3HOYD

Complete rna polymerase ii elongation complex vi
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
218
structure length
178
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKETREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription,transferase/dna/rna hybrid
publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 49
structure length 178
sequence length 218
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3hoyD02
1Y1VD 3AYHA 4A93D 2B63D 4A3JD 5C4XD 5IP7D 4A3ED 3HOWD 2JA6D 2R7ZD 4A3CD 4BXXD 1Y1WD 3HOYD 4A3GD 5IYDD 1WCMD 4BY7D 3PO3D 5IP9D 2JA8D 3HOXD 2JA5D 3HOZD 4A3BD 4A3FD 3I4ND 2R92D 5C3ED 3FKID 3H3VE 4BY1D 5IYBD 3H0GD 2JA7D 4BBRD 5FLMD 4BBSD 4A3LD 1Y14A 3HOUD 3PO2D 4A3DD 4A3KD 3HOVD 2R93D 2VUMD 3I4MD 4A3ID 2C35A 5IYCD 4A3MD 5C44D
chains in the Genus database with same CATH superfamily
4NI9A 3QB7A 3DI3A 4A3CD 1N1FA 4A3GD 5IYDD 4IU8A 3Q1SI 4UVMA 3I4ND 3IRHA 3WCYI 3QB1A 2O27A 1M48A 4I77Z 3DGCL 2INTA 5D70A 3SE4B 5IYCD 5D6KA 3AYHA 2Q7NB 5A2NA 4DKEA 2KZ1A 1PY2A 3G9VB 1WCMD 5D59A 1ITIA 4TPJA 4IKZA 1M4AA 4ZWCA 1FG9A 4BY1D 5A2OA 1M4RA 1V7NV 1PV6A 1INRA 1HWGA 1M47A 1PV7A 3L5WI 2D48A 3DI2A 4D2CA 4TPGA 1ILKA 2B8ZA 2V8NA 1ALUA 4BY7D 4YUEC 3BPNA 4QIQA 4YBQA 3NCCA 3UF2A 1CSGA 5E4EA 1A7MA 3B5KA 3HHCA 2PSMA 1IL6A 1HUWA 1M49A 3HHRA 2B8YA 1ITFA 3O7QA 2Y5YA 2ILKA 1Y6NL 1BGCA 4W6VA 5GXBA 3G6DA 4RS1A 2XUTA 2VUMD 1Y6ML 5C44D 4IKYA 4LEPA 5C65A 3H3VE 4YQXA 5TS9A 5D22A 4GS7A 5FHXA 3HOVD 2C35A 4Q65A 3QWRB 1HULA 4D2DA 4Z5RD 2CFQA 1A22A 4MHLA 4EXNA 1PGRA 5EQHA 3H0GD 3BPOA 2O6IA 4BBRD 5FLMD 4A3KD 2R93D 1IK0A 4OAAA 1B5LA 1J7VL 2XQBA 2Q98A 3BPLA 1PW6A 4DOHA 1AXIA 2JA5D 4GC0A 4IKXA 4JA3A 1PW4A 4JR9A 1EKUA 5EQIA 2Q14A 4YPGC 1EERA 1AX8A 3D85C 1HIJA 1Y1VD 4NI7A 5L6YC 4WRLB 5IP9D 2JA8D 5LQBA 3S9DA 2O26A 3FKID 4CNIC 4YB9D 2GMFA 5EQGA 3LB6A 4U4VA 1BBNA 5D71A 3SE3B 1HZIA 4GBYA 2ERJD 2B8UA 3VA2A 1WU3I 1CYLA 4J05A 4DKCA 1D9GA 3UF5A 4ZS7A 4O9HA 3NCBA 4PS4A 3QAZA 4PYPA 1SCFA 3NPZA 3N0PA 2B63D 4A3ED 3HOWD 4X51A 3D87A 1VLKA 4A3FD 3OG4A 3MZGA 3PIWA 4NN5A 3NCFA 1NBPA 4XNIA 3I4MD 1FYHA 4NN6A 1M4CA 3WDOA 1JLIA 3O7PA 3PO3D 1HGUA 4NEMA 1HIKA 4NEJA 3NCEA 4ZF7A 4GRWA 3LB6B 5C3ED 3EJJA 3PO2D 2H24A 1BUYA 4A93D 4J4LC 2B8XA 4JREA 1QVNA 1BP3A 1Z7CA 3HOZD 2L3OA 3DUHC 5C7XA 2JA7D 3QT2C 2B91A 