1Y14A

Crystal structure of yeast subcomplex of rpb4 and rpb7
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
176
structure length
133
Chain Sequence
ELIALNLSEARLVIKEALVERRRAFKRSQTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords DNA-directed RNA polymerase II 32 kDa polypeptide
total genus 50
structure length 133
sequence length 176
chains with identical sequence C
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2004-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 1y14A01
2B63D 4BXXD 1WCMD 5IYBD 5C44D 4A3DD 4BY7D 5IP7D 3HOVD 4A3MD 2R93D 2JA6D 3HOUD 1Y1WD 4A3CD 4A3LD 4A3KD 4A3JD 5FLMD 5C3ED 3HOZD 4BY1D 4BBSD 3H3VE 4BBRD 1Y1VD 4A3BD 4A93D 1Y14A 3H0GD 3PO2D 3HOYD 2R7ZD 2C35A 3PO3D 3I4MD 5IP9D 2JA8D 4A3ID 2JA7D 4A3GD 4A3FD 4A3ED 3FKID 3I4ND 2R92D 3AYHA 5IYCD 2JA5D 5IYDD 3HOXD 5C4XD 2VUMD 3HOWD
chains in the Genus database with same CATH superfamily
2B63D 1NBPA 3DLQI 5IP7D 2JA6D 4EXPA 1GNCA 2B90A 4NN6A 4O9HA 5EQHA 4GS7A 2B8ZA 4A3GD 3NCFA 1YKBA 4LRLA 2HYMB 1EXZA 4NEJA 2Q14A 4YUEC 3Q1SI 4NN5A 4OAAA 1ITIA 5C44D 5A2OA 1EERA 4NEMA 4A3MD 5D72A 4A3CD 4A3KD 4PYPA 3PIWA 5FLMD 4A3BD 4NN7A 2JA8D 4TPHA 3NCCA 3PIVA 2Y5YA 1EVSA 4BXXD 4U4WA 2LMSA 2R93D 2Q7NB 2B8YA 4YBQA 2GMFA 1M4AA 1Z92A 2XUTA 5FHXA 3HOYD 5IYCD 2JA5D 4DKEA 1EMRA 3HMXB 1CD9A 3NCBA 1HIKA 4DKDA 4IKVA 1CYLA 1M49A 1F6FA 1M4CA 3L5XA 4NKQC 2L3YA 2JA7D 4WRLB 3BESL 5C4XD 1V7NV 5D70A 1ILKA 3DI2A 5GXBA 1INRA 4GC0A 4A3LD 1P9MB 2CFPA 1PW6A 3BPLA 1CSGA 2C35A 4DKCA 4YPGC 3D87A 2CYKA 3EW3A 3AYHA 4J4LC 2O26A 3O7QA 1IARA 1BBNA 3N06A 4JR9A 4ZWBA 2B8UA 1ITFA 3DGCL 5D59A 4A3JD 1LQSL 3SE3B 5KNHI 2L3OA 3VA2A 4YB9D 4BBRD 5C7XA 2E9WC 1Y6NL 3LB6A 3QAZA 1IL6A 4IKWA 1HUWA 3DUHC 1BUYA 1A7MA 2O27A 3G9VB 2H24A 3HOVD 3OG4A 4EXNA 3QT2C 5D28B 3OQ3A 4A93D 4OH3A 4U4TA 2B8XA 5IP9D 1PV6A 1M4BA 1BGDA 4XNIA 5D6KA 4TPJA 4FA8E 4ZW9A 1J7VL 1PGRA 1RFBA 3MZGA 4BBSD 1AXIA 3PO2D 4NI7A 2R7ZD 1D9CA 4D2DA 3TGXB 5IYDD 3HOXD 2CFQA 1KF9A 1WCMD 4IU9A 4CNIC 4J05A 5E4EA 4D2BA 1HGUA 3QB7A 1Y6ML 2ERJD 3FKID 3OG6A 1GA3A 3HHRA 4PS4A 3BPOA 2PSMA 2VUMD 2B5IA 3N0PA 3QB1A 5TS9A 2O6IA 1HIJA 5C3ED 4ZWCA 4XNJA 1ITLA 2IL6A 4YQXA 2Z3RA 1Y1VD 5L6YC 1EKUA 1N1FA 3L5WI 5LQBA 1M4RA 1PW4A 5A2NA 4RS1A 1VLKA 3S9DA 1PVHB 4ZS7A 1AX8A 3HOZD 1HULA 4IKYA 3D85C 4BY1D 3IRHA 3H0GD 