2JA8D

Cpd lesion containing rna polymerase ii elongation complex d
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
218
structure length
177
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cpd Damage Recognition by Transcribing RNA Polymerase II.
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 40
structure length 177
sequence length 218
ec nomenclature
pdb deposition date 2006-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 2ja8D02
5IP7D 5IYCD 5IYBD 2JA8D 4A3ID 4A3MD 5IYDD 2R7ZD 3AYHA 5IP9D 5C3ED 2JA7D 4A3GD 4BXXD 3HOWD 3H0GD 5FLMD 4A3DD 2JA6D 4A3JD 3FKID 4A3BD 2VUMD 3I4ND 3PO3D 2R93D 4BBSD 3H3VE 3HOZD 4BY7D 3HOVD 4A3LD 4A3ED 1Y1WD 4BY1D 5C4XD 3PO2D 1Y1VD 4A3FD 3HOYD 4A93D 3HOXD 2R92D 2C35A 2B63D 1Y14A 3I4MD 4BBRD 4A3CD 2JA5D 1WCMD 5C44D 4A3KD 3HOUD
chains in the Genus database with same CATH superfamily
2H24A 1GNCA 5C3ED 1QVNA 4ZYRA 4NKQC 3BPLA 2JA6D 5E4EA 5C65A 4XNJA 4QIQA 4UVMA 4J05A 3PO3D 4ZS7A 5D22A 1Y6NL 4YQXA 4ZW9A 3UF5A 1D9CA 2HYMB 2PSMA 4ZF7A 1PW4A 4PYPA 2B91A 4FA8E 3FKID 4IU9A 4A3BD 3H3VE 1BGEA 5C4XD 4DKCA 1ETEA 3D48P 1BGDA 2B8XA 1HZIA 2O26A 1A7MA 4DOHA 4LDSA 2B8UA 3HOUD 1INRA 1ITIA 1Z7CA 3B5KA 5KNHI 3INKC 2B8ZA 1LK3A 4NEJA 4O9HA 4A3LD 5D72A 1CN4C 1M4RA 1EKUA 2INTA 4A3KD 5IYCD 5IYDD 4EXPA 3EW3A 4WRLB 4Q65A 3OG4A 3QT2C 5FLMD 3NCCA 1ITMA 4O6KA 3UX9A 1EERA 4OAAA 1RFBA 3HOZD 1Y1WD 5FHXA 3VA2A 4YPGC 5D59A 4A3FD 4YDYI 4JREA 1BP3A 3UEZE 5A2OA 4A3CD 2V8NA 4RS1A 2KZ1A 4BXXD 2D9QA 4LEPA 3NCBA 1NBPA 3HMXB 4U4TA 3HOXD 1PGRA 1BUYA 4CNIC 2R7ZD 4ZWBA 2GMFA 1P9MB 4IKVA 1CSGA 2R93D 3QB7A 2B5IA 3L5XA 4BY1D 3DGCL 4IKWA 2CFPA 4MHLA 5D58A 3N0PA 1FYHA 3IRHA 2B90A 3DUHC 3EJJA 2O6IA 3BESL 1IJZA 3HOWD 4X51A 4A3DD 3QAZA 5A2NA 4LRLA 2LMSA 3NCFA 3HHRA 4D2CA 3DI3A 1PVHB 3OG6A 3HOYD 4NN7A 1RW5A 4YB9D 4NEMA 2Z3QA 4J4LC 1Y6KL 1SCFA 4TPHA 1LKIA 1AU1A 1M47A 4U4VA 3QB1A 1FG9A 4D2DA 1IRLA 2CYKA 1Y1VD 5TS9A 3O7PA 1V7NV 1M49A 4GS7A 4NI7A 5L6YC 2IL6A 4NI9A 4YBQA 3G9VB 1M48A 3PIWA 1M4BA 4APSA 2JA8D 4IKYA 4A3GD 1PV7A 4GBYA 4DKFA 4A3ED 1B5LA 1BCNA 1BGCA 4TPGA 5EQIA 1Y14A 2B8YA 1CD9A 3I4MD 4BBRD 2JA5D 2ERJD 4IU8A 4I77Z 1HULA 4D2BA 2XUTA 3H0GD 4NN6A 1HWGA 3MZGA 2Q14A 4BY7D 4GC0A 1M4AA 1YKBA 1CYLA 3PO2D 2ILKA 2XQBA 5EQHA 2Q98A 1EVSA 1LQSL 1PW6A 3UF2A 2O27A 4IKXA 1RCBA 4Z5RD 