2JA7D

Cpd lesion containing rna polymerase ii elongation complex c
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
218
structure length
177
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
publication title Cpd Damage Recognition by Transcribing RNA Polymerase II.
pubmed doi rcsb
molecule keywords 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3'
total genus 38
structure length 177
sequence length 218
chains with identical sequence P
ec nomenclature
pdb deposition date 2006-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 2ja7D02
4A3MD 3H3VE 2C35A 5IYDD 3HOUD 4A3DD 4BY7D 2JA8D 4A93D 3PO3D 4BY1D 3AYHA 2JA6D 4A3ED 1Y14A 2R7ZD 4A3CD 5IYCD 3HOXD 3HOVD 3HOYD 4A3LD 3HOZD 5FLMD 1Y1WD 4A3FD 4A3KD 1WCMD 3HOWD 4BBRD 5IP9D 5C44D 4A3GD 5C4XD 3H0GD 4A3JD 5IP7D 2JA5D 3I4ND 2VUMD 3I4MD 2R93D 3FKID 2B63D 2R92D 4A3BD 4BBSD 2JA7D 1Y1VD 4BXXD 4A3ID 5IYBD 3PO2D 5C3ED
chains in the Genus database with same CATH superfamily
1IK0A 1INRA 3QT2C 1PY2A 2Q98A 1PGRA 2Q7NB 4PYPA 4NN7A 5TS9A 4ZS7A 2CYKA 3L5WI 3BPNA 4U4TA 1EMRA 4EXNA 4A3ID 3MZGA 1F45B 1HGUA 2L3YA 4IKXA 3TGXB 1IRLA 1Y6KL 5LQBA 3INKC 4YPGC 2R92D 4WRLB 4IKYA 2D48A 3SE3B 1D9GA 2H24A 3PIWA 4TPHA 3AYHA 4A3ED 1KF9A 5A2OA 1AX8A 4I77Z 3BPLA 2O26A 1A7MA 1AXIA 1NBPA 4LDSA 4BBRD 4A3GD 1M4AA 4IKWA 3OG6A 5D58A 1BCNA 4DKDA 4A3BD 2JA7D 3VA2A 3OQ3A 4NI9A 4DKFA 1CN4C 1CYLA 1GA3A 1AU1A 4D2CA 2O27A 4J05A 3QAZA 2D9QA 3NPZA 4JR9A 4IKVA 1A22A 1PW4A 1FYHA 4NKQC 3WCYI 1SCFA 4GC0A 4CNIC 4D2DA 2E9WC 3HOUD 5KNHI 1BP3A 1QVNA 1HZIA 4U4WA 5D72A 4YBQA 3HOVD 4DOHA 5C65A 3NCEA 1Y1WD 4UVMA 4TPGA 2Y5YA 4O9HA 4XNIA 1HUWA 1IARA 4NEJA 3DLQI 2INTA 4A3MD 1BUYA 1EKUA 1BGDA 2ERJD 2B8YA 2CFPA 4JREA 3HOXD 2ILKA 5L6YC 1M49A 5EQGA 3N06A 5IP7D 3WDOA 2B91A 3UEZE 3O7QA 2C35A 1ALUA 4A3DD 4GBZA 1BGCA 1Z7CA 1CSGA 1YKBA 1HULA 3HHCA 1IJZA 4QIQA 4IU9A 4OH3A 2JA5D 3I4ND 3I4MD 3D48P 4EXPA 4PS4A 4IU8A 2LMSA 2GMFA 1HWGA 1FG9A 1GNCA 4ZW9A 5FHXA 2B8ZA 1ETEA 1RW5A 4RS1A 3UF2A 3L5XA 1RCBA 1F6FA 3BESL 2JA6D 4O6KA 1PV7A 2XQBA 1BGEA 4A3KD 3N0PA 1EXZA 4GS7A 3SE4B 1PV6A 4BBSD 1ITLA 1V7NV 1CD9A 1HIJA 1D9CA 4JA3A 3H3VE 4W6VA 5IYDD 4BY7D 4A93D 5C7XA 4ZWCA 1Y14A 1IL6A 3QWRB 5D59A 4DKEA 3DI2A 4A3FD 3DGCL 1WCMD 4FA8E 3H0GD 1LKIA 3QB7A 1BBNA 5EQHA 1LQSL 3PO2D 4ZF7A 2KZ1A 2JA8D 1RHGA 2R7ZD 1ITFA 