1V7MV 4A3ID 1HZIA 2Q98A 4TPGA 5EQIA 4U4VA 1ITMA 1BGCA 3HOUD 1M48A 1HWGA 3INKC 1RHGA 5D22A 3D48P 1I1RB 4ZYRA 1RCBA 1SCFA 5D58A 3G6DA 1CN4C 4UVMA 4I77Z 4LEPA 2LAGA 1IK0A 4A3DD 4QIQA 1Z7CA 1IRLA 1BCNA 3I4MD 3QWRB 4A3FD 4Z5RD 1HWHA 1JLIA 4LDSA 2R92D 5D71A 2INTA 1M47A 1Y6KL 1D9GA 1QVNA 2OQPA 3UF5A 3SE4B 3NCEA 4IKZA 4JA3A 2Z3QA 1WU3I 3NPZA 2V8NA 1PY2A 4DKFA 4GBZA 3H3VE 1ALUA 5EQGA 1RW5A 3UF2A 2D48A 4MHLA 4ZF7A 4W6VA 4JREA 4A3ED 4Q65A 3HOWD 3LB6B 5IYBD 2ILKA 1IJZA 4BY7D 4O6KA 2D9QA 4IU8A 5C65A 1FYHA 3EJJA 3B5KA 4NI9A 3DI3A 4GRWA 4IKXA 1Y14A 4DOHA 1A22A 3WCYI 1B5LA 3UX9A 3O7PA 5FUCA 1LK3A 1LKIA 2B91A 1ETEA 3WDOA 3BPNA 4D2CA 1FG9A 1AU1A 4YDYI 1Y1WD 4GBYA 2XQBA 3UEZE 1CNT1 1F45B 1BP3A 1PV7A 4X51A 4APSA 3PO3D 3I4ND 2KZ1A 1BGEA 3HHCA
chains in the Genus database with same CATH topology
2B63D 1WCMD 1ILKA 1NBPA 3DLQI 5D70A 5IP7D 4A3DD 1IK0A 2JA6D 3DI2A 1INRA 4CNIC 4EXPA 4A3LD 1GNCA 1Z7CA 2B90A 4NN6A 5E4EA 1P9MB 4O9HA 4GS7A 1IRLA 1PW6A 4LRLA 3BPLA 1BCNA 1HGUA 1CSGA 2B8ZA 2C35A 3QB7A 3QWRB 1Y6ML 4DKCA 4YPGC 3I4MD 4A3GD 2ERJD 4A3FD 4Z5RD 3FKID 1HWHA 1YKBA 1JLIA 3D87A 3HHRA 3NCFA 2CYKA 3EW3A 3OG6A 2INTA 3AYHA 2HYMB 1M47A 1Y6KL 1EXZA 3BPOA 1D9GA 1QVNA 2PSMA 2Q14A 4J4LC 4NEJA 2VUMD 2O26A 2OQPA 1IARA 1BBNA 2B5IA 3Q1SI 4NN5A 4YUEC 3UF5A 3N06A 4PS4A 5C44D 3N0PA 3QB1A 1EERA 4NEMA 3SE4B 4A3MD 1ITIA 5TS9A 2B8UA 5D72A 3NCEA 4A3CD 1ITFA 3DGCL 2Z3QA 4A3KD 4A3JD 2O6IA 1WU3I 3PIWA 1HIJA 1LQSL 3NPZA 3SE3B 1PY2A 4DKFA 5KNHI 2L3OA 3HHCA 5FLMD 3VA2A 1ITLA 2IL6A 4YQXA 2Z3RA 3H3VE 4BBRD 1Y1VD 5C7XA 1EKUA 2E9WC 1ALUA 1Y6NL 3LB6A 1N1FA 3QAZA 5L6YC 1IL6A 1RW5A 3L5WI 2D48A 1M4RA 3UF2A 5LQBA 4MHLA 4NN7A 4ZF7A 2JA8D 1HUWA 3DUHC 1BUYA 4A3ED 1A7MA 4RS1A 3NCCA 1VLKA 3S9DA 1PVHB 2O27A 3PIVA 4ZS7A 1EVSA 3HOWD 3G9VB 4BXXD 2H24A 3LB6B 2ILKA 1IJZA 5D71A 5IYBD 4O6KA 2D9QA 3HOVD 2LMSA 4BY7D 2R93D 1AX8A 3OG4A 4EXNA 1GA3A 2Q7NB 2B8YA 1FYHA 3EJJA 1HULA 3QT2C 3HOZD 3D85C 2GMFA 1M4AA 1Z92A 4A3BD 4BY1D 3B5KA 5D28B 3DI3A 4GRWA 4NI9A 3IRHA 3OQ3A 5FHXA 1Y14A 4A93D 3H0GD 3HOYD 2B8XA 1V7MV 4DOHA 5IP9D 1M4BA 4A3ID 1A22A 3WCYI 1B5LA 3UX9A 1BGDA 1HZIA 2Q98A 5FUCA 1LK3A 1LKIA 2B91A 5IYCD 2JA5D 1ETEA 3BPNA 4DKEA 1FG9A 1EMRA 3HMXB 1ITMA 1BGCA 1CD9A 1AU1A 4FA8E 4YDYI 1J7VL 3NCBA 3HOUD 1Y1WD 1HIKA 1PGRA 1RFBA 1M48A 1HWGA 3MZGA 5C3ED 4DKDA 