2JA6D

Cpd lesion containing rna polymerase ii elongation complex b
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
218
structure length
177
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CPD damage recognition by transcribing RNA polymerase II.
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 40
structure length 177
sequence length 218
ec nomenclature
pdb deposition date 2006-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 2ja6D02
5C4XD 5IP7D 5IYBD 5IYCD 5C44D 4A3GD 3I4MD 3PO2D 3H3VE 2R7ZD 2R93D 4A3JD 4A3MD 1WCMD 5IP9D 3I4ND 3AYHA 4A3LD 4A3ED 2R92D 5C3ED 2JA6D 5FLMD 4BY7D 4BXXD 3HOUD 5IYDD 2JA8D 3H0GD 4A3FD 4A93D 4BBSD 4A3KD 3HOYD 4A3DD 1Y1VD 3HOXD 2JA7D 3HOVD 4A3ID 1Y1WD 4A3BD 2JA5D 3HOWD 2VUMD 3HOZD 2B63D 2C35A 1Y14A 4BY1D 4BBRD 4A3CD 3FKID 3PO3D
chains in the Genus database with same CATH superfamily
4IKVA 1CD9A 1IRLA 4GBYA 5D59A 1INRA 3NPZA 2LAGA 1JLIA 4W6VA 5C7XA 1IJZA 1M4AA 1BGEA 1PY2A 2GMFA 1D9GA 3PO3D 2Q14A 1ITIA 1PV7A 3LB6A 3DI3A 4XNIA 5L6YC 3D48P 3AYHA 1M48A 2B8XA 3DI2A 1AX8A 1B5LA 4UVMA 4O6KA 1LKIA 1CSGA 1Y1WD 1GNCA 1CNT1 2O26A 1FG9A 4XNJA 4CNIC 4IKWA 4D2CA 3UEZE 1RCBA 4TPGA 4PYPA 3BPOA 4U4WA 2B8YA 2VUMD 4ZF7A 5IYBD 4YDYI 4OAAA 4BBRD 1M47A 5IP9D 4NN7A 4ZS7A 3BPLA 2XQBA 3HOYD 4LEPA 2XUTA 4A3ID 1AXIA 4DKCA 5D22A 3DGCL 1BGDA 1HIJA 2B5IA 5D6KA 1ALUA 5A2NA 1ETEA 2O27A 2D48A 1HWHA 3D85C 3DUHC 1I1RB 4NI9A 4IKXA 1IK0A 1EERA 2LMSA 3OG6A 4A3BD 1EKUA 2JA5D 4BY1D 2KZ1A 1Y14A 4DKDA 1ITMA 3MZGA 3H3VE 5EQGA 4U4TA 2Z3QA 4DKFA 4NI7A 1FYHA 1AU1A 4NN5A 3NCCA 2C35A 3HMXB 4A3CD 1V7NV 2L3YA 3QWRB 5D70A 3SE4B 2OQPA 1HGUA 3I4ND 2D9QA 3HOUD 1HZIA 4WRLB 4U4VA 3H0GD 4A3KD 4A3DD 1Y1VD 4IKZA 3OQ3A 4YUEC 1CYLA 4ZYRA 1EVSA 1WU3I 2V8NA 3G9VB 1BP3A 4YBQA 3PO2D 3OG4A 1HULA 3WCYI 4A3MD 1WCMD 4LDSA 1BUYA 1RHGA 5D71A 4NEJA 3UF2A 1RFBA 5D72A 4Q65A 1Y6NL 1HWGA 3SE3B 3FKID 5C4XD 1F6FA 1D9CA 1EXZA 2ERJD 1Y6ML 4NEMA 4NN6A 1EMRA 4FA8E 5E4EA 3EW3A 2R92D 5C3ED 2JA6D 4A3FD 4GRWA 3PIWA 1VLKA 1BBNA 2CFPA 1ITFA 1V7MV 3QB7A 2E9WC 2Q98A 2ILKA 1M4BA 4OH3A 5EQIA 2R93D 2O6IA 1F45B 5FHXA 5FLMD 3TGXB 4D2BA 1PW4A 3QB1A 1M49A 3BESL 5GXBA 4IKYA 4GBZA 4GS7A 1KF9A 4DOHA 4A3LD 3L5XA 3N0PA 3DLQI 1BGCA 1SCFA 4BBSD 5D58A 3B5KA 1PV6A 4TPJA 1HUWA 4LRLA 3BPNA 4ZWCA 4ZWBA 4EXNA 2R7ZD 3O7QA 3VA2A 