1WCMD

Complete 12-subunit rna polymerase ii at 3.8 angstrom
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
177
structure length
177
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Complete RNA Polymerase II and its Subcomplex,Rpb4/7
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 42
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2004-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 1wcmD02
3H3VE 4A3JD 4A3LD 2R7ZD 1Y14A 4A3MD 5C3ED 2B63D 3PO3D 2R93D 2C35A 5C4XD 5C44D 3H0GD 5IP9D 4A3ED 3HOYD 4A3GD 2R92D 2JA8D 5IYDD 5IYCD 3FKID 5IP7D 5FLMD 2JA6D 1Y1WD 3PO2D 4A3BD 4A93D 3HOZD 4BBSD 4BY7D 3HOXD 5IYBD 4A3CD 4A3ID 1Y1VD 4A3DD 2VUMD 4BY1D 2JA7D 4BBRD 4A3KD 3HOWD 4BXXD 3HOVD 3I4MD 3I4ND 4A3FD 2JA5D 3HOUD 3AYHA 1WCMD
chains in the Genus database with same CATH superfamily
4J4LC 4J05A 4A3LD 3O7QA 1M4CA 1IJZA 4Z5RD 4PYPA 5IP9D 2Y5YA 2JA6D 4BY7D 1INRA 2E9WC 3PIVA 5D72A 5D58A 4D2BA 1M49A 4A3CD 3BPOA 3DLQI 1M47A 3I4ND 3EJJA 4A3MD 2C35A 2IL6A 3WCYI 3NCCA 4IU9A 5EQIA 2V8NA 2VUMD 3SE3B 2CFQA 1CN4C 3I4MD 2PSMA 1V7MV 4ZS7A 4DKFA 2CFPA 5C44D 4A3GD 1BGDA 5D6KA 1M4AA 5TS9A 2D48A 5D28B 2LAGA 1IARA 4ZF7A 4PS4A 3UX9A 3HOWD 1BGCA 3H3VE 4FA8E 2R7ZD 4OAAA 5D70A 2JA8D 3SE4B 4NN5A 1HULA 3MZGA 4JA3A 4LDSA 1ITIA 1ITLA 4NN7A 5A2OA 4UVMA 3NCBA 4YQXA 2B8YA 1RHGA 5GXBA 3TGXB 1AX8A 3PO3D 2KZ1A 4A3ED 2Q7NB 4CNIC 3FKID 3O7PA 5IYBD 4U4WA 1RFBA 4DOHA 4XNIA 5D59A 4D2DA 2B8UA 4GBZA 1B5LA 4QIQA 3HMXB 1PY2A 1NBPA 4XNJA 1EERA 2B8ZA 1HUWA 4NEJA 1Y6NL 4A3DD 4GC0A 3LB6B 2B63D 5C7XA 4IKXA 4GBYA 1BCNA 1LK3A 5FLMD 1BBNA 1N1FA 3OQ3A 2B91A 3S9DA 2B90A 1ITMA 1M4RA 1EKUA 1VLKA 1HWGA 3NCFA 2O26A 3DI3A 1WU3I 1HWHA 4DKCA 4IKYA 1ILKA 3N06A 1D9GA 3EW3A 3QT2C 5L6YC 2B8XA 1ALUA 3HHRA 1BUYA 3UF2A 3D48P 2Z3QA 4U4VA 2Q98A 1A7MA 2Z3RA 5A2NA 3AYHA 1JLIA 3G6DA 1Y14A 1PVHB 2R93D 1PV6A 3HOYD 1LQSL 1RW5A 1PGRA 3NPZA 2XQBA 3HHCA 3QWRB 4OH3A 5FHXA 2HYMB 2LMSA 1SCFA 3OG6A 1IRLA 2L3YA 3QAZA 4IKVA 3INKC 1BGEA 3UF5A 2H24A 5E4EA 4X51A 5IYDD 3PO2D 3OG4A 4NKQC 2L3OA 1M4BA 1Y6KL 1CD9A 1V7NV 4YUEC 1PV7A 1WCMD 5EQGA 5LQBA 1CSGA 4A3BD 1RCBA 4A93D 4I77Z 1Y6ML 1HIKA 4LRLA 2XUTA 5D71A 1M48A 1Z92A 1GNCA 1YKBA 2JA7D 1EXZA 4NI9A 4ZW9A 2INTA 1EMRA 1P9MB 4IU8A 4ZYRA 1IK0A 4APSA 3N0PA 2O27A 3VA2A 4O9HA 5C4XD 1F6FA 4D2CA 