2JA6D

Cpd lesion containing rna polymerase ii elongation complex b
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
218
structure length
177
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CPD damage recognition by transcribing RNA polymerase II.
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 40
structure length 177
sequence length 218
ec nomenclature
pdb deposition date 2006-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 2ja6D02
5C4XD 1WCMD 2JA5D 4A3JD 3FKID 3I4ND 5IP9D 4A3ID 4BY1D 5IYCD 3H3VE 4A3LD 3HOZD 5C3ED 3PO2D 3HOYD 5FLMD 2R7ZD 4A3GD 3AYHA 4A3ED 4BY7D 4BXXD 1Y1WD 4A3MD 5IYBD 4A3KD 2JA6D 3HOUD 2VUMD 3HOWD 4A93D 3H0GD 2C35A 3PO3D 4BBRD 3HOVD 4A3BD 2B63D 5IYDD 1Y14A 4BBSD 1Y1VD 2R92D 5IP7D 2R93D 4A3CD 4A3DD 5C44D 2JA8D 3I4MD 2JA7D 4A3FD 3HOXD
chains in the Genus database with same CATH superfamily
5D59A 4A3JD 2KZ1A 2INTA 2CFPA 3WCYI 3WDOA 1WU3I 4ZYRA 3DLQI 2ILKA 5D70A 2IL6A 2GMFA 4J05A 1D9CA 1Y6ML 1CNT1 1I1RB 4YDYI 4A3CD 1M4BA 1ETEA 3UF5A 3I4MD 4Q65A 4NN6A 4U4TA 5EQHA 5IP9D 2Z3RA 3DI2A 1BGCA 1PV6A 2B8UA 4JR9A 1A7MA 4LRLA 1D9GA 4DKDA 2JA8D 3HHRA 2JA5D 3HHCA 5E4EA 4ZWBA 4MHLA 4BY7D 1LK3A 1EKUA 4ZF7A 5A2OA 1IK0A 3H0GD 1HWGA 4YBQA 4I77Z 1BGDA 3D85C 4IKWA 5C44D 4JA3A 4LEPA 5C4XD 1WCMD 2H24A 4APSA 4IKVA 5EQIA 1CSGA 2PSMA 3HOYD 1EXZA 3L5XA 4NEJA 4DKFA 5D22A 4D2DA 3MZGA 5C7XA 4OAAA 3Q1SI 2XQBA 1HUWA 1AX8A 3NCEA 2ERJD 1HULA 5D28B 4O6KA 3DUHC 4YPGC 1ITIA 4ZW9A 3LB6A 4XNJA 4WRLB 2CFQA 3AYHA 5L6YC 4X51A 2XUTA 1IRLA 1QVNA 2VUMD 3O7QA 3OG6A 3G6DA 3INKC 3HOVD 1PGRA 5FHXA 4IKYA 2LMSA 1EERA 1Z92A 2Q14A 5IP7D 3N0PA 1YKBA 1PV7A 1JLIA 4IKZA 4DKCA 1EVSA 1B5LA 1LKIA 4BY1D 3HOZD 5D72A 1ITMA 3NCBA 2L3YA 5EQGA 3BPOA 1Y14A 4FA8E 3UX9A 2R92D 3HOXD 1FYHA 1HGUA 1IARA 4GBZA 3OG4A 1M47A 3D87A 3BESL 1J7VL 4BBRD 3QB7A 1CN4C 1M49A 4J4LC 4PS4A 1HIJA 1INRA 3H3VE 2B8ZA 2R7ZD 4A3ED 3NCFA 4IKXA 1V7NV 1M48A 1RCBA 4ZS7A 5GXBA 4A3BD 5D71A 1GA3A 1P9MB 1ILKA 2D9QA 4NI9A 2OQPA 5D6KA 2JA7D 3QB1A 3FKID 3EW3A 4NN5A 4EXNA 1IJZA 1GNCA 1HWHA 3O7PA 4IU9A 2JA6D 1ITFA 3SE4B 3S9DA 2E9WC 3PO3D 2R93D 1CYLA 1AU1A 3DI3A 2Q7NB 1N1FA 3I4ND 2CYKA 2Z3QA 2V8NA 3N06A 3G9VB 4A3MD 4QIQA 4GS7A 1HIKA 3OQ3A 5LQBA 5D58A 5A2NA 2B63D 1BGEA 1M4AA 1V7MV 4NN7A 2Y5YA 5IYCD 4A3LD 4LDSA 5C3ED 3PIVA 1BUYA 1RHGA 