1RHGA 3HOUD 2D9QA 1PVHB 2E9WC 2Z3RA 4NN7A 1IRLA 4GBZA 4IU9A 5C4XD 3OQ3A 1LK3A 5D58A 1YKBA 1AU1A 4U4TA 4EXPA 2IL6A 3HMXB 4A3BD 1M4BA 1BGDA 2Z3QA 3BESL 1D9CA 5IYBD 1EMRA 4OH3A 1F6FA 3PIVA 1IARA 1RCBA 4LDSA 4NKQC 3UEZE 4A3DD 4IKWA 4ZYRA 2B5IA 1KF9A 3N06A 4FA8E 3DLQI 2L3YA 1GNCA 4TPHA 1LKIA 3EW3A 3HOYD 2LAGA 1CD9A 2R92D 2OQPA 1CNT1 5D72A 1F45B 4XNJA 3L5XA 4DKFA 4DKDA 4A3LD 4YDYI 1V7MV 2CFPA 1ITLA 1LQSL 1HWHA 4A3ID 2CYKA 1Z92A 1ITMA 4A3JD 2JA6D 1I1RB 1GA3A 1RFBA 1CN4C 4LRLA 1BGEA 2LMSA 2B90A 1Y6KL 4BBSD 3D48P 1Y14A 3OG6A 1EXZA 1P9MB 2HYMB 5IP7D 4BXXD 1Y1WD 1ETEA 5D28B 3TGXB 4O6KA 1RW5A 3HOXD 3INKC 4ZW9A 4ZWBA 5KNHI 3UX9A 4D2BA 4IKVA 5FUCA 4APSA 1IJZA 4U4WA 1BCNA 2R7ZD 1EVSA 4A3MD
chains in the Genus database with same CATH topology
1WU3I 4NI9A 5C44D 1CYLA 3QB7A 5C4XD 3OQ3A 1LK3A 3DI3A 4A3CD 1N1FA 1YKBA 4A3GD 5IYDD 1AU1A 4DKCA 1D9GA 3UF5A 3Q1SI 4EXPA 4ZS7A 2IL6A 3HMXB 4A3BD 1M4BA 1BGDA 2Z3QA 3I4ND 4O9HA 3BESL 3H3VE 3NCBA 1D9CA 4PS4A 5IYBD 4YQXA 1EMRA 1F6FA 3IRHA 5TS9A 5D22A 3PIVA 1IARA 3QB1A 2O27A 1M48A 1RCBA 4GS7A 3WCYI 4NKQC 4I77Z 3UEZE 3QAZA 5FHXA 4A3DD 3DGCL 1SCFA 3HOVD 2B5IA 1KF9A 3N06A 3NPZA 2INTA 5D70A 3SE4B 4FA8E 2C35A 5IYCD 3N0PA 3DLQI 3QWRB 2L3YA 3AYHA 1GNCA 2Q7NB 2B63D 4A3ED 3HOWD 4DKEA 1LKIA 2KZ1A 1PY2A 3EW3A 3G9VB 3HOYD 1HULA 2LAGA 1WCMD 4Z5RD 4X51A 1A22A 3D87A 4MHLA 1VLKA 1ITIA 4A3FD 1M4AA 4EXNA 1CD9A 1PGRA 3OG4A 2R92D 1FG9A 2OQPA 4BY1D 1CNT1 5D72A 1F45B 3H0GD 3BPOA 2O6IA 1M4RA 3L5XA 4BBRD 4DKFA 5FLMD 4DKDA 1V7NV 3MZGA 4A3LD 4YDYI 1V7MV 4A3KD 1ITLA 1LQSL 1INRA 3PIWA 1HWGA 1HWHA 4NN5A 2R93D 1M47A 3NCFA 1IK0A 1NBPA 3L5WI 4A3ID 3I4MD 2CYKA 1B5LA 1Z92A 1FYHA 2D48A 3DI2A 1J7VL 2XQBA 4NN6A 1M4CA 1ITMA 4A3JD 2Q98A 1ILKA 2JA6D 3BPLA 2B8ZA 1PW6A 1JLIA 4DOHA 1ALUA 4BY7D 1HGUA 4NEMA 1HIKA 4YUEC 1I1RB 3BPNA 4NEJA 3PO3D 1GA3A 1RFBA 3NCEA 1AXIA 2JA5D 3NCCA 3UF2A 1CSGA 5E4EA 4ZF7A 1CN4C 4GRWA 3LB6B 1BGEA 4LRLA 5C3ED 2LMSA 1A7MA 2B90A 3B5KA 3EJJA 3HHCA 1Y6KL 4BBSD 3D48P 1EKUA 1Y14A 3OG6A 3PO2D 2Q14A 1EXZA 4YPGC 2H24A 1EERA 1P9MB 1AX8A 2PSMA 3D85C 1HIJA 1IL6A 1Y1VD 1BUYA 4A93D 4J4LC 2HYMB 4NI7A 5IP7D 2B8XA 4BXXD 5L6YC 1Y1WD 1HUWA 1ETEA 1M49A 1QVNA 1BP3A 4WRLB 5D28B 1Z7CA 5IP9D 3HHRA 4O6KA 3TGXB 1RW5A 5LQBA 3HOXD 2JA8D 3INKC 2B8YA 3S9DA 3HOZD 1ITFA 2L3OA 2O26A 3FKID 