4YBQA

Rat glut5 with fv in the outward-open form
Total Genus 191
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
191
sequence length
474
structure length
452
Chain Sequence
EKTGKLTLVLALATFLAAFGSSFQYGYNVAAVIESFTLTLLWSLTVSMFPFGGFIGSLMVGFLVNNLGRKGALLFNNIFSILPAILMGCSKIAKSFEIIIASRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFGLRSVLASEEGWPILLGLTGVPAGLQLLLLPFFPESPRYLLIQKKNESAAEKALQTLRGWKDVDMEMEEIRKEDEAEKAAGFISVWKLFRMQSLRWQLISTIVLMAGQQLSGVNAIYYYADQIYLSAGVKSNDVQYVTAGTGAVNVFMTMVTVFVVELWGRRNLLLIGFSTCLTACIVLTVALALQNTISWMPYVSIVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIGGSVHWLSNFIVGLIFPFIQVGLGPYSFIIFAIICLLTTIYIFMVVPETKGRTFVEINQIFAKKNKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of the mammalian fructose transporter GLUT5
pubmed doi rcsb
molecule keywords Solute carrier family 2, facilitated glucose transporter mem
molecule tags Transport protein/immune system
source organism Rattus norvegicus
total genus 191
structure length 452
sequence length 474
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ybqA00
1PW4A 1PV6A 4OH3A 3WDOA 5GXBA 2Y5YA 4IKVA 4JR9A 4IKWA 4ZYRA 4W6VA 4J05A 3O7PA 4TPGA 3O7QA 4ZW9A 4IKXA 4U4VA 5EQGA 4JREA 4LEPA 4ZWBA 5D59A 4PYPA 4TPHA 4U4TA 4YB9D 4UVMA 4APSA 2CFQA 5C65A 4GBYA 4QIQA 4XNJA 2XUTA 4XNIA 4IU9A 5D6KA 4IKYA 2V8NA 4IU8A 5EQHA 4D2DA 4OAAA 5A2NA 4YBQA 4U4WA 4GC0A 4D2CA 5A2OA 4LDSA 4Q65A 4ZWCA 4TPJA 1PV7A 4JA3A 4D2BA 4IKZA 5D58A 2CFPA 4GBZA 5EQIA
chains in the Genus database with same CATH superfamily
2Z3RA 1I1RB 4DKFA 4IKVA 1EMRA 2PSMA 2D9QA 4FA8E 4ZWBA 4TPHA 5D28B 1ITMA 4APSA 4GBYA 4O6KA 2HYMB 2LAGA 4A3ED 1BP3A 3FKID 3DI3A 1Y1VD 1PV6A 3WDOA 3HHCA 3S9DA 5IYDD 1INRA 1IRLA 3I4ND 3BPLA 4QIQA 5IYCD 1Z7CA 5C7XA 5EQHA 2JA7D 2XQBA 1BCNA 4Q65A 3EJJA 1IL6A 2ILKA 4PYPA 1M4BA 3NCFA 3WCYI 1Z92A 1M4CA 4YB9D 4X51A 4IU9A 5KNHI 3UX9A 4D2DA 4OAAA 3LB6A 2Q7NB 2B8UA 4OH3A 1EERA 3HOUD 3N06A 4U4VA 3HOZD 3L5XA 4NEJA 1RCBA 4A3MD 2B90A 1Y6NL 4NN6A 1EKUA 2D48A 2L3YA 4NI9A 1FYHA 3BPOA 2L3OA 1EXZA 4U4WA 1CN4C 3NPZA 5D58A 4GRWA 1EVSA 2KZ1A 1BGDA 2IL6A 3D48P 4JR9A 5E4EA 3UF2A 2Q98A 2JA6D 2Z3QA 1Y6KL 4A3CD 2R92D 1IJZA 3DLQI 1IARA 4UVMA 1N1FA 1ITFA 