2R92D

Elongation complex of rna polymerase ii with artificial rdrp scaffold
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
219
structure length
178
Chain Sequence
b'VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords RNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3
publication title Molecular basis of RNA-dependent RNA polymerase II activity.
pubmed doi rcsb
molecule tags Transferase/rna
total genus 44
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 2r92D02
3HOWD 4A3JD 2VUMD 3HOXD 5FLMD 2R7ZD 4A3BD 5IYCD 4A3KD 3H3VE 4BXXD 4BY1D 1WCMD 4A3LD 3PO3D 3AYHA 4A3ED 1Y1VD 5C4XD 3I4ND 3I4MD 4A93D 3PO2D 4BY7D 2R92D 3HOYD 2JA5D 4A3CD 1Y14A 3HOUD 3FKID 2B63D 3H0GD 2C35A 5IP9D 1Y1WD 4A3GD 4A3FD 4BBSD 4A3MD 4BBRD 5IYDD 5C44D 2JA6D 3HOZD 2R93D 4A3ID 2JA7D 5IP7D 5C3ED 5IYBD 3HOVD 4A3DD 2JA8D
chains in the Genus database with same CATH superfamily
3HOWD 2ILKA 2HYMB 3OQ3A 1A7MA 4BXXD 4IKZA 3QT2C 5GXBA 2LMSA 1BGDA 1P9MB 3DLQI 3G9VB 2Z3QA 5E4EA 3HMXB 1CYLA 3HHRA 1F45B 1PW6A 4NEJA 4BBSD 5C44D 1CN4C 2JA7D 2O27A 1ITIA 1EVSA 5D59A 1HULA 4TPJA 3Q1SI 1HIJA 3O7QA 3SE4B 3S9DA 3PO3D 3DI3A 2OQPA 3EW3A 4O9HA 1ALUA 1LKIA 3FKID 4IU9A 1GA3A 3NCFA 1BP3A 3HOVD 3WCYI 1IARA 5FLMD 3UX9A 1BGCA 1QVNA 3NCEA 1V7MV 3I4ND 2IL6A 1BCNA 2B8YA 4NKQC 3BPNA 1Y1WD 4A3FD 1KF9A 1ITLA 4O6KA 5C3ED 2Q98A 4TPHA 1YKBA 1IJZA 1CNT1 4IKYA 1HIKA 5EQIA 4OAAA 1PW4A 5C65A 5D28B 1M47A 1PV7A 4YDYI 4GC0A 4QIQA 2JA6D 5KNHI 2LAGA 4ZF7A 4A3JD 1V7NV 5IYCD 1Y6KL 1HUWA 3L5WI 1IL6A 4A3CD 5D6KA 1AXIA 1HGUA 3PIWA 4LDSA 4PYPA 4NEMA 4CNIC 3H3VE 1ITFA 4FA8E 1WCMD 1B5LA 4YBQA 4MHLA 5EQGA 3QB1A 4D2BA 2C35A 3EJJA 3DGCL 4IKVA 1Z92A 4U4WA 1CD9A 1HWHA 2PSMA 3UF5A 3QWRB 5D71A 3QB7A 4X51A 3D85C 4LRLA 2Q7NB 1EKUA 2Q14A 4A93D 5L6YC 3OG4A 2R92D 3HOYD 1Y14A 2B63D 4W6VA 4YQXA 1JLIA 5IP9D 4A3MD 1D9GA 4D2CA 4NN5A 1ITMA 4ZWBA 1PY2A 3HHCA 4XNIA 4A3LD 3N06A 4JA3A 3UF2A 4IKXA 5FUCA 4NN7A 4ZWCA 2Y5YA 2R93D 1M49A 2GMFA 5IP7D 3BPLA 4EXPA 1J7VL 1D9CA 1LQSL 3HOXD 2XQBA 4U4VA 1IRLA 1EERA 4YPGC 1BUYA 4A3ED 2XUTA 2D48A 4J05A 5D70A 1SCFA 1EXZA 4D2DA 1CSGA 4GRWA 2KZ1A 2B8ZA 2B90A 4A3ID 4ZW9A 4JR9A 3L5XA 3NCCA 4PS4A 3PIVA 4A3DD 2CFQA 1Y6ML 4UVMA 3I4MD 5LQBA 2CFPA 5A2NA 1M4RA 1N1FA 1GNCA 3NPZA 3VA2A 2L3OA 4GS7A 3TGXB 3QAZA 2O6IA 2VUMD 5D72A 5D22A 