4JA3A 4A3ED 4BY7D 3UF5A 5D28B 1PW6A 1LK3A 2B8UA 3LB6B 4IU8A 3D87A 3QT2C 2B63D 1BCNA 2INTA 1IARA 3L5WI 5EQHA 4TPHA 3I4MD 2H24A 4J4LC 4DKEA 1A22A 1QVNA 5TS9A 3UX9A 1A7MA 2CFQA 3HOVD 3WDOA 4YQXA 1P9MB 2L3OA 4A3GD 3NCFA 1ITLA 5C65A 1M4RA 5IYCD 4QIQA 3N06A 4MHLA 3PIVA 1HIKA 4A3JD 5A2OA 4YPGC 5IYDD 5LQBA 4JR9A 4A93D 1CN4C 2Z3RA 1M4CA 4APSA 4J05A 2IL6A 1PVHB 1GA3A 1NBPA 4I77Z 5C44D 3IRHA 1PGRA 1Y6KL 4JREA 3EJJA 4YB9D 4NKQC 1Z7CA 4O9HA 3O7PA 5FUCA 2JA8D 4GC0A 1J7VL 2JA7D 2PSMA 4Z5RD 3NCEA 2B91A 3HOZD 3INKC 1YKBA 5IP7D 1N1FA 4EXPA 3S9DA 2HYMB 2B90A 3Q1SI 5KNHI 4PS4A 2B8ZA 1IL6A 3QAZA 4IU9A 2CYKA 1ILKA 4BXXD 4RS1A 1LQSL 3HHRA 1RW5A 3NCBA 2Y5YA 3G6DA 3HOXD 4ZW9A 2Q7NB 3HOWD 4D2DA 4X51A 3HHCA 1Z92A
chains in the Genus database with same CATH topology
5C4XD 1ALUA 1F6FA 1D9CA 1CD9A 1ETEA 2O27A 3L5WI 1IRLA 3I4MD 1EXZA 2H24A 2D48A 1HWHA 4J4LC 1INRA 3D85C 4DKEA 3DUHC 1A22A 3NPZA 2ERJD 1Y6ML 1I1RB 4NEMA 4NN6A 4NI9A 1EMRA 4FA8E 5E4EA 2LAGA 1QVNA 3EW3A 5C3ED 2JA6D 2R92D 1JLIA 5TS9A 3UX9A 5C7XA 4GRWA 4A3FD 3PIWA 1A7MA 1IJZA 1M4AA 1IK0A 1EERA 1VLKA 1BGEA 2LMSA 3HOVD 1BBNA 1ITFA 3OG6A 1PY2A 1V7MV 2GMFA 3QB7A 4YQXA 1P9MB 4A3BD 1D9GA 1EKUA 2JA5D 2L3OA 2E9WC 2Q98A 4BY1D 4A3GD 2KZ1A 1Y14A 3PO3D 2ILKA 3NCFA 1ITLA 5IYCD 1M4RA 2Q14A 4DKDA 1M4BA 1ITIA 3N06A 1ITMA 3LB6A 4MHLA 3MZGA 3DI3A 3PIVA 1HIKA 5L6YC 3H3VE 4A3JD 2R93D 3D48P 2O6IA 1F45B 1M48A 2B8XA 3AYHA 5FHXA 3DI2A 5FLMD 4YPGC 3TGXB 1AX8A 5IYDD 1B5LA 5LQBA 4A93D 1CN4C 4O6KA 2Z3RA 1LKIA 1M4CA 2Z3QA 3HHCA 4NI7A 4DKFA 1CSGA 1FYHA 1AU1A 1Y1WD 1GNCA 3QB1A 4NN5A 1M49A 3NCCA 1CNT1 2C35A 2IL6A 2O26A 3HMXB 4A3CD 3BESL 1PVHB 1GA3A 1NBPA 1V7NV 4I77Z 2L3YA 3QWRB 5C44D 3IRHA 1FG9A 1PGRA 1Y6KL 5D70A 4CNIC 3EJJA 3SE4B 2OQPA 1HGUA 4GS7A 4NKQC 1Z7CA 4BXXD 3I4ND 1KF9A 4DOHA 4O9HA 3UEZE 4A3LD 3L5XA 3N0PA 5FUCA 3DLQI 1BGCA 2D9QA 3HOUD 1HZIA 1SCFA 1RCBA 4WRLB 2JA8D 3H0GD 1J7VL 4BBSD 4A3KD 4A3DD 1Y1VD 2JA7D 3BPOA 2PSMA 3OQ3A 4YUEC 1CYLA 4Z5RD 1EVSA 1WU3I 2B91A 3NCEA 2B8YA 3B5KA 3G9VB 3HOZD 2VUMD 1HUWA 4LRLA 4ZF7A 3INKC 1YKBA 5IP7D 1N1FA 1BP3A 5IYBD 2INTA 4EXPA 3S9DA 4YDYI 3BPNA 2HYMB 2B90A 4EXNA 4BBRD 3PO2D 3OG4A 1M47A 2R7ZD 1HULA 3Q1SI 3WCYI 5KNHI 4A3MD 4PS4A 1WCMD 5IP9D 1BUYA 1RHGA 2B8ZA 4NN7A 3VA2A 5D71A 1IL6A 3QAZA 2CYKA 1ILKA 4NEJA 4ZS7A 4A3ED 4BY7D 4RS1A 