3HOVD

Complete rna polymerase ii elongation complex ii
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription, transferase/dna/rna
publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 48
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3hovD02
3H0GD 3HOWD 3HOZD 3PO3D 1Y1WD 4BY1D 5C3ED 4BY7D 5C44D 2JA8D 2B63D 3PO2D 4A3ID 4A3KD 2R93D 4A93D 2VUMD 5C4XD 3FKID 2R92D 5FLMD 4A3DD 1Y14A 5IYCD 5IYBD 4A3MD 2JA7D 4BBSD 4A3GD 2R7ZD 1WCMD 2JA6D 4BBRD 3HOUD 4BXXD 3HOVD 4A3CD 5IP9D 3I4ND 1Y1VD 3HOYD 4A3ED 3I4MD 4A3LD 3HOXD 3AYHA 2C35A 4A3JD 3H3VE 5IYDD 2JA5D 4A3BD 4A3FD 5IP7D
chains in the Genus database with same CATH superfamily
1ETEA 2B8UA 4NEJA 4NEMA 4YBQA 4EXNA 1LK3A 2B8XA 4YPGC 5GXBA 4BBSD 4OH3A 4APSA 1M47A 4BXXD 4PS4A 2E9WC 3WDOA 4MHLA 1INRA 3Q1SI 4A3LD 2C35A 3O7QA 1M49A 3VA2A 3DUHC 3S9DA 1ILKA 1AXIA 1BGDA 3N0PA 4UVMA 2PSMA 1PGRA 5TS9A 1IJZA 1M4BA 4JREA 3OG6A 1PY2A 3H0GD 3OG4A 1Y6ML 4YDYI 2B8ZA 2VUMD 4GS7A 5EQGA 1BUYA 5KNHI 1PV6A 4LDSA 1CD9A 5EQIA 3O7PA 4QIQA 1V7MV 5FUCA 2H24A 5EQHA 1Y1WD 2R93D 4GBZA 2O26A 4PYPA 4O9HA 1A7MA 2CFQA 3BPNA 3UF2A 3HOXD 1FG9A 3QAZA 1WU3I 2L3YA 3NCEA 2Q98A 4BY7D 2GMFA 3DLQI 5C44D 1Y6KL 3OQ3A 4NI7A 4U4VA 1IK0A 1N1FA 1P9MB 1JLIA 1HWHA 3D48P 1RHGA 1EVSA 1J7VL 3NCFA 3H3VE 2Q14A 3SE3B 4IKZA 5D71A 2B63D 4DKFA 4U4TA 3HHCA 4XNIA 5D22A 4GC0A 5FLMD 4XNJA 2HYMB 1V7NV 1Y1VD 1IRLA 1IARA 2IL6A 5IYDD 2INTA 5D72A 4YUEC 4ZWBA 1M48A 5L6YC 1ITMA 4DKCA 2R92D 3INKC 3SE4B 1D9CA 3I4ND 5D59A 1GNCA 1EXZA 1HGUA 3AYHA 3QWRB 1BCNA 4NI9A 1RW5A 5IP7D 5A2OA 3HOZD 4DOHA 2LMSA 3UF5A 4OAAA 5C3ED 3MZGA 1A22A 4ZYRA 3D85C 3L5XA 5D58A 2JA7D 2O6IA 2R7ZD 2LAGA 5LQBA 1ALUA 4J05A 5FHXA 3DI3A 4J4LC 5C7XA 4LRLA 3G6DA 4IU9A 1HIJA 4EXPA 3L5WI 2CYKA 4A3KD 1GA3A 4TPJA 1YKBA 1BP3A 3FKID 4WRLB 4A3GD 1M4CA 4NKQC 2Q7NB 5D70A 4A3ED 4GRWA 4NN7A 4W6VA 1HUWA 1F6FA 1RFBA 4GBYA 4NN5A 1CYLA 3PO3D 4BY1D 1AX8A 1Y6NL 4ZS7A 5C4XD 1EMRA 5IYBD 2XUTA 1PW4A 1Z92A 4RS1A 3EW3A 1ITLA 1CNT1 1I1RB 4A3JD 1LKIA 3DGCL 4D2CA 5E4EA 1Y14A 4A3MD 4Z5RD 3UEZE 3G9VB 3HOVD 5IP9D 3NCBA 2O27A 1SCFA 3HHRA 3HMXB 1HZIA 1EERA 3PIVA 4ZF7A 2B8YA 1CSGA 3EJJA 3PO2D 4A3ID 3B5KA 3LB6B 3PIWA 4CNIC 1BGCA 1EKUA 2Z3RA 3I4MD 5D6KA 4IKYA 1QVNA 2B5IA 4TPGA 4JA3A 1PV7A 2B90A 3NCCA 4X51A 