2R7ZD 1Y6NL 1AX8A 4A3BD 4ZS7A 4RS1A 2B8XA 3AYHA 4JREA 2JA5D 4NN6A 1M48A 2O26A 4NI9A 4TPGA 1RHGA 3DUHC 2L3YA 2V8NA 1A22A 1PVHB 3INKC 4YUEC 4YB9D 2ERJD 1BBNA 3LB6A 4BY1D 4LEPA 5C4XD 1M4AA 5C7XA 3HOUD 3H0GD 3MZGA 4DKCA 3OG6A 1INRA 2INTA 4APSA 3N0PA 3HOZD 5FHXA 4DKDA 2B8UA 3BESL 1Z7CA 1BGEA 3SE3B 3UEZE 1ILKA 4U4TA 1Y1VD 4IKWA 1NBPA 4BY7D 3BPOA 1M4BA 4GBZA 4Q65A 4EXNA 3DI2A 1HZIA 3NCBA 4Z5RD 4OH3A 1RFBA 4DKFA 4DKEA 2E9WC 3D87A 1PV6A 1IK0A 1RW5A 4XNJA 1FYHA 4I77Z 2H24A 1F6FA 5A2OA 5IYBD 2JA8D 1EMRA 4WRLB 2CYKA 4J4LC 5TS9A 1I1RB 3D48P 3PO2D 2Z3RA 5EQHA 3WDOA 1ETEA 1LK3A 3IRHA 5D58A 4BBRD 5IYDD 3G6DA 1PGRA 3B5KA 4NI7A 2B5IA 3LB6B 1M4CA 1VLKA 1RCBA 4A3KD 3O7PA 2B91A 4DOHA 1FG9A 4GBYA 4ZYRA 4IU8A 2D9QA 4A3GD 1WU3I 1AU1A 1HWGA
chains in the Genus database with same CATH topology
1J7VL 4ZF7A 1D9CA 3HOWD 5FHXA 4A3JD 1V7NV 1LQSL 3HOXD 2ILKA 4DKDA 2HYMB 3OQ3A 5IYCD 2B8UA 2XQBA 3BESL 4BXXD 1A7MA 1Z7CA 1BGEA 3SE3B 3UEZE 1IRLA 1ILKA 3QT2C 1Y6KL 1EERA 4YPGC 2LMSA 1BUYA 1BGDA 1P9MB 4A3ED 1Y1VD 1HUWA 2D48A 2Z3QA 3DLQI 1NBPA 3G9VB 3L5WI 5D70A 1IL6A 3BPOA 2R7ZD 4BY7D 1SCFA 5E4EA 1M4BA 3HMXB 4A3CD 1EXZA 1AXIA 1HGUA 1CYLA 3HHRA 1F45B 3PIWA 1CSGA 4GRWA 4EXNA 3DI2A 1PW6A 2KZ1A 2B8ZA 2B90A 4NEMA 4NEJA 1CN4C 1HZIA 3NCBA 5C44D 4A3ID 2JA7D 4Z5RD 2O27A 1ITIA 3L5XA 3NCCA 4PS4A 3PIVA 4A3DD 1EVSA 1RFBA 4CNIC 4DKFA 1HULA 4DKEA 3H3VE 3Q1SI 2E9WC 3D87A 1ITFA 4FA8E 1Y6ML 1WCMD 1IK0A 1HIJA 3SE4B 3S9DA 3PO3D 3DI3A 1B5LA 2OQPA 3I4MD 5LQBA 4BBSD 1RW5A 3EW3A 1M4RA 1N1FA 4MHLA 4O9HA 1GNCA 1ALUA 1LKIA 3FKID 3QB1A 1FYHA 3NPZA 4I77Z 1GA3A 2C35A 3EJJA 3NCFA 3DGCL 2H24A 1F6FA 1BP3A 3VA2A 1Z92A 1CD9A 1HWHA 2PSMA 5IYBD 3HOVD 2L3OA 2JA8D 4GS7A 3TGXB 3QAZA 1EMRA 3WCYI 2O6IA 3UF5A 3QWRB 1IARA 4WRLB 2CYKA 5D72A 3QB7A 5D71A 5D22A 5FLMD 1Y6NL 1AX8A 4X51A 3D85C 1BGCA 4LRLA 3UX9A 4ZS7A 4A3BD 4RS1A 1QVNA 2Q7NB 4J4LC 2B8XA 1EKUA 2Q14A 5TS9A 3AYHA 3NCEA 1I1RB 1V7MV 3I4ND 4A93D 3D48P 3PO2D 5L6YC 3OG4A 2R92D 3HOYD 2Z3RA 2JA5D 1Y14A 2IL6A 4NN6A 1M48A 1ETEA 1LK3A 2B8YA 2O26A 4YQXA 2B63D 1JLIA 4NKQC 4NI9A 1BCNA 5IP9D 3BPNA 3IRHA 1Y1WD 4A3FD 1D9GA 4BBRD 1KF9A 3G6DA 1PGRA 1RHGA 3B5KA 4NN5A 5IYDD 4A3MD 1ITLA 1ITMA 4O6KA 4NI7A 2B5IA 5C3ED 2Q98A 2L3YA 1M4CA 3DUHC 3LB6B 1VLKA 1YKBA 1A22A 1RCBA 1PVHB 3INKC 4YUEC 1PY2A 4A3KD 2VUMD 1IJZA 3HHCA 