2CFQA

Sugar free lactose permease at neutral ph
Total Genus 115
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
417
structure length
417
Chain Sequence
b'MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALGASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords LACTOSE PERMEASE
publication title Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transport
total genus 115
structure length 417
sequence length 417
ec nomenclature
pdb deposition date 2006-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01306 LacY_symp LacY proton/sugar symporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 2cfqA02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 2cfqA01
4ZW9A 1PW4A 4YBQA 4UVMA 4TPGA 1PV7A 5D58A 2XUTA 5C65A 3WDOA 5A2NA 5A2OA 4IKXA 4GBYA 2Y5YA 4ZWBA 4IU8A 4IKYA 4GBZA 4JA3A 3O7PA 4OH3A 4U4WA 4XNJA 4YB9D 2V8NA 4LDSA 5EQIA 4APSA 5D59A 4QIQA 4W6VA 4Q65A 4GC0A 4U4VA 4XNIA 4D2CA 4IU9A 5EQHA 4U4TA 4TPHA 4PYPA 4JR9A 4JREA 4LEPA 5D6KA 4D2BA 5EQGA 1PV6A 4J05A 4IKWA 4OAAA 5GXBA 4IKZA 4TPJA 4D2DA 4ZYRA 3O7QA 2CFPA 2CFQA 4ZWCA 4IKVA
chains in the Genus database with same CATH superfamily
4GBZA 1B5LA 2HYMB 3NCBA 2R7ZD 1HUWA 2L3YA 5L6YC 1M48A 3BESL 4JR9A 4NEJA 4PYPA 3H0GD 5D6KA 2LMSA 4D2DA 3L5XA 5FUCA 3HOWD 5EQIA 1BUYA 3TGXB 4I77Z 1RW5A 4ZW9A 5IYDD 2Q7NB 1I1RB 2D9QA 3HOVD 2V8NA 1CNT1 2ERJD 3NCEA 2B90A 4LRLA 1LQSL 2OQPA 1Y1WD 1LK3A 1PV6A 4BXXD 5IP9D 3SE3B 1RCBA 1IL6A 5LQBA 4TPGA 3UEZE 5D22A 3WDOA 1BGEA 3UX9A 1QVNA 1RHGA 3DLQI 4A3DD 2CYKA 1KF9A 1M4CA 1YKBA 4A3JD 3OG4A 4DKEA 4A3BD 3DGCL 1BGDA 4ZYRA 3HOUD 2JA6D 1AX8A 1RFBA 2Y5YA 3WCYI 4IKYA 3B5KA 3D48P 1EVSA 1Z7CA 1JLIA 1A7MA 1PY2A 2LAGA 4LEPA 1D9CA 2KZ1A 4A3CD 2O26A 1GNCA 5IYCD 5D28B 3G6DA 1HWGA 2B8YA 1M4BA 5A2OA 4A3KD 2C35A 4XNJA 4BBRD 2L3OA 1ALUA 3HOXD 1Z92A 3DUHC 2ILKA 4O6KA 4YDYI 1M4AA 3FKID 4PS4A 2CFQA 3BPNA 1PW4A 1ITIA 1PGRA 1IJZA 1EERA 3I4ND 3EW3A 4WRLB 2JA5D 5C44D 5IP7D 4DKDA 1SCFA 4A93D 3UF2A 1Y1VD 4NN7A 4A3GD 5TS9A 5KNHI 5D58A 3HOYD 4CNIC 2XQBA 2B8UA 4RS1A 1CD9A 1FG9A 5FLMD 3PO2D 1EKUA 2R93D 2B5IA 1INRA 4BBSD 1VLKA 1PW6A 1ITMA 1F45B 4NN5A 4O9HA 3QB7A 5C3ED 3QWRB 2H24A 3HHRA 1ITLA 4YB9D 3LB6B 4ZF7A 4DKCA 3IRHA 3NCFA 4IKWA 1HZIA 2E9WC 1NBPA 1WU3I 3L5WI 4GRWA 4BY1D 4YPGC 1ITFA 4IKXA 5C4XD 4JA3A 4OH3A 4NI7A 1IK0A 4LDSA 4APSA 3PIWA 2Z3RA 4Q65A 4NEMA 1BP3A 4XNIA 4IU9A 4FA8E 3PIVA 4DOHA 2CFPA 3D87A 4YBQA 3HOZD 4UVMA 3G9VB 4MHLA 3O7PA 2O6IA 2Z3QA 5D59A 3OG6A 3Q1SI 1F6FA 3QT2C 3S9DA 5E4EA 1J7VL 2B8XA 2GMFA 1PV7A 3HHCA 3H3VE 4QIQA 5D70A 1ILKA 4A3ID 5IYBD 3D85C 3QAZA 3HMXB 2INTA 1HIKA 5EQGA 3INKC 1BBNA 4ZWCA 4A3FD 4A3ED 4ZWBA 3NPZA 3N0PA 1Y6NL 4YUEC 5EQHA 1BGCA 2JA8D 4D2BA 2B8ZA 4NKQC 1IRLA 1Y6ML 4GS7A 4IKVA 4J4LC 1EMRA 5D72A 1AXIA 1HWHA 2Q14A 4IU8A 3UF5A 4A3MD 4U4WA 2VUMD 2O27A 4W6VA 1HIJA 2IL6A 3BPLA 1AU1A 1Y14A 4D2CA 5D71A 3EJJA 4U4TA 4YQXA 5C7XA 1HULA 3SE4B 4J05A 1M49A 4TPJA 1M47A 1CN4C 3NCCA 5FHXA 3I4MD 4NI9A 5A2NA 1FYHA 3BPOA 4GBYA 2R92D 1CSGA 1Y6KL 3DI3A 3DI2A 2Q98A 1IARA 4EXPA 4GC0A 1HGUA 1V7NV 1N1FA 2D48A 1BCNA 1M4RA 4ZS7A 4BY7D 4Z5RD 4A3LD 4NN6A 5C65A 4X51A 3PO3D 1CYLA 1GA3A 2B91A 4TPHA 4OAAA 1A22A 5GXBA 4IKZA 1EXZA 3O7QA 4EXNA 2B63D 1P9MB 2XUTA 4DKFA 3VA2A 1LKIA 1D9GA 3OQ3A 1V7MV 4U4VA 3AYHA 1WCMD 2PSMA 1ETEA 2JA7D 4JREA 3LB6A 3N06A 3QB1A 1PVHB 3MZGA
chains in the Genus database with same CATH topology
4ZW9A 1PW4A 4YBQA 4UVMA 4TPGA 1PV7A 5D58A 2XUTA 5C65A 3WDOA 5A2NA 5A2OA 4IKXA 4GBYA 2Y5YA 4ZWBA 4IU8A 4IKYA 4GBZA 4JA3A 3O7PA 4OH3A 4U4WA 4XNJA 4YB9D 2V8NA 4LDSA 5EQIA 4APSA 5D59A 4QIQA 4W6VA 4Q65A 4GC0A 4U4VA 4XNIA 4D2CA 4IU9A 5EQHA 4U4TA 4TPHA 4PYPA 4JR9A 4JREA 4LEPA 5D6KA 4D2BA 5EQGA 1PV6A 4J05A 4IKWA 4OAAA 5GXBA 4IKZA 4TPJA 4D2DA 4ZYRA 3O7QA 2CFPA 2CFQA 4ZWCA 4IKVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZW9 A;  1PW4 A;  4YBQ A;  4UVM A;  4TPG A;  1PV7 A;  5D58 A;  2XUT A;  5C65 A;  3WDO A;  5A2N A;  5A2O A;  4IKX A;  4GBY A;  2Y5Y A;  4ZWB A;  4IU8 A;  4IKY A;  4GBZ A;  4JA3 A;  3O7P A;  4OH3 A;  4U4W A;  4XNJ A;  4YB9 D;  2V8N A;  4LDS A;  5EQI A;  4APS A;  5D59 A;  4QIQ A;  4W6V A;  4Q65 A;  4GC0 A;  4U4V A;  4XNI A;  4D2C A;  4IU9 A;  5EQH A;  4U4T A;  4TPH A;  4PYP A;  4JR9 A;  4JRE A;  4LEP A;  5D6K A;  4D2B A;  5EQG A;  1PV6 A;  4J05 A;  4IKW A;  4OAA A;  5GXB A;  4IKZ A;  4TPJ A;  4D2D A;  4ZYR A;  3O7Q A;  2CFP A;  2CFQ A;  4ZWC A;  4IKV A; 
