XQB A;  1QVN A;  1J7V L;  2JA6 D;  1M47 A;  1F45 B;  2Z3Q A;  5C4X D;  2LAG A;  3BPN A;  4BXX D;  4A3M D;  2KZ1 A;  3QB1 A;  3HOZ D;  1YKB A;  1INR A;  2Q14 A;  3DI3 A;  3H3V E;  1HZI A;  1EER A;  3I4M D;  1Z92 A;  2JA5 D;  1ITI A;  5C44 D;  1BP3 A;  3EW3 A;  3BPO A;  5FLM D;  1M48 A;  2HYM B;  2B8Y A;  5L6Y C;  4O9H A;  5LQB A;  3INK C;  5C7X A;  3PO2 D;  1WCM D;  3B5K A;  1BBN A;  1ITM A;  1M4C A;  1Y6N L;  2D9Q A;  3N06 A;  4A3B D;  1M4R A;  2O27 A;  5KNH I;  1Z7C A;  1Y1V D;  5D22 A;  2IL6 A;  1M4A A;  3LB6 B;  2O26 A;  2VUM D;  1GNC A;  4NN5 A;  3OQ3 A;  1CN4 C;  2B8U A;  2E9W C;  3SE4 B;  1RCB A;  1BCN A;  3HMX B;  5IYD D;  1D9C A;  4A3L D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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