1HIKA 3WDOA 3WCYI 1IL6A 4XNIA 4GRWA 1GA3A 3SE4B 3D85C 4JR9A 3I4ND 4BBSD 4DKDA 1ITFA 4GBZA 5C44D 3S9DA 4TPJA 5D71A 1V7MV 1WU3I 5IP9D 1HGUA 1I1RB 2LAGA 4PS4A 4U4WA 1CNT1 5EQGA 2E9WC 4OH3A 4A3MD 3NPZA 2Y5YA 1AXIA 1D9GA 1AX8A 1ITLA 3NCEA 5D6KA 2VUMD 2L3OA 1RHGA 1EXZA 2Z3RA 3Q1SI 1IARA 4JA3A 4YUEC 1ALUA 3PIVA 5IP7D 3HHCA 3BPOA 1KF9A 5C7XA 1J7VL 2D48A 1HIJA 1VLKA 3DI2A 2B63D 3SE3B 1HUWA 4EXNA 1HWHA 4W6VA 3D87A 5IYBD 5FUCA 1A22A 4DKEA 5LQBA 1BBNA 1Z92A 3N06A 3LB6B 1N1FA 3LB6A 3HOVD 1F6FA 1PY2A 2OQPA 5GXBA 3O7QA 4NN5A 4A93D 3TGXB 5D28B 2R92D 2C35A 1WCMD 3L5WI 1ILKA 2CFQA 4A3ID 3AYHA 1M4CA 2JA7D 3QWRB 3G6DA 4IKZA 1Y6ML 4A3JD 2Q7NB 3OQ3A 1F45B 4ZWCA 1PV6A 3BPNA 2L3YA 5D70A 1IK0A 3DLQI 1EMRA 1JLIA
chains in the Genus database with same CATH topology
4RS1A 1M4BA 2H24A 2JA8D 4A3MD 3NPZA 1GNCA 5C3ED 1QVNA 2KZ1A 1AXIA 4A3GD 4BXXD 3HOWD 4NKQC 2D9QA 1D9GA 1AX8A 3NCBA 3BPLA 2JA6D 5E4EA 1ITLA 3NCEA 2VUMD 1NBPA 2L3OA 3PO3D 4DKFA 1RHGA 1EXZA 2Z3RA 4ZS7A 5D22A 4A3ED 3Q1SI 1B5LA 1BCNA 1Y6NL 4YQXA 1BGCA 3HMXB 3HOXD 1PGRA 1Y14A 2B8YA 1CD9A 3I4MD 4BBRD 2JA5D 2ERJD 3UF5A 1BUYA 4I77Z 1HULA 4YUEC 1ALUA 3PIVA 1D9CA 5IP7D 4CNIC 3HHCA 3BPOA 2HYMB 2R7ZD 2PSMA 4ZF7A 2GMFA 3H0GD 1KF9A 1P9MB 2B91A 4NN6A 4FA8E 1HWGA 3FKID 3MZGA 5C7XA 1CSGA 4A3BD 2R93D 1J7VL 2Q14A 3QB7A 3H3VE 4BY7D 1M4AA 1YKBA 2B5IA 3L5XA 2D48A 4BY1D 1BGEA 5C4XD 1CYLA 4DKCA 3PO2D 2ILKA 1HIJA 1ETEA 1VLKA 3D48P 3DGCL 3DI2A 1BGDA 2B8XA 1HZIA 2XQBA 2B63D 3SE3B 2O26A 2Q98A 1EVSA 1A7MA 1LQSL 1HUWA 4DOHA 1PW6A 3UF2A 4MHLA 4EXNA 1HWHA 2O27A 3N0PA 2B8UA 3HOUD 1FYHA 1INRA 3IRHA 3D87A 5IYBD 2B90A 5FUCA 1A22A 1RCBA 3DUHC 4Z5RD 1ITIA 1Z7CA 3EJJA 4DKEA 2O6IA 3B5KA 3BESL 1IJZA 3INKC 1HIKA 5KNHI 5LQBA 1BBNA 2B8ZA 4X51A 1IL6A 3WCYI 4A3DD 1Z92A 3N06A 1LK3A 3QAZA 3LB6B 4GRWA 4NEJA 3SE4B 1GA3A 4LRLA 3D85C 3I4ND 1N1FA 2LMSA 3LB6A 3NCFA 4BBSD 4O9HA 3HHRA 3HOVD 4A3LD 3DI3A 1F6FA 1PY2A 4DKDA 2OQPA 1ITFA 1JLIA 1PVHB 4NN5A 3OG6A 3HOYD 4A93D 3TGXB 5D28B 2R92D 2C35A 5D72A 4NN7A 1CN4C 1M4RA 1RW5A 1EKUA 1WCMD 5C44D 2INTA 3L5WI 3S9DA 4NEMA 4A3KD 2Z3QA 1ILKA 5IYCD 5D71A 4J4LC 4A3ID 1V7MV 1WU3I 5IYDD 3AYHA 1M4CA 1Y6KL 4EXPA 3EW3A 4WRLB 5IP9D 2JA7D 3OG4A 3QT2C 5FLMD 3NCCA 3QWRB 1SCFA 3G6DA 1ITMA 1Y6ML 1HGUA 1LKIA 4A3JD 2Q7NB 1I1RB 3OQ3A 2LAGA 1F45B 4O6KA 3UX9A 1AU1A 