1PV6A

Crystal structure of lactose permease
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
417
structure length
417
Chain Sequence
MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALGASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of the lactose permease of Escherichia coli
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords Lactose permease
total genus 141
structure length 417
sequence length 417
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01306 LacY_symp LacY proton/sugar symporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 1pv6A02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 1pv6A01
4D2BA 1PW4A 4OAAA 4XNJA 4QIQA 4JREA 4IKYA 3O7PA 4ZW9A 4GC0A 5A2OA 4GBZA 4W6VA 2V8NA 4IKZA 4TPHA 4D2CA 4Q65A 2XUTA 4IU9A 4LEPA 5D58A 1PV7A 5EQGA 5EQHA 4ZWBA 4APSA 4OH3A 5A2NA 4TPJA 4IKVA 4LDSA 3WDOA 4IKXA 5EQIA 4IKWA 4XNIA 2Y5YA 4PYPA 4GBYA 2CFQA 4UVMA 5D59A 3O7QA 5D6KA 4D2DA 4U4VA 4YB9D 4J05A 4U4WA 4JR9A 1PV6A 4TPGA 4YBQA 4U4TA 4ZYRA 5GXBA 4IU8A 4JA3A 4ZWCA 5C65A 2CFPA
chains in the Genus database with same CATH superfamily
1Y1WD 4GS7A 4XNJA 4IKYA 2L3YA 4DKFA 2Q7NB 2O6IA 4W6VA 5IYCD 2B8UA 5EQHA 2B63D 3G9VB 5D71A 2Z3QA 4IKVA 4LDSA 3EW3A 1IJZA 2O26A 2L3OA 4NN5A 4U4VA 4Z5RD 4LRLA 2KZ1A 2O27A 1BGEA 1I1RB 1Z7CA 1VLKA 3EJJA 3L5XA 2V8NA 4IKZA 4TPHA 4RS1A 3WDOA 1RHGA 1WCMD 1V7MV 1B5LA 2INTA 2C35A 5E4EA 1RCBA 1AX8A 3G6DA 3UF5A 5A2OA 4GBZA 1HIJA 1ITIA 1BBNA 5EQIA 1M47A 5D6KA 5L6YC 4BY7D 2Z3RA 4MHLA 5LQBA 2VUMD 4JREA 2PSMA 3IRHA 1EXZA 2LAGA 3UF2A 1GA3A 4OH3A 1ALUA 4GBYA 5D22A 3HHCA 5IP7D 2D9QA 4TPGA 1BUYA 2B5IA 4A3JD 2B8YA 4A3LD 1WU3I 4OAAA 1EVSA 4QIQA 4J4LC 4A3FD 3BESL 3LB6A 4YUEC 2B90A 5D70A 1M49A 2Q98A 3DUHC 4A3ID 4ZYRA 4U4TA 4A3KD 5C65A 4ZF7A 4BXXD 3D87A 2JA7D 3I4MD 4DOHA 3N0PA 5D28B 4A3MD 2D48A 2CFQA 2B8XA 3O7QA 1D9GA 1V7NV 1HWHA 1M4CA 1PW6A 4A3CD 3N06A 3UEZE 4DKEA 4D2BA 4ZW9A 3HOYD 4WRLB 3PIWA 3HHRA 3INKC 4NI7A 1CNT1 2JA8D 5C7XA 1IARA 1PVHB 4NEMA 3AYHA 3HOWD 1HGUA 2OQPA 3QB7A 4D2DA 3NCEA 2CFPA 2B8ZA 3FKID 1CYLA 1M4RA 4A3GD 2JA6D 4D2CA 4Q65A 5EQGA 