1A22A 3HMXB 4EXPA 3HOWD 4GBYA 1Y6KL 2B8YA 1M4RA 4YB9D 4Z5RD 1NBPA 4JREA 5C65A 1IL6A 3TGXB 3NCCA 1RW5A 3QT2C 3PO2D 1BBNA 3UEZE 4BXXD 4U4WA 1Y1WD 1EMRA 3PIWA 4NI7A 3BPNA 4TPHA 5IYBD 4A3KD 4GRWA 1PW6A 4A93D 4DOHA 5TS9A 3UF2A 4OH3A 5KNHI 3QWRB 1F6FA 5FUCA 2O26A 2LAGA 3SE3B 3L5WI 4A3GD 4YUEC 3LB6B 4IU8A 4O9HA 1BP3A 3IRHA 4DKEA 4D2BA 2B91A 1AXIA 1ITLA 3VA2A 3D48P 4UVMA 4CNIC 4RS1A 4NEMA 1PW4A 2D48A 2C35A 1BCNA 4BBSD 2L3OA 1FG9A 4A3FD 2B8XA 1SCFA 1HZIA 4GC0A 5FLMD 2HYMB 4XNIA 3NPZA 3HOUD 2B90A 4YQXA 4TPJA 1KF9A 1F45B 4U4VA 4NKQC 4D2CA 5IYDD 1M4CA 1Y1VD 1Y6NL 1VLKA 2Q98A 2B5IA 1Z7CA 3B5KA 4PYPA 4A3ID 1CD9A 3DGCL 3QAZA 4ZWCA 4TPGA 1RFBA 2O6IA 1PY2A 3EJJA 1LQSL 2O27A 1PVHB 3BPLA 4A3DD 4W6VA 1ALUA
chains in the Genus database with same CATH topology
3QB1A 4O6KA 4A3JD 3DUHC 3SE3B 3FKID 3EW3A 4NN5A 4YPGC 2KZ1A 1IJZA 2INTA 3WCYI 4EXNA 3LB6A 3L5WI 1ITIA 4A3GD 4WRLB 1GNCA 1HWHA 3AYHA 1WU3I 5L6YC 3DLQI 2ILKA 4X51A 3LB6B 4YUEC 2JA6D 1IRLA 1QVNA 5D70A 2VUMD 1ITFA 2IL6A 3OG6A 3G6DA 3INKC 3SE4B 3S9DA 4O9HA 2E9WC 3PO3D 2GMFA 1BP3A 1PGRA 3HOVD 1D9CA 3IRHA 5FHXA 2LMSA 1EERA 1Y6ML 1CNT1 1Z92A 2Q14A 4DKEA 1I1RB 2B91A 5IP7D 4YDYI 4A3CD 3N0PA 2R93D 1M4BA 1YKBA 1AXIA 1CYLA 1AU1A 1ITLA 1ETEA 3DI3A 3UF5A 1JLIA 2Q7NB 3VA2A 3I4MD 4NN6A 3D48P 4DKCA 1N1FA 1EVSA 1B5LA 1LKIA 3I4ND 5IP9D 4BY1D 2CYKA 2Z3QA 2Z3RA 4RS1A 4CNIC 3N06A 3HOZD 3G9VB 5D72A 3DI2A 1BGCA 2B8UA 4A3MD 4NEMA 1ITMA 4GS7A 1HIKA 3NCBA 2L3YA 1A7MA 3OQ3A 5LQBA 2D48A 2C35A 4LRLA 3BPOA 2B63D 1Y14A 4FA8E 3UX9A 1BCNA 4BBSD 1BGEA 2R92D 2L3OA 1FG9A 1M4AA 1V7MV 1D9GA 4DKDA 2JA8D 3HHRA 4NN7A 3HOXD 4A3FD 1FYHA 2JA5D 3HHCA 2B8XA 1HGUA 5E4EA 1SCFA 1HZIA 5IYCD 1IARA 4A3LD 3OG4A 5C3ED 5FLMD 2HYMB 4MHLA 3PIVA 1BUYA 4BY7D 1RHGA 1LK3A 1A22A 1M47A 1EKUA 3HMXB 4ZF7A 3D87A 3NPZA 4EXPA 3HOUD 2B90A 4YQXA 1KF9A 1F45B 1IK0A 3HOWD 3BESL 4NKQC 1J7VL 1Y6KL 3H0GD 2B8YA 1HWGA 1M4RA 4BBRD 3QB7A 4Z5RD 1NBPA 4I77Z 5IYDD 1BGDA 1M4CA 1Y1VD 1CN4C 1Y6NL 1M49A 1VLKA 3D85C 5C44D 2Q98A 4J4LC 1IL6A 1Z7CA 2B5IA 3TGXB 4PS4A 3NCCA 3B5KA 1RW5A 1HIJA 5C4XD 1WCMD 2H24A 3QT2C 1INRA 4A3ID 3H3VE 1CSGA 2B8ZA 3PO2D 2PSMA 1BBNA 3UEZE 3HOYD 2R7ZD 1EXZA 4A3ED 1CD9A 3L5XA 3DGCL 1EMRA 3NCFA 4NEJA 1Y1WD 4DKFA 3PIWA 4NI7A 3BPNA 3QAZA 5IYBD 4A3KD 1V7NV 1RFBA 4GRWA 1M48A 5D22A 1PW6A 1RCBA 4ZS7A 