2R92D

Elongation complex of rna polymerase ii with artificial rdrp scaffold
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/rna
molecule keywords RNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3
publication title Molecular basis of RNA-dependent RNA polymerase II activity.
pubmed doi rcsb
total genus 44
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 2r92D02
5IP7D 3HOUD 5IYBD 3FKID 5FLMD 4BY1D 3HOWD 3HOYD 2R7ZD 3PO2D 4A93D 2R93D 5C4XD 3HOVD 3H0GD 4A3LD 3I4ND 4A3JD 2C35A 2R92D 3PO3D 1Y1WD 4A3DD 3AYHA 4A3GD 5C3ED 2JA6D 1Y1VD 5C44D 1WCMD 3HOZD 4BBSD 4A3ID 4A3MD 3H3VE 2VUMD 5IP9D 1Y14A 5IYDD 2JA8D 4A3BD 4BXXD 4BY7D 3HOXD 4A3ED 2JA5D 2B63D 2JA7D 5IYCD 3I4MD 4BBRD 4A3KD 4A3CD 4A3FD
chains in the Genus database with same CATH superfamily
5IP7D 5IYBD 1M4CA 4YBQA 1RFBA 4X51A 4Z5RD 4JA3A 3PO3D 3NCFA 1AXIA 4W6VA 1CSGA 1Y1VD 1WCMD 2CFQA 3H3VE 5IP9D 2JA8D 3G6DA 2Z3QA 3NPZA 5IYCD 3LB6A 3HOUD 4MHLA 1IARA 5EQGA 3I4ND 4ZW9A 3D85C 1IK0A 4GBZA 4DKDA 2D48A 1BGDA 3HOZD 4TPJA 1GA3A 3UF2A 3O7PA 3PIVA 4YQXA 1LQSL 1D9GA 2B5IA 3S9DA 5C4XD 2Y5YA 1ITIA 1FYHA 2XUTA 2C35A 1WU3I 3O7QA 3NCCA 1EVSA 1N1FA 3QWRB 5C3ED 1RCBA 2JA6D 2OQPA 3HHRA 4J05A 3NCEA 3BPLA 3QT2C 1BCNA 5L6YC 5D28B 4A3CD 3BPNA 1Y6KL 4O6KA 1EKUA 1PGRA 4CNIC 1AU1A 1ITMA 1A22A 1SCFA 4Q65A 5EQHA 1J7VL 4A3ID 5D59A 4BY7D 2ERJD 3QB7A 2R7ZD 1Y6NL 1INRA 1P9MB 1HIJA 1A7MA 3B5KA 1ETEA 4YPGC 5D22A 4UVMA 1M48A 1PV6A 2VUMD 4APSA 4A3BD 4NI7A 1CYLA 4BBRD 4A3FD 4WRLB 3PO2D 2HYMB 1F6FA 3DI2A 4IKWA 4A3JD 4XNIA 4PS4A 1CNT1 3DGCL 5EQIA 2Z3RA 2Q7NB 4EXNA 4U4TA 4ZF7A 4DOHA 2JA7D 4NI9A 4TPGA 4A3GD 1M47A 2B8YA 3FKID 4A93D 5FHXA 4ZS7A 3EJJA 1BGCA 2B8ZA 3NCBA 4A3DD 4DKEA 4YDYI 3G9VB 1LK3A 4DKFA 2XQBA 1HULA 2B63D 4NEJA 1M4RA 3N06A 1Z92A 3QAZA 2ILKA 3WDOA 1PW6A 4I77Z 1ITFA 4JREA 2B91A 2IL6A 2O26A 1QVNA 2LMSA 2V8NA 1Y1WD 4NN6A 4ZWCA 3LB6B 3SE4B 3HHCA 3MZGA 1BGEA 4GRWA 2B90A 4U4VA 1I1RB 3BESL 1RHGA 3UEZE 1FG9A 2B8UA 4BY1D 4QIQA 4TPHA 3PIWA 4OH3A 3DUHC 4GS7A 3AYHA 4NEMA 2CYKA 3D87A 1ALUA 5TS9A 1HGUA 5IYDD 5E4EA 2L3YA 3UX9A 3I4MD 1D9CA 4EXPA 4NKQC 1CD9A 4XNJA 3HOWD 3INKC 4ZWBA 3H0GD 4A3LD 1YKBA 2R92D 4D2CA 2KZ1A 3OQ3A 5LQBA 4YB9D 3EW3A 1GNCA 5D70A 3N0PA 4BBSD 4IKVA 4GC0A 1IL6A 3QB1A 4A3ED 1VLKA 5D6KA 5FLMD 3HOYD 2PSMA 5GXBA 