3FKID

12-subunit rna polymerase ii refined with zn-sad data
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
218
structure length
178
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKETREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 42
structure length 178
sequence length 218
ec nomenclature
pdb deposition date 2008-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3fkiD02
3AYHA 3I4MD 1Y1VD 1WCMD 3H0GD 3PO2D 5IYCD 5IYBD 3HOYD 2JA7D 4A93D 2C35A 3I4ND 4BY1D 4BBSD 4BY7D 5FLMD 4A3GD 5C3ED 2B63D 3PO3D 3H3VE 3HOVD 2R93D 3HOWD 5IP9D 4A3ID 3FKID 2R7ZD 2JA6D 3HOUD 5C44D 4A3KD 5IP7D 2JA8D 5IYDD 1Y14A 2R92D 4A3LD 2JA5D 3HOXD 4A3CD 4A3DD 4A3MD 4A3JD 4A3FD 4BXXD 4BBRD 4A3ED 1Y1WD 2VUMD 3HOZD 4A3BD 5C4XD
chains in the Genus database with same CATH superfamily
3N06A 2OQPA 1ILKA 5FUCA 4LRLA 5D22A 4TPJA 3B5KA 1EKUA 4GS7A 4A3FD 1RCBA 2ILKA 4A3BD 5C4XD 4D2CA 3H0GD 5IYCD 4CNIC 1EERA 1WU3I 4GBZA 3G6DA 5FHXA 3VA2A 1M4CA 1CD9A 1CSGA 4Z5RD 5IP9D 1F45B 4NN5A 3SE4B 2LAGA 1EMRA 4IKVA 4TPHA 4O9HA 4D2DA 1IL6A 1PW4A 2C35A 1YKBA 1BGCA 2B8UA 2PSMA 2B63D 4PYPA 2INTA 2IL6A 2B91A 1Z92A 3L5WI 5D70A 2Z3QA 3BPOA 1Y6ML 5A2OA 1HGUA 3TGXB 1M49A 3HHRA 2D9QA 5D72A 5FLMD 1Y6NL 5D6KA 4A3CD 4ZS7A 4ZW9A 3D87A 3BPLA 4YUEC 4MHLA 1A7MA 3I4MD 4ZWCA 3NPZA 4LDSA 2B8ZA 1NBPA 1M4AA 1ITFA 4O6KA 2XUTA 4DKCA 1BCNA 2B5IA 3DI2A 5GXBA 1BGDA 1ITIA 1M47A 4IU8A 4IKZA 5D58A 4ZF7A 2KZ1A 4APSA 1HULA 3UEZE 3D85C 3QT2C 5D59A 1JLIA 3SE3B 4IKYA 3IRHA 2Y5YA 4UVMA 2GMFA 3HOUD 2XQBA 1PY2A 2D48A 4TPGA 3UF2A 1HIJA 4U4TA 4A93D 3QWRB 4BY7D 4YB9D 5IP7D 4X51A 1EVSA 3UF5A 3D48P 1PV6A 4DKFA 1INRA 3OQ3A 1BP3A 3QAZA 1KF9A 1BBNA 2Q14A 1IJZA 5LQBA 3HMXB 4GC0A 5D71A 3HHCA 4GRWA 1LKIA 4DOHA 1CNT1 3L5XA 4D2BA 1ITMA 3PO2D 1I1RB 4JREA 3INKC 1J7VL 1PGRA 1LK3A 3H3VE 5EQGA 3FKID 2O6IA 2R7ZD 3N0PA 3BPNA 1V7MV 4XNJA 4ZWBA 2L3OA 3NCFA 4ZYRA 2L3YA 2JA5D 4EXPA 4QIQA 4A3MD 4WRLB 1LQSL 4BXXD 4Q65A 5TS9A 1BUYA 4LEPA 5IYBD 1M4RA 2O27A 2HYMB 1ETEA 4JR9A 2LMSA 1RHGA 4BBRD 1Y1WD 1GNCA 3S9DA 3DLQI 3DI3A 4W6VA 1M4BA 1SCFA 4RS1A 3EJJA 5C65A 1ALUA 1F6FA 1HWHA 1HWGA 2CFPA 4IU9A 4IKWA 3HOVD 4GBYA 4IKXA 4NN7A 1HIKA 5EQIA 4YBQA 4U4VA 1IRLA 4FA8E 4A3KD 4DKDA 2B8YA 4OH3A 1HUWA 1M48A 3WDOA 3HOXD 4A3JD 1AX8A 3NCCA 1QVNA 4I77Z 1IK0A 1Y1VD 1FG9A 