4A93D 4DOHA 2O6IA 3MZGA 5C7XA 5TS9A 4BXXD 4A3BD 1PY2A 3EJJA 5D71A 1LQSL 1P9MB 2O27A 1ILKA 3Q1SI 2D9QA 1PVHB 3UF2A 5KNHI 1GA3A 2XQBA 3QWRB 1HUWA 1AX8A 1F6FA 3BPLA 3NCEA 4NI9A 4A3DD 5FUCA 2OQPA 2O26A 2JA7D 2LAGA 2ERJD 1ALUA 1HULA 5D28B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C4X D;  1WCM D;  2JA5 D;  4A3J D;  3FKI D;  3I4N D;  5IP9 D;  4A3I D;  4BY1 D;  5IYC D;  3H3V E;  4A3L D;  3HOZ D;  5C3E D;  3PO2 D;  3HOY D;  5FLM D;  2R7Z D;  4A3G D;  3AYH A;  4A3E D;  4BY7 D;  4BXX D;  1Y1W D;  4A3M D;  5IYB D;  4A3K D;  2JA6 D;  3HOU D;  2VUM D;  3HOW D;  4A93 D;  3H0G D;  2C35 A;  3PO3 D;  4BBR D;  3HOV D;  4A3B D;  2B63 D;  5IYD D;  1Y14 A;  4BBS D;  1Y1V D;  2R92 D;  5IP7 D;  2R93 D;  4A3C D;  4A3D D;  5C44 D;  2JA8 D;  3I4M D;  2JA7 D;  4A3F D;  3HOX D; 
#chains in the Genus database with same CATH topology
 5D59 A;  4A3J D;  2KZ1 A;  2INT A;  2CFP A;  3WCY I;  3WDO A;  1WU3 I;  4ZYR A;  3DLQ I;  2ILK A;  5D70 A;  2IL6 A;  2GMF A;  4J05 A;  1D9C A;  1Y6M L;  1CNT 1;  1I1R B;  4YDY I;  4A3C D;  1M4B A;  1ETE A;  3UF5 A;  3I4M D;  4Q65 A;  4NN6 A;  4U4T A;  5EQH A;  5IP9 D;  2Z3R A;  3DI2 A;  1BGC A;  1PV6 A;  2B8U A;  4JR9 A;  1A7M A;  4LRL A;  1D9G A;  4DKD A;  2JA8 D;  3HHR A;  2JA5 D;  3HHC A;  5E4E A;  4ZWB A;  4MHL A;  4BY7 D;  1LK3 A;  1EKU A;  4ZF7 A;  5A2O A;  1IK0 A;  3H0G D;  1HWG A;  4YBQ A;  4I77 Z;  1BGD A;  3D85 C;  4IKW A;  5C44 D;  4JA3 A;  4LEP A;  5C4X D;  1WCM D;  2H24 A;  4APS A;  4IKV A;  5EQI A;  1CSG A;  2PSM A;  3HOY D;  1EXZ A;  3L5X A;  4NEJ A;  4DKF A;  5D22 A;  4D2D A;  3MZG A;  5C7X A;  4OAA A;  3Q1S I;  2XQB A;  1HUW A;  1AX8 A;  3NCE A;  2ERJ D;  1HUL A;  5D28 B;  4O6K A;  3DUH C;  4YPG C;  1ITI A;  4ZW9 A;  3LB6 A;  4XNJ A;  4WRL B;  2CFQ A;  3AYH A;  5L6Y C;  4X51 A;  2XUT A;  1IRL A;  1QVN A;  2VUM D;  3O7Q A;  3OG6 A;  3G6D A;  3INK C;  3HOV D;  1PGR A;  5FHX A;  4IKY A;  2LMS A;  1EER A;  1Z92 A;  2Q14 A;  5IP7 D;  3N0P A;  1YKB A;  1PV7 A;  1JLI A;  4IKZ A;  4DKC A;  1EVS A;  1B5L A;  1LKI A;  4BY1 D;  3HOZ D;  5D72 A;  1ITM A;  3NCB A;  2L3Y A;  5EQG A;  3BPO A;  1Y14 A;  4FA8 E;  3UX9 A;  2R92 D;  3HOX D;  1FYH A;  1HGU A;  1IAR A;  4GBZ A;  3OG4 A;  1M47 A;  3D87 A;  3BES L;  1J7V L;  4BBR D;  3QB7 A;  1CN4 C;  1M49 