2XQBA 3UEZE 3INKC 1CNT1 1CYLA 1M49A 1F6FA 1RHGA 1F45B 1M4CA 1BP3A 4BBSD 1AXIA 2R92D 3L5XA 4X51A 3PO2D 4NKQC 4NI7A 2L3YA 5D22A 2R7ZD 3PO3D 3D48P 1I1RB 2JA7D 4WRLB 1RCBA 1SCFA 1D9CA 3I4ND 3G6DA 3BESL 1CN4C 3TGXB 4I77Z 2KZ1A 5IYDD 1BGEA 3HOXD 5C4XD 2LAGA 1V7NV 1KF9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B63 D;  4BXX D;  1WCM D;  5IYB D;  5C44 D;  4A3D D;  4BY7 D;  5IP7 D;  3HOV D;  4A3M D;  2R93 D;  2JA6 D;  3HOU D;  1Y1W D;  4A3C D;  4A3L D;  4A3K D;  4A3J D;  5FLM D;  5C3E D;  3HOZ D;  4BY1 D;  4BBS D;  3H3V E;  4BBR D;  1Y1V D;  4A3B D;  4A93 D;  1Y14 A;  3H0G D;  3PO2 D;  3HOY D;  2R7Z D;  2C35 A;  3PO3 D;  3I4M D;  5IP9 D;  2JA8 D;  4A3I D;  2JA7 D;  4A3G D;  4A3F D;  4A3E D;  3FKI D;  3I4N D;  2R92 D;  3AYH A;  5IYC D;  2JA5 D;  5IYD D;  3HOX D;  5C4X D;  2VUM D;  3HOW D; 
#chains in the Genus database with same CATH topology
 2B63 D;  1NBP A;  3DLQ I;  5IP7 D;  2JA6 D;  4EXP A;  1GNC A;  2B90 A;  4NN6 A;  4O9H A;  5EQH A;  4GS7 A;  2B8Z A;  4A3G D;  3NCF A;  1YKB A;  4LRL A;  2HYM B;  1EXZ A;  4NEJ A;  2Q14 A;  4YUE C;  3Q1S I;  4NN5 A;  4OAA A;  1ITI A;  5C44 D;  5A2O A;  1EER A;  4NEM A;  4A3M D;  5D72 A;  4A3C D;  4A3K D;  4PYP A;  3PIW A;  5FLM D;  4A3B D;  4NN7 A;  2JA8 D;  4TPH A;  3NCC A;  3PIV A;  2Y5Y A;  1EVS A;  4BXX D;  4U4W A;  2LMS A;  2R93 D;  2Q7N B;  2B8Y A;  4YBQ A;  2GMF A;  1M4A A;  1Z92 A;  2XUT A;  5FHX A;  3HOY D;  5IYC D;  2JA5 D;  4DKE A;  1EMR A;  3HMX B;  1CD9 A;  3NCB A;  1HIK A;  4DKD A;  4IKV A;  1CYL A;  1M49 A;  1F6F A;  1M4C A;  3L5X A;  4NKQ C;  2L3Y A;  2JA7 D;  4WRL B;  3BES L;  5C4X D;  1V7N V;  5D70 A;  1ILK A;  3DI2 A;  5GXB A;  1INR A;  4GC0 A;  4A3L D;  1P9M B;  2CFP A;  1PW6 A;  3BPL A;  1CSG A;  2C35 A;  4DKC A;  4YPG C;  3D87 A;  2CYK A;  3EW3 A;  3AYH A;  4J4L C;  2O26 A;  3O7Q A;  1IAR A;  1BBN A;  3N06 A;  4JR9 A;  4ZWB A;  2B8U A;  1ITF A;  3DGC L;  5D59 A;  4A3J D;  1LQS L;  3SE3 B;  5KNH I;  2L3O A;  3VA2 A;  4YB9 D;  4BBR D;  5C7X A;  2E9W C;  1Y6N L;  3LB6 A;  3QAZ A;  1IL6 A;  4IKW A;  1HUW A;  3DUH C;  1BUY A;  1A7M A;  2O27 A;  3G9V B;  2H24 A;  3HOV D;  3OG4 A;  4EXN A;  3QT2 C;  5D28 B;  3OQ3 A;  4A93 D;  4OH3 A;  4U4T A;  2B8X A;  5IP9 D;  1PV6 A;  1M4B A;  1BGD A;  4XNI A;  5D6K A;  4TPJ A;  4FA8 