1EERA 1M47A 4PS4A 3QB1A 1FG9A 1RFBA 3HOZD 3BPNA 1IRLA 1Y1WD 5FHXA 3VA2A 4YPGC 2L3YA 5D70A 1IK0A 2CYKA 1Y1VD 4A3FD 3DLQI 5TS9A 1CNT1 1V7NV 1BP3A 4YDYI 1M49A 1EMRA 4GS7A 4NI7A 3UEZE 2IL6A 5L6YC 4NI9A 2E9WC 4A3CD 3G9VB 1IARA 1M48A 3PIWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IP7 D;  5IYC D;  5IYB D;  2JA8 D;  4A3I D;  4A3M D;  5IYD D;  2R7Z D;  3AYH A;  5IP9 D;  5C3E D;  2JA7 D;  4A3G D;  4BXX D;  3HOW D;  3H0G D;  5FLM D;  4A3D D;  2JA6 D;  4A3J D;  3FKI D;  4A3B D;  2VUM D;  3I4N D;  3PO3 D;  2R93 D;  4BBS D;  3H3V E;  3HOZ D;  4BY7 D;  3HOV D;  4A3L D;  4A3E D;  1Y1W D;  4BY1 D;  5C4X D;  3PO2 D;  1Y1V D;  4A3F D;  3HOY D;  4A93 D;  3HOX D;  2R92 D;  2C35 A;  2B63 D;  1Y14 A;  3I4M D;  4BBR D;  4A3C D;  2JA5 D;  1WCM D;  5C44 D;  4A3K D;  3HOU D; 
#chains in the Genus database with same CATH topology
 2H24 A;  1GNC A;  5C3E D;  1QVN A;  4ZYR A;  4NKQ C;  3BPL A;  2JA6 D;  5E4E A;  5C65 A;  4XNJ A;  4QIQ A;  4UVM A;  4J05 A;  3PO3 D;  4ZS7 A;  5D22 A;  1Y6N L;  4YQX A;  4ZW9 A;  3UF5 A;  1D9C A;  2HYM B;  2PSM A;  4ZF7 A;  1PW4 A;  4PYP A;  2B91 A;  4FA8 E;  3FKI D;  4IU9 A;  4A3B D;  3H3V E;  1BGE A;  5C4X D;  4DKC A;  1ETE A;  3D48 P;  1BGD A;  2B8X A;  1HZI A;  2O26 A;  1A7M A;  4DOH A;  4LDS A;  2B8U A;  3HOU D;  1INR A;  1ITI A;  1Z7C A;  3B5K A;  5KNH I;  3INK C;  2B8Z A;  1LK3 A;  4NEJ A;  4O9H A;  4A3L D;  5D72 A;  1CN4 C;  1M4R A;  1EKU A;  2INT A;  4A3K D;  5IYC D;  5IYD D;  4EXP A;  3EW3 A;  4WRL B;  4Q65 A;  3OG4 A;  3QT2 C;  5FLM D;  3NCC A;  1ITM A;  4O6K A;  3UX9 A;  1EER A;  4OAA A;  1RFB A;  3HOZ D;  1Y1W D;  5FHX A;  3VA2 A;  4YPG C;  5D59 A;  4A3F D;  4YDY I;  4JRE A;  1BP3 A;  3UEZ E;  5A2O A;  4A3C D;  2V8N A;  4RS1 A;  2KZ1 A;  4BXX D;  2D9Q A;  4LEP A;  3NCB A;  1NBP A;  3HMX B;  4U4T A;  3HOX D;  1PGR A;  1BUY A;  4CNI C;  2R7Z D;  4ZWB A;  2GMF A;  1P9M B;  4IKV A;  1CSG A;  2R93 D;  3QB7 A;  2B5I A;  3L5X A;  4BY1 D;  3DGC L;  4IKW A;  2CFP A;  4MHL A;  5D58 A;  3N0P A;  1FYH A;  3IRH A;  2B90 A;  3DUH C;  3EJJ A;  2O6I A;  3BES L;  1IJZ A;  3HOW D;  4X51 A;  4A3D D;  3QAZ A;  5A2N A;  4LRL A;  2LMS A;  3NCF A;  3HHR A;  4D2C A;  3DI3 A;  1PVH B;  3OG6 A;  3HOY D;  4NN7 A;  1RW5 A;  4YB9 D;  4NEM A;  2Z3Q A;  4J4L C;  1Y6K