1PV7A

Crystal structure of lactose permease with tdg
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
417
structure length
417
Chain Sequence
MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALGASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of the lactose permease of Escherichia coli
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords Lactose permease
total genus 144
structure length 417
sequence length 417
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01306 LacY_symp LacY proton/sugar symporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 1pv7A02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 1pv7A01
4IKZA 4JR9A 5A2OA 5EQIA 4YB9D 4IKXA 4XNIA 4IKVA 4D2CA 4Q65A 4D2DA 3O7PA 4IU8A 4U4VA 4U4TA 1PV6A 4TPGA 4LEPA 2Y5YA 4IU9A 2CFQA 4GBZA 4J05A 4W6VA 4UVMA 4JREA 4TPJA 4ZW9A 5A2NA 4IKYA 4ZYRA 4PYPA 5GXBA 4ZWBA 2CFPA 4APSA 4IKWA 5D59A 4GC0A 4OAAA 4U4WA 4LDSA 4OH3A 4QIQA 5D58A 4XNJA 3WDOA 4D2BA 4TPHA 2XUTA 4JA3A 1PV7A 2V8NA 5D6KA 5EQGA 5C65A 3O7QA 4YBQA 1PW4A 4ZWCA 4GBYA 5EQHA
chains in the Genus database with same CATH superfamily
2KZ1A 2D48A 5EQIA 4IKXA 2JA6D 1KF9A 4RS1A 2L3OA 1F6FA 4A3MD 1LK3A 2B91A 3H0GD 2PSMA 4IKYA 2CFPA 1BCNA 1ITFA 1QVNA 1BGCA 1M4AA 4DKFA 3PIVA 5C65A 4BY1D 3Q1SI 5LQBA 5E4EA 1D9GA 4DOHA 1EXZA 3HOYD 1CSGA 1HGUA 2IL6A 1IRLA 4YDYI 3HHCA 3G6DA 3PIWA 4NEJA 2O27A 3S9DA 1PGRA 4GBZA 3HOXD 1HWHA 1GNCA 1FG9A 3QB1A 1ETEA 4O6KA 2CYKA 4A3CD 3OQ3A 4NN6A 4NKQC 4PS4A 1IK0A 2B8UA 2L3YA 1Y1WD 4A3ID 5C3ED 1LQSL 1FYHA 2HYMB 1V7NV 4OH3A 4D2BA 5EQGA 5D72A 1YKBA 3TGXB 2R7ZD 4MHLA 1ALUA 3BPOA 1PV6A 1PW6A 2R92D 3D85C 2INTA 1IJZA 3BESL 1J7VL 2XUTA 1RW5A 1V7MV 4NI7A 5D28B 3DUHC 1CD9A 3IRHA 1Y6ML 3O7PA 1I1RB 5IYBD 1N1FA 3LB6B 4NN5A 5D58A 4A3FD 3QT2C 5TS9A 2B63D 3QWRB 5D71A 1EMRA 4A93D 3OG6A 1Z92A 4IKZA 5IYDD 3QB7A 5IP7D 4J4LC 2Q7NB 4ZYRA 4DKCA 3DI2A 1ITMA 1WCMD 5IP9D 2E9WC 4QIQA 3G9VB 2V8NA 3I4ND 1AU1A 1NBPA 4A3BD 3DGCL 3QAZA 1D9CA 1CN4C 3WCYI 1P9MB 2Y5YA 5FHXA 1EVSA 1BGEA 5A2NA 1M49A 1BP3A 1CYLA 2O26A 1M47A 1LKIA 4LDSA 3WDOA 3EW3A 1Y6KL 3H3VE 1RHGA 3HOZD 4A3GD 3UX9A 4NEMA 4GBYA 4A3JD 2B5IA 4YQXA 1HZIA 2LAGA 3BPLA 5C4XD 3EJJA 2VUMD 2LMSA 2H24A 3MZGA 4APSA 4OAAA 1HULA 4U4WA 3OG4A 1ITIA 1PV7A 4LRLA 4YBQA 4JR9A 3NCCA 3HOWD 1Y6NL 1EKUA 3UF2A 4IKVA 3NCEA 4Q65A 1A22A 1HIJA 3N0PA 4JREA 4IKWA 1Y14A 5C7XA 5D6KA 5C44D 2B8XA 1Y1VD 3FKID 1ILKA 5A2OA 4FA8E 5L6YC 1GA3A 1IL6A 4DKEA 4TPGA 2Z3RA 4ZWBA 1BUYA 4A3LD 3INKC 4YUEC 4GC0A 2D9QA 3HOUD 3UEZE 3D87A 5FLMD 3D48P 1SCFA 1WU3I 4A3DD 2JA7D 1AXIA 1A7MA 3BPNA 4IU9A 4DKDA 4NN7A 4PYPA 5IYCD 4CNIC 4ZF7A 1CNT1 5D70A 1BBNA 5KNHI 3L5XA 2JA8D 4EXNA 2Q98A 3B5KA 4D2CA 1F45B 4A3ED 3HOVD 3VA2A 1Z7CA 4W6VA 4UVMA 4TPJA 3PO3D 1VLKA 3DLQI 1RFBA 1M4BA 4JA3A 1PY2A 3O7QA 1HWGA 1PW4A 4BBSD 1RCBA 1B5LA 3LB6A 1IARA 4IU8A 4WRLB 2CFQA 4J05A 2C35A 4EXPA 1M4RA 4ZS7A 3SE3B 3DI3A 4O9HA 4XNIA 4D2DA 5D22A 4U4TA 1PVHB 4ZW9A 4X51A 4BY7D 5D59A 3PO2D 1HIKA 1JLIA 4BXXD 3HMXB 3L5WI 4GS7A 4ZWCA 2B8ZA 2Z3QA 3HHRA 3NCBA 3NPZA 4YB9D 4BBRD 4U4VA 2B8YA 2B90A 1AX8A 3N06A 2Q14A 2ILKA 2XQBA 4XNJA 4I77Z 3UF5A 3AYHA 3NCFA 1EERA 3I4MD 4YPGC 5FUCA 3SE4B 4NI9A 4Z5RD 1INRA 1BGDA 2GMFA 4A3KD 4LEPA 1ITLA 5GXBA 1HUWA 2ERJD 1M4CA 2JA5D 2OQPA 4GRWA 2R93D 4TPHA 2O6IA 5EQHA 1M48A
chains in the Genus database with same CATH topology
4IKZA 4JR9A 5A2OA 5EQIA 4YB9D 4IKXA 4XNIA 4IKVA 4D2CA 4Q65A 4D2DA 3O7PA 4IU8A 4U4VA 4U4TA 1PV6A 4TPGA 4LEPA 2Y5YA 4IU9A 2CFQA 4GBZA 4J05A 4W6VA 4UVMA 4JREA 4TPJA 4ZW9A 5A2NA 4IKYA 4ZYRA 4PYPA 5GXBA 4ZWBA 2CFPA 4APSA 4IKWA 5D59A 4GC0A 4OAAA 4U4WA 4LDSA 4OH3A 4QIQA 5D58A 4XNJA 3WDOA 4D2BA 4TPHA 2XUTA 4JA3A 1PV7A 2V8NA 5D6KA 5EQGA 5C65A 3O7QA 4YBQA 1PW4A 4ZWCA 4GBYA 5EQHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKZ A;  4JR9 A;  5A2O A;  5EQI A;  4YB9 D;  4IKX A;  4XNI A;  4IKV A;  4D2C A;  4Q65 A;  4D2D A;  3O7P A;  4IU8 A;  4U4V A;  4U4T A;  1PV6 A;  4TPG A;  4LEP A;  2Y5Y A;  4IU9 A;  2CFQ A;  4GBZ A;  4J05 A;  4W6V A;  4UVM A;  4JRE A;  4TPJ A;  4ZW9 A;  5A2N A;  4IKY A;  4ZYR A;  4PYP A;  5GXB A;  4ZWB A;  2CFP A;  4APS A;  4IKW A;  5D59 A;  4GC0 A;  4OAA A;  4U4W A;  4LDS A;  4OH3 A;  4QIQ A;  5D58 A;  4XNJ A;  3WDO A;  4D2B A;  4TPH A;  2XUT A;  4JA3 A;  1PV7 A;  2V8N A;  5D6K A;  5EQG A;  5C65 A;  3O7Q A;  4YBQ A;  1PW4 A;  4ZWC A;  4GBY A;  5EQH A; 