E;  4ZW9 A;  1J7V L;  1PGR A;  1RFB A;  3MZG A;  4BBS D;  1AXI A;  3PO2 D;  4NI7 A;  2R7Z D;  1D9C A;  4D2D A;  3TGX B;  5IYD D;  3HOX D;  2CFQ A;  1KF9 A;  1WCM D;  4IU9 A;  4CNI C;  4J05 A;  5E4E A;  4D2B A;  1HGU A;  3QB7 A;  1Y6M L;  2ERJ D;  3FKI D;  3OG6 A;  1GA3 A;  3HHR A;  4PS4 A;  3BPO A;  2PSM A;  2VUM D;  2B5I A;  3N0P A;  3QB1 A;  5TS9 A;  2O6I A;  1HIJ A;  5C3E D;  4ZWC A;  4XNJ A;  1ITL A;  2IL6 A;  4YQX A;  2Z3R A;  1Y1V D;  5L6Y C;  1EKU A;  1N1F A;  3L5W I;  5LQB A;  1M4R A;  1PW4 A;  5A2N A;  4RS1 A;  1VLK A;  3S9D A;  1PVH B;  4ZS7 A;  1AX8 A;  3HOZ D;  1HUL A;  4IKY A;  3D85 C;  4BY1 D;  3IRH A;  3H0G D;  1V7M V;  4A3I D;  1HZI A;  2Q98 A;  4TPG A;  5EQI A;  4U4V A;  1ITM A;  1BGC A;  3HOU D;  1M48 A;  1HWG A;  3INK C;  1RHG A;  5D22 A;  3D48 P;  1I1R B;  4ZYR A;  1RCB A;  1SCF A;  5D58 A;  3G6D A;  1CN4 C;  4UVM A;  4I77 Z;  4LEP A;  2LAG A;  1IK0 A;  4A3D D;  4QIQ A;  1Z7C A;  1IRL A;  1BCN A;  3I4M D;  3QWR B;  4A3F D;  4Z5R D;  1HWH A;  1JLI A;  4LDS A;  2R92 D;  5D71 A;  2INT A;  1M47 A;  1Y6K L;  1D9G A;  1QVN A;  2OQP A;  3UF5 A;  3SE4 B;  3NCE A;  4IKZ A;  4JA3 A;  2Z3Q A;  1WU3 I;  3NPZ A;  2V8N A;  1PY2 A;  4DKF A;  4GBZ A;  3H3V E;  1ALU A;  5EQG A;  1RW5 A;  3UF2 A;  2D48 A;  4MHL A;  4ZF7 A;  4W6V A;  4JRE A;  4A3E D;  4Q65 A;  3HOW D;  3LB6 B;  5IYB D;  2ILK A;  1IJZ A;  4BY7 D;  4O6K A;  2D9Q A;  4IU8 A;  5C65 A;  1FYH A;  3EJJ A;  3B5K A;  4NI9 A;  3DI3 A;  4GRW A;  4IKX A;  1Y14 A;  4DOH A;  1A22 A;  3WCY I;  1B5L A;  3UX9 A;  3O7P A;  5FUC A;  1LK3 A;  1LKI A;  2B91 A;  1ETE A;  3WDO A;  3BPN A;  4D2C A;  1FG9 A;  1AU1 A;  4YDY I;  1Y1W D;  4GBY A;  2XQB A;  3UEZ E;  1CNT 1;  1F45 B;  1BP3 A;  1PV7 A;  4X51 A;  4APS A;  3PO3 D;  3I4N D;  2KZ1 A;  1BGE A;  3HHC A; 
#chains in the Genus database with same CATH homology
 2B63 D;  1WCM D;  1ILK A;  1NBP A;  3DLQ I;  5D70 A;  5IP7 D;  4A3D D;  1IK0 A;  2JA6 D;  3DI2 A;  1INR A;  4CNI C;  4EXP A;  4A3L D;  1GNC A;  1Z7C A;  2B90 A;  4NN6 A;  5E4E A;  1P9M B;  4O9H A;  4GS7 A;  1IRL A;  1PW6 A;  4LRL A;  3BPL A;  1BCN A;  1HGU A;  1CSG A;  2B8Z A;  2C35 A;  3QB7 A;  3QWR B;  1Y6M L;  4DKC A;  4YPG C;  3I4M D;  4A3G D;  2ERJ D;  4A3F D;  4Z5R D;  3FKI D;  1HWH A;  1YKB A;  1JLI A;  3D87 A;  