#chains in the Genus database with same CATH topology
 4GBZ A;  1B5L A;  2HYM B;  3NCB A;  2R7Z D;  1HUW A;  2L3Y A;  5L6Y C;  1M48 A;  3BES L;  4JR9 A;  4NEJ A;  4PYP A;  3H0G D;  5D6K A;  2LMS A;  4D2D A;  3L5X A;  5FUC A;  3HOW D;  5EQI A;  1BUY A;  3TGX B;  4I77 Z;  1RW5 A;  4ZW9 A;  5IYD D;  2Q7N B;  1I1R B;  2D9Q A;  3HOV D;  2V8N A;  1CNT 1;  2ERJ D;  3NCE A;  2B90 A;  4LRL A;  1LQS L;  2OQP A;  1Y1W D;  1LK3 A;  1PV6 A;  4BXX D;  5IP9 D;  3SE3 B;  1RCB A;  1IL6 A;  5LQB A;  4TPG A;  3UEZ E;  5D22 A;  3WDO A;  1BGE A;  3UX9 A;  1QVN A;  1RHG A;  3DLQ I;  4A3D D;  2CYK A;  1KF9 A;  1M4C A;  1YKB A;  4A3J D;  3OG4 A;  4DKE A;  4A3B D;  3DGC L;  1BGD A;  4ZYR A;  3HOU D;  2JA6 D;  1AX8 A;  1RFB A;  2Y5Y A;  3WCY I;  4IKY A;  3B5K A;  3D48 P;  1EVS A;  1Z7C A;  1JLI A;  1A7M A;  1PY2 A;  2LAG A;  4LEP A;  1D9C A;  2KZ1 A;  4A3C D;  2O26 A;  1GNC A;  5IYC D;  5D28 B;  3G6D A;  1HWG A;  2B8Y A;  1M4B A;  5A2O A;  4A3K D;  2C35 A;  4XNJ A;  4BBR D;  2L3O A;  1ALU A;  3HOX D;  1Z92 A;  3DUH C;  2ILK A;  4O6K A;  4YDY I;  1M4A A;  3FKI D;  4PS4 A;  2CFQ A;  3BPN A;  1PW4 A;  1ITI A;  1PGR A;  1IJZ A;  1EER A;  3I4N D;  3EW3 A;  4WRL B;  2JA5 D;  5C44 D;  5IP7 D;  4DKD A;  1SCF A;  4A93 D;  3UF2 A;  1Y1V D;  4NN7 A;  4A3G D;  5TS9 A;  5KNH I;  5D58 A;  3HOY D;  4CNI C;  2XQB A;  2B8U A;  4RS1 A;  1CD9 A;  1FG9 A;  5FLM D;  3PO2 D;  1EKU A;  2R93 D;  2B5I A;  1INR A;  4BBS D;  1VLK A;  1PW6 A;  1ITM A;  1F45 B;  4NN5 A;  4O9H A;  3QB7 A;  5C3E D;  3QWR B;  2H24 A;  3HHR A;  1ITL A;  4YB9 D;  3LB6 B;  4ZF7 A;  4DKC A;  3IRH A;  3NCF A;  4IKW A;  1HZI A;  2E9W C;  1NBP A;  1WU3 I;  3L5W I;  4GRW A;  4BY1 D;  4YPG C;  1ITF A;  4IKX A;  5C4X D;  4JA3 A;  4OH3 A;  4NI7 A;  1IK0 A;  4LDS A;  4APS A;  3PIW A;  2Z3R A;  4Q65 A;  4NEM A;  1BP3 A;  4XNI A;  4IU9 A;  4FA8 E;  3PIV A;  4DOH