3G9VB 1V7NV 2ERJD 1GA3A 4NI7A 1FYHA 3PIWA 5EQHA 2Z3RA 1RW5A 4J05A 1VLKA 5C44D 1Y6KL 1Y14A 3MZGA 5KNHI 1EXZA 1P9MB 3QB1A 1BGEA 4JA3A 2H24A 5L6YC 1N1FA 4EXNA 4NEJA 3NCEA 3QB7A 4BY1D 2V8NA 3HOWD 2Q98A 4YPGC 2JA8D 5C7XA 2R92D 2E9WC 1D9GA 2O26A 3WCYI 3O7PA 1AU1A 3UX9A 1AXIA 2B90A 3LB6B 3NCBA 3PIVA 4A3GD 3PO3D 1D9CA 2R93D 2JA6D 2CYKA 5IYDD 3OG6A 4A3DD 2B8XA 5D28B 4A3ED 4U4WA 3LB6A 1PV7A 1PW6A 3HOZD 3AYHA 3EW3A 3BESL 1CN4C 4NN6A 3HOYD 2JA7D 4BBSD 4NEMA 4YQXA 4DKEA 3DUHC 4XNIA 4A3ID 1Z7CA 5A2NA 1RFBA 4OAAA 3Q1SI 1WCMD 1ITLA 4YDYI 2CFQA 4NKQC 1IARA 3OG4A 4PS4A 3I4ND 2Q7NB 5C3ED 5E4EA 4J4LC 1HZIA 4NI9A 1B5LA 1CYLA 1A22A 1PVHB 4A3LD 3DGCL 3O7QA 2VUMD
chains in the Genus database with same CATH topology
1A7MA 1N1FA 3I4MD 4EXNA 4NEJA 3L5XA 3N06A 1ITMA 3NPZA 3PO2D 1I1RB 2B8ZA 1NBPA 3NCEA 1M4AA 1ITFA 4O6KA 3QB7A 2OQPA 3INKC 4DKCA 1J7VL 4BY1D 1PGRA 2B5IA 1BCNA 1LK3A 1ILKA 5FUCA 3DI2A 3H3VE 4LRLA 5D22A 1BGDA 3B5KA 3HOWD 2Q98A 3FKID 1ITIA 1M47A 2O6IA 2R7ZD 3N0PA 4YPGC 4MHLA 3BPNA 1V7MV 1EKUA 2JA8D 5C7XA 2L3OA 3NCFA 2R92D 2E9WC 2L3YA 4GS7A 2JA5D 4EXPA 4A3MD 4WRLB 4ZF7A 1D9GA 1LQSL 4A3FD 1RCBA 2O26A 2ILKA 3WCYI 2KZ1A 4BXXD 5TS9A 4A3BD 5C4XD 3H0GD 1AU1A 1BUYA 4CNIC 1HULA 1EERA 3UEZE 3UX9A 5IYCD 1AXIA 2B90A 3D85C 3QT2C 5IYBD 1WU3I 3G6DA 1M4RA 3LB6B 5FHXA 3VA2A 1JLIA 1M4CA 1CD9A 3SE3B 3NCBA 3PIVA 4A3GD 1CSGA 4Z5RD 3PO3D 1D9CA 2R93D 2O27A 3IRHA 5IP9D 2HYMB 1F45B 4NN5A 2JA6D 2GMFA 1ETEA 3HOUD 3SE4B 2CYKA 2LMSA 5IYDD 2LAGA 1EMRA 1RHGA 3OG6A 4A3DD 2XQBA 1PY2A 2B8XA 2D48A 5D28B 4O9HA 4BBRD 3LB6A 3UF2A 1PW6A 4A3ED 1Y1WD 3S9DA 3HOZD 1GNCA 3AYHA 3DLQI 3DI3A 3EW3A 1M4BA 1SCFA 4RS1A 3BESL 3EJJA 1IL6A 1CN4C 1ALUA 1F6FA 1HWHA 1HIJA 1HWGA 4NN6A 2JA7D 3QWRB 2C35A 3HOYD 4A93D 1YKBA 1BGCA 2B8UA 4BBSD 4NEMA 4BY7D 4YQXA 4DKEA 2PSMA 2B63D 3HOVD 4GRWA 3DUHC 4NN7A 1HIKA 2INTA 4A3ID 1Z7CA 1RFBA 4A3KD 1IRLA 5IP7D 4FA8E 4DKDA 4X51A 2IL6A 2B8YA 2B91A 1HUWA 1M48A 1Z92A 3L5WI 3HOXD 5D70A 2Z3QA 4A3JD 3BPOA 1AX8A 1CYLA 1EVSA 1QVNA 1Y6ML 3NCCA 4I77Z 3Q1SI 3UF5A 1IK0A 1WCMD 1Y1VD 1ITLA 1FG9A 4YDYI 3G9VB 1V7NV 2ERJD 4NKQC 1GA3A 3D48P 1HGUA 1IARA 3OG4A 4PS4A 4NI7A 1FYHA 3TGXB 3I4ND 2Q7NB 3PIWA 1M49A 3HHRA 2D9QA 5D72A 4DKFA 5FLMD 5C3ED 1INRA 1Y6NL 2Z3RA 3OQ3A 5E4EA 1RW5A 4J4LC 1BP3A 1VLKA 3QAZA 5C44D 1HZIA 4NI9A 1KF9A 1B5LA 1Y6KL 1Y14A 3MZGA 1A22A 1BBNA 1PVHB 2Q14A 1IJZA 5KNHI 5LQBA 4A3LD 1EXZA 3DGCL 3HMXB 4A3CD 1P9MB 4ZS7A 3QB1A 1BGEA 3HHCA 3D87A 5D71A 2VUMD 2H24A 1LKIA 3BPLA 4DOHA 5L6YC 4YUEC 1CNT1
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AYH A;  3I4M D;  1Y1V D;  1WCM D;  3H0G D;  3PO2 D;  5IYC D;  5IYB D;  3HOY D;  2JA7 D;  4A93 D;  2C35 A;  3I4N D;  4BY1 D;  4BBS D;  4BY7 D;  5FLM D;  4A3G D;  5C3E D;  2B63 D;  3PO3 D;  3H3V E;  3HOV D;  2R93 D;  3HOW D;  5IP9 D;  4A3I D;  3FKI D;  2R7Z D;  2JA6 D;  3HOU D;  5C44 D;  4A3K D;  5IP7 D;  2JA8 D;  5IYD D;  1Y14 A;  2R92 D;  4A3L D;  2JA5 D;  3HOX D;  4A3C D;  4A3D D;  4A3M D;  4A3J D;  4A3F D;  4BXX D;  4BBR D;  4A3E D;  1Y1W D;  2VUM D;  3HOZ D;  4A3B D;  5C4X D; 
#chains in the Genus database with same CATH topology
 3N06 A;  2OQP A;  1ILK A;  5FUC A;  4LRL A;  5D22 A;  4TPJ A;  3B5K A;  1EKU A;  4GS7 A;  4A3F D;  1RCB A;  2ILK A;  4A3B D;  5C4X D;  4D2C A;  3H0G D;  5IYC D;  4CNI C;  1EER A;  1WU3 I;  4GBZ A;  3G6D A;  5FHX A;  3VA2 A;  1M4C A;  1CD9 A;  1CSG A;  4Z5R D;  5IP9 D;  1F45 B;  4NN5 A;  3SE4 B;  2LAG A;  1EMR A;  4IKV A;  4TPH A;  4O9H A;  4D2D A;  1IL6 A;  1PW4 A;  2C35 A;  1YKB A;  1BGC A;  2B8U A;  2PSM A;  2B63 D;  4PYP A;  2INT A;  2IL6 A;  2B91 A;  1Z92 A;  3L5W I;  5D70 A;  2Z3Q A;  3BPO A;  1Y6M L;  5A2O A;  1HGU A;  3TGX B;  1M49 A;  3HHR A;  2D9Q A;  5D72 A;  5FLM D;  1Y6N L;  5D6K A;  4A3C D;  4ZS7 A;  4ZW9 A;  3D87 A;  3BPL A;  4YUE C;  4MHL A;  1A7M A;  3I4M D;  4ZWC A;  3NPZ A;  4LDS A;  2B8Z A;  1NBP A;  1M4A A;  1ITF A;  4O6K A;  2XUT A;  4DKC A;  1BCN A;  2B5I A;  3DI2 A;  5GXB A;  1BGD A;  1ITI A;  1M47 A;  4IU8 A;  4IKZ A;  5D58 A;  4ZF7 A;  2KZ1 A;  4APS A;  1HUL A;  3UEZ E;  3D85 C;  3QT2 C;  5D59 A;  1JLI A;  3SE3 B;  4IKY A;  3IRH A;  2Y5Y A;  4UVM A;  2GMF A;  3HOU D;  2XQB A;  1PY2 A;  2D48 A;  4TPG A;  3UF2 A;  1HIJ A;  4U4T A;  4A93 D;  3QWR B;  4BY7 D;  4YB9 D;  5IP7 D;  4X51 A;  1EVS A;  3UF5 A;  3D48 P;  1PV6 A;  4DKF A;  1INR A;  3OQ3 A;  1BP3 A;  3QAZ A;  1KF9 A;  1BBN A;  2Q14 A;  1IJZ A;  5LQB A;  3HMX B;  4GC0 A;  5D71 A;  3HHC A;  4GRW A;  1LKI A;  4DOH A;  1CNT 1;  3L5X A;  4D2B A;  1ITM A;  3PO2 D;  1I1R B;  4JRE A;  3INK C;  1J7V L;  1PGR