3HHR A;  3NCF A;  2CYK A;  3EW3 A;  3OG6 A;  2INT A;  3AYH A;  2HYM B;  1M47 A;  1Y6K L;  1EXZ A;  3BPO A;  1D9G A;  1QVN A;  2PSM A;  2Q14 A;  4J4L C;  4NEJ A;  2VUM D;  2O26 A;  2OQP A;  1IAR A;  1BBN A;  2B5I A;  3Q1S I;  4NN5 A;  4YUE C;  3UF5 A;  3N06 A;  4PS4 A;  5C44 D;  3N0P A;  3QB1 A;  1EER A;  4NEM A;  3SE4 B;  4A3M D;  1ITI A;  5TS9 A;  2B8U A;  5D72 A;  3NCE A;  4A3C D;  1ITF A;  3DGC L;  2Z3Q A;  4A3K D;  4A3J D;  2O6I A;  1WU3 I;  3PIW A;  1HIJ A;  1LQS L;  3NPZ A;  3SE3 B;  1PY2 A;  4DKF A;  5KNH I;  2L3O A;  3HHC A;  5FLM D;  3VA2 A;  1ITL A;  2IL6 A;  4YQX A;  2Z3R A;  3H3V E;  4BBR D;  1Y1V D;  5C7X A;  1EKU A;  2E9W C;  1ALU A;  1Y6N L;  3LB6 A;  1N1F A;  3QAZ A;  5L6Y C;  1IL6 A;  1RW5 A;  3L5W I;  2D48 A;  1M4R A;  3UF2 A;  5LQB A;  4MHL A;  4NN7 A;  4ZF7 A;  2JA8 D;  1HUW A;  3DUH C;  1BUY A;  4A3E D;  1A7M A;  4RS1 A;  3NCC A;  1VLK A;  3S9D A;  1PVH B;  2O27 A;  3PIV A;  4ZS7 A;  1EVS A;  3HOW D;  3G9V B;  4BXX D;  2H24 A;  3LB6 B;  2ILK A;  1IJZ A;  5D71 A;  5IYB D;  4O6K A;  2D9Q A;  3HOV D;  2LMS A;  4BY7 D;  2R93 D;  1AX8 A;  3OG4 A;  4EXN A;  1GA3 A;  2Q7N B;  2B8Y A;  1FYH A;  3EJJ A;  1HUL A;  3QT2 C;  3HOZ D;  3D85 C;  2GMF A;  1M4A A;  1Z92 A;  4A3B D;  4BY1 D;  3B5K A;  5D28 B;  3DI3 A;  4GRW A;  4NI9 A;  3IRH A;  3OQ3 A;  5FHX A;  1Y14 A;  4A93 D;  3H0G D;  3HOY D;  2B8X A;  1V7M V;  4DOH A;  5IP9 D;  1M4B A;  4A3I D;  1A22 A;  3WCY I;  1B5L A;  3UX9 A;  1BGD A;  1HZI A;  2Q98 A;  5FUC A;  1LK3 A;  1LKI A;  2B91 A;  5IYC D;  2JA5 D;  1ETE A;  3BPN A;  4DKE A;  1FG9 A;  1EMR A;  3HMX B;  1ITM A;  1BGC A;  1CD9 A;  1AU1 A;  4FA8 E;  4YDY I;  1J7V L;  3NCB A;  3HOU D;  1Y1W D;  1HIK A;  1PGR A;  1RFB A;  1M48 A;  1HWG A;  3MZG A;  5C3E D;  4DKD A;  2XQB A;  3UEZ E;  3INK C;  1CNT 1;  1CYL A;  1M49 A;  1F6F A;  1RHG A;  1F45 B;  1M4C A;  1BP3 A;  4BBS D;  1AXI A;  2R92 D;  3L5X A;  4X51 A;  3PO2 D;  4NKQ C;  4NI7 A;  2L3Y A;  5D22 A;  2R7Z D;  3PO3 D;  3D48 P;  1I1R B;  2JA7 D;  4WRL B;  1RCB A;  1SCF A;  1D9C A;  3I4N D;  3G6D A;  3BES L;  1CN4 C;  3TGX B;  4I77 Z;  2KZ1 A;  5IYD D;  1BGE A;  3HOX D;  5C4X D;  2LAG A;  1V7N V;  1KF9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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