1BP3A 1F45B 1Y6ML 5FUCA 1LKIA 3D48P 1PVHB 1HZIA 1HIKA 2Q14A 1BBNA 4O9HA 5C44D 1EMRA 4LRLA 5A2OA 4RS1A 4BXXD 2JA5D 1HUWA 3HMXB 3OG6A 3L5WI 1EERA 1B5LA 1KF9A 5C7XA 5KNHI 4PYPA 1V7NV 2L3OA 3VA2A 1IJZA 3TGXB 4DKCA 1M4AA 1PW4A 2CFPA 2Q98A 2R93D 4D2DA 1HWHA 4GBYA 4LDSA 1NBPA 1M49A 4A3MD 1IRLA 4IU9A 2INTA 2E9WC 4IU8A 4FA8E 1PV7A 2LAGA 4NN5A 3HOVD 4J4LC 1M4BA 1BUYA 3SE3B 3L5XA 5D72A 4LEPA 4NN7A 4D2BA 1RW5A 1JLIA 5D71A 1ILKA 3Q1SI 2D9QA 3DLQI 3IRHA 1V7MV 3OG4A 5C65A 4U4WA 1CN4C 1Z7CA 3UF5A 5D58A 4A3KD 2H24A 5A2NA 4ZYRA 3BPOA 1AX8A 1PY2A 2O6IA 3WCYI 4JR9A 1HWGA 2GMFA 4IKXA 4IKZA 1EXZA 2B8XA 2O27A 4OAAA 1Y14A 1ITLA 3HOXD 4IKYA 4YUEC 3DI3A
chains in the Genus database with same CATH topology
3QB7A 3OG6A 5IP7D 5IYBD 1M4CA 1Y6NL 1INRA 1BGEA 1RFBA 2R7ZD 1P9MB 4GRWA 2B90A 4X51A 1HIJA 1I1RB 1A7MA 3L5WI 4Z5RD 3B5KA 1EERA 1B5LA 1ETEA 3BESL 4YPGC 5D22A 1KF9A 3PO3D 3NCFA 5C7XA 1RHGA 1AXIA 1M48A 5KNHI 1CSGA 1Y1VD 1WCMD 1V7NV 3UEZE 3H3VE 2VUMD 5IP9D 2JA8D 3G6DA 2L3OA 3VA2A 4A3BD 1IJZA 3WCYI 4NI7A 1FG9A 3TGXB 2Z3QA 4DKCA 1CYLA 3NPZA 2B8UA 5IYCD 3LB6A 4BBRD 1M4AA 4A3FD 4A3DD 3HOUD 4WRLB 4BY1D 3PO2D 2HYMB 2Q98A 2R93D 4MHLA 1F6FA 1IARA 2O6IA 3PIWA 1HWHA 3DI2A 3I4ND 4A3JD 4PS4A 1NBPA 3D85C 1IK0A 1M49A 3DUHC 4GS7A 3AYHA 4DKDA 2D48A 1CNT1 2CYKA 3DGCL 4NEMA 3D87A 2Z3RA 1BGDA 3HOZD 1ALUA 4A3MD 1IRLA 5TS9A 1HGUA 2Q7NB 5IYDD 5E4EA 1GA3A 4EXNA 2INTA 1GNCA 3UF2A 2L3YA 4ZF7A 3UX9A 4DOHA 2E9WC 2JA7D 4FA8E 3PIVA 4NI9A 3I4MD 1D9CA 4EXPA 4NKQC 4YQXA 1CD9A 4A3GD 1M47A 1LQSL 2B8YA 1D9GA 2B5IA 3S9DA 2LAGA 3FKID 3HOWD 3INKC 4A93D 5C4XD 1ITIA 4NN5A 1FYHA 3HOVD 4J4LC 3H0GD 1M4BA 1BUYA 5FHXA 3SE3B 3L5XA 4ZS7A 4A3LD 3EJJA 5D72A 2C35A 1WU3I 1YKBA 1BGCA 3NCCA 2R92D 2B8ZA 2KZ1A 3NCBA 3OQ3A 4NN7A 4DKEA 1EVSA 3EW3A 1N1FA 1RW5A 4YDYI 5LQBA 3QWRB 1JLIA 5D71A 3G9VB 1LK3A 1RCBA 5C3ED 2JA6D 5D70A 1ILKA 3N0PA 2OQPA 3Q1SI 2XQBA 2D9QA 3DLQI 3IRHA 4DKFA 1V7MV 4BBSD 3HHRA 3OG4A 1IL6A 3NCEA 3QB1A 3BPLA 3QT2C 1CN4C 1BCNA 1Z7CA 1HULA 5L6YC 4A3ED 2B63D 5D28B 1VLKA 4NEJA 1M4RA 3UF5A 3N06A 1Z92A 4A3KD 4A3CD 2H24A 2ILKA 3QAZA 1PW6A 3BPNA 5FLMD 3BPOA 4I77Z 1Y6KL 3HOYD 2PSMA 1ITFA 1AX8A 4O6KA 1PY2A 1BP3A 2B91A 1EKUA 2IL6A 1PGRA 1HWGA 1F45B 1AU1A 1Y6ML 2GMFA 1QVNA 2LMSA 2O26A 1LKIA 5FUCA 4CNIC 1ITMA 1EXZA 3D48P 1A22A 1Y1WD 1PVHB 2B8XA 1HZIA 1SCFA 1HIKA 4NN6A 2Q14A 1BBNA 1J7VL 2O27A 4O9HA 3LB6B 1EMRA 3SE4B 5C44D 4A3ID 1Y14A 4LRLA 4RS1A 4BXXD 4BY7D 1ITLA 3HOXD 2JA5D 4YUEC 3HHCA 1HUWA 3DI3A 3HMXB 3MZGA 2ERJD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IP7 D;  3HOU D;  5IYB D;  3FKI D;  5FLM D;  4BY1 D;  3HOW D;  3HOY D;  2R7Z D;  3PO2 D;  4A93 D;  2R93 D;  5C4X D;  3HOV D;  3H0G D;  4A3L D;  3I4N D;  4A3J D;  2C35 A;  2R92 D;  3PO3 D;  1Y1W D;  4A3D D;  3AYH A;  4A3G D;  5C3E D;  2JA6 D;  1Y1V D;  5C44 D;  1WCM D;  3HOZ D;  4BBS D;  4A3I D;  4A3M D;  3H3V E;  2VUM D;  5IP9 D;  1Y14 A;  5IYD D;  2JA8 D;  4A3B D;  4BXX D;  4BY7 D;  3HOX D;  4A3E D;  2JA5 D;  2B63 D;  2JA7 D;  5IYC D;  3I4M D;  4BBR D;  4A3K D;  4A3C D;  4A3F D; 
#chains in the Genus database with same CATH topology
 5IP7 D;  5IYB D;  1M4C A;  4YBQ A;  1RFB A;  4X51 A;  4Z5R D;  4JA3 A;  3PO3 D;  3NCF A;  1AXI A;  4W6V A;  1CSG A;  1Y1V D;  1WCM D;  2CFQ A;  3H3V E;  5IP9 D;  2JA8 D;  3G6D A;  2Z3Q A;  3NPZ A;  5IYC D;  3LB6 A;  3HOU D;  4MHL A;  1IAR A;  5EQG A;  3I4N D;  4ZW9 A;  3D85 C;  1IK0 A;  4GBZ A;  4DKD A;  2D48 A;  1BGD A;  3HOZ D;  4TPJ A;  1GA3 A;  3UF2 A;  3O7P A;  3PIV A;  4YQX A;  1LQS L;  1D9G A;  2B5I A;  3S9D A;  5C4X D;  2Y5Y A;  1ITI A;  1FYH A;  2XUT A;  2C35 A;  1WU3 I;  3O7Q A;  3NCC A;  1EVS A;  1N1F A;  3QWR B;  5C3E D;  1RCB A;  2JA6 D;  2OQP A;  3HHR A;  4J05 A;  3NCE A;  3BPL A;  3QT2 C;  1BCN A;  5L6Y C;  5D28 B;  4A3C D;  3BPN A;  1Y6K L;  4O6K A;  1EKU A;  1PGR A;  4CNI C;  1AU1 A;  1ITM A;  1A22 A;  1SCF A;  4Q65 A;  5EQH A;  1J7V L;  4A3I D;  5D59 A;  4BY7 D;  2ERJ D;  3QB7 A;  2R7Z D;  1Y6N L;  1INR A;  1P9M B;  1HIJ A;  1A7M A;  3B5K A;  1ETE A;  4YPG C;  5D22 A;  4UVM A;  1M48 A;  1PV6 A;  2VUM D;  4APS A;  4A3B D;  4NI7 A;  1CYL A;  4BBR D;  4A3F D;  4WRL B;  3PO2 D;  2HYM B;  1F6F A;  3DI2 A;  4IKW A;  4A3J D;  4XNI A;  4PS4 A;  1CNT 1;  3DGC L;  5EQI A;  2Z3R A;  2Q7N B;  4EXN A;  4U4T A;  4ZF7 A;  4DOH A;  2JA7 D;  4NI9 A;  4TPG A;  4A3G D;  1M47 A;  2B8Y A;  3FKI D;  4A93 D;  5FHX A;  4ZS7 A;  3EJJ A;  1BGC A;  2B8Z A;  3NCB A;  4A3D D;  4DKE A;  4YDY I;  3G9V B;  1LK3 A;  4DKF A;  2XQB A;  1HUL A;  2B63 D;  4NEJ A;  1M4R A;  3N06 A;  1Z92 A;  3QAZ A;  2ILK A;  3WDO A;  1PW6 A;  4I77 Z;  1ITF A;  4JRE A;  2B91 A;  2IL6 A;  2O26 A;  1QVN A;  2LMS A;  2V8N A;  1Y1W D;  4NN6 A;  4ZWC A;  3LB6 B;  3SE4 B;  3HHC A;  3MZG A;  1BGE A;  4GRW A;  2B90 A;  4U4V A;  1I1R B;  3BES L;  1RHG A;  3UEZ E;  1FG9 A;  2B8U A;  4BY1 D;  4QIQ A;  4TPH A;  3PIW A;  4OH3 A;  3DUH C;  4GS7 A;  3AYH A;  4NEM A;  2CYK A;  3D87 A;  1ALU A;  5TS9 A;  1HGU A;  5IYD D;  5E4E A;  2L3Y A;  3UX9 A;  3I4M D;  1D9C A;  4EXP A;  4NKQ C;  1CD9 A;  4XNJ A;  3HOW D;  3INK C;  4ZWB A;  3H0G D;  4A3L D;  1YKB A;  2R92 D;  4D2C A;  2KZ1 A;  3OQ3 A;  5LQB A;  4YB9 D;  3EW3 A;  1GNC A;  5D70 A;  3N0P A;  4BBS D;  4IKV A;  4GC0 A;  1IL6 A;  3QB1 A;  4A3E D;  1VLK A;  5D6K A;  5FLM D;  3HOY D;  2PSM A;  5GXB A;  1BP3 A;  1F45 B;  1Y6M L;  5FUC A;  1LKI A;  3D48 P;  1PVH B;  1HZI A;  1HIK A;  2Q14 A;  1BBN A;  4O9H A;  5C44 D;  1EMR A;  4LRL A;  5A2O A;  4RS1 A;  4BXX D;  2JA5 D;  1HUW A;  3HMX B;  3OG6 A;  3L5W I;  1EER A;  1B5L A;  1KF9 A;  5C7X A;  5KNH I;  4PYP A;  1V7N V;  2L3O A;  3VA2 A;  1IJZ A;  3TGX B;  4DKC A;  1M4A A;  1PW4 A;  2CFP A;  2Q98 A;  2R93 D;  4D2D A;  1HWH A;  4GBY A;  4LDS A;  1NBP A;  1M49 A;  4A3M D;  1IRL A;  4IU9 A;  2INT A;  2E9W C;  4IU8 A;  4FA8 E;  1PV7 A;  2LAG A;  4NN5 A;  3HOV D;  4J4L C;  1M4B A;  1BUY A;  3SE3 B;  3L5X A;  5D72 A;  4LEP A;  4NN7 A;  4D2B A;  1RW5 A;  1JLI A;  5D71 A;  1ILK A;  3Q1S I;  2D9Q A;  3DLQ I;  3IRH A;  1V7M V;  3OG4 A;  5C65 A;  4U4W A;  1CN4 C;  1Z7C A;  3UF5 A;  5D58 A;  4A3K D;  2H24 A;  5A2N A;  4ZYR A;  3BPO A;  1AX8 A;  1PY2 A;  2O6I A;  3WCY I;  4JR9 A;  1HWG A;  2GMF A;  4IKX A;  4IKZ A;  1EXZ A;  2B8X A;  2O27 A;  4OAA A;  1Y14 A;  1ITL A;  3HOX D;  4IKY A;  4YUE C;  3DI3 A; 
#chains in the Genus database with same CATH homology
 3QB7 A;  3OG6 A;  5IP7 D;  5IYB D;  1M4C A;  1Y6N L;  1INR A;  1BGE A;  1RFB A;  2R7Z D;  1P9M B;  4GRW A;  2B90 A;  4X51 A;  1HIJ A;  1I1R B;  1A7M A;  3L5W I;  4Z5R D;  3B5K A;  1EER A;  1B5L A;  1ETE A;  3BES L;  4YPG C;  5D22 A;  1KF9 A;  3PO3 D;  3NCF A;  5C7X A;  1RHG A;  1AXI A;  1M48 A;  5KNH I;  1CSG A;  1Y1V D;  1WCM D;  1V7N V;  3UEZ E;  3H3V E;  2VUM D;  5IP9 D;  2JA8 D;  3G6D A;  2L3O A;  3VA2 A;  4A3B D;  1IJZ A;  3WCY I;  4NI7 