4ZWBA 4X51A 4EXPA 3DLQI 1Y6NL 1PGRA 2GMFA 3MZGA 1F45B 4J05A 1LKIA 1BP3A 5FLMD 4ZS7A 4ZWCA 1ETEA 3UX9A 1AU1A 3HOVD 2JA5D 3H0GD 2R93D 4IU9A 5C44D 3OG4A 2Y5YA 1RFBA 1CSGA 1CN4C 3I4ND 4I77Z 1JLIA 4JR9A 3VA2A 3L5WI 1F6FA 2E9WC 5IP9D 4A93D 3DGCL 4DKDA 3QAZA 1Y14A 5A2NA 1LK3A 1PY2A 2HYMB 1J7VL 5D59A 4CNIC 2ERJD 3TGXB 2XQBA 3QWRB 4A3DD 4U4WA 1HULA 5GXBA 1D9CA 1A22A 5C3ED 3BPNA 3HMXB 3NCBA 4PS4A 1HIKA 2R7ZD 1LQSL 3PIVA 1ILKA 4NN7A 4APSA 3SE4B 3BPLA 4IKXA 3OQ3A 4IKWA 4XNIA 3HOXD 4UVMA 4NEJA 4JA3A 2IL6A 2H24A 4O9HA 4YDYI 1HWGA 5FHXA 4EXNA 3DI2A 5IYDD 2ILKA 1Y6KL 2XUTA 3H3VE 1ITLA 1PV7A 1M4BA 1IRLA 1SCFA 1QVNA 4YPGC 1Z92A 3HOZD 1HUWA 1BGCA 1RW5A 4GRWA 3WCYI 1YKBA 1ITFA 1HZIA 4NKQC 5C4XD 4BBRD 3O7PA 5IYBD 3NCFA 4TPJA 3QB1A 4PYPA 3HOUD 2B91A 3S9DA 4FA8E 4A3ED 3NCCA 1GNCA 3D85C 1N1FA 4YQXA 1AXIA 1Y1VD 1IL6A 1M48A 1A7MA 4O6KA 1EKUA 1FG9A 4LEPA 1P9MB 1KF9A 4BY1D 3BPOA 1ITMA 3NPZA 5D72A 1FYHA 5KNHI 3D48P 4YBQA 1BCNA 4IU8A 1EMRA 1INRA 4DKCA 4NI9A 1EERA 4GC0A 2Q14A 1M4AA 5D58A 4NN6A 1CD9A 1Y6ML 3DI3A 4YB9D 1PV6A 3Q1SI 1IK0A 3LB6B 1PW4A 5FUCA 1BGDA 1NBPA 3PO3D 3QT2C 4BBSD 2LMSA 2R92D 4A3BD 2CYKA 5TS9A 3B5KA 3PO2D 3SE3B 3OG6A
chains in the Genus database with same CATH topology
4D2BA 1PW4A 4OAAA 4XNJA 4QIQA 4JREA 4IKYA 3O7PA 4ZW9A 4GC0A 5A2OA 4GBZA 4W6VA 2V8NA 4IKZA 4TPHA 4D2CA 4Q65A 2XUTA 4IU9A 4LEPA 5D58A 1PV7A 5EQGA 5EQHA 4ZWBA 4APSA 4OH3A 5A2NA 4TPJA 4IKVA 4LDSA 3WDOA 4IKXA 5EQIA 4IKWA 4XNIA 2Y5YA 4PYPA 4GBYA 2CFQA 4UVMA 5D59A 3O7QA 5D6KA 4D2DA 4U4VA 4YB9D 4J05A 4U4WA 4JR9A 1PV6A 4TPGA 4YBQA 4U4TA 4ZYRA 5GXBA 4IU8A 4JA3A 4ZWCA 5C65A 2CFPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D2B A;  1PW4 A;  4OAA A;  4XNJ A;  4QIQ A;  4JRE A;  4IKY A;  3O7P A;  4ZW9 A;  4GC0 A;  5A2O A;  4GBZ A;  4W6V A;  2V8N A;  4IKZ A;  4TPH A;  4D2C A;  4Q65 A;  2XUT A;  4IU9 A;  4LEP A;  5D58 A;  1PV7 A;  5EQG A;  5EQH A;  4ZWB A;  4APS A;  4OH3 A;  5A2N A;  4TPJ A;  4IKV A;  4LDS A;  3WDO A;  4IKX A;  5EQI A;  4IKW A;  4XNI A;  2Y5Y A;  4PYP A;  4GBY A;  2CFQ A;  4UVM A;  5D59 A;  3O7Q A;  5D6K A;  4D2D A;  4U4V A;  4YB9 D;  4J05 A;  4U4W A;  4JR9 A;  1PV6 A;  4TPG A;  4YBQ A;  4U4T A;  4ZYR A;  5GXB A;  4IU8 A;  4JA3 A;  4ZWC A;  5C65 A;  2CFP A; 