2ILKA 4CNIC 5KNHI 1Y6NL 3UX9A 1BGCA 2GMFA 3DUHC 5C7XA 2JA7D 3LB6A 1BBNA 3QT2C 2B91A 1RHGA 5D71A 3HOUD 3SE3B 2D9QA 1PVHB 1HZIA 2E9WC 3G6DA 5FUCA 4RS1A 2VUMD 2Z3RA 1IJZA 2ERJD 2B8UA 4NN7A 1Y6ML 2R7ZD 3VA2A 1EVSA 1BCNA 4A3MD 1IRLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1V D;  3AYH A;  4A93 D;  2B63 D;  4A3J D;  5C4X D;  5IP7 D;  4A3E D;  3HOW D;  2JA6 D;  2R7Z D;  4A3C D;  4BXX D;  1Y1W D;  3HOY D;  4A3G D;  5IYD D;  1WCM D;  4BY7 D;  3PO3 D;  5IP9 D;  2JA8 D;  3HOX D;  2JA5 D;  3HOZ D;  4A3B D;  4A3F D;  3I4N D;  2R92 D;  5C3E D;  3FKI D;  3H3V E;  4BY1 D;  5IYB D;  3H0G D;  2JA7 D;  4BBR D;  5FLM D;  4BBS D;  4A3L D;  1Y14 A;  3HOU D;  3PO2 D;  4A3D D;  4A3K D;  3HOV D;  2R93 D;  2VUM D;  3I4M D;  4A3I D;  2C35 A;  5IYC D;  4A3M D;  5C44 D; 
#chains in the Genus database with same CATH topology
 4NI9 A;  3QB7 A;  3DI3 A;  4A3C D;  1N1F A;  4A3G D;  5IYD D;  4IU8 A;  3Q1S I;  4UVM A;  3I4N D;  3IRH A;  3WCY I;  3QB1 A;  2O27 A;  1M48 A;  4I77 Z;  3DGC L;  2INT A;  5D70 A;  3SE4 B;  5IYC D;  5D6K A;  3AYH A;  2Q7N B;  5A2N A;  4DKE A;  2KZ1 A;  1PY2 A;  3G9V B;  1WCM D;  5D59 A;  1ITI A;  4TPJ A;  4IKZ A;  1M4A A;  4ZWC A;  1FG9 A;  4BY1 D;  5A2O A;  1M4R A;  1V7N V;  1PV6 A;  1INR A;  1HWG A;  1M47 A;  1PV7 A;  3L5W I;  2D48 A;  3DI2 A;  4D2C A;  4TPG A;  1ILK A;  2B8Z A;  2V8N A;  1ALU A;  4BY7 D;  4YUE C;  3BPN A;  4QIQ A;  4YBQ A;  3NCC A;  3UF2 A;  1CSG A;  5E4E A;  1A7M A;  3B5K A;  3HHC A;  2PSM A;  1IL6 A;  1HUW A;  1M49 A;  3HHR A;  2B8Y A;  1ITF A;  3O7Q A;  2Y5Y A;  2ILK A;  1Y6N L;  1BGC A;  4W6V A;  5GXB A;  3G6D A;  4RS1 A;  2XUT A;  2VUM D;  1Y6M L;  5C44 D;  4IKY A;  4LEP A;  5C65 A;  3H3V E;  4YQX A;  5TS9 A;  5D22 A;  4GS7 A;  5FHX A;  3HOV D;  2C35 A;  4Q65 A;  3QWR B;  1HUL A;  4D2D A;  4Z5R D;  2CFQ A;  1A22 A;  4MHL A;  4EXN A;  1PGR A;  5EQH A;  3H0G D;  3BPO A;  2O6I A;  4BBR D;  5FLM D;  4A3K D;  2R93 D;  1IK0 A;  4OAA A;  1B5L A;  1J7V L;  2XQB A;  2Q98 A;  3BPL A;  1PW6 A;  4DOH A;  1AXI A;  2JA5 D;  4GC0 A;  4IKX A;  4JA3 A;  1PW4 A;  4JR9 A;  1EKU A;  5EQI A;  2Q14 A;  4YPG C;  1EER A;  1AX8 A;  3D85 C;  1HIJ A;  1Y1V D;  4NI7 A;  5L6Y C;  4WRL B;  5IP9 D;  2JA8 D;  5LQB A;  3S9D A;  2O26 A;  3FKI D;  4CNI C;  4YB9 D;  