3PO2D

Arrested rna polymerase ii elongation complex
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
221
structure length
180
Chain Sequence
MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of RNA polymerase II backtracking, arrest and reactivation.
pubmed doi rcsb
molecule tags Transferase/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 61
structure length 180
sequence length 221
ec nomenclature
pdb deposition date 2010-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3po2D02
4A3JD 3HOXD 2C35A 2VUMD 3HOVD 3AYHA 3PO2D 5C4XD 4A3MD 5IYBD 2R7ZD 4A3ID 2JA7D 3HOUD 5IP9D 3HOWD 4A3CD 2JA5D 3I4MD 2JA6D 3H0GD 5C3ED 4BY7D 2R92D 2JA8D 4A3ED 3H3VE 4A3KD 4BBRD 4BXXD 3HOYD 3HOZD 3I4ND 4A3GD 4A93D 4BBSD 3PO3D 4A3LD 2R93D 1Y1WD 3FKID 5FLMD 5IP7D 4A3DD 1Y1VD 1Y14A 5IYDD 5C44D 4A3BD 4A3FD 1WCMD 5IYCD 2B63D 4BY1D
chains in the Genus database with same CATH superfamily
4NI9A 1LKIA 4UVMA 5D22A 1F6FA 4NI7A 1BUYA 4JA3A 2JA6D 2R92D 3H3VE 3D85C 1Y1WD 1Y1VD 1HULA 2B91A 3N06A 5C65A 2CYKA 3TGXB 1EERA 4I77Z 2C35A 2XUTA 5IP9D 2JA5D 1AU1A 1CNT1 1RW5A 5D28B 5FHXA 5KNHI 1NBPA 1J7VL 2O26A 3WCYI 4BY1D 4QIQA 1M4AA 1HGUA 1PVHB 3AYHA 1IL6A 3DLQI 4O9HA 1ALUA 4DKCA 2JA8D 5D58A 4Z5RD 2GMFA 3OQ3A 3D48P 4TPJA 1EVSA 5EQIA 4IU9A 4A3FD 1GA3A 1D9GA 5D70A 2LMSA 3IRHA 2L3YA 1A22A 1CD9A 2Q7NB 4NN5A 3HOVD 4U4VA 1CSGA 2ILKA 3DI3A 4BY7D 2LAGA 4APSA 4GBYA 2O27A 5FLMD 5D71A 1Y6ML 1M48A 5C7XA 3OG4A 4X51A 1QVNA 3Q1SI 1VLKA 2CFQA 4A3ID 2JA7D 3EJJA 2B8YA 4NEJA 4J4LC 4D2CA 4GRWA 5D72A 3UF5A 2D9QA 2B8ZA 3L5WI 1Y6KL 5IYCD 3UF2A 1PW4A 4NKQC 2R7ZD 1CN4C 4XNIA 1BCNA 1HIKA 4YBQA 2E9WC 4IKZA 4A93D 5D6KA 3UEZE 1IJZA 2B5IA 5EQGA 3LB6A 3BESL 3NCBA 4YB9D 1BGDA 1PGRA 4U4TA 1IARA 3O7PA 5C3ED 1KF9A 1EKUA 1HUWA 1HWGA 2R93D 1A7MA 1LK3A 4IKXA 4DKEA 3B5KA 1PV7A 4LDSA 4MHLA 2V8NA 1ITMA 4A3JD 2HYMB 3WDOA 1WU3I 1HZIA 1FYHA 4WRLB 4TPHA 4OH3A 2B8UA 4ZWBA 3HHCA 4D2DA 4NN6A 3NCCA 5IYDD 1Y14A 2B63D 5A2NA 1Z7CA 4FA8E 3PO2D 3G6DA 4A3MD 5IYBD 1ITIA 4IKWA 2INTA 4OAAA 1JLIA 3NCFA 1SCFA 1RFBA 2O6IA 1RCBA 1CYLA 3I4ND 4A3GD 3SE3B 1ITLA 3NPZA 3NCEA 2H24A 1RHGA 2Z3QA 3DUHC 