#chains in the Genus database with same CATH topology
 1Y1W D;  4GS7 A;  4XNJ A;  4IKY A;  2L3Y A;  4DKF A;  2Q7N B;  2O6I A;  4W6V A;  5IYC D;  2B8U A;  5EQH A;  2B63 D;  3G9V B;  5D71 A;  2Z3Q A;  4IKV A;  4LDS A;  3EW3 A;  1IJZ A;  2O26 A;  2L3O A;  4NN5 A;  4U4V A;  4Z5R D;  4LRL A;  2KZ1 A;  2O27 A;  1BGE A;  1I1R B;  1Z7C A;  1VLK A;  3EJJ A;  3L5X A;  2V8N A;  4IKZ A;  4TPH A;  4RS1 A;  3WDO A;  1RHG A;  1WCM D;  1V7M V;  1B5L A;  2INT A;  2C35 A;  5E4E A;  1RCB A;  1AX8 A;  3G6D A;  3UF5 A;  5A2O A;  4GBZ A;  1HIJ A;  1ITI A;  1BBN A;  5EQI A;  1M47 A;  5D6K A;  5L6Y C;  4BY7 D;  2Z3R A;  4MHL A;  5LQB A;  2VUM D;  4JRE A;  2PSM A;  3IRH A;  1EXZ A;  2LAG A;  3UF2 A;  1GA3 A;  4OH3 A;  1ALU A;  4GBY A;  5D22 A;  3HHC A;  5IP7 D;  2D9Q A;  4TPG A;  1BUY A;  2B5I A;  4A3J D;  2B8Y A;  4A3L D;  1WU3 I;  4OAA A;  1EVS A;  4QIQ A;  4J4L C;  4A3F D;  3BES L;  3LB6 A;  4YUE C;  2B90 A;  5D70 A;  1M49 A;  2Q98 A;  3DUH C;  4A3I D;  4ZYR A;  4U4T A;  4A3K D;  5C65 A;  4ZF7 A;  4BXX D;  3D87 A;  2JA7 D;  3I4M D;  4DOH A;  3N0P A;  5D28 B;  4A3M D;  2D48 A;  2CFQ A;  2B8X A;  3O7Q A;  1D9G A;  1V7N V;  1HWH A;  1M4C A;  1PW6 A;  4A3C D;  3N06 A;  3UEZ E;  4DKE A;  4D2B A;  4ZW9 A;  3HOY D;  4WRL B;  3PIW A;  3HHR A;  3INK C;  4NI7 A;  1CNT 1;  2JA8 D;  5C7X A;  1IAR A;  1PVH B;  4NEM A;  3AYH A;  3HOW D;  1HGU A;  2OQP A;  3QB7 A;  4D2D A;  3NCE A;  2CFP A;  2B8Z A;  3FKI D;  1CYL A;  1M4R A;  4A3G D;  2JA6 D;  4D2C A;  4Q65 A;  5EQG A;  4ZWB A;  4X51 A;  4EXP A;  3DLQ I;  1Y6N L;  1PGR A;  2GMF A;  3MZG A;  1F45 B;  4J05 A;  1LKI A;  1BP3 A;  5FLM D;  4ZS7 A;  4ZWC A;  1ETE A;  3UX9 A;  1AU1 A;  3HOV D;  2JA5 D;  3H0G D;  2R93 D;  4IU9 A;  5C44 D;  3OG4 A;  2Y5Y A;  1RFB A;  1CSG A;  1CN4 C;  3I4N D;  4I77 Z;  1JLI A;  4JR9 A;  3VA2 A;  3L5W I;  1F6F A;  2E9W C;  5IP9 D;  4A93 D;  3DGC L;  4DKD A;  3QAZ A;  1Y14 A;  5A2N