A;  4J4L C;  4PS4 A;  1HIJ A;  1INR A;  3H3V E;  2B8Z A;  2R7Z D;  4A3E D;  3NCF A;  4IKX A;  1V7N V;  1M48 A;  1RCB A;  4ZS7 A;  5GXB A;  4A3B D;  5D71 A;  1GA3 A;  1P9M B;  1ILK A;  2D9Q A;  4NI9 A;  2OQP A;  5D6K A;  2JA7 D;  3QB1 A;  3FKI D;  3EW3 A;  4NN5 A;  4EXN A;  1IJZ A;  1GNC A;  1HWH A;  3O7P A;  4IU9 A;  2JA6 D;  1ITF A;  3SE4 B;  3S9D A;  2E9W C;  3PO3 D;  2R93 D;  1CYL A;  1AU1 A;  3DI3 A;  2Q7N B;  1N1F A;  3I4N D;  2CYK A;  2Z3Q A;  2V8N A;  3N06 A;  3G9V B;  4A3M D;  4QIQ A;  4GS7 A;  1HIK A;  3OQ3 A;  5LQB A;  5D58 A;  5A2N A;  2B63 D;  1BGE A;  1M4A A;  1V7M V;  4NN7 A;  2Y5Y A;  5IYC D;  4A3L D;  4LDS A;  5C3E D;  3PIV A;  1BUY A;  1RHG A;  1A22 A;  3HMX B;  4EXP A;  3HOW D;  4GBY A;  1Y6K L;  2B8Y A;  1M4R A;  4YB9 D;  4Z5R D;  1NBP A;  4JRE A;  5C65 A;  1IL6 A;  3TGX B;  3NCC A;  1RW5 A;  3QT2 C;  3PO2 D;  1BBN A;  3UEZ E;  4BXX D;  4U4W A;  1Y1W D;  1EMR A;  3PIW A;  4NI7 A;  3BPN A;  4TPH A;  5IYB D;  4A3K D;  4GRW A;  1PW6 A;  4A93 D;  4DOH A;  5TS9 A;  3UF2 A;  4OH3 A;  5KNH I;  3QWR B;  1F6F A;  5FUC A;  2O26 A;  2LAG A;  3SE3 B;  3L5W I;  4A3G D;  4YUE C;  3LB6 B;  4IU8 A;  4O9H A;  1BP3 A;  3IRH A;  4DKE A;  4D2B A;  2B91 A;  1AXI A;  1ITL A;  3VA2 A;  3D48 P;  4UVM A;  4CNI C;  4RS1 A;  4NEM A;  1PW4 A;  2D48 A;  2C35 A;  1BCN A;  4BBS D;  2L3O A;  1FG9 A;  4A3F D;  2B8X A;  1SCF A;  1HZI A;  4GC0 A;  5FLM D;  2HYM B;  4XNI A;  3NPZ A;  3HOU D;  2B90 A;  4YQX A;  4TPJ A;  1KF9 A;  1F45 B;  4U4V A;  4NKQ C;  4D2C A;  5IYD D;  1M4C A;  1Y1V D;  1Y6N L;  1VLK A;  2Q98 A;  2B5I A;  1Z7C A;  3B5K A;  4PYP A;  4A3I D;  1CD9 A;  3DGC L;  3QAZ A;  4ZWC A;  4TPG A;  1RFB A;  2O6I A;  1PY2 A;  3EJJ A;  1LQS L;  2O27 A;  1PVH B;  3BPL A;  4A3D D;  4W6V A;  1ALU A; 
#chains in the Genus database with same CATH homology
 3QB1 A;  4O6K A;  4A3J D;  3DUH C;  3SE3 B;  3FKI D;  3EW3 A;  4NN5 A;  4YPG C;  2KZ1 A;  1IJZ A;  2INT A;  3WCY I;  4EXN A;  3LB6 A;  3L5W I;  1ITI A;  4A3G D;  4WRL B;  1GNC A;  1HWH A;  3AYH A;  1WU3 I;  5L6Y C;  3DLQ I;  2ILK A;  4X51 A;  3LB6 B;  4YUE C;  2JA6 D;  1IRL A;  1QVN A;  5D70 A;  2VUM D;  1ITF A;  2IL6 A;  3OG6 A;  3G6D A;  3INK C;  3SE4 B;  3S9D A;  4O9H A;  2E9W C;  3PO3 D;  2GMF A;  1BP3 A;  1PGR A;  3HOV D;  