1ITIA 4A3LD 1EERA 3HOWD 2Q14A 1JLIA 1VLKA 4YUEC 1Y6NL 1Z92A 2OQPA 5IYBD 4TPJA 4OAAA 4NN6A 3LB6A 2Z3RA 4BY1D 3IRHA 5A2NA 4DKCA 1M47A 1HIKA 3S9DA 1EVSA 2V8NA 1I1RB 2B90A 1RFBA 5EQIA 3B5KA 1V7MV 3OG4A 1Y1VD 4APSA 1HWHA 3NCCA 2CFQA 3PIVA 3UF5A 1P9MB 3PO3D 5D71A 4D2BA 3Q1SI 5IYCD 4NEMA 3LB6B 4NI7A 3HMXB 3HOZD 2B8UA 5FLMD 2B5IA 5D70A 3G6DA 3NCFA 1B5LA 3G9VB 1PVHB 3O7PA 2B8XA 1PW6A 3NCBA 3UX9A 5D22A 4Q65A 2LAGA 3D87A 2PSMA 2L3OA 1Y6ML 1M48A 3HOYD 4YB9D 4Z5RD 1M4CA 4NN5A 5E4EA 4U4VA 4ZYRA 4XNJA 4X51A 3HHRA 1M4RA 3QB1A 3DI3A 1ITMA 4LEPA 3D85C 4GBYA 5IP9D 5D28B 5C4XD 4LRLA 1M4BA 4GRWA 3FKID 5D6KA 4BXXD 4YQXA 1CNT1 1LK3A 4YDYI 4J4LC 1WU3I 4MHLA 5GXBA 5FUCA 4A3CD 3DUHC 2XUTA 2HYMB 3EW3A 3BPOA 1ILKA 1J7VL 4ZWBA 2IL6A 2Z3QA 1N1FA 5C44D 3EJJA 4A3JD 2VUMD 2R93D 2O6IA 2B63D 4IKZA 5C3ED
chains in the Genus database with same CATH topology
3L5XA 3NCCA 3PIVA 1RCBA 3UF5A 1F6FA 2E9WC 1P9MB 3HOUD 5KNHI 3PO3D 1IK0A 3BESL 1INRA 5D71A 3QT2C 1BP3A 1PY2A 1HZIA 1QVNA 2Q98A 2JA6D 4O6KA 3Q1SI 5IYCD 4NEMA 1PGRA 3LB6B 5D72A 4NI7A 3HOVD 3HMXB 2Q7NB 4DOHA 3HOZD 2B8UA 3NCEA 2XQBA 1BGEA 5FLMD 1Y1WD 2B5IA 4A3KD 4NN7A 5D70A 5TS9A 3N0PA 4ZS7A 2CYKA 3G6DA 3L5WI 1EXZA 3NCFA 4GS7A 3SE4B 1B5LA 4O9HA 3BPNA 1HUWA 3G9VB 1PVHB 4BBSD 1ITLA 2B8XA 1IARA 1PW6A 3NCBA 1EMRA 5D22A 1V7NV 3UX9A 4EXNA 4A3ID 2LAGA 1CD9A 1HIJA 3MZGA 4NEJA 3DLQI 1D9CA 2INTA 4A3MD 3H3VE 3D87A 1BUYA 1EKUA 2PSMA 5IYDD 4BY7D 4A93D 1F45B 1HGUA 1BGDA 5C7XA 1Y14A 2L3YA 2L3OA 1IL6A 1Y6ML 2ERJD 3QWRB 2B8YA 1M48A 3HOXD 3HOYD 4DKEA 3TGXB 3DI2A 1IRLA 2ILKA 5L6YC 1M49A 4Z5RD 4A3FD 1Y6KL 3DGCL 1WCMD 4FA8E 1M4CA 3N06A 3H0GD 4NN5A 5LQBA 1LKIA 5IP7D 3INKC 3QB7A 5E4EA 4YPGC 1BBNA 2B91A 2R92D 4WRLB 1LQSL 3UEZE 3PO2D 2D48A 3SE3B 1D9GA 2C35A 2H24A 2KZ1A 1ALUA 4ZF7A 4A3DD 2JA8D 3PIWA 4X51A 1RHGA 3AYHA 3HHRA 1M4RA 4A3ED 1KF9A 2R7ZD 1AX8A 1ITFA 1ITIA 4A3LD 3QB1A 1BGCA 1EERA 1Z7CA 1CSGA 3DI3A 1YKBA 4I77Z 1ITMA 1HULA 3HHCA 1IJZA 3BPLA 3D85C 2O26A 1A7MA 1AXIA 1NBPA 2Q14A 3HOWD 1JLIA 4BBRD 5D28B 5IP9D 4A3GD 5C4XD 1M4AA 1VLKA 2JA5D 4YUEC 4LRLA 3I4ND 3I4MD 1M4BA 1Y6NL 3D48P 1Z92A 3FKID 3OG6A 4GRWA 4DKDA 1BCNA 4A3BD 4BXXD 2JA7D 2OQPA 5IYBD 3VA2A 4YQXA 4EXPA 4PS4A 1CNT1 3OQ3A 1LK3A 4NN6A 4NI9A 3LB6A 2Z3RA 4YDYI 3IRHA 2LMSA 1CN4C 4J4LC 4DKFA 1WU3I 4MHLA 4BY1D 1CYLA 5FUCA 4A3CD 4DKCA 1GA3A 