1CNT1 2B91A 2ERJD 1BBNA 3LB6A 4BY1D 4A3LD 1HIKA 4DOHA 1FG9A 3N06A 5C4XD 3BPLA 1M4AA 5C7XA 5D28B 3HOUD 3UF2A 3H0GD 5FUCA 1M47A 3MZGA 4NN7A 4DKCA 3OG6A 4YDYI 1INRA 2INTA 2D9QA 4A3GD 1WU3I 3N0PA 2JA6D 3HOZD 2R93D 1M49A 1AU1A 2GMFA 5IP7D 5KNHI 2LAGA 4EXPA 1HWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOW D;  4A3J D;  2VUM D;  3HOX D;  5FLM D;  2R7Z D;  4A3B D;  5IYC D;  4A3K D;  3H3V E;  4BXX D;  4BY1 D;  1WCM D;  4A3L D;  3PO3 D;  3AYH A;  4A3E D;  1Y1V D;  5C4X D;  3I4N D;  3I4M D;  4A93 D;  3PO2 D;  4BY7 D;  2R92 D;  3HOY D;  2JA5 D;  4A3C D;  1Y14 A;  3HOU D;  3FKI D;  2B63 D;  3H0G D;  2C35 A;  5IP9 D;  1Y1W D;  4A3G D;  4A3F D;  4BBS D;  4A3M D;  4BBR D;  5IYD D;  5C44 D;  2JA6 D;  3HOZ D;  2R93 D;  4A3I D;  2JA7 D;  5IP7 D;  5C3E D;  5IYB D;  3HOV D;  4A3D D;  2JA8 D; 
#chains in the Genus database with same CATH topology
 3HOW D;  2ILK A;  2HYM B;  3OQ3 A;  1A7M A;  4BXX D;  4IKZ A;  3QT2 C;  5GXB A;  2LMS A;  1BGD A;  1P9M B;  3DLQ I;  3G9V B;  2Z3Q A;  5E4E A;  3HMX B;  1CYL A;  3HHR A;  1F45 B;  1PW6 A;  4NEJ A;  4BBS D;  5C44 D;  1CN4 C;  2JA7 D;  2O27 A;  1ITI A;  1EVS A;  5D59 A;  1HUL A;  4TPJ A;  3Q1S I;  1HIJ A;  3O7Q A;  3SE4 B;  3S9D A;  3PO3 D;  3DI3 A;  2OQP A;  3EW3 A;  4O9H A;  1ALU A;  1LKI A;  3FKI D;  4IU9 A;  1GA3 A;  3NCF A;  1BP3 A;  3HOV D;  3WCY I;  1IAR A;  5FLM D;  3UX9 A;  1BGC A;  1QVN A;  3NCE A;  1V7M V;  3I4N D;  2IL6 A;  1BCN A;  2B8Y A;  4NKQ C;  3BPN A;  1Y1W D;  4A3F D;  1KF9 A;  1ITL A;  4O6K A;  5C3E D;  2Q98 A;  4TPH A;  1YKB A;  1IJZ A;  1CNT 1;  4IKY A;  1HIK A;  5EQI A;  4OAA A;  1PW4 A;  5C65 A;  5D28 B;  1M47 A;  1PV7 A;  4YDY I;  4GC0 A;  4QIQ A;  2JA6 D;  5KNH I;  2LAG A;  4ZF7 A;  4A3J D;  1V7N V;  5IYC D;  1Y6K L;  1HUW A;  3L5W I;  1IL6 A;  4A3C D;  5D6K A;  1AXI A;  1HGU A;  3PIW A;  4LDS A;  4PYP A;  4NEM A;  4CNI C;  3H3V E;  1ITF A;  4FA8 E;  1WCM D;  1B5L A;  4YBQ A;  4MHL A;  5EQG A;  3QB1 A;  4D2B A;  2C35 A;  3EJJ A;  3DGC L;  4IKV A;  1Z92 A;  4U4W A;  1CD9 A;  1HWH A;  2PSM A;  3UF5 A;  3QWR B;  5D71 A;  3QB7 A;  4X51 A;  3D85 C;  4LRL A;  2Q7N B;  1EKU A;  2Q14 A;  4A93 D;  5L6Y C;  3OG4 A;  2R92 D;  3HOY D;  1Y14 A;  2B63 D;  4W6V A;  4YQX A;  1JLI A;  5IP9 D;  4A3M D;  1D9G A;  4D2C A;  4NN5 A;  