3BPLA 1LQSL 3UF2A 1RFBA 2XQBA 5D72A 5D28B 3HHRA 1PW6A 3UF5A 1LK3A 1RW5A 3NCBA 3HOYD 3G6DA 3HOXD 2B8UA 3LB6B 1Y6NL 4A3ID 1AXIA 4DKCA 3D87A 3QT2C 2Q7NB 1HWGA 1BGDA 5D22A 2B63D 3HOWD 3SE3B 4X51A 3DGCL 1BCNA 1HIJA 3FKID 2B5IA 1IARA 1Z92A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C4X D;  5IP7 D;  5IYB D;  5IYC D;  5C44 D;  4A3G D;  3I4M D;  3PO2 D;  3H3V E;  2R7Z D;  2R93 D;  4A3J D;  4A3M D;  1WCM D;  5IP9 D;  3I4N D;  3AYH A;  4A3L D;  4A3E D;  2R92 D;  5C3E D;  2JA6 D;  5FLM D;  4BY7 D;  4BXX D;  3HOU D;  5IYD D;  2JA8 D;  3H0G D;  4A3F D;  4A93 D;  4BBS D;  4A3K D;  3HOY D;  4A3D D;  1Y1V D;  3HOX D;  2JA7 D;  3HOV D;  4A3I D;  1Y1W D;  4A3B D;  2JA5 D;  3HOW D;  2VUM D;  3HOZ D;  2B63 D;  2C35 A;  1Y14 A;  4BY1 D;  4BBR D;  4A3C D;  3FKI D;  3PO3 D; 
#chains in the Genus database with same CATH topology
 4IKV A;  1CD9 A;  1IRL A;  4GBY A;  5D59 A;  1INR A;  3NPZ A;  2LAG A;  1JLI A;  4W6V A;  5C7X A;  1IJZ A;  1M4A A;  1BGE A;  1PY2 A;  2GMF A;  1D9G A;  3PO3 D;  2Q14 A;  1ITI A;  1PV7 A;  3LB6 A;  3DI3 A;  4XNI A;  5L6Y C;  3D48 P;  3AYH A;  1M48 A;  2B8X A;  3DI2 A;  1AX8 A;  1B5L A;  4UVM A;  4O6K A;  1LKI A;  1CSG A;  1Y1W D;  1GNC A;  1CNT 1;  2O26 A;  1FG9 A;  4XNJ A;  4CNI C;  4IKW A;  4D2C A;  3UEZ E;  1RCB A;  4TPG A;  4PYP A;  3BPO A;  4U4W A;  2B8Y A;  2VUM D;  4ZF7 A;  5IYB D;  4YDY I;  4OAA A;  4BBR D;  1M47 A;  5IP9 D;  4NN7 A;  4ZS7 A;  3BPL A;  2XQB A;  3HOY D;  4LEP A;  2XUT A;  4A3I D;  1AXI A;  4DKC A;  5D22 A;  3DGC L;  1BGD A;  1HIJ A;  2B5I A;  5D6K A;  1ALU A;  5A2N A;  1ETE A;  2O27 A;  2D48 A;  1HWH A;  3D85 C;  3DUH C;  1I1R B;  4NI9 A;  4IKX A;  1IK0 A;  1EER A;  2LMS A;  3OG6 A;  4A3B D;  1EKU A;  2JA5 D;  4BY1 D;  2KZ1 A;  1Y14 A;  4DKD A;  1ITM A;  3MZG A;  3H3V E;  5EQG A;  4U4T A;  2Z3Q A;  4DKF A;  4NI7 A;  1FYH A;  1AU1 A;  4NN5 A;  3NCC A;  2C35 A;  3HMX B;  4A3C D;  1V7N V;  2L3Y A;  3QWR B;  5D70 A;  3SE4 B;  2OQP A;  1HGU A;  3I4N D;  2D9Q A;  3HOU D;  1HZI A;  4WRL B;  4U4V A;  3H0G D;  4A3K D;  4A3D D;  1Y1V D;  4IKZ A;  3OQ3 A;  4YUE C;  1CYL A;  4ZYR A;  1EVS A;  1WU3 I;  2V8N A;  3G9V B;  1BP3 A;  4YBQ A;  3PO2 D;  3OG4 A;  1HUL A;  3WCY I;  4A3M D;  1WCM D;  4LDS A;  1BUY A;  1RHG A;  5D71 A;  4NEJ A;  3UF2 