2GMF A;  5EQG A;  3LB6 A;  4U4V A;  1BBN A;  5D71 A;  3SE3 B;  1HZI A;  4GBY A;  2ERJ D;  2B8U A;  3VA2 A;  1WU3 I;  1CYL A;  4J05 A;  4DKC A;  1D9G A;  3UF5 A;  4ZS7 A;  4O9H A;  3NCB A;  4PS4 A;  3QAZ A;  4PYP A;  1SCF A;  3NPZ A;  3N0P A;  2B63 D;  4A3E D;  3HOW D;  4X51 A;  3D87 A;  1VLK A;  4A3F D;  3OG4 A;  3MZG A;  3PIW A;  4NN5 A;  3NCF A;  1NBP A;  4XNI A;  3I4M D;  1FYH A;  4NN6 A;  1M4C A;  3WDO A;  1JLI A;  3O7P A;  3PO3 D;  1HGU A;  4NEM A;  1HIK A;  4NEJ A;  3NCE A;  4ZF7 A;  4GRW A;  3LB6 B;  5C3E D;  3EJJ A;  3PO2 D;  2H24 A;  1BUY A;  4A93 D;  4J4L C;  2B8X A;  4JRE A;  1QVN A;  1BP3 A;  1Z7C A;  3HOZ D;  2L3O A;  3DUH C;  5C7X A;  2JA7 D;  3QT2 C;  2B91 A;  1RHG A;  3HOU D;  2D9Q A;  1PVH B;  2E9W C;  2Z3R A;  4NN7 A;  1IRL A;  4GBZ A;  4IU9 A;  5C4X D;  3OQ3 A;  1LK3 A;  5D58 A;  1YKB A;  1AU1 A;  4U4T A;  4EXP A;  2IL6 A;  3HMX B;  4A3B D;  1M4B A;  1BGD A;  2Z3Q A;  3BES L;  1D9C A;  5IYB D;  1EMR A;  4OH3 A;  1F6F A;  3PIV A;  1IAR A;  1RCB A;  4LDS A;  4NKQ C;  3UEZ E;  4A3D D;  4IKW A;  4ZYR A;  2B5I A;  1KF9 A;  3N06 A;  4FA8 E;  3DLQ I;  2L3Y A;  1GNC A;  4TPH A;  1LKI A;  3EW3 A;  3HOY D;  2LAG A;  1CD9 A;  2R92 D;  2OQP A;  1CNT 1;  5D72 A;  1F45 B;  4XNJ A;  3L5X A;  4DKF A;  4DKD A;  4A3L D;  4YDY I;  1V7M V;  2CFP A;  1ITL A;  1LQS L;  1HWH A;  4A3I D;  2CYK A;  1Z92 A;  1ITM A;  4A3J D;  2JA6 D;  1I1R B;  1GA3 A;  1RFB A;  1CN4 C;  4LRL A;  1BGE A;  2LMS A;  2B90 A;  1Y6K L;  4BBS D;  3D48 P;  1Y14 A;  3OG6 A;  1EXZ A;  1P9M B;  2HYM B;  5IP7 D;  4BXX D;  1Y1W D;  1ETE A;  5D28 B;  3TGX B;  4O6K A;  1RW5 A;  3HOX D;  3INK C;  4ZW9 A;  4ZWB A;  5KNH I;  3UX9 A;  4D2B A;  4IKV A;  5FUC A;  4APS A;  1IJZ A;  4U4W A;  1BCN A;  2R7Z D;  1EVS A;  4A3M D; 
#chains in the Genus database with same CATH homology
 1WU3 I;  4NI9 A;  5C44 D;  1CYL A;  3QB7 A;  5C4X D;  3OQ3 A;  1LK3 A;  3DI3 A;  4A3C D;  1N1F A;  1YKB A;  4A3G D;  5IYD D;  1AU1 A;  4DKC A;  1D9G A;  3UF5 A;  3Q1S I;  4EXP A;  4ZS7 A;  2IL6 A;  3HMX B;  4A3B D;  1M4B A;  1BGD A;  2Z3Q A;  3I4N D;  4O9H A;  3BES L;  3H3V E;  3NCB A;  1D9C A;  4PS4 A;  5IYB D;  4YQX A;  1EMR A;  1F6F A;  3IRH A;  5TS9 A;  5D22 A;  3PIV A;  1IAR A;  3QB1 A;  2O27 A;  1M48 A;  1RCB A;  4GS7 A;  