1ITM A;  4ZWB A;  1PY2 A;  3HHC A;  4XNI A;  4A3L D;  3N06 A;  4JA3 A;  3UF2 A;  4IKX A;  5FUC A;  4NN7 A;  4ZWC A;  2Y5Y A;  2R93 D;  1M49 A;  2GMF A;  5IP7 D;  3BPL A;  4EXP A;  1J7V L;  1D9C A;  1LQS L;  3HOX D;  2XQB A;  4U4V A;  1IRL A;  1EER A;  4YPG C;  1BUY A;  4A3E D;  2XUT A;  2D48 A;  4J05 A;  5D70 A;  1SCF A;  1EXZ A;  4D2D A;  1CSG A;  4GRW A;  2KZ1 A;  2B8Z A;  2B90 A;  4A3I D;  4ZW9 A;  4JR9 A;  3L5X A;  3NCC A;  4PS4 A;  3PIV A;  4A3D D;  2CFQ A;  1Y6M L;  4UVM A;  3I4M D;  5LQB A;  2CFP A;  5A2N A;  1M4R A;  1N1F A;  1GNC A;  3NPZ A;  3VA2 A;  2L3O A;  4GS7 A;  3TGX B;  3QAZ A;  2O6I A;  2VUM D;  5D72 A;  5D22 A;  2R7Z D;  1Y6N L;  1AX8 A;  4A3B D;  4ZS7 A;  4RS1 A;  2B8X A;  3AYH A;  4JRE A;  2JA5 D;  4NN6 A;  1M48 A;  2O26 A;  4NI9 A;  4TPG A;  1RHG A;  3DUH C;  2L3Y A;  2V8N A;  1A22 A;  1PVH B;  3INK C;  4YUE C;  4YB9 D;  2ERJ D;  1BBN A;  3LB6 A;  4BY1 D;  4LEP A;  5C4X D;  1M4A A;  5C7X A;  3HOU D;  3H0G D;  3MZG A;  4DKC A;  3OG6 A;  1INR A;  2INT A;  4APS A;  3N0P A;  3HOZ D;  5FHX A;  4DKD A;  2B8U A;  3BES L;  1Z7C A;  1BGE A;  3SE3 B;  3UEZ E;  1ILK A;  4U4T A;  1Y1V D;  4IKW A;  1NBP A;  4BY7 D;  3BPO A;  1M4B A;  4GBZ A;  4Q65 A;  4EXN A;  3DI2 A;  1HZI A;  3NCB A;  4Z5R D;  4OH3 A;  1RFB A;  4DKF A;  4DKE A;  2E9W C;  3D87 A;  1PV6 A;  1IK0 A;  1RW5 A;  4XNJ A;  1FYH A;  4I77 Z;  2H24 A;  1F6F A;  5A2O A;  5IYB D;  2JA8 D;  1EMR A;  4WRL B;  2CYK A;  4J4L C;  5TS9 A;  1I1R B;  3D48 P;  3PO2 D;  2Z3R A;  5EQH A;  3WDO A;  1ETE A;  1LK3 A;  3IRH A;  5D58 A;  4BBR D;  5IYD D;  3G6D A;  1PGR A;  3B5K A;  4NI7 A;  2B5I A;  3LB6 B;  1M4C A;  1VLK A;  1RCB A;  4A3K D;  3O7P A;  2B91 A;  4DOH A;  1FG9 A;  4GBY A;  4ZYR A;  4IU8 A;  2D9Q A;  4A3G D;  1WU3 I;  1AU1 A;  1HWG A; 
#chains in the Genus database with same CATH homology
 1J7V L;  4ZF7 A;  1D9C A;  3HOW D;  5FHX A;  4A3J D;  1V7N V;  1LQS L;  3HOX D;  2ILK A;  4DKD A;  2HYM B;  3OQ3 A;  5IYC D;  2B8U A;  2XQB A;  3BES L;  4BXX D;  1A7M A;  1Z7C A;  1BGE A;  3SE3 B;  3UEZ E;  1IRL A;  1ILK A;  3QT2 C;  1Y6K L;  1EER A;  4YPG C;  2LMS A;  1BUY A;  1BGD A;  1P9M B;  4A3E D;  1Y1V D;  1HUW A;  2D48 A;  2Z3Q A;  3DLQ I;  1NBP A;  3G9V B;  3L5W I;  5D70 A;  1IL6 A;  3BPO A;  2R7Z D;  4BY7 D;  