2H24A 3QB1A 4GS7A 3BESL 3VA2A 1IK0A 1D9GA 2CFPA 2B8XA 4JA3A 1Y1WD 4BY7D 4J05A 4TPGA 5D22A 1ILKA 5IYBD 4DKCA 4YQXA 1HUWA 1GNCA 1ITIA 1ALUA 2B5IA 4Z5RD 3B5KA 1M48A 4YUEC 1BGCA 4D2BA 4A3DD 4DKDA 1VLKA 1HIKA 4NN7A 4NKQC 3HHRA 4IKXA 3HOXD 1WCMD 1Y6ML 4IU8A 3DGCL 4YBQA 4GC0A 1HIJA 1V7MV 5EQIA 3D87A 3DUHC 4EXNA 3I4MD 2B63D 3DI2A 4DKEA 5LQBA 1Y14A 3QT2C 4A93D 3QWRB 4LRLA 3H3VE 5EQGA 4A3LD 5FUCA 3IRHA 4ZS7A 3D85C 3UEZE 1PVHB 2C35A 1P9MB 3EW3A 1HULA 4ZF7A 1B5LA 1F6FA 1F45B 5D59A 4U4TA 4A3GD 3NCEA 1A7MA 2R93D 1ETEA 3OG4A 1AU1A 4D2CA 4RS1A 5A2OA 4ZWCA 5D70A 3MZGA 1CYLA 1HWHA 2INTA 3SE3B 3OQ3A 1PW6A 3NCCA 4A3FD 4I77Z 5TS9A 1CSGA 2E9WC 4A3KD 1QVNA 5FHXA 3Q1SI 3TGXB 2O27A 2O26A 3L5WI 4TPJA 1RFBA 1M4AA 3SE4B 4CNIC 4GBZA 1ITLA 5IP7D 3G6DA 5C4XD 1SCFA 1CNT1 1HGUA 3PO3D 5C65A 1AXIA 3BPNA 2B8YA 1D9CA 3HOYD 2B91A 1JLIA 5A2NA 1PY2A 4A3BD 2R7ZD 4J4LC 5IP9D 4BXXD 1CD9A 1BGEA 1PGRA 4YPGC 2CFQA 4XNIA 1LQSL 5L6YC 1V7NV 4BBRD 2JA5D 4LDSA 3H0GD 4BY1D 4IKWA 4W6VA 4WRLB 4NN5A 4ZW9A 2Q14A 3N0PA 1AX8A 2LMSA 1WU3I 4NEMA 4IKYA 3G9VB 4A3JD 3HMXB 1LK3A 2O6IA 2GMFA 1NBPA 1KF9A 4O9HA 3HOVD 4LEPA 1M4RA 3NCBA 1GA3A 4XNJA 3AYHA 4DOHA 1J7VL 5C3ED 3QB7A 2B8ZA 1HWGA 5GXBA 2Y5YA 1M49A 4ZYRA 2CYKA 1M47A 4EXPA 3O7PA 3O7QA 3INKC 3PIVA 2VUMD 1BBNA 3PIWA 1RHGA 1LKIA 2XUTA 5D6KA 1BUYA 2V8NA 4BBSD 1A22A 5FLMD 4MHLA 2ERJD 1RW5A 4YDYI 3OG6A 4PS4A 3HOWD 4IKZA 5C44D 1PW4A 3LB6B 3UF5A 1HZIA 3QAZA 5D71A 1FG9A 1YKBA 4JREA 2JA8D 4NI7A 2OQPA 4A3ID 5D72A 3PO2D 1PV7A
chains in the Genus database with same CATH topology
1PW4A 1PV6A 4OH3A 3WDOA 5GXBA 2Y5YA 4IKVA 4JR9A 4IKWA 4ZYRA 4W6VA 4J05A 3O7PA 4TPGA 3O7QA 4ZW9A 4IKXA 4U4VA 5EQGA 4JREA 4LEPA 4ZWBA 5D59A 4PYPA 4TPHA 4U4TA 4YB9D 4UVMA 4APSA 2CFQA 5C65A 4GBYA 4QIQA 4XNJA 2XUTA 4XNIA 4IU9A 5D6KA 4IKYA 2V8NA 4IU8A 5EQHA 4D2DA 4OAAA 5A2NA 4YBQA 4U4WA 4GC0A 4D2CA 5A2OA 4LDSA 4Q65A 4ZWCA 4TPJA 1PV7A 4JA3A 4D2BA 4IKZA 5D58A 2CFPA 4GBZA 5EQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PW4 A;  1PV6 A;  4OH3 A;  3WDO A;  5GXB A;  2Y5Y A;  4IKV A;  4JR9 A;  4IKW A;  4ZYR A;  4W6V A;  4J05 A;  3O7P A;  4TPG A;  3O7Q A;  4ZW9 A;  4IKX A;  4U4V A;  5EQG A;  4JRE A;  4LEP A;  4ZWB A;  5D59 