1D9C A;  3IRH A;  5FHX A;  2LMS A;  1EER A;  1Y6M L;  1CNT 1;  1Z92 A;  2Q14 A;  4DKE A;  1I1R B;  2B91 A;  5IP7 D;  4YDY I;  4A3C D;  3N0P A;  2R93 D;  1M4B A;  1YKB A;  1AXI A;  1CYL A;  1AU1 A;  1ITL A;  1ETE A;  3DI3 A;  3UF5 A;  1JLI A;  2Q7N B;  3VA2 A;  3I4M D;  4NN6 A;  3D48 P;  4DKC A;  1N1F A;  1EVS A;  1B5L A;  1LKI A;  3I4N D;  5IP9 D;  4BY1 D;  2CYK A;  2Z3Q A;  2Z3R A;  4RS1 A;  4CNI C;  3N06 A;  3HOZ D;  3G9V B;  5D72 A;  3DI2 A;  1BGC A;  2B8U A;  4A3M D;  4NEM A;  1ITM A;  4GS7 A;  1HIK A;  3NCB A;  2L3Y A;  1A7M A;  3OQ3 A;  5LQB A;  2D48 A;  2C35 A;  4LRL A;  3BPO A;  2B63 D;  1Y14 A;  4FA8 E;  3UX9 A;  1BCN A;  4BBS D;  1BGE A;  2R92 D;  2L3O A;  1FG9 A;  1M4A A;  1V7M V;  1D9G A;  4DKD A;  2JA8 D;  3HHR A;  4NN7 A;  3HOX D;  4A3F D;  1FYH A;  2JA5 D;  3HHC A;  2B8X A;  1HGU A;  5E4E A;  1SCF A;  1HZI A;  5IYC D;  1IAR A;  4A3L D;  3OG4 A;  5C3E D;  5FLM D;  2HYM B;  4MHL A;  3PIV A;  1BUY A;  4BY7 D;  1RHG A;  1LK3 A;  1A22 A;  1M47 A;  1EKU A;  3HMX B;  4ZF7 A;  3D87 A;  3NPZ A;  4EXP A;  3HOU D;  2B90 A;  4YQX A;  1KF9 A;  1F45 B;  1IK0 A;  3HOW D;  3BES L;  4NKQ C;  1J7V L;  1Y6K L;  3H0G D;  2B8Y A;  1HWG A;  1M4R A;  4BBR D;  3QB7 A;  4Z5R D;  1NBP A;  4I77 Z;  5IYD D;  1BGD A;  1M4C A;  1Y1V D;  1CN4 C;  1Y6N L;  1M49 A;  1VLK A;  3D85 C;  5C44 D;  2Q98 A;  4J4L C;  1IL6 A;  1Z7C A;  2B5I A;  3TGX B;  4PS4 A;  3NCC A;  3B5K A;  1RW5 A;  1HIJ A;  5C4X D;  1WCM D;  2H24 A;  3QT2 C;  1INR A;  4A3I D;  3H3V E;  1CSG A;  2B8Z A;  3PO2 D;  2PSM A;  1BBN A;  3UEZ E;  3HOY D;  2R7Z D;  1EXZ A;  4A3E D;  1CD9 A;  3L5X A;  3DGC L;  1EMR A;  3NCF A;  4NEJ A;  1Y1W D;  4DKF A;  3PIW A;  4NI7 A;  3BPN A;  3QAZ A;  5IYB D;  4A3K D;  1V7N V;  1RFB A;  4GRW A;  1M48 A;  5D22 A;  1PW6 A;  1RCB A;  4ZS7 A;  4A93 D;  4DOH A;  2O6I A;  3MZG A;  5C7X A;  5TS9 A;  4BXX D;  4A3B D;  1PY2 A;  3EJJ A;  5D71 A;  1LQS L;  1P9M B;  2O27 A;  1ILK A;  3Q1S I;  2D9Q A;  1PVH B;  3UF2 A;  5KNH I;  1GA3 A;  2XQB A;  3QWR B;  1HUW A;  1AX8 A;  1F6F A;  3BPL A;  3NCE A;  4NI9 A;  4A3D D;  5FUC A;  2OQP A;  2O26 A;  2JA7 D;  2LAG A;  2ERJ D;  1ALU A;  1HUL A;  5D28 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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