1SCF A;  5E4E A;  1M4B A;  3HMX B;  4A3C D;  1EXZ A;  1AXI A;  1HGU A;  1CYL A;  3HHR A;  1F45 B;  3PIW A;  1CSG A;  4GRW A;  4EXN A;  3DI2 A;  1PW6 A;  2KZ1 A;  2B8Z A;  2B90 A;  4NEM A;  4NEJ A;  1CN4 C;  1HZI A;  3NCB A;  5C44 D;  4A3I D;  2JA7 D;  4Z5R D;  2O27 A;  1ITI A;  3L5X A;  3NCC A;  4PS4 A;  3PIV A;  4A3D D;  1EVS A;  1RFB A;  4CNI C;  4DKF A;  1HUL A;  4DKE A;  3H3V E;  3Q1S I;  2E9W C;  3D87 A;  1ITF A;  4FA8 E;  1Y6M L;  1WCM D;  1IK0 A;  1HIJ A;  3SE4 B;  3S9D A;  3PO3 D;  3DI3 A;  1B5L A;  2OQP A;  3I4M D;  5LQB A;  4BBS D;  1RW5 A;  3EW3 A;  1M4R A;  1N1F A;  4MHL A;  4O9H A;  1GNC A;  1ALU A;  1LKI A;  3FKI D;  3QB1 A;  1FYH A;  3NPZ A;  4I77 Z;  1GA3 A;  2C35 A;  3EJJ A;  3NCF A;  3DGC L;  2H24 A;  1F6F A;  1BP3 A;  3VA2 A;  1Z92 A;  1CD9 A;  1HWH A;  2PSM A;  5IYB D;  3HOV D;  2L3O A;  2JA8 D;  4GS7 A;  3TGX B;  3QAZ A;  1EMR A;  3WCY I;  2O6I A;  3UF5 A;  3QWR B;  1IAR A;  4WRL B;  2CYK A;  5D72 A;  3QB7 A;  5D71 A;  5D22 A;  5FLM D;  1Y6N L;  1AX8 A;  4X51 A;  3D85 C;  1BGC A;  4LRL A;  3UX9 A;  4ZS7 A;  4A3B D;  4RS1 A;  1QVN A;  2Q7N B;  4J4L C;  2B8X A;  1EKU A;  2Q14 A;  5TS9 A;  3AYH A;  3NCE A;  1I1R B;  1V7M V;  3I4N D;  4A93 D;  3D48 P;  3PO2 D;  5L6Y C;  3OG4 A;  2R92 D;  3HOY D;  2Z3R A;  2JA5 D;  1Y14 A;  2IL6 A;  4NN6 A;  1M48 A;  1ETE A;  1LK3 A;  2B8Y A;  2O26 A;  4YQX A;  2B63 D;  1JLI A;  4NKQ C;  4NI9 A;  1BCN A;  5IP9 D;  3BPN A;  3IRH A;  1Y1W D;  4A3F D;  1D9G A;  4BBR D;  1KF9 A;  3G6D A;  1PGR A;  1RHG A;  3B5K A;  4NN5 A;  5IYD D;  4A3M D;  1ITL A;  1ITM A;  4O6K A;  4NI7 A;  2B5I A;  5C3E D;  2Q98 A;  2L3Y A;  1M4C A;  3DUH C;  3LB6 B;  1VLK A;  1YKB A;  1A22 A;  1RCB A;  1PVH B;  3INK C;  4YUE C;  1PY2 A;  4A3K D;  2VUM D;  1IJZ A;  3HHC A;  1CNT 1;  2B91 A;  2ERJ D;  1BBN A;  3LB6 A;  4BY1 D;  4A3L D;  1HIK A;  4DOH A;  1FG9 A;  3N06 A;  5C4X D;  3BPL A;  1M4A A;  5C7X A;  5D28 B;  3HOU D;  3UF2 A;  3H0G D;  5FUC A;  1M47 A;  3MZG A;  4NN7 A;  4DKC A;  3OG6 A;  4YDY I;  1INR A;  2INT A;  2D9Q A;  4A3G D;  1WU3 I;  3N0P A;  2JA6 D;  3HOZ D;  2R93 D;  1M49 A;  1AU1 A;  2GMF A;  5IP7 D;  5KNH I;  2LAG A;  4EXP A;  1HWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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