A;  1RFB A;  5D72 A;  4Q65 A;  1Y6N L;  1HWG A;  3SE3 B;  3FKI D;  5C4X D;  1F6F A;  1D9C A;  1EXZ A;  2ERJ D;  1Y6M L;  4NEM A;  4NN6 A;  1EMR A;  4FA8 E;  5E4E A;  3EW3 A;  2R92 D;  5C3E D;  2JA6 D;  4A3F D;  4GRW A;  3PIW A;  1VLK A;  1BBN A;  2CFP A;  1ITF A;  1V7M V;  3QB7 A;  2E9W C;  2Q98 A;  2ILK A;  1M4B A;  4OH3 A;  5EQI A;  2R93 D;  2O6I A;  1F45 B;  5FHX A;  5FLM D;  3TGX B;  4D2B A;  1PW4 A;  3QB1 A;  1M49 A;  3BES L;  5GXB A;  4IKY A;  4GBZ A;  4GS7 A;  1KF9 A;  4DOH A;  4A3L D;  3L5X A;  3N0P A;  3DLQ I;  1BGC A;  1SCF A;  4BBS D;  5D58 A;  3B5K A;  1PV6 A;  4TPJ A;  1HUW A;  4LRL A;  3BPN A;  4ZWC A;  4ZWB A;  4EXN A;  2R7Z D;  3O7Q A;  3VA2 A;  4JA3 A;  4A3E D;  4BY7 D;  3UF5 A;  5D28 B;  1PW6 A;  1LK3 A;  2B8U A;  3LB6 B;  4IU8 A;  3D87 A;  3QT2 C;  2B63 D;  1BCN A;  2INT A;  1IAR A;  3L5W I;  5EQH A;  4TPH A;  3I4M D;  2H24 A;  4J4L C;  4DKE A;  1A22 A;  1QVN A;  5TS9 A;  3UX9 A;  1A7M A;  2CFQ A;  3HOV D;  3WDO A;  4YQX A;  1P9M B;  2L3O A;  4A3G D;  3NCF A;  1ITL A;  5C65 A;  1M4R A;  5IYC D;  4QIQ A;  3N06 A;  4MHL A;  3PIV A;  1HIK A;  4A3J D;  5A2O A;  4YPG C;  5IYD D;  5LQB A;  4JR9 A;  4A93 D;  1CN4 C;  2Z3R A;  1M4C A;  4APS A;  4J05 A;  2IL6 A;  1PVH B;  1GA3 A;  1NBP A;  4I77 Z;  5C44 D;  3IRH A;  1PGR A;  1Y6K L;  4JRE A;  3EJJ A;  4YB9 D;  4NKQ C;  1Z7C A;  4O9H A;  3O7P A;  5FUC A;  2JA8 D;  4GC0 A;  1J7V L;  2JA7 D;  2PSM A;  4Z5R D;  3NCE A;  2B91 A;  3HOZ D;  3INK C;  1YKB A;  5IP7 D;  1N1F A;  4EXP A;  3S9D A;  2HYM B;  2B90 A;  3Q1S I;  5KNH I;  4PS4 A;  2B8Z A;  1IL6 A;  3QAZ A;  4IU9 A;  2CYK A;  1ILK A;  4BXX D;  4RS1 A;  1LQS L;  3HHR A;  1RW5 A;  3NCB A;  2Y5Y A;  3G6D A;  3HOX D;  4ZW9 A;  2Q7N B;  3HOW D;  4D2D A;  4X51 A;  3HHC A;  1Z92 A; 
#chains in the Genus database with same CATH homology
 5C4X D;  1ALU A;  1F6F A;  1D9C A;  1CD9 A;  1ETE A;  2O27 A;  3L5W I;  1IRL A;  3I4M D;  1EXZ A;  2H24 A;  2D48 A;  1HWH A;  4J4L C;  1INR A;  3D85 C;  4DKE A;  3DUH C;  1A22 A;  3NPZ A;  2ERJ D;  1Y6M L;  1I1R B;  4NEM A;  4NN6 A;  4NI9 A;  1EMR A;  4FA8 E;  5E4E A;  2LAG A;  1QVN A;  3EW3 A;  5C3E D;  2JA6 D;  2R92 D;  1JLI A;  5TS9 A;  3UX9 A;  5C7X A;  4GRW A;  4A3F D;  3PIW A;  1A7M A;  1IJZ A;  1M4A A;  1IK0 A;  1EER A;  