1CYLA 2R92D 4YBQA 4IKWA 5IP7D 4U4TA 1AXIA 1KF9A 4RS1A 4NI7A 4BY1D 4JR9A 3BPNA 4YB9D 4TPHA 4MHLA 2Q14A 4YDYI 1PW6A 4ZWCA 2D9QA 4YPGC 4GS7A 4A3ID 3BESL 1I1RB 4BBRD 4LEPA 1F45B 3LB6A 2B5IA 4WRLB 4IKZA 4A3JD 3B5KA 3L5WI 3Q1SI 3IRHA 1D9CA 1J7VL 3UEZE 1FG9A 1HGUA 3D87A 3L5XA 3PIWA 4Q65A 4NN6A 4A3KD 3QB7A 2ILKA 3QB1A 4A3FD 1IL6A 2JA5D 3DI2A 3DUHC 1CNT1 1EVSA 4DKEA 1ITFA 1BP3A 2O6IA 1A22A 5FUCA 5IYCD 3HOZD 4BBSD 5C65A 1PW4A 3HOXD 4EXPA 4BXXD 1FYHA 2ERJD 4ZWBA 1GA3A 1AU1A 2CYKA 3D85C 4GRWA 5C3ED 1QVNA 5EQHA 1ETEA 3H0GD 3DGCL 4TPGA 4NEMA 1Y1WD 3WDOA 5D22A 4EXNA 1Z7CA 1HZIA 3NCEA 1LKIA 4W6VA 2GMFA 1Y1VD 4O6KA 1HIJA 2OQPA 3HOVD 3BPLA 3G9VB 4TPJA 5KNHI 4JREA 3HOUD 4DKDA
chains in the Genus database with same CATH topology
1AX8A 4J4LC 1JLIA 4A3LD 4MHLA 3G6DA 1Y14A 1M4CA 1PVHB 2KZ1A 2Q14A 3PO3D 1IJZA 4Z5RD 2R93D 4YDYI 5IP9D 4A3ED 1LQSL 3HOYD 2Q7NB 1PW6A 4CNIC 2JA6D 3FKID 4BY7D 1INRA 2E9WC 3HOZD 3PIVA 5D72A 5IYBD 2D9QA 1RW5A 4YPGC 1M49A 4GS7A 4A3CD 1PGRA 4A3ID 3NPZA 2XQBA 1RFBA 3HHCA 3BESL 3QWRB 5FHXA 1I1RB 3BPOA 4BBRD 4DOHA 2HYMB 2LMSA 3DLQI 1M47A 1SCFA 3I4ND 2B8UA 3OG6A 1B5LA 1F45B 1IRLA 2L3YA 3EJJA 3QAZA 3LB6A 2B5IA 4WRLB 3INKC 4A3JD 3HMXB 3B5KA 1BGEA 4A3MD 3L5WI 3Q1SI 3UF5A 1PY2A 2C35A 2H24A 2IL6A 3WCYI 3NCCA 3IRHA 4X51A 1D9CA 5E4EA 5IYDD 1J7VL 3UEZE 3OG4A 1FG9A 1HGUA 3PO2D 1NBPA 3D87A 4NKQC 2L3OA 1M4BA 1EERA 3L5XA 2B8ZA 1Y6KL 1HUWA 3PIWA 1CD9A 4NEJA 1Y6NL 4A3DD 2VUMD 1V7NV 4NN6A 3SE3B 4A3KD 3QB7A 1CN4C 4YUEC 2ILKA 3I4MD 3QB1A 2PSMA 1V7MV 4A3FD 1IL6A 4ZS7A 2JA5D 1WCMD 3DI2A 3DUHC 4DKFA 1CNT1 1EVSA 3LB6B 5LQBA 4DKEA 1ITFA 1BP3A 2O6IA 2B63D 1A22A 5FUCA 5C44D 5C7XA 4A3GD 1BCNA 1BGDA 1CSGA 1LK3A 5IYCD 5FLMD 1RCBA 4A3BD 4A93D 4I77Z 1Y6ML 1BBNA 1HIKA 4LRLA 1M4AA 1N1FA 2D48A 5TS9A 5D71A 3OQ3A 2B91A 3S9DA 5D28B 2B90A 2LAGA 3HOXD 1IARA 1M48A 1ITMA 1M4RA 4ZF7A 4PS4A 1EKUA 1Z92A 1GNCA 1YKBA 2JA7D 3UX9A 4EXPA 1VLKA 1EXZA 3HOWD 4NI9A 4BXXD 1HWGA 3NCFA 2INTA 1EMRA 1FYHA 2ERJD 1WU3I 1HWHA 2O26A 1P9MB 1BGCA 3DI3A 4DKCA 1GA3A 1IK0A 1AU1A 4BBSD 1ILKA 3N06A 2CYKA 3N0PA 3TGXB 3H3VE 1D9GA 3D85C 3EW3A 4FA8E 2R7ZD 3QT2C 4GRWA 2O27A 3VA2A 1QVNA 2B8XA 4O9HA 5L6YC 5C3ED 1ETEA 1F6FA 5C4XD 5D70A 3H0GD 1ALUA 3DGCL 1CYLA 2R92D 2JA8D 3SE4B 4NN5A 5IP7D 3HHRA 1HULA 4NEMA 3MZGA 1Y1WD 1BUYA 1AXIA 