L;  1SCF A;  4TPH A;  1LKI A;  1AU1 A;  1M47 A;  4U4V A;  3QB1 A;  1FG9 A;  4D2D A;  1IRL A;  2CYK A;  1Y1V D;  5TS9 A;  3O7P A;  1V7N V;  1M49 A;  4GS7 A;  4NI7 A;  5L6Y C;  2IL6 A;  4NI9 A;  4YBQ A;  3G9V B;  1M48 A;  3PIW A;  1M4B A;  4APS A;  2JA8 D;  4IKY A;  4A3G D;  1PV7 A;  4GBY A;  4DKF A;  4A3E D;  1B5L A;  1BCN A;  1BGC A;  4TPG A;  5EQI A;  1Y14 A;  2B8Y A;  1CD9 A;  3I4M D;  4BBR D;  2JA5 D;  2ERJ D;  4IU8 A;  4I77 Z;  1HUL A;  4D2B A;  2XUT A;  3H0G D;  4NN6 A;  1HWG A;  3MZG A;  2Q14 A;  4BY7 D;  4GC0 A;  1M4A A;  1YKB A;  1CYL A;  3PO2 D;  2ILK A;  2XQB A;  5EQH A;  2Q98 A;  1EVS A;  1LQS L;  1PW6 A;  3UF2 A;  2O27 A;  4IKX A;  1RCB A;  4Z5R D;  1HIK A;  3WDO A;  3WCY I;  1IL6 A;  4XNI A;  4GRW A;  1GA3 A;  3SE4 B;  3D85 C;  4JR9 A;  3I4N D;  4BBS D;  4DKD A;  1ITF A;  4GBZ A;  5C44 D;  3S9D A;  4TPJ A;  5D71 A;  1V7M V;  1WU3 I;  5IP9 D;  1HGU A;  1I1R B;  2LAG A;  4PS4 A;  4U4W A;  1CNT 1;  5EQG A;  2E9W C;  4OH3 A;  4A3M D;  3NPZ A;  2Y5Y A;  1AXI A;  1D9G A;  1AX8 A;  1ITL A;  3NCE A;  5D6K A;  2VUM D;  2L3O A;  1RHG A;  1EXZ A;  2Z3R A;  3Q1S I;  1IAR A;  4JA3 A;  4YUE C;  1ALU A;  3PIV A;  5IP7 D;  3HHC A;  3BPO A;  1KF9 A;  5C7X A;  1J7V L;  2D48 A;  1HIJ A;  1VLK A;  3DI2 A;  2B63 D;  3SE3 B;  1HUW A;  4EXN A;  1HWH A;  4W6V A;  3D87 A;  5IYB D;  5FUC A;  1A22 A;  4DKE A;  5LQB A;  1BBN A;  1Z92 A;  3N06 A;  3LB6 B;  1N1F A;  3LB6 A;  3HOV D;  1F6F A;  1PY2 A;  2OQP A;  5GXB A;  3O7Q A;  4NN5 A;  4A93 D;  3TGX B;  5D28 B;  2R92 D;  2C35 A;  1WCM D;  3L5W I;  1ILK A;  2CFQ A;  4A3I D;  3AYH A;  1M4C A;  2JA7 D;  3QWR B;  3G6D A;  4IKZ A;  1Y6M L;  4A3J D;  2Q7N B;  3OQ3 A;  1F45 B;  4ZWC A;  1PV6 A;  3BPN A;  2L3Y A;  5D70 A;  1IK0 A;  3DLQ I;  1EMR A;  1JLI A; 
#chains in the Genus database with same CATH homology
 4RS1 A;  1M4B A;  2H24 A;  2JA8 D;  4A3M D;  3NPZ A;  1GNC A;  5C3E D;  1QVN A;  2KZ1 A;  1AXI A;  4A3G D;  4BXX D;  3HOW D;  4NKQ C;  2D9Q A;  1D9G A;  1AX8 A;  3NCB A;  3BPL A;  2JA6 D;  5E4E A;  1ITL A;  3NCE A;  2VUM D;  1NBP A;  2L3O A;  3PO3 D;  4DKF A;  1RHG A;  1EXZ A;  2Z3R A;  4ZS7 A;  5D22 A;  4A3E D;  3Q1S I;  1B5L A;  1BCN A;  1Y6N L;  4YQX A;  1BGC A;  3HMX B;  3HOX D;  1PGR A;  1Y14 A;  2B8Y A;  1CD9 A;  3I4M D;  