3WCY I;  4NKQ C;  4I77 Z;  3UEZ E;  3QAZ A;  5FHX A;  4A3D D;  3DGC L;  1SCF A;  3HOV D;  2B5I A;  1KF9 A;  3N06 A;  3NPZ A;  2INT A;  5D70 A;  3SE4 B;  4FA8 E;  2C35 A;  5IYC D;  3N0P A;  3DLQ I;  3QWR B;  2L3Y A;  3AYH A;  1GNC A;  2Q7N B;  2B63 D;  4A3E D;  3HOW D;  4DKE A;  1LKI A;  2KZ1 A;  1PY2 A;  3EW3 A;  3G9V B;  3HOY D;  1HUL A;  2LAG A;  1WCM D;  4Z5R D;  4X51 A;  1A22 A;  3D87 A;  4MHL A;  1VLK A;  1ITI A;  4A3F D;  1M4A A;  4EXN A;  1CD9 A;  1PGR A;  3OG4 A;  2R92 D;  1FG9 A;  2OQP A;  4BY1 D;  1CNT 1;  5D72 A;  1F45 B;  3H0G D;  3BPO A;  2O6I A;  1M4R A;  3L5X A;  4BBR D;  4DKF A;  5FLM D;  4DKD A;  1V7N V;  3MZG A;  4A3L D;  4YDY I;  1V7M V;  4A3K D;  1ITL A;  1LQS L;  1INR A;  3PIW A;  1HWG A;  1HWH A;  4NN5 A;  2R93 D;  1M47 A;  3NCF A;  1IK0 A;  1NBP A;  3L5W I;  4A3I D;  3I4M D;  2CYK A;  1B5L A;  1Z92 A;  1FYH A;  2D48 A;  3DI2 A;  1J7V L;  2XQB A;  4NN6 A;  1M4C A;  1ITM A;  4A3J D;  2Q98 A;  1ILK A;  2JA6 D;  3BPL A;  2B8Z A;  1PW6 A;  1JLI A;  4DOH A;  1ALU A;  4BY7 D;  1HGU A;  4NEM A;  1HIK A;  4YUE C;  1I1R B;  3BPN A;  4NEJ A;  3PO3 D;  1GA3 A;  1RFB A;  3NCE A;  1AXI A;  2JA5 D;  3NCC A;  3UF2 A;  1CSG A;  5E4E A;  4ZF7 A;  1CN4 C;  4GRW A;  3LB6 B;  1BGE A;  4LRL A;  5C3E D;  2LMS A;  1A7M A;  2B90 A;  3B5K A;  3EJJ A;  3HHC A;  1Y6K L;  4BBS D;  3D48 P;  1EKU A;  1Y14 A;  3OG6 A;  3PO2 D;  2Q14 A;  1EXZ A;  4YPG C;  2H24 A;  1EER A;  1P9M B;  1AX8 A;  2PSM A;  3D85 C;  1HIJ A;  1IL6 A;  1Y1V D;  1BUY A;  4A93 D;  4J4L C;  2HYM B;  4NI7 A;  5IP7 D;  2B8X A;  4BXX D;  5L6Y C;  1Y1W D;  1HUW A;  1ETE A;  1M49 A;  1QVN A;  1BP3 A;  4WRL B;  5D28 B;  1Z7C A;  5IP9 D;  3HHR A;  4O6K A;  3TGX B;  1RW5 A;  5LQB A;  3HOX D;  2JA8 D;  3INK C;  2B8Y A;  3S9D A;  3HOZ D;  1ITF A;  2L3O A;  2O26 A;  3FKI D;  2ILK A;  4CNI C;  5KNH I;  1Y6N L;  3UX9 A;  1BGC A;  2GMF A;  3DUH C;  5C7X A;  2JA7 D;  3LB6 A;  1BBN A;  3QT2 C;  2B91 A;  1RHG A;  5D71 A;  3HOU D;  3SE3 B;  2D9Q A;  1PVH B;  1HZI A;  2E9W C;  3G6D A;  5FUC A;  4RS1 A;  2VUM D;  2Z3R A;  1IJZ A;  2ERJ D;  2B8U A;  4NN7 A;  1Y6M L;  2R7Z D;  3VA2 A;  1EVS A;  1BCN A;  4A3M D;  1IRL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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