3UF2A 1KF9A 5D22A 4EXNA 1Z7CA 1HZIA 3D48P 3NCEA 4RS1A 4NI7A 1ITIA 1ITLA 1LKIA 2Z3QA 4NN7A 2GMFA 1Y1VD 4O6KA 4BY1D 1HIJA 2OQPA 3HOVD 3BPLA 3G9VB 2Q98A 3NCBA 4YQXA 2Z3RA 1A7MA 5KNHI 2B8YA 1RHGA 3BPNA 3HOUD 3AYHA 4DKDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H3V E;  4A3J D;  4A3L D;  2R7Z D;  1Y14 A;  4A3M D;  5C3E D;  2B63 D;  3PO3 D;  2R93 D;  2C35 A;  5C4X D;  5C44 D;  3H0G D;  5IP9 D;  4A3E D;  3HOY D;  4A3G D;  2R92 D;  2JA8 D;  5IYD D;  5IYC D;  3FKI D;  5IP7 D;  5FLM D;  2JA6 D;  1Y1W D;  3PO2 D;  4A3B D;  4A93 D;  3HOZ D;  4BBS D;  4BY7 D;  3HOX D;  5IYB D;  4A3C D;  4A3I D;  1Y1V D;  4A3D D;  2VUM D;  4BY1 D;  2JA7 D;  4BBR D;  4A3K D;  3HOW D;  4BXX D;  3HOV D;  3I4M D;  3I4N D;  4A3F D;  2JA5 D;  3HOU D;  3AYH A;  1WCM D; 
#chains in the Genus database with same CATH topology
 4J4L C;  4J05 A;  4A3L D;  3O7Q A;  1M4C A;  1IJZ A;  4Z5R D;  4PYP A;  5IP9 D;  2Y5Y A;  2JA6 D;  4BY7 D;  1INR A;  2E9W C;  3PIV A;  5D72 A;  5D58 A;  4D2B A;  1M49 A;  4A3C D;  3BPO A;  3DLQ I;  1M47 A;  3I4N D;  3EJJ A;  4A3M D;  2C35 A;  2IL6 A;  3WCY I;  3NCC A;  4IU9 A;  5EQI A;  2V8N A;  2VUM D;  3SE3 B;  2CFQ A;  1CN4 C;  3I4M D;  2PSM A;  1V7M V;  4ZS7 A;  4DKF A;  2CFP A;  5C44 D;  4A3G D;  1BGD A;  5D6K A;  1M4A A;  5TS9 A;  2D48 A;  5D28 B;  2LAG A;  1IAR A;  4ZF7 A;  4PS4 A;  3UX9 A;  3HOW D;  1BGC A;  3H3V E;  4FA8 E;  2R7Z D;  4OAA A;  5D70 A;  2JA8 D;  3SE4 B;  4NN5 A;  1HUL A;  3MZG A;  4JA3 A;  4LDS A;  1ITI A;  1ITL A;  4NN7 A;  5A2O A;  4UVM A;  3NCB A;  4YQX A;  2B8Y A;  1RHG A;  5GXB A;  3TGX B;  1AX8 A;  3PO3 D;  2KZ1 A;  4A3E D;  2Q7N B;  4CNI C;  3FKI D;  3O7P A;  5IYB D;  4U4W A;  1RFB A;  4DOH A;  4XNI A;  5D59 A;  4D2D A;  2B8U A;  4GBZ A;  1B5L A;  4QIQ A;  3HMX B;  1PY2 A;  1NBP A;  4XNJ A;  1EER A;  2B8Z A;  1HUW A;  4NEJ A;  1Y6N L;  4A3D D;  4GC0 A;  3LB6 B;  2B63 D;  5C7X A;  4IKX A;  4GBY A;  1BCN A;  1LK3 A;  5FLM D;  1BBN A;  1N1F A;  3OQ3 A;  2B91 A;  3S9D A;  2B90 A;  1ITM A;  1M4R A;  1EKU A;  1VLK A;  1HWG A;  3NCF A;  2O26 A;  3DI3 A;  1WU3 I;  1HWH A;  4DKC A;  4IKY A;  1ILK A;  3N06 A;  1D9G A;  3EW3 A;  3QT2 C;  5L6Y C;  2B8X A;  1ALU A;  3HHR A;  1BUY A;  3UF2 A;  3D48 P;  2Z3Q A;  4U4V A;  2Q98 A;  1A7M A;  2Z3R A;  