A;  1FG9 A;  3TGX B;  2Z3Q A;  4DKC A;  1CYL A;  3NPZ A;  2B8U A;  5IYC D;  3LB6 A;  4BBR D;  1M4A A;  4A3F D;  4A3D D;  3HOU D;  4WRL B;  4BY1 D;  3PO2 D;  2HYM B;  2Q98 A;  2R93 D;  4MHL A;  1F6F A;  1IAR A;  2O6I A;  3PIW A;  1HWH A;  3DI2 A;  3I4N D;  4A3J D;  4PS4 A;  1NBP A;  3D85 C;  1IK0 A;  1M49 A;  3DUH C;  4GS7 A;  3AYH A;  4DKD A;  2D48 A;  1CNT 1;  2CYK A;  3DGC L;  4NEM A;  3D87 A;  2Z3R A;  1BGD A;  3HOZ D;  1ALU A;  4A3M D;  1IRL A;  5TS9 A;  1HGU A;  2Q7N B;  5IYD D;  5E4E A;  1GA3 A;  4EXN A;  2INT A;  1GNC A;  3UF2 A;  2L3Y A;  4ZF7 A;  3UX9 A;  4DOH A;  2E9W C;  2JA7 D;  4FA8 E;  3PIV A;  4NI9 A;  3I4M D;  1D9C A;  4EXP A;  4NKQ C;  4YQX A;  1CD9 A;  4A3G D;  1M47 A;  1LQS L;  2B8Y A;  1D9G A;  2B5I A;  3S9D A;  2LAG A;  3FKI D;  3HOW D;  3INK C;  4A93 D;  5C4X D;  1ITI A;  4NN5 A;  1FYH A;  3HOV D;  4J4L C;  3H0G D;  1M4B A;  1BUY A;  5FHX A;  3SE3 B;  3L5X A;  4ZS7 A;  4A3L D;  3EJJ A;  5D72 A;  2C35 A;  1WU3 I;  1YKB A;  1BGC A;  3NCC A;  2R92 D;  2B8Z A;  2KZ1 A;  3NCB A;  3OQ3 A;  4NN7 A;  4DKE A;  1EVS A;  3EW3 A;  1N1F A;  1RW5 A;  4YDY I;  5LQB A;  3QWR B;  1JLI A;  5D71 A;  3G9V B;  1LK3 A;  1RCB A;  5C3E D;  2JA6 D;  5D70 A;  1ILK A;  3N0P A;  2OQP A;  3Q1S I;  2XQB A;  2D9Q A;  3DLQ I;  3IRH A;  4DKF A;  1V7M V;  4BBS D;  3HHR A;  3OG4 A;  1IL6 A;  3NCE A;  3QB1 A;  3BPL A;  3QT2 C;  1CN4 C;  1BCN A;  1Z7C A;  1HUL A;  5L6Y C;  4A3E D;  2B63 D;  5D28 B;  1VLK A;  4NEJ A;  1M4R A;  3UF5 A;  3N06 A;  1Z92 A;  4A3K D;  4A3C D;  2H24 A;  2ILK A;  3QAZ A;  1PW6 A;  3BPN A;  5FLM D;  3BPO A;  4I77 Z;  1Y6K L;  3HOY D;  2PSM A;  1ITF A;  1AX8 A;  4O6K A;  1PY2 A;  1BP3 A;  2B91 A;  1EKU A;  2IL6 A;  1PGR A;  1HWG A;  1F45 B;  1AU1 A;  1Y6M L;  2GMF A;  1QVN A;  2LMS A;  2O26 A;  1LKI A;  5FUC A;  4CNI C;  1ITM A;  1EXZ A;  3D48 P;  1A22 A;  1Y1W D;  1PVH B;  2B8X A;  1HZI A;  1SCF A;  1HIK A;  4NN6 A;  2Q14 A;  1BBN A;  1J7V L;  2O27 A;  4O9H A;  3LB6 B;  1EMR A;  3SE4 B;  5C44 D;  4A3I D;  1Y14 A;  4LRL A;  4RS1 A;  4BXX D;  4BY7 D;  1ITL A;  3HOX D;  2JA5 D;  4YUE C;  3HHC A;  1HUW A;  3DI3 A;  3HMX B;  3MZG A;  2ERJ D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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