A;  2CFP A;  3D87 A;  4YBQ A;  3HOZ D;  4UVM A;  3G9V B;  4MHL A;  3O7P A;  2O6I A;  2Z3Q A;  5D59 A;  3OG6 A;  3Q1S I;  1F6F A;  3QT2 C;  3S9D A;  5E4E A;  1J7V L;  2B8X A;  2GMF A;  1PV7 A;  3HHC A;  3H3V E;  4QIQ A;  5D70 A;  1ILK A;  4A3I D;  5IYB D;  3D85 C;  3QAZ A;  3HMX B;  2INT A;  1HIK A;  5EQG A;  3INK C;  1BBN A;  4ZWC A;  4A3F D;  4A3E D;  4ZWB A;  3NPZ A;  3N0P A;  1Y6N L;  4YUE C;  5EQH A;  1BGC A;  2JA8 D;  4D2B A;  2B8Z A;  4NKQ C;  1IRL A;  1Y6M L;  4GS7 A;  4IKV A;  4J4L C;  1EMR A;  5D72 A;  1AXI A;  1HWH A;  2Q14 A;  4IU8 A;  3UF5 A;  4A3M D;  4U4W A;  2VUM D;  2O27 A;  4W6V A;  1HIJ A;  2IL6 A;  3BPL A;  1AU1 A;  1Y14 A;  4D2C A;  5D71 A;  3EJJ A;  4U4T A;  4YQX A;  5C7X A;  1HUL A;  3SE4 B;  4J05 A;  1M49 A;  4TPJ A;  1M47 A;  1CN4 C;  3NCC A;  5FHX A;  3I4M D;  4NI9 A;  5A2N A;  1FYH A;  3BPO A;  4GBY A;  2R92 D;  1CSG A;  1Y6K L;  3DI3 A;  3DI2 A;  2Q98 A;  1IAR A;  4EXP A;  4GC0 A;  1HGU A;  1V7N V;  1N1F A;  2D48 A;  1BCN A;  1M4R A;  4ZS7 A;  4BY7 D;  4Z5R D;  4A3L D;  4NN6 A;  5C65 A;  4X51 A;  3PO3 D;  1CYL A;  1GA3 A;  2B91 A;  4TPH A;  4OAA A;  1A22 A;  5GXB A;  4IKZ A;  1EXZ A;  3O7Q A;  4EXN A;  2B63 D;  1P9M B;  2XUT A;  4DKF A;  3VA2 A;  1LKI A;  1D9G A;  3OQ3 A;  1V7M V;  4U4V A;  3AYH A;  1WCM D;  2PSM A;  1ETE A;  2JA7 D;  4JRE A;  3LB6 A;  3N06 A;  3QB1 A;  1PVH B;  3MZG A; 
#chains in the Genus database with same CATH homology
 4ZW9 A;  1PW4 A;  4YBQ A;  4UVM A;  4TPG A;  1PV7 A;  5D58 A;  2XUT A;  5C65 A;  3WDO A;  5A2N A;  5A2O A;  4IKX A;  4GBY A;  2Y5Y A;  4ZWB A;  4IU8 A;  4IKY A;  4GBZ A;  4JA3 A;  3O7P A;  4OH3 A;  4U4W A;  4XNJ A;  4YB9 D;  2V8N A;  4LDS A;  5EQI A;  4APS A;  5D59 A;  4QIQ A;  4W6V A;  4Q65 A;  4GC0 A;  4U4V A;  4XNI A;  4D2C A;  4IU9 A;  5EQH A;  4U4T A;  4TPH A;  4PYP A;  4JR9 A;  4JRE A;  4LEP A;  5D6K A;  4D2B A;  5EQG A;  1PV6 A;  4J05 A;  4IKW A;  4OAA A;  5GXB A;  4IKZ A;  4TPJ A;  4D2D A;  4ZYR A;  3O7Q A;  2CFP A;  2CFQ A;  4ZWC A;  4IKV A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...