4BBR D;  2JA5 D;  2ERJ D;  3UF5 A;  1BUY A;  4I77 Z;  1HUL A;  4YUE C;  1ALU A;  3PIV A;  1D9C A;  5IP7 D;  4CNI C;  3HHC A;  3BPO A;  2HYM B;  2R7Z D;  2PSM A;  4ZF7 A;  2GMF A;  3H0G D;  1KF9 A;  1P9M B;  2B91 A;  4NN6 A;  4FA8 E;  1HWG A;  3FKI D;  3MZG A;  5C7X A;  1CSG A;  4A3B D;  2R93 D;  1J7V L;  2Q14 A;  3QB7 A;  3H3V E;  4BY7 D;  1M4A A;  1YKB A;  2B5I A;  3L5X A;  2D48 A;  4BY1 D;  1BGE A;  5C4X D;  1CYL A;  4DKC A;  3PO2 D;  2ILK A;  1HIJ A;  1ETE A;  1VLK A;  3D48 P;  3DGC L;  3DI2 A;  1BGD A;  2B8X A;  1HZI A;  2XQB A;  2B63 D;  3SE3 B;  2O26 A;  2Q98 A;  1EVS A;  1A7M A;  1LQS L;  1HUW A;  4DOH A;  1PW6 A;  3UF2 A;  4MHL A;  4EXN A;  1HWH A;  2O27 A;  3N0P A;  2B8U A;  3HOU D;  1FYH A;  1INR A;  3IRH A;  3D87 A;  5IYB D;  2B90 A;  5FUC A;  1A22 A;  1RCB A;  3DUH C;  4Z5R D;  1ITI A;  1Z7C A;  3EJJ A;  4DKE A;  2O6I A;  3B5K A;  3BES L;  1IJZ A;  3INK C;  1HIK A;  5KNH I;  5LQB A;  1BBN A;  2B8Z A;  4X51 A;  1IL6 A;  3WCY I;  4A3D D;  1Z92 A;  3N06 A;  1LK3 A;  3QAZ A;  3LB6 B;  4GRW A;  4NEJ A;  3SE4 B;  1GA3 A;  4LRL A;  3D85 C;  3I4N D;  1N1F A;  2LMS A;  3LB6 A;  3NCF A;  4BBS D;  4O9H A;  3HHR A;  3HOV D;  4A3L D;  3DI3 A;  1F6F A;  1PY2 A;  4DKD A;  2OQP A;  1ITF A;  1JLI A;  1PVH B;  4NN5 A;  3OG6 A;  3HOY D;  4A93 D;  3TGX B;  5D28 B;  2R92 D;  2C35 A;  5D72 A;  4NN7 A;  1CN4 C;  1M4R A;  1RW5 A;  1EKU A;  1WCM D;  5C44 D;  2INT A;  3L5W I;  3S9D A;  4NEM A;  4A3K D;  2Z3Q A;  1ILK A;  5IYC D;  5D71 A;  4J4L C;  4A3I D;  1V7M V;  1WU3 I;  5IYD D;  3AYH A;  1M4C A;  1Y6K L;  4EXP A;  3EW3 A;  4WRL B;  5IP9 D;  2JA7 D;  3OG4 A;  3QT2 C;  5FLM D;  3NCC A;  3QWR B;  1SCF A;  3G6D A;  1ITM A;  1Y6M L;  1HGU A;  1LKI A;  4A3J D;  2Q7N B;  1I1R B;  3OQ3 A;  2LAG A;  1F45 B;  4O6K A;  3UX9 A;  1AU1 A;  1EER A;  1M47 A;  4PS4 A;  3QB1 A;  1FG9 A;  1RFB A;  3HOZ D;  3BPN A;  1IRL A;  1Y1W D;  5FHX A;  3VA2 A;  4YPG C;  2L3Y A;  5D70 A;  1IK0 A;  2CYK A;  1Y1V D;  4A3F D;  3DLQ I;  5TS9 A;  1CNT 1;  1V7N V;  1BP3 A;  4YDY I;  1M49 A;  1EMR A;  4GS7 A;  4NI7 A;  3UEZ E;  2IL6 A;  5L6Y C;  4NI9 A;  2E9W C;  4A3C D;  3G9V B;  1IAR A;  1M48 A;  3PIW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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