#chains in the Genus database with same CATH topology
 2KZ1 A;  2D48 A;  5EQI A;  4IKX A;  2JA6 D;  1KF9 A;  4RS1 A;  2L3O A;  1F6F A;  4A3M D;  1LK3 A;  2B91 A;  3H0G D;  2PSM A;  4IKY A;  2CFP A;  1BCN A;  1ITF A;  1QVN A;  1BGC A;  1M4A A;  4DKF A;  3PIV A;  5C65 A;  4BY1 D;  3Q1S I;  5LQB A;  5E4E A;  1D9G A;  4DOH A;  1EXZ A;  3HOY D;  1CSG A;  1HGU A;  2IL6 A;  1IRL A;  4YDY I;  3HHC A;  3G6D A;  3PIW A;  4NEJ A;  2O27 A;  3S9D A;  1PGR A;  4GBZ A;  3HOX D;  1HWH A;  1GNC A;  1FG9 A;  3QB1 A;  1ETE A;  4O6K A;  2CYK A;  4A3C D;  3OQ3 A;  4NN6 A;  4NKQ C;  4PS4 A;  1IK0 A;  2B8U A;  2L3Y A;  1Y1W D;  4A3I D;  5C3E D;  1LQS L;  1FYH A;  2HYM B;  1V7N V;  4OH3 A;  4D2B A;  5EQG A;  5D72 A;  1YKB A;  3TGX B;  2R7Z D;  4MHL A;  1ALU A;  3BPO A;  1PV6 A;  1PW6 A;  2R92 D;  3D85 C;  2INT A;  1IJZ A;  3BES L;  1J7V L;  2XUT A;  1RW5 A;  1V7M V;  4NI7 A;  5D28 B;  3DUH C;  1CD9 A;  3IRH A;  1Y6M L;  3O7P A;  1I1R B;  5IYB D;  1N1F A;  3LB6 B;  4NN5 A;  5D58 A;  4A3F D;  3QT2 C;  5TS9 A;  2B63 D;  3QWR B;  5D71 A;  1EMR A;  4A93 D;  3OG6 A;  1Z92 A;  4IKZ A;  5IYD D;  3QB7 A;  5IP7 D;  4J4L C;  2Q7N B;  4ZYR A;  4DKC A;  3DI2 A;  1ITM A;  1WCM D;  5IP9 D;  2E9W C;  4QIQ A;  3G9V B;  2V8N A;  3I4N D;  1AU1 A;  1NBP A;  4A3B D;  3DGC L;  3QAZ A;  1D9C A;  1CN4 C;  3WCY I;  1P9M B;  2Y5Y A;  5FHX A;  1EVS A;  1BGE A;  5A2N A;  1M49 A;  1BP3 A;  1CYL A;  2O26 A;  1M47 A;  1LKI A;  4LDS A;  3WDO A;  3EW3 A;  1Y6K L;  3H3V E;  1RHG A;  3HOZ D;  4A3G D;  3UX9 A;  4NEM A;  4GBY A;  4A3J D;  2B5I A;  4YQX A;  1HZI A;  2LAG A;  3BPL A;  5C4X D;  3EJJ A;  2VUM D;  2LMS A;  2H24 A;  3MZG A;  4APS A;  4OAA A;  1HUL A;  4U4W A;  3OG4 A;  1ITI A;  1PV7 A;  4LRL A;  4YBQ A;  4JR9 A;  3NCC A;  3HOW D;  1Y6N L;  1EKU A;  3UF2 A;  4IKV A;  3NCE A;  4Q65 A;  1A22 A;  1HIJ A;  3N0P A;  4JRE A;  4IKW A;  1Y14 A;  5C7X A;  5D6K A;  5C44 D;  2B8X