A;  1LK3 A;  1PY2 A;  2HYM B;  1J7V L;  5D59 A;  4CNI C;  2ERJ D;  3TGX B;  2XQB A;  3QWR B;  4A3D D;  4U4W A;  1HUL A;  5GXB A;  1D9C A;  1A22 A;  5C3E D;  3BPN A;  3HMX B;  3NCB A;  4PS4 A;  1HIK A;  2R7Z D;  1LQS L;  3PIV A;  1ILK A;  4NN7 A;  4APS A;  3SE4 B;  3BPL A;  4IKX A;  3OQ3 A;  4IKW A;  4XNI A;  3HOX D;  4UVM A;  4NEJ A;  4JA3 A;  2IL6 A;  2H24 A;  4O9H A;  4YDY I;  1HWG A;  5FHX A;  4EXN A;  3DI2 A;  5IYD D;  2ILK A;  1Y6K L;  2XUT A;  3H3V E;  1ITL A;  1PV7 A;  1M4B A;  1IRL A;  1SCF A;  1QVN A;  4YPG C;  1Z92 A;  3HOZ D;  1HUW A;  1BGC A;  1RW5 A;  4GRW A;  3WCY I;  1YKB A;  1ITF A;  1HZI A;  4NKQ C;  5C4X D;  4BBR D;  3O7P A;  5IYB D;  3NCF A;  4TPJ A;  3QB1 A;  4PYP A;  3HOU D;  2B91 A;  3S9D A;  4FA8 E;  4A3E D;  3NCC A;  1GNC A;  3D85 C;  1N1F A;  4YQX A;  1AXI A;  1Y1V D;  1IL6 A;  1M48 A;  1A7M A;  4O6K A;  1EKU A;  1FG9 A;  4LEP A;  1P9M B;  1KF9 A;  4BY1 D;  3BPO A;  1ITM A;  3NPZ A;  5D72 A;  1FYH A;  5KNH I;  3D48 P;  4YBQ A;  1BCN A;  4IU8 A;  1EMR A;  1INR A;  4DKC A;  4NI9 A;  1EER A;  4GC0 A;  2Q14 A;  1M4A A;  5D58 A;  4NN6 A;  1CD9 A;  1Y6M L;  3DI3 A;  4YB9 D;  1PV6 A;  3Q1S I;  1IK0 A;  3LB6 B;  1PW4 A;  5FUC A;  1BGD A;  1NBP A;  3PO3 D;  3QT2 C;  4BBS D;  2LMS A;  2R92 D;  4A3B D;  2CYK A;  5TS9 A;  3B5K A;  3PO2 D;  3SE3 B;  3OG6 A; 
#chains in the Genus database with same CATH homology
 4D2B A;  1PW4 A;  4OAA A;  4XNJ A;  4QIQ A;  4JRE A;  4IKY A;  3O7P A;  4ZW9 A;  4GC0 A;  5A2O A;  4GBZ A;  4W6V A;  2V8N A;  4IKZ A;  4TPH A;  4D2C A;  4Q65 A;  2XUT A;  4IU9 A;  4LEP A;  5D58 A;  1PV7 A;  5EQG A;  5EQH A;  4ZWB A;  4APS A;  4OH3 A;  5A2N A;  4TPJ A;  4IKV A;  4LDS A;  3WDO A;  4IKX A;  5EQI A;  4IKW A;  4XNI A;  2Y5Y A;  4PYP A;  4GBY A;  2CFQ A;  4UVM A;  5D59 A;  3O7Q A;  5D6K A;  4D2D A;  4U4V A;  4YB9 D;  4J05 A;  4U4W A;  4JR9 A;  1PV6 A;  4TPG A;  4YBQ A;  4U4T A;  4ZYR A;  5GXB A;  4IU8 A;  4JA3 A;  4ZWC A;  5C65 A;  2CFP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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