1M47A 2GMFA 1AU1A 2O27A 1HWGA 3DUHC 1FG9A 2HYMB 3EW3A 3QAZA 1HIKA 2D9QA 3BPOA 1ILKA 3NPZA 1J7VL 3S9DA 1EVSA 1A22A 2IL6A 2Z3QA 1FYHA 1N1FA 1I1RB 1GNCA 5C44D 2B90A 1RFBA 3EJJA 4NKQC 4A3JD 5FHXA 2VUMD 2B8ZA 3B5KA 1ETEA 3WCYI 2O6IA 2R93D 1SCFA 1RW5A 1V7MV 3OG4A 4RS1A 4CNIC 2B63D 1Y1VD 3UF2A 5C3ED 1HWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3M D;  3H3V E;  2C35 A;  5IYD D;  3HOU D;  4A3D D;  4BY7 D;  2JA8 D;  4A93 D;  3PO3 D;  4BY1 D;  3AYH A;  2JA6 D;  4A3E D;  1Y14 A;  2R7Z D;  4A3C D;  5IYC D;  3HOX D;  3HOV D;  3HOY D;  4A3L D;  3HOZ D;  5FLM D;  1Y1W D;  4A3F D;  4A3K D;  1WCM D;  3HOW D;  4BBR D;  5IP9 D;  5C44 D;  4A3G D;  5C4X D;  3H0G D;  4A3J D;  5IP7 D;  2JA5 D;  3I4N D;  2VUM D;  3I4M D;  2R93 D;  3FKI D;  2B63 D;  2R92 D;  4A3B D;  4BBS D;  2JA7 D;  1Y1V D;  4BXX D;  4A3I D;  5IYB D;  3PO2 D;  5C3E D; 
#chains in the Genus database with same CATH topology
 1IK0 A;  1INR A;  3QT2 C;  1PY2 A;  2Q98 A;  1PGR A;  2Q7N B;  4PYP A;  4NN7 A;  5TS9 A;  4ZS7 A;  2CYK A;  3L5W I;  3BPN A;  4U4T A;  1EMR A;  4EXN A;  4A3I D;  3MZG A;  1F45 B;  1HGU A;  2L3Y A;  4IKX A;  3TGX B;  1IRL A;  1Y6K L;  5LQB A;  3INK C;  4YPG C;  2R92 D;  4WRL B;  4IKY A;  2D48 A;  3SE3 B;  1D9G A;  2H24 A;  3PIW A;  4TPH A;  3AYH A;  4A3E D;  1KF9 A;  5A2O A;  1AX8 A;  4I77 Z;  3BPL A;  2O26 A;  1A7M A;  1AXI A;  1NBP A;  4LDS A;  4BBR D;  4A3G D;  1M4A A;  4IKW A;  3OG6 A;  5D58 A;  1BCN A;  4DKD A;  4A3B D;  2JA7 D;  3VA2 A;  3OQ3 A;  4NI9 A;  4DKF A;  1CN4 C;  1CYL A;  1GA3 A;  1AU1 A;  4D2C A;  2O27 A;  4J05 A;  3QAZ A;  2D9Q A;  3NPZ A;  4JR9 A;  4IKV A;  1A22 A;  1PW4 A;  1FYH A;  4NKQ C;  3WCY I;  1SCF A;  4GC0 A;  4CNI C;  4D2D A;  2E9W C;  3HOU D;  5KNH I;  1BP3 A;  1QVN A;  1HZI A;  4U4W A;  5D72 A;  4YBQ A;  3HOV D;  4DOH A;  5C65 A;  3NCE A;  1Y1W D;  4UVM A;  4TPG A;  2Y5Y A;  4O9H A;  4XNI A;  1HUW A;  1IAR A;  4NEJ A;  3DLQ I;  2INT A;  4A3M D;  1BUY A;  1EKU A;  1BGD A;  2ERJ D;  2B8Y A;  2CFP A;  4JRE A;  3HOX D;  2ILK A;  5L6Y C;  1M49 A;  5EQG A;  3N06 A;  5IP7 D;  3WDO A;  2B91 A;  3UEZ E;  3O7Q A;  2C35 A;  1ALU A;  4A3D D;  4GBZ A;  1BGC A;  1Z7C A;  1CSG A;  1YKB A;  1HUL A;  3HHC A;  1IJZ A;  4QIQ A;  4IU9 A;  4OH3 A;  2JA5 D;  3I4N D;  3I4M D;  3D48 P;  4EXP A;  4PS4 A;  