3QB1A 4IKXA 2V8NA 4D2DA 3QB7A 1ITIA 1RCBA 2JA8D 5D28B 5C65A 4NN6A 4A3DD 5IYCD 4ZW9A 1FYHA 4O6KA 5A2NA 3UX9A 4DKEA 3LB6A 2JA5D 4LEPA 2XQBA 3HOWD 1BBNA 2Z3QA 1KF9A 3D87A 1PVHB 3BPLA 2ILKA 4BBRD 4TPHA 4Q65A 4ZWCA 1ITFA 1B5LA 1F45B 3QT2C 1LQSL 4A3BD 3BPOA 3NPZA 1Z7CA 4A93D 4U4WA 1HWGA 1IL6A 1PW6A 3BESL 3TGXB 1VLKA 2ERJD 1WCMD 3HOUD 3WCYI 2D9QA 4I77Z 3N06A 2Y5YA 4YB9D 2OQPA 4IKWA 2KZ1A 1NBPA 3DI2A 1HULA 4FA8E 4IKVA 1HIKA 1D9GA 2B91A 2CFPA 1CN4C 1M4RA 4IU8A 2D48A 2JA6D 1M4AA 4A3CD 3HOYD 4DKDA 2L3OA 4JR9A 1AU1A 1BGEA 4A3FD 3IRHA 4YQXA 4D2BA
chains in the Genus database with same CATH topology
3NCEA 2Q98A 3QB7A 1ITIA 1RCBA 4BY7D 2GMFA 1ETEA 2B8UA 3DLQI 2CYKA 3L5WI 4NEJA 5D28B 5C44D 4A3KD 4NN6A 4NEMA 4EXNA 1GA3A 1LK3A 2B8XA 4YPGC 1BP3A 1Y6KL 3FKID 4WRLB 3OQ3A 4NI7A 4A3DD 5IYCD 4BBSD 4A3GD 1M4CA 1M47A 4NKQC 1N1FA 1IK0A 4BXXD 1P9MB 2Q7NB 1JLIA 1HWHA 4PS4A 1FYHA 4O6KA 5D70A 2E9WC 4MHLA 4A3ED 4GRWA 1INRA 3Q1SI 4A3LD 3D48P 1RHGA 1EVSA 1J7VL 2C35A 3NCFA 4NN7A 3UX9A 4DKEA 3LB6A 1HUWA 2JA5D 3H3VE 2XQBA 1F6FA 1RFBA 4NN5A 1CYLA 2Q14A 3HOWD 3SE3B 1BBNA 2JA8D 5D71A 3PO3D 4BY1D 1AX8A 1M49A 2Z3QA 5KNHI 1Y6NL 2B63D 4DKFA 3VA2A 3DUHC 3HHCA 1KF9A 3D87A 3S9DA 4ZS7A 5C4XD 1ILKA 1AXIA 5D22A 1EMRA 5FLMD 1PVHB 3BPLA 5IYBD 2ILKA 1Z92A 1BGDA 4BBRD 2HYMB 3N0PA 1V7NV 1Y1VD 4RS1A 3EW3A 1ITLA 1IRLA 2PSMA 1IARA 1CNT1 2IL6A 1I1RB 1B5LA 1PGRA 1F45B 4A3JD 5TS9A 1ITFA 1IJZA 5IYDD 1LKIA 1LQSL 1M4BA 3BPOA 2INTA 3OG6A 3QT2C 1PY2A 5D72A 4A3BD 3H0GD 3DGCL 4YUEC 3OG4A 1M48A 1Y6ML 4YDYI 3NPZA 3IRHA 1Z7CA 5E4EA 2B8ZA 5L6YC 4A93D 4YQXA 1HWGA 1IL6A 1ITMA 2VUMD 1PW6A 3BESL 4DKCA 2R92D 3TGXB 1Y14A 4A3MD 1VLKA 4GS7A 3INKC 2ERJD 3SE4B 1BUYA 1WCMD 4Z5RD 3UEZE 3WCYI 1D9CA 1CD9A 2D9QA 3G9VB 3NCBA 5IP9D 3HOUD 3HOVD 3I4ND 2O27A 4I77Z 1GNCA 3N06A 1EXZA 1SCFA 3HHRA 3HMXB 1HGUA 1HZIA 3AYHA 1EERA 2OQPA 3QWRB 1BCNA 4NI9A 3PIVA 1V7MV 4ZF7A 2KZ1A 1NBPA 5FUCA 1RW5A 2H24A 5IP7D 3HOZD 2B8YA 3DI2A 1HULA 1CSGA 2LMSA 3UF5A 4DOHA 4FA8E 1Y1WD 5C3ED 3MZGA 3EJJA 1A22A 1HIKA 1D9GA 2B91A 3PO2D 4A3ID 1CN4C 3B5KA 1M4RA 2R93D 3D85C 3L5XA 2O26A 3LB6B 3PIWA 4CNIC 2JA7D 4O9HA 2D48A 2O6IA 2R7ZD 1A7MA 2LAGA 5LQBA 2JA6D 1BGCA 1ALUA 1M4AA 4A3CD 1EKUA 3HOYD 4DKDA 2Z3RA 3BPNA 3I4MD 3UF2A 5FHXA 3HOXD 1QVNA 3DI3A 1FG9A 2B5IA 4J4LC 5C7XA 3QAZA 1AU1A 1BGEA 1WU3I 2B90A 3G6DA 3NCCA 4LRLA 4X51A 2L3YA 2L3OA 3QB1A 1HIJA 1YKBA 4EXPA 4A3FD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H0G D;  3HOW D;  3HOZ D;  3PO3 D;  1Y1W D;  4BY1 D;  5C3E D;  4BY7 D;  5C44 D;  2JA8 D;  2B63 D;  3PO2 D;  4A3I D;  4A3K D;  2R93 D;  4A93 D;  2VUM D;  5C4X D;  3FKI D;  2R92 D;  5FLM D;  4A3D D;  1Y14 A;  5IYC D;  5IYB D;  4A3M D;  2JA7 D;  4BBS D;  4A3G D;  2R7Z D;  1WCM D;  2JA6 D;  4BBR D;  3HOU D;  4BXX D;  3HOV D;  4A3C D;  5IP9 D;  3I4N D;  1Y1V D;  3HOY D;  4A3E D;  3I4M D;  4A3L D;  3HOX D;  3AYH A;  2C35 A;  4A3J D;  3H3V E;  5IYD D;  2JA5 D;  4A3B D;  4A3F D;  5IP7 D; 
#chains in the Genus database with same CATH topology
 1ETE A;  2B8U A;  4NEJ A;  4NEM A;  4YBQ A;  4EXN A;  1LK3 A;  2B8X A;  4YPG C;  5GXB A;  4BBS D;  4OH3 A;  4APS A;  1M47 A;  4BXX D;  4PS4 A;  2E9W C;  3WDO A;  4MHL A;  1INR A;  3Q1S I;  4A3L D;  2C35 A;  3O7Q A;  1M49 A;  3VA2 A;  3DUH C;  3S9D A;  1ILK A;  1AXI A;  1BGD A;  3N0P A;  4UVM A;  2PSM A;  1PGR A;  5TS9 A;  1IJZ A;  1M4B A;  4JRE A;  3OG6 A;  1PY2 A;  3H0G D;  3OG4 A;  1Y6M L;  4YDY I;  2B8Z A;  2VUM D;  4GS7 A;  5EQG A;  1BUY A;  5KNH I;  1PV6 A;  4LDS A;  1CD9 A;  5EQI A;  3O7P A;  4QIQ A;  1V7M V;  5FUC A;  2H24 A;  5EQH A;  1Y1W D;  2R93 D;  4GBZ A;  2O26 A;  4PYP A;  4O9H A;  1A7M A;  2CFQ A;  3BPN A;  3UF2 A;  3HOX D;  1FG9 A;  3QAZ A;  1WU3 I;  2L3Y A;  3NCE A;  2Q98 A;  4BY7 D;  2GMF A;  3DLQ I;  5C44 D;  1Y6K L;  3OQ3 A;  4NI7 A;  4U4V A;  1IK0 A;  1N1F A;  1P9M B;  1JLI A;  1HWH A;  3D48 P;  1RHG A;  1EVS A;  1J7V L;  3NCF A;  3H3V E;  2Q14 A;  3SE3 B;  4IKZ A;  5D71 A;  2B63 D;  4DKF A;  4U4T A;  3HHC A;  4XNI A;  5D22 A;  4GC0 A;  5FLM D;  4XNJ A;  2HYM B;  1V7N V;  1Y1V D;  1IRL A;  1IAR A;  2IL6 A;  5IYD D;  2INT A;  5D72 A;  4YUE C;  4ZWB A;  1M48 A;  5L6Y C;  1ITM A;  4DKC A;  2R92 D;  3INK C;  3SE4 B;  1D9C A;  3I4N D;  5D59 A;  1GNC A;  1EXZ A;  1HGU A;  3AYH A;  3QWR B;  1BCN A;  4NI9 A;  1RW5 A;  5IP7 D;  5A2O A;  3HOZ D;  4DOH A;  2LMS A;  3UF5 A;  4OAA A;  5C3E D;  3MZG A;  1A22 A;  4ZYR A;  3D85 C;  3L5X A;  5D58 A;  2JA7 D;  2O6I A;  2R7Z D;  2LAG A;  5LQB A;  1ALU A;  4J05 A;  5FHX A;  3DI3 