5A2N A;  3AYH A;  1JLI A;  3G6D A;  1Y14 A;  1PVH B;  2R93 D;  1PV6 A;  3HOY D;  1LQS L;  1RW5 A;  1PGR A;  3NPZ A;  2XQB A;  3HHC A;  3QWR B;  4OH3 A;  5FHX A;  2HYM B;  2LMS A;  1SCF A;  3OG6 A;  1IRL A;  2L3Y A;  3QAZ A;  4IKV A;  3INK C;  1BGE A;  3UF5 A;  2H24 A;  5E4E A;  4X51 A;  5IYD D;  3PO2 D;  3OG4 A;  4NKQ C;  2L3O A;  1M4B A;  1Y6K L;  1CD9 A;  1V7N V;  4YUE C;  1PV7 A;  1WCM D;  5EQG A;  5LQB A;  1CSG A;  4A3B D;  1RCB A;  4A93 D;  4I77 Z;  1Y6M L;  1HIK A;  4LRL A;  2XUT A;  5D71 A;  1M48 A;  1Z92 A;  1GNC A;  1YKB A;  2JA7 D;  1EXZ A;  4NI9 A;  4ZW9 A;  2INT A;  1EMR A;  1P9M B;  4IU8 A;  4ZYR A;  1IK0 A;  4APS A;  3N0P A;  2O27 A;  3VA2 A;  4O9H A;  5C4X D;  1F6F A;  4D2C A;  1CYL A;  2R92 D;  4YBQ A;  4IKW A;  5IP7 D;  4U4T A;  1AXI A;  1KF9 A;  4RS1 A;  4NI7 A;  4BY1 D;  4JR9 A;  3BPN A;  4YB9 D;  4TPH A;  4MHL A;  2Q14 A;  4YDY I;  1PW6 A;  4ZWC A;  2D9Q A;  4YPG C;  4GS7 A;  4A3I D;  3BES L;  1I1R B;  4BBR D;  4LEP A;  1F45 B;  3LB6 A;  2B5I A;  4WRL B;  4IKZ A;  4A3J D;  3B5K A;  3L5W I;  3Q1S I;  3IRH A;  1D9C A;  1J7V L;  3UEZ E;  1FG9 A;  1HGU A;  3D87 A;  3L5X A;  3PIW A;  4Q65 A;  4NN6 A;  4A3K D;  3QB7 A;  2ILK A;  3QB1 A;  4A3F D;  1IL6 A;  2JA5 D;  3DI2 A;  3DUH C;  1CNT 1;  1EVS A;  4DKE A;  1ITF A;  1BP3 A;  2O6I A;  1A22 A;  5FUC A;  5IYC D;  3HOZ D;  4BBS D;  5C65 A;  1PW4 A;  3HOX D;  4EXP A;  4BXX D;  1FYH A;  2ERJ D;  4ZWB A;  1GA3 A;  1AU1 A;  2CYK A;  3D85 C;  4GRW A;  5C3E D;  1QVN A;  5EQH A;  1ETE A;  3H0G D;  3DGC L;  4TPG A;  4NEM A;  1Y1W D;  3WDO A;  5D22 A;  4EXN A;  1Z7C A;  1HZI A;  3NCE A;  1LKI A;  4W6V A;  2GMF A;  1Y1V D;  4O6K A;  1HIJ A;  2OQP A;  3HOV D;  3BPL A;  3G9V B;  4TPJ A;  5KNH I;  4JRE A;  3HOU D;  4DKD A; 
#chains in the Genus database with same CATH homology
 1AX8 A;  4J4L C;  1JLI A;  4A3L D;  4MHL A;  3G6D A;  1Y14 A;  1M4C A;  1PVH B;  2KZ1 A;  2Q14 A;  3PO3 D;  1IJZ A;  4Z5R D;  2R93 D;  4YDY I;  5IP9 D;  4A3E D;  1LQS L;  3HOY D;  2Q7N B;  1PW6 A;  4CNI C;  2JA6 D;  3FKI D;  4BY7 D;  1INR A;  2E9W C;  3HOZ D;  3PIV A;  5D72 A;  5IYB D;  2D9Q A;  1RW5 A;  4YPG C;  1M49 A;  4GS7 A;  4A3C D;  1PGR A;  4A3I D;  3NPZ A;  2XQB A;  1RFB A;  3HHC A;  3BES L;  3QWR B;  5FHX A;  1I1R B;  3BPO A;  4BBR D;  4DOH A;  2HYM B;  2LMS A;  3DLQ I;  1M47 A;  1SCF A;  3I4N D;  2B8U A;  3OG6 A;  1B5L A;  1F45 B;  1IRL A;  2L3Y A;  3EJJ A;  3QAZ A;  3LB6 A;  2B5I A;  4WRL B;  3INK C;  4A3J D;  3HMX B;  3B5K A;  1BGE A;  4A3M D;  3L5W I;  3Q1S I;  3UF5 A;  1PY2 A;  2C35 A;  2H24 A;  2IL6 A;  3WCY I;  3NCC A;  3IRH A;  4X51 A;  1D9C A;  5E4E A;  5IYD D;  1J7V L;  3UEZ E;  3OG4 A;  1FG9 A;  1HGU A;  3PO2 D;  1NBP A;  3D87 A;  4NKQ C;  2L3O A;  1M4B A;  1EER A;  3L5X A;  2B8Z A;  1Y6K L;  1HUW A;  3PIW A;  1CD9 A;  4NEJ A;  1Y6N L;  4A3D D;  2VUM D;  1V7N V;  4NN6 A;  3SE3 B;  4A3K D;  3QB7 A;  1CN4 C;  4YUE C;  2ILK A;  3I4M D;  3QB1 A;  2PSM A;  1V7M V;  4A3F D;  1IL6 A;  4ZS7 A;  2JA5 D;  1WCM D;  3DI2 A;  3DUH C;  4DKF A;  1CNT 1;  1EVS A;  3LB6 B;  5LQB A;  4DKE A;  1ITF A;  1BP3 A;  2O6I A;  2B63 D;  1A22 A;  5FUC A;  5C44 D;  5C7X A;  4A3G D;  1BCN A;  1BGD A;  1CSG A;  1LK3 A;  5IYC D;  5FLM D;  1RCB A;  4A3B D;  4A93 D;  4I77 Z;  1Y6M L;  1BBN A;  1HIK A;  4LRL A;  1M4A A;  1N1F A;  2D48 A;  5TS9 A;  5D71 A;  3OQ3 A;  2B91 A;  3S9D A;  5D28 B;  2B90 A;  2LAG A;  3HOX D;  1IAR A;  1M48 A;  1ITM A;  1M4R A;  4ZF7 A;  4PS4 A;  1EKU A;  1Z92 A;  1GNC A;  1YKB A;  2JA7 D;  3UX9 A;  4EXP A;  1VLK A;  1EXZ A;  3HOW D;  4NI9 A;  4BXX D;  1HWG A;  3NCF A;  2INT A;  1EMR A;  1FYH A;  2ERJ D;  1WU3 I;  1HWH A;  2O26 A;  1P9M B;  1BGC A;  3DI3 A;  4DKC A;  1GA3 A;  1IK0 A;  1AU1 A;  4BBS D;  1ILK A;  3N06 A;  2CYK A;  3N0P A;  3TGX B;  3H3V E;  1D9G A;  3D85 C;  3EW3 A;  4FA8 E;  2R7Z D;  3QT2 C;  4GRW A;  2O27 A;  3VA2 A;  1QVN A;  2B8X A;  4O9H A;  5L6Y C;  5C3E D;  1ETE A;  1F6F A;  5C4X D;  5D70 A;  3H0G D;  1ALU A;  3DGC L;  1CYL A;  2R92 D;  2JA8 D;  3SE4 B;  4NN5 A;  5IP7 D;  3HHR A;  1HUL A;  4NEM A;  3MZG A;  1Y1W D;  1BUY A;  1AXI A;  3UF2 A;  1KF9 A;  5D22 A;  4EXN A;  1Z7C A;  1HZI A;  3D48 P;  3NCE A;  4RS1 A;  4NI7 A;  1ITI A;  1ITL A;  1LKI A;  2Z3Q A;  4NN7 A;  2GMF A;  1Y1V D;  4O6K A;  4BY1 D;  1HIJ A;  2OQP A;  3HOV D;  3BPL A;  3G9V B;  2Q98 A;  3NCB A;  4YQX A;  2Z3R A;  1A7M A;  5KNH I;  2B8Y A;  1RHG A;  3BPN A;  3HOU D;  3AYH A;  4DKD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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