4IU8 A;  2LMS A;  2GMF A;  1HWG A;  1FG9 A;  1GNC A;  4ZW9 A;  5FHX A;  2B8Z A;  1ETE A;  1RW5 A;  4RS1 A;  3UF2 A;  3L5X A;  1RCB A;  1F6F A;  3BES L;  2JA6 D;  4O6K A;  1PV7 A;  2XQB A;  1BGE A;  4A3K D;  3N0P A;  1EXZ A;  4GS7 A;  3SE4 B;  1PV6 A;  4BBS D;  1ITL A;  1V7N V;  1CD9 A;  1HIJ A;  1D9C A;  4JA3 A;  3H3V E;  4W6V A;  5IYD D;  4BY7 D;  4A93 D;  5C7X A;  4ZWC A;  1Y14 A;  1IL6 A;  3QWR B;  5D59 A;  4DKE A;  3DI2 A;  4A3F D;  3DGC L;  1WCM D;  4FA8 E;  3H0G D;  1LKI A;  3QB7 A;  1BBN A;  5EQH A;  1LQS L;  3PO2 D;  4ZF7 A;  2KZ1 A;  2JA8 D;  1RHG A;  2R7Z D;  1ITF A;  1ITI A;  4A3L D;  1EER A;  3HOW D;  2Q14 A;  1JLI A;  1VLK A;  4YUE C;  1Y6N L;  1Z92 A;  2OQP A;  5IYB D;  4TPJ A;  4OAA A;  4NN6 A;  3LB6 A;  2Z3R A;  4BY1 D;  3IRH A;  5A2N A;  4DKC A;  1M47 A;  1HIK A;  3S9D A;  1EVS A;  2V8N A;  1I1R B;  2B90 A;  1RFB A;  5EQI A;  3B5K A;  1V7M V;  3OG4 A;  1Y1V D;  4APS A;  1HWH A;  3NCC A;  2CFQ A;  3PIV A;  3UF5 A;  1P9M B;  3PO3 D;  5D71 A;  4D2B A;  3Q1S I;  5IYC D;  4NEM A;  3LB6 B;  4NI7 A;  3HMX B;  3HOZ D;  2B8U A;  5FLM D;  2B5I A;  5D70 A;  3G6D A;  3NCF A;  1B5L A;  3G9V B;  1PVH B;  3O7P A;  2B8X A;  1PW6 A;  3NCB A;  3UX9 A;  5D22 A;  4Q65 A;  2LAG A;  3D87 A;  2PSM A;  2L3O A;  1Y6M L;  1M48 A;  3HOY D;  4YB9 D;  4Z5R D;  1M4C A;  4NN5 A;  5E4E A;  4U4V A;  4ZYR A;  4XNJ A;  4X51 A;  3HHR A;  1M4R A;  3QB1 A;  3DI3 A;  1ITM A;  4LEP A;  3D85 C;  4GBY A;  5IP9 D;  5D28 B;  5C4X D;  4LRL A;  1M4B A;  4GRW A;  3FKI D;  5D6K A;  4BXX D;  4YQX A;  1CNT 1;  1LK3 A;  4YDY I;  4J4L C;  1WU3 I;  4MHL A;  5GXB A;  5FUC A;  4A3C D;  3DUH C;  2XUT A;  2HYM B;  3EW3 A;  3BPO A;  1ILK A;  1J7V L;  4ZWB A;  2IL6 A;  2Z3Q A;  1N1F A;  5C44 D;  3EJJ A;  4A3J D;  2VUM D;  2R93 D;  2O6I A;  2B63 D;  4IKZ A;  5C3E D; 
#chains in the Genus database with same CATH homology
 3L5X A;  3NCC A;  3PIV A;  1RCB A;  3UF5 A;  1F6F A;  2E9W C;  1P9M B;  3HOU D;  5KNH I;  3PO3 D;  1IK0 A;  3BES L;  1INR A;  5D71 A;  3QT2 C;  1BP3 A;  1PY2 A;  1HZI A;  1QVN A;  2Q98 A;  2JA6 D;  4O6K A;  3Q1S I;  5IYC D;  4NEM A;  1PGR A;  3LB6 B;  5D72 A;  4NI7 A;  3HOV D;  3HMX B;  2Q7N B;  4DOH A;  3HOZ D;  2B8U A;  3NCE A;  2XQB A;  1BGE A;  5FLM D;  1Y1W D;  2B5I A;  4A3K D;  4NN7 A;  5D70 A;  5TS9 A;  3N0P A;  4ZS7 A;  2CYK A;  3G6D A;  3L5W I;  1EXZ A;  3NCF A;  4GS7 A;  3SE4 B;  1B5L A;  4O9H A;  3BPN A;  1HUW A;  3G9V B;  1PVH B;  4BBS D;  1ITL A;  2B8X A;  1IAR A;  1PW6 A;  3NCB A;  1EMR A;  5D22 A;  1V7N V;  3UX9 A;  4EXN A;  4A3I D;  2LAG A;  1CD9 A;  1HIJ A;  3MZG A;  4NEJ A;  3DLQ I;  1D9C A;  2INT A;  4A3M D;  3H3V E;  3D87 A;  1BUY A;  1EKU A;  2PSM A;  5IYD D;  4BY7 D;  4A93 D;  1F45 B;  1HGU A;  1BGD A;  5C7X A;  1Y14 A;  2L3Y A;  2L3O A;  1IL6 A;  1Y6M L;  2ERJ D;  3QWR B;  2B8Y A;  1M48 A;  3HOX D;  3HOY D;  4DKE A;  3TGX B;  3DI2 A;  1IRL A;  2ILK A;  5L6Y C;  1M49 A;  4Z5R D;  4A3F D;  1Y6K L;  3DGC L;  1WCM D;  4FA8 E;  1M4C A;  3N06 A;  3H0G D;  4NN5 A;  5LQB A;  1LKI A;  5IP7 D;  3INK C;  3QB7 A;  5E4E A;  4YPG C;  1BBN A;  2B91 A;  2R92 D;  4WRL B;  1LQS L;  3UEZ E;  3PO2 D;  2D48 A;  3SE3 B;  1D9G A;  2C35 A;  2H24 A;  2KZ1 A;  1ALU A;  4ZF7 A;  4A3D D;  2JA8 D;  3PIW A;  4X51 A;  1RHG A;  3AYH A;  3HHR A;  1M4R A;  4A3E D;  1KF9 A;  2R7Z D;  1AX8 A;  1ITF A;  1ITI A;  4A3L D;  3QB1 A;  1BGC A;  1EER A;  1Z7C A;  1CSG A;  3DI3 A;  1YKB A;  4I77 Z;  1ITM A;  1HUL A;  3HHC A;  1IJZ A;  3BPL A;  3D85 C;  2O26 A;  1A7M A;  1AXI A;  1NBP A;  2Q14 A;  3HOW D;  1JLI A;  4BBR D;  5D28 B;  5IP9 D;  4A3G D;  5C4X D;  1M4A A;  1VLK A;  2JA5 D;  4YUE C;  4LRL A;  3I4N D;  3I4M D;  1M4B A;  1Y6N L;  3D48 P;  1Z92 A;  3FKI D;  3OG6 A;  4GRW A;  4DKD A;  1BCN A;  4A3B D;  4BXX D;  2JA7 D;  2OQP A;  5IYB D;  3VA2 A;  4YQX A;  4EXP A;  4PS4 A;  1CNT 1;  3OQ3 A;  1LK3 A;  4NN6 A;  4NI9 A;  3LB6 A;  2Z3R A;  4YDY I;  3IRH A;  2LMS A;  1CN4 C;  4J4L C;  4DKF A;  1WU3 I;  4MHL A;  4BY1 D;  1CYL A;  5FUC A;  4A3C D;  4DKC A;  1GA3 A;  1M47 A;  2GMF A;  1AU1 A;  2O27 A;  1HWG A;  3DUH C;  1FG9 A;  2HYM B;  3EW3 A;  3QAZ A;  1HIK A;  2D9Q A;  3BPO A;  1ILK A;  3NPZ A;  1J7V L;  3S9D A;  1EVS A;  1A22 A;  2IL6 A;  2Z3Q A;  1FYH A;  1N1F A;  1I1R B;  1GNC A;  5C44 D;  2B90 A;  1RFB A;  3EJJ A;  4NKQ C;  4A3J D;  5FHX A;  2VUM D;  2B8Z A;  3B5K A;  1ETE A;  3WCY I;  2O6I A;  2R93 D;  1SCF A;  1RW5 A;  1V7M V;  3OG4 A;  4RS1 A;  4CNI C;  2B63 D;  1Y1V D;  3UF2 A;  5C3E D;  1HWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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