A;  1LK3 A;  3H3V E;  5EQG A;  3FKI D;  2O6I A;  2R7Z D;  3N0P A;  3BPN A;  1V7M V;  4XNJ A;  4ZWB A;  2L3O A;  3NCF A;  4ZYR A;  2L3Y A;  2JA5 D;  4EXP A;  4QIQ A;  4A3M D;  4WRL B;  1LQS L;  4BXX D;  4Q65 A;  5TS9 A;  1BUY A;  4LEP A;  5IYB D;  1M4R A;  2O27 A;  2HYM B;  1ETE A;  4JR9 A;  2LMS A;  1RHG A;  4BBR D;  1Y1W D;  1GNC A;  3S9D A;  3DLQ I;  3DI3 A;  4W6V A;  1M4B A;  1SCF A;  4RS1 A;  3EJJ A;  5C65 A;  1ALU A;  1F6F A;  1HWH A;  1HWG A;  2CFP A;  4IU9 A;  4IKW A;  3HOV D;  4GBY A;  4IKX A;  4NN7 A;  1HIK A;  5EQI A;  4YBQ A;  4U4V A;  1IRL A;  4FA8 E;  4A3K D;  4DKD A;  2B8Y A;  4OH3 A;  1HUW A;  1M48 A;  3WDO A;  3HOX D;  4A3J D;  1AX8 A;  3NCC A;  1QVN A;  4I77 Z;  1IK0 A;  1Y1V D;  1FG9 A;  3G9V B;  1V7N V;  2ERJ D;  1GA3 A;  4NI7 A;  1FYH A;  3PIW A;  5EQH A;  2Z3R A;  1RW5 A;  4J05 A;  1VLK A;  5C44 D;  1Y6K L;  1Y14 A;  3MZG A;  5KNH I;  1EXZ A;  1P9M B;  3QB1 A;  1BGE A;  4JA3 A;  2H24 A;  5L6Y C;  1N1F A;  4EXN A;  4NEJ A;  3NCE A;  3QB7 A;  4BY1 D;  2V8N A;  3HOW D;  2Q98 A;  4YPG C;  2JA8 D;  5C7X A;  2R92 D;  2E9W C;  1D9G A;  2O26 A;  3WCY I;  3O7P A;  1AU1 A;  3UX9 A;  1AXI A;  2B90 A;  3LB6 B;  3NCB A;  3PIV A;  4A3G D;  3PO3 D;  1D9C A;  2R93 D;  2JA6 D;  2CYK A;  5IYD D;  3OG6 A;  4A3D D;  2B8X A;  5D28 B;  4A3E D;  4U4W A;  3LB6 A;  1PV7 A;  1PW6 A;  3HOZ D;  3AYH A;  3EW3 A;  3BES L;  1CN4 C;  4NN6 A;  3HOY D;  2JA7 D;  4BBS D;  4NEM A;  4YQX A;  4DKE A;  3DUH C;  4XNI A;  4A3I D;  1Z7C A;  5A2N A;  1RFB A;  4OAA A;  3Q1S I;  1WCM D;  1ITL A;  4YDY I;  2CFQ A;  4NKQ C;  1IAR A;  3OG4 A;  4PS4 A;  3I4N D;  2Q7N B;  5C3E D;  5E4E A;  4J4L C;  1HZI A;  4NI9 A;  1B5L A;  1CYL A;  1A22 A;  1PVH B;  4A3L D;  3DGC L;  3O7Q A;  2VUM D; 
#chains in the Genus database with same CATH homology
 1A7M A;  1N1F A;  3I4M D;  4EXN A;  4NEJ A;  3L5X A;  3N06 A;  1ITM A;  3NPZ A;  3PO2 D;  1I1R B;  2B8Z A;  1NBP A;  3NCE A;  1M4A A;  1ITF A;  4O6K A;  3QB7 A;  2OQP A;  3INK C;  4DKC A;  1J7V L;  4BY1 D;  1PGR A;  2B5I A;  1BCN A;  1LK3 A;  1ILK A;  5FUC A;  3DI2 A;  3H3V E;  4LRL A;  5D22 A;  1BGD A;  3B5K A;  3HOW D;  2Q98 A;  3FKI D;  1ITI A;  1M47 A;  2O6I A;  2R7Z D;  3N0P A;  4YPG C;  4MHL A;  3BPN A;  1V7M V;  1EKU A;  2JA8 D;  5C7X