1VLK A;  1BGE A;  2LMS A;  3HOV D;  1BBN A;  1ITF A;  3OG6 A;  1PY2 A;  1V7M V;  2GMF A;  3QB7 A;  4YQX A;  1P9M B;  4A3B D;  1D9G A;  1EKU A;  2JA5 D;  2L3O A;  2E9W C;  2Q98 A;  4BY1 D;  4A3G D;  2KZ1 A;  1Y14 A;  3PO3 D;  2ILK A;  3NCF A;  1ITL A;  5IYC D;  1M4R A;  2Q14 A;  4DKD A;  1M4B A;  1ITI A;  3N06 A;  1ITM A;  3LB6 A;  4MHL A;  3MZG A;  3DI3 A;  3PIV A;  1HIK A;  5L6Y C;  3H3V E;  4A3J D;  2R93 D;  3D48 P;  2O6I A;  1F45 B;  1M48 A;  2B8X A;  3AYH A;  5FHX A;  3DI2 A;  5FLM D;  4YPG C;  3TGX B;  1AX8 A;  5IYD D;  1B5L A;  5LQB A;  4A93 D;  1CN4 C;  4O6K A;  2Z3R A;  1LKI A;  1M4C A;  2Z3Q A;  3HHC A;  4NI7 A;  4DKF A;  1CSG A;  1FYH A;  1AU1 A;  1Y1W D;  1GNC A;  3QB1 A;  4NN5 A;  1M49 A;  3NCC A;  1CNT 1;  2C35 A;  2IL6 A;  2O26 A;  3HMX B;  4A3C D;  3BES L;  1PVH B;  1GA3 A;  1NBP A;  1V7N V;  4I77 Z;  2L3Y A;  3QWR B;  5C44 D;  3IRH A;  1FG9 A;  1PGR A;  1Y6K L;  5D70 A;  4CNI C;  3EJJ A;  3SE4 B;  2OQP A;  1HGU A;  4GS7 A;  4NKQ C;  1Z7C A;  4BXX D;  3I4N D;  1KF9 A;  4DOH A;  4O9H A;  3UEZ E;  4A3L D;  3L5X A;  3N0P A;  5FUC A;  3DLQ I;  1BGC A;  2D9Q A;  3HOU D;  1HZI A;  1SCF A;  1RCB A;  4WRL B;  2JA8 D;  3H0G D;  1J7V L;  4BBS D;  4A3K D;  4A3D D;  1Y1V D;  2JA7 D;  3BPO A;  2PSM A;  3OQ3 A;  4YUE C;  1CYL A;  4Z5R D;  1EVS A;  1WU3 I;  2B91 A;  3NCE A;  2B8Y A;  3B5K A;  3G9V B;  3HOZ D;  2VUM D;  1HUW A;  4LRL A;  4ZF7 A;  3INK C;  1YKB A;  5IP7 D;  1N1F A;  1BP3 A;  5IYB D;  2INT A;  4EXP A;  3S9D A;  4YDY I;  3BPN A;  2HYM B;  2B90 A;  4EXN A;  4BBR D;  3PO2 D;  3OG4 A;  1M47 A;  2R7Z D;  1HUL A;  3Q1S I;  3WCY I;  5KNH I;  4A3M D;  4PS4 A;  1WCM D;  5IP9 D;  1BUY A;  1RHG A;  2B8Z A;  4NN7 A;  3VA2 A;  5D71 A;  1IL6 A;  3QAZ A;  2CYK A;  1ILK A;  4NEJ A;  4ZS7 A;  4A3E D;  4BY7 D;  4RS1 A;  3BPL A;  1LQS L;  3UF2 A;  1RFB A;  2XQB A;  5D72 A;  5D28 B;  3HHR A;  1PW6 A;  3UF5 A;  1LK3 A;  1RW5 A;  3NCB A;  3HOY D;  3G6D A;  3HOX D;  2B8U A;  3LB6 B;  1Y6N L;  4A3I D;  1AXI A;  4DKC A;  3D87 A;  3QT2 C;  2Q7N B;  1HWG A;  1BGD A;  5D22 A;  2B63 D;  3HOW D;  3SE3 B;  4X51 A;  3DGC L;  1BCN A;  1HIJ A;  3FKI D;  2B5I A;  1IAR A;  1Z92 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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