A;  4PYP A;  4TPH A;  4U4T A;  4YB9 D;  4UVM A;  4APS A;  2CFQ A;  5C65 A;  4GBY A;  4QIQ A;  4XNJ A;  2XUT A;  4XNI A;  4IU9 A;  5D6K A;  4IKY A;  2V8N A;  4IU8 A;  5EQH A;  4D2D A;  4OAA A;  5A2N A;  4YBQ A;  4U4W A;  4GC0 A;  4D2C A;  5A2O A;  4LDS A;  4Q65 A;  4ZWC A;  4TPJ A;  1PV7 A;  4JA3 A;  4D2B A;  4IKZ A;  5D58 A;  2CFP A;  4GBZ A;  5EQI A; 
#chains in the Genus database with same CATH topology
 2Z3R A;  1I1R B;  4DKF A;  4IKV A;  1EMR A;  2PSM A;  2D9Q A;  4FA8 E;  4ZWB A;  4TPH A;  5D28 B;  1ITM A;  4APS A;  4GBY A;  4O6K A;  2HYM B;  2LAG A;  4A3E D;  1BP3 A;  3FKI D;  3DI3 A;  1Y1V D;  1PV6 A;  3WDO A;  3HHC A;  3S9D A;  5IYD D;  1INR A;  1IRL A;  3I4N D;  3BPL A;  4QIQ A;  5IYC D;  1Z7C A;  5C7X A;  5EQH A;  2JA7 D;  2XQB A;  1BCN A;  4Q65 A;  3EJJ A;  1IL6 A;  2ILK A;  4PYP A;  1M4B A;  3NCF A;  3WCY I;  1Z92 A;  1M4C A;  4YB9 D;  4X51 A;  4IU9 A;  5KNH I;  3UX9 A;  4D2D A;  4OAA A;  3LB6 A;  2Q7N B;  2B8U A;  4OH3 A;  1EER A;  3HOU D;  3N06 A;  4U4V A;  3HOZ D;  3L5X A;  4NEJ A;  1RCB A;  4A3M D;  2B90 A;  1Y6N L;  4NN6 A;  1EKU A;  2D48 A;  2L3Y A;  4NI9 A;  1FYH A;  3BPO A;  2L3O A;  1EXZ A;  4U4W A;  1CN4 C;  3NPZ A;  5D58 A;  4GRW A;  1EVS A;  2KZ1 A;  1BGD A;  2IL6 A;  3D48 P;  4JR9 A;  5E4E A;  3UF2 A;  2Q98 A;  2JA6 D;  2Z3Q A;  1Y6K L;  4A3C D;  2R92 D;  1IJZ A;  3DLQ I;  1IAR A;  4UVM A;  1N1F A;  1ITF A;  2H24 A;  3QB1 A;  4GS7 A;  3BES L;  3VA2 A;  1IK0 A;  1D9G A;  2CFP A;  2B8X A;  4JA3 A;  1Y1W D;  4BY7 D;  4J05 A;  4TPG A;  5D22 A;  1ILK A;  5IYB D;  4DKC A;  4YQX A;  1HUW A;  1GNC A;  1ITI A;  1ALU A;  2B5I A;  4Z5R D;  3B5K A;  1M48 A;  4YUE C;  1BGC A;  4D2B A;  4A3D D;  4DKD A;  1VLK A;  1HIK A;  4NN7 A;  4NKQ C;  3HHR A;  4IKX A;  3HOX D;  1WCM D;  1Y6M L;  4IU8 A;  3DGC L;  4YBQ A;  4GC0 A;  1HIJ A;  1V7M V;  5EQI A;  3D87 A;  3DUH C;  4EXN A;  3I4M D;  2B63 D;  3DI2 A;  4DKE A;  5LQB A;  1Y14 A;  3QT2 C;  4A93 D;  3QWR B;  4LRL A;  3H3V E;  5EQG A;  4A3L D;  5FUC A;  3IRH A;  4ZS7 A;  3D85 C;  3UEZ E;  1PVH B;  2C35 A;  1P9M B;  3EW3 A;  1HUL A;  4ZF7 A;  1B5L A;  1F6F A;  1F45 B;  5D59 A;  4U4T A;  4A3G D;  3NCE A;  1A7M A;  2R93 