A;  2L3O A;  3NCF A;  2R92 D;  2E9W C;  2L3Y A;  4GS7 A;  2JA5 D;  4EXP A;  4A3M D;  4WRL B;  4ZF7 A;  1D9G A;  1LQS L;  4A3F D;  1RCB A;  2O26 A;  2ILK A;  3WCY I;  2KZ1 A;  4BXX D;  5TS9 A;  4A3B D;  5C4X D;  3H0G D;  1AU1 A;  1BUY A;  4CNI C;  1HUL A;  1EER A;  3UEZ E;  3UX9 A;  5IYC D;  1AXI A;  2B90 A;  3D85 C;  3QT2 C;  5IYB D;  1WU3 I;  3G6D A;  1M4R A;  3LB6 B;  5FHX A;  3VA2 A;  1JLI A;  1M4C A;  1CD9 A;  3SE3 B;  3NCB A;  3PIV A;  4A3G D;  1CSG A;  4Z5R D;  3PO3 D;  1D9C A;  2R93 D;  2O27 A;  3IRH A;  5IP9 D;  2HYM B;  1F45 B;  4NN5 A;  2JA6 D;  2GMF A;  1ETE A;  3HOU D;  3SE4 B;  2CYK A;  2LMS A;  5IYD D;  2LAG A;  1EMR A;  1RHG A;  3OG6 A;  4A3D D;  2XQB A;  1PY2 A;  2B8X A;  2D48 A;  5D28 B;  4O9H A;  4BBR D;  3LB6 A;  3UF2 A;  1PW6 A;  4A3E D;  1Y1W D;  3S9D A;  3HOZ D;  1GNC A;  3AYH A;  3DLQ I;  3DI3 A;  3EW3 A;  1M4B A;  1SCF A;  4RS1 A;  3BES L;  3EJJ A;  1IL6 A;  1CN4 C;  1ALU A;  1F6F A;  1HWH A;  1HIJ A;  1HWG A;  4NN6 A;  2JA7 D;  3QWR B;  2C35 A;  3HOY D;  4A93 D;  1YKB A;  1BGC A;  2B8U A;  4BBS D;  4NEM A;  4BY7 D;  4YQX A;  4DKE A;  2PSM A;  2B63 D;  3HOV D;  4GRW A;  3DUH C;  4NN7 A;  1HIK A;  2INT A;  4A3I D;  1Z7C A;  1RFB A;  4A3K D;  1IRL A;  5IP7 D;  4FA8 E;  4DKD A;  4X51 A;  2IL6 A;  2B8Y A;  2B91 A;  1HUW A;  1M48 A;  1Z92 A;  3L5W I;  3HOX D;  5D70 A;  2Z3Q A;  4A3J D;  3BPO A;  1AX8 A;  1CYL A;  1EVS A;  1QVN A;  1Y6M L;  3NCC A;  4I77 Z;  3Q1S I;  3UF5 A;  1IK0 A;  1WCM D;  1Y1V D;  1ITL A;  1FG9 A;  4YDY I;  3G9V B;  1V7N V;  2ERJ D;  4NKQ C;  1GA3 A;  3D48 P;  1HGU A;  1IAR A;  3OG4 A;  4PS4 A;  4NI7 A;  1FYH A;  3TGX B;  3I4N D;  2Q7N B;  3PIW A;  1M49 A;  3HHR A;  2D9Q A;  5D72 A;  4DKF A;  5FLM D;  5C3E D;  1INR A;  1Y6N L;  2Z3R A;  3OQ3 A;  5E4E A;  1RW5 A;  4J4L C;  1BP3 A;  1VLK A;  3QAZ A;  5C44 D;  1HZI A;  4NI9 A;  1KF9 A;  1B5L A;  1Y6K L;  1Y14 A;  3MZG A;  1A22 A;  1BBN A;  1PVH B;  2Q14 A;  1IJZ A;  5KNH I;  5LQB A;  4A3L D;  1EXZ A;  3DGC L;  3HMX B;  4A3C D;  1P9M B;  4ZS7 A;  3QB1 A;  1BGE A;  3HHC A;  3D87 A;  5D71 A;  2VUM D;  2H24 A;  1LKI A;  3BPL A;  4DOH A;  5L6Y C;  4YUE C;  1CNT 1; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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