A;  4J4L C;  5C7X A;  4LRL A;  3G6D A;  4IU9 A;  1HIJ A;  4EXP A;  3L5W I;  2CYK A;  4A3K D;  1GA3 A;  4TPJ A;  1YKB A;  1BP3 A;  3FKI D;  4WRL B;  4A3G D;  1M4C A;  4NKQ C;  2Q7N B;  5D70 A;  4A3E D;  4GRW A;  4NN7 A;  4W6V A;  1HUW A;  1F6F A;  1RFB A;  4GBY A;  4NN5 A;  1CYL A;  3PO3 D;  4BY1 D;  1AX8 A;  1Y6N L;  4ZS7 A;  5C4X D;  1EMR A;  5IYB D;  2XUT A;  1PW4 A;  1Z92 A;  4RS1 A;  3EW3 A;  1ITL A;  1CNT 1;  1I1R B;  4A3J D;  1LKI A;  3DGC L;  4D2C A;  5E4E A;  1Y14 A;  4A3M D;  4Z5R D;  3UEZ E;  3G9V B;  3HOV D;  5IP9 D;  3NCB A;  2O27 A;  1SCF A;  3HHR A;  3HMX B;  1HZI A;  1EER A;  3PIV A;  4ZF7 A;  2B8Y A;  1CSG A;  3EJJ A;  3PO2 D;  4A3I D;  3B5K A;  3LB6 B;  3PIW A;  4CNI C;  1BGC A;  1EKU A;  2Z3R A;  3I4M D;  5D6K A;  4IKY A;  1QVN A;  2B5I A;  4TPG A;  4JA3 A;  1PV7 A;  2B90 A;  3NCC A;  4X51 A;  3QB1 A;  4IKX A;  2V8N A;  4D2D A;  3QB7 A;  1ITI A;  1RCB A;  2JA8 D;  5D28 B;  5C65 A;  4NN6 A;  4A3D D;  5IYC D;  4ZW9 A;  1FYH A;  4O6K A;  5A2N A;  3UX9 A;  4DKE A;  3LB6 A;  2JA5 D;  4LEP A;  2XQB A;  3HOW D;  1BBN A;  2Z3Q A;  1KF9 A;  3D87 A;  1PVH B;  3BPL A;  2ILK A;  4BBR D;  4TPH A;  4Q65 A;  4ZWC A;  1ITF A;  1B5L A;  1F45 B;  3QT2 C;  1LQS L;  4A3B D;  3BPO A;  3NPZ A;  1Z7C A;  4A93 D;  4U4W A;  1HWG A;  1IL6 A;  1PW6 A;  3BES L;  3TGX B;  1VLK A;  2ERJ D;  1WCM D;  3HOU D;  3WCY I;  2D9Q A;  4I77 Z;  3N06 A;  2Y5Y A;  4YB9 D;  2OQP A;  4IKW A;  2KZ1 A;  1NBP A;  3DI2 A;  1HUL A;  4FA8 E;  4IKV A;  1HIK A;  1D9G A;  2B91 A;  2CFP A;  1CN4 C;  1M4R A;  4IU8 A;  2D48 A;  2JA6 D;  1M4A A;  4A3C D;  3HOY D;  4DKD A;  2L3O A;  4JR9 A;  1AU1 A;  1BGE A;  4A3F D;  3IRH A;  4YQX A;  4D2B A; 
#chains in the Genus database with same CATH homology
 3NCE A;  2Q98 A;  3QB7 A;  1ITI A;  1RCB A;  4BY7 D;  2GMF A;  1ETE A;  2B8U A;  3DLQ I;  2CYK A;  3L5W I;  4NEJ A;  5D28 B;  5C44 D;  4A3K D;  4NN6 A;  4NEM A;  4EXN A;  1GA3 A;  1LK3 A;  2B8X A;  4YPG C;  1BP3 A;  1Y6K L;  3FKI D;  4WRL B;  3OQ3 A;  4NI7 A;  4A3D D;  5IYC D;  4BBS D;  4A3G D;  1M4C A;  1M47 A;  4NKQ C;  1N1F A;  1IK0 A;  4BXX D;  1P9M B;  2Q7N B;  1JLI A;  1HWH A;  4PS4 A;  1FYH A;  4O6K A;  5D70 A;  2E9W C;  4MHL A;  4A3E D;  4GRW A;  1INR A;  3Q1S