D;  1ETE A;  3OG4 A;  1AU1 A;  4D2C A;  4RS1 A;  5A2O A;  4ZWC A;  5D70 A;  3MZG A;  1CYL A;  1HWH A;  2INT A;  3SE3 B;  3OQ3 A;  1PW6 A;  3NCC A;  4A3F D;  4I77 Z;  5TS9 A;  1CSG A;  2E9W C;  4A3K D;  1QVN A;  5FHX A;  3Q1S I;  3TGX B;  2O27 A;  2O26 A;  3L5W I;  4TPJ A;  1RFB A;  1M4A A;  3SE4 B;  4CNI C;  4GBZ A;  1ITL A;  5IP7 D;  3G6D A;  5C4X D;  1SCF A;  1CNT 1;  1HGU A;  3PO3 D;  5C65 A;  1AXI A;  3BPN A;  2B8Y A;  1D9C A;  3HOY D;  2B91 A;  1JLI A;  5A2N A;  1PY2 A;  4A3B D;  2R7Z D;  4J4L C;  5IP9 D;  4BXX D;  1CD9 A;  1BGE A;  1PGR A;  4YPG C;  2CFQ A;  4XNI A;  1LQS L;  5L6Y C;  1V7N V;  4BBR D;  2JA5 D;  4LDS A;  3H0G D;  4BY1 D;  4IKW A;  4W6V A;  4WRL B;  4NN5 A;  4ZW9 A;  2Q14 A;  3N0P A;  1AX8 A;  2LMS A;  1WU3 I;  4NEM A;  4IKY A;  3G9V B;  4A3J D;  3HMX B;  1LK3 A;  2O6I A;  2GMF A;  1NBP A;  1KF9 A;  4O9H A;  3HOV D;  4LEP A;  1M4R A;  3NCB A;  1GA3 A;  4XNJ A;  3AYH A;  4DOH A;  1J7V L;  5C3E D;  3QB7 A;  2B8Z A;  1HWG A;  5GXB A;  2Y5Y A;  1M49 A;  4ZYR A;  2CYK A;  1M47 A;  4EXP A;  3O7P A;  3O7Q A;  3INK C;  3PIV A;  2VUM D;  1BBN A;  3PIW A;  1RHG A;  1LKI A;  2XUT A;  5D6K A;  1BUY A;  2V8N A;  4BBS D;  1A22 A;  5FLM D;  4MHL A;  2ERJ D;  1RW5 A;  4YDY I;  3OG6 A;  4PS4 A;  3HOW D;  4IKZ A;  5C44 D;  1PW4 A;  3LB6 B;  3UF5 A;  1HZI A;  3QAZ A;  5D71 A;  1FG9 A;  1YKB A;  4JRE A;  2JA8 D;  4NI7 A;  2OQP A;  4A3I D;  5D72 A;  3PO2 D;  1PV7 A; 
#chains in the Genus database with same CATH homology
 1PW4 A;  1PV6 A;  4OH3 A;  3WDO A;  5GXB A;  2Y5Y A;  4IKV A;  4JR9 A;  4IKW A;  4ZYR A;  4W6V A;  4J05 A;  3O7P A;  4TPG A;  3O7Q A;  4ZW9 A;  4IKX A;  4U4V A;  5EQG A;  4JRE A;  4LEP A;  4ZWB A;  5D59 A;  4PYP A;  4TPH A;  4U4T A;  4YB9 D;  4UVM A;  4APS A;  2CFQ A;  5C65 A;  4GBY A;  4QIQ A;  4XNJ A;  2XUT A;  4XNI A;  4IU9 A;  5D6K A;  4IKY A;  2V8N A;  4IU8 A;  5EQH A;  4D2D A;  4OAA A;  5A2N A;  4YBQ A;  4U4W A;  4GC0 A;  4D2C A;  5A2O A;  4LDS A;  4Q65 A;  4ZWC A;  4TPJ A;  1PV7 A;  4JA3 A;  4D2B A;  4IKZ A;  5D58 A;  2CFP A;  4GBZ A;  5EQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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