A;  1Y1V D;  3FKI D;  1ILK A;  5A2O A;  4FA8 E;  5L6Y C;  1GA3 A;  1IL6 A;  4DKE A;  4TPG A;  2Z3R A;  4ZWB A;  1BUY A;  4A3L D;  3INK C;  4YUE C;  4GC0 A;  2D9Q A;  3HOU D;  3UEZ E;  3D87 A;  5FLM D;  3D48 P;  1SCF A;  1WU3 I;  4A3D D;  2JA7 D;  1AXI A;  1A7M A;  3BPN A;  4IU9 A;  4DKD A;  4NN7 A;  4PYP A;  5IYC D;  4CNI C;  4ZF7 A;  1CNT 1;  5D70 A;  1BBN A;  5KNH I;  3L5X A;  2JA8 D;  4EXN A;  2Q98 A;  3B5K A;  4D2C A;  1F45 B;  4A3E D;  3HOV D;  3VA2 A;  1Z7C A;  4W6V A;  4UVM A;  4TPJ A;  3PO3 D;  1VLK A;  3DLQ I;  1RFB A;  1M4B A;  4JA3 A;  1PY2 A;  3O7Q A;  1HWG A;  1PW4 A;  4BBS D;  1RCB A;  1B5L A;  3LB6 A;  1IAR A;  4IU8 A;  4WRL B;  2CFQ A;  4J05 A;  2C35 A;  4EXP A;  1M4R A;  4ZS7 A;  3SE3 B;  3DI3 A;  4O9H A;  4XNI A;  4D2D A;  5D22 A;  4U4T A;  1PVH B;  4ZW9 A;  4X51 A;  4BY7 D;  5D59 A;  3PO2 D;  1HIK A;  1JLI A;  4BXX D;  3HMX B;  3L5W I;  4GS7 A;  4ZWC A;  2B8Z A;  2Z3Q A;  3HHR A;  3NCB A;  3NPZ A;  4YB9 D;  4BBR D;  4U4V A;  2B8Y A;  2B90 A;  1AX8 A;  3N06 A;  2Q14 A;  2ILK A;  2XQB A;  4XNJ A;  4I77 Z;  3UF5 A;  3AYH A;  3NCF A;  1EER A;  3I4M D;  4YPG C;  5FUC A;  3SE4 B;  4NI9 A;  4Z5R D;  1INR A;  1BGD A;  2GMF A;  4A3K D;  4LEP A;  1ITL A;  5GXB A;  1HUW A;  2ERJ D;  1M4C A;  2JA5 D;  2OQP A;  4GRW A;  2R93 D;  4TPH A;  2O6I A;  5EQH A;  1M48 A; 
#chains in the Genus database with same CATH homology
 4IKZ A;  4JR9 A;  5A2O A;  5EQI A;  4YB9 D;  4IKX A;  4XNI A;  4IKV A;  4D2C A;  4Q65 A;  4D2D A;  3O7P A;  4IU8 A;  4U4V A;  4U4T A;  1PV6 A;  4TPG A;  4LEP A;  2Y5Y A;  4IU9 A;  2CFQ A;  4GBZ A;  4J05 A;  4W6V A;  4UVM A;  4JRE A;  4TPJ A;  4ZW9 A;  5A2N A;  4IKY A;  4ZYR A;  4PYP A;  5GXB A;  4ZWB A;  2CFP A;  4APS A;  4IKW A;  5D59 A;  4GC0 A;  4OAA A;  4U4W A;  4LDS A;  4OH3 A;  4QIQ A;  5D58 A;  4XNJ A;  3WDO A;  4D2B A;  4TPH A;  2XUT A;  4JA3 A;  1PV7 A;  2V8N A;  5D6K A;  5EQG A;  5C65 A;  3O7Q A;  4YBQ A;  1PW4 A;  4ZWC A;  4GBY A;  5EQH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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