I;  4A3L D;  3D48 P;  1RHG A;  1EVS A;  1J7V L;  2C35 A;  3NCF A;  4NN7 A;  3UX9 A;  4DKE A;  3LB6 A;  1HUW A;  2JA5 D;  3H3V E;  2XQB A;  1F6F A;  1RFB A;  4NN5 A;  1CYL A;  2Q14 A;  3HOW D;  3SE3 B;  1BBN A;  2JA8 D;  5D71 A;  3PO3 D;  4BY1 D;  1AX8 A;  1M49 A;  2Z3Q A;  5KNH I;  1Y6N L;  2B63 D;  4DKF A;  3VA2 A;  3DUH C;  3HHC A;  1KF9 A;  3D87 A;  3S9D A;  4ZS7 A;  5C4X D;  1ILK A;  1AXI A;  5D22 A;  1EMR A;  5FLM D;  1PVH B;  3BPL A;  5IYB D;  2ILK A;  1Z92 A;  1BGD A;  4BBR D;  2HYM B;  3N0P A;  1V7N V;  1Y1V D;  4RS1 A;  3EW3 A;  1ITL A;  1IRL A;  2PSM A;  1IAR A;  1CNT 1;  2IL6 A;  1I1R B;  1B5L A;  1PGR A;  1F45 B;  4A3J D;  5TS9 A;  1ITF A;  1IJZ A;  5IYD D;  1LKI A;  1LQS L;  1M4B A;  3BPO A;  2INT A;  3OG6 A;  3QT2 C;  1PY2 A;  5D72 A;  4A3B D;  3H0G D;  3DGC L;  4YUE C;  3OG4 A;  1M48 A;  1Y6M L;  4YDY I;  3NPZ A;  3IRH A;  1Z7C A;  5E4E A;  2B8Z A;  5L6Y C;  4A93 D;  4YQX A;  1HWG A;  1IL6 A;  1ITM A;  2VUM D;  1PW6 A;  3BES L;  4DKC A;  2R92 D;  3TGX B;  1Y14 A;  4A3M D;  1VLK A;  4GS7 A;  3INK C;  2ERJ D;  3SE4 B;  1BUY A;  1WCM D;  4Z5R D;  3UEZ E;  3WCY I;  1D9C A;  1CD9 A;  2D9Q A;  3G9V B;  3NCB A;  5IP9 D;  3HOU D;  3HOV D;  3I4N D;  2O27 A;  4I77 Z;  1GNC A;  3N06 A;  1EXZ A;  1SCF A;  3HHR A;  3HMX B;  1HGU A;  1HZI A;  3AYH A;  1EER A;  2OQP A;  3QWR B;  1BCN A;  4NI9 A;  3PIV A;  1V7M V;  4ZF7 A;  2KZ1 A;  1NBP A;  5FUC A;  1RW5 A;  2H24 A;  5IP7 D;  3HOZ D;  2B8Y A;  3DI2 A;  1HUL A;  1CSG A;  2LMS A;  3UF5 A;  4DOH A;  4FA8 E;  1Y1W D;  5C3E D;  3MZG A;  3EJJ A;  1A22 A;  1HIK A;  1D9G A;  2B91 A;  3PO2 D;  4A3I D;  1CN4 C;  3B5K A;  1M4R A;  2R93 D;  3D85 C;  3L5X A;  2O26 A;  3LB6 B;  3PIW A;  4CNI C;  2JA7 D;  4O9H A;  2D48 A;  2O6I A;  2R7Z D;  1A7M A;  2LAG A;  5LQB A;  2JA6 D;  1BGC A;  1ALU A;  1M4A A;  4A3C D;  1EKU A;  3HOY D;  4DKD A;  2Z3R A;  3BPN A;  3I4M D;  3UF2 A;  5FHX A;  3HOX D;  1QVN A;  3DI3 A;  1FG9 A;  2B5I A;  4J4L C;  5C7X A;  3QAZ A;  1AU1 A;  1BGE A;  1WU3 I;  2B90 A;  3G6D A;  3NCC A;  4LRL A;  4X51 A;  2L3Y A;  2L3O A;  3QB1 A;  1HIJ A;  1YKB A;  4EXP A;  4A3F D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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