4D2BA 4A3CD 3HOUD 1EMRA 3I4MD 4DKDA 3PIWA 3MZGA 1V7NV 5C44D 1INRA 2PSMA 2IL6A 2OQPA 4DOHA 3HMXB 4J05A 1B5LA 4XNJA 1EXZA 4JR9A 3INKC 3SE4B 3HOWD 5EQHA 3UX9A 2ERJD 3H0GD 5LQBA 4GBZA 1PY2A 2B90A 4BXXD 4U4WA 3O7QA 2XQBA 4NN7A 4W6VA 2CFPA 3FKID 5IP7D 3N0PA 3S9DA 3HOXD 4YDYI 3VA2A 3BPLA 4TPGA 1LQSL 1N1FA 4IKYA 4JREA 3G9VB 1ITFA 4ZWCA 2B8XA 4IU8A 1GNCA 3HOZD 4ZW9A 3DI2A 3PO3D 3DGCL 3D87A 3QB1A 4DKFA 5D59A 1BGEA 2Q14A 4IKVA 1HWHA 1V7MV 1D9CA 1ETEA 2Z3RA 1BGCA 3QB7A 1Y6NL 5L6YC 4NEMA 4ZYRA 4A3LD 5A2OA 4GS7A 4Q65A 2D48A 1M4RA 1PW6A 4YPGC 5TS9A 3LB6B 2L3OA 1M4CA 4LEPA 3HOYD 4EXNA 1I1RB 4BBSD 4A3DD 1IK0A 4A3BD 1PV6A 1M47A 4PS4A 4O6KA 4YUEC 3QWRB 4RS1A 1AX8A 1M49A 2VUMD 1FG9A 5C4XD 1IRLA 5GXBA 5FUCA 1YKBA 3BPNA 4A3KD 3QT2C 4YQXA 1BP3A 1F45B 1ILKA 4GC0A 1HIJA 5E4EA 1WCMD 4LRLA 3EW3A 3BPOA 3L5XA 3HHRA 4ZS7A 1BBNA 2Q98A 4CNIC 4ZF7A 3PIVA 1Z92A 2Y5YA 3OG6A 4A3ED 4EXPA 4BBRD 1AXIA 1M4BA 3QAZA 2KZ1A 1P9MB 4PYPA
chains in the Genus database with same CATH topology
1D9CA 1ETEA 1Z7CA 4X51A 1QVNA 2Z3RA 3Q1SI 1BGCA 4NI9A 4FA8E 1LKIA 1VLKA 3PO2D 3G6DA 4A3MD 3QB7A 5IYBD 4A3ID 2INTA 5D22A 2JA7D 1ITIA 1JLIA 1F6FA 4NI7A 3NCFA 3EJJA 2B8YA 1Y6NL 1BUYA 5L6YC 4NEJA 1SCFA 1RFBA 4J4LC 2JA6D 2O6IA 1RCBA 2R92D 4NEMA 3H3VE 3D85C 1CYLA 3I4ND 4GRWA 5D72A 4A3GD 4A3LD 3SE3B 4GS7A 1Y1WD 1ITLA 2D48A 3NPZA 3UF5A 3NCEA 2H24A 2D9QA 1Y1VD 2B8ZA 3L5WI 1Y6KL 1HULA 1RHGA 5IYCD 2B91A 3UF2A 2Z3QA 3N06A 2CYKA 3DUHC 3TGXB 1EERA 4I77Z 2C35A 1M4RA 4NKQC 2R7ZD 4A3CD 3HOUD 1PW6A 5IP9D 1CN4C 1EMRA 1BCNA 4YPGC 5TS9A 2JA5D 3I4MD 1HIKA 4DKDA 1AU1A 1CNT1 1RW5A 3LB6B 3PIWA 2L3OA 2E9WC 1M4CA 3HOYD 3MZGA 5D28B 4EXNA 5FHXA 1I1RB 4A3JD 4BBSD 4A93D 5KNHI 3UEZE 1IJZA 4A3DD 1NBPA 1J7VL 1V7NV 2O26A 5C44D 4A3BD 1IK0A 1M47A 1INRA 3WCYI 2B5IA 4O6KA 2PSMA 2IL6A 4PS4A 2OQPA 4YUEC 4DOHA 3LB6A 4BY1D 3BESL 3HMXB 1M4AA 3QWRB 1B5LA 1AX8A 4RS1A 1HGUA 1EXZA 1M49A 1PVHB 3NCBA 2VUMD 3AYHA 1FG9A 3INKC 3SE4B 5C4XD 3HOWD 1IL6A 3UX9A 2ERJD 1BGDA 1IRLA 3DLQI 1PGRA 4O9HA 5FUCA 1YKBA 1IARA 3H0GD 1ALUA 5C3ED 4DKCA 1KF9A 5LQBA 2JA8D 3BPNA 1PY2A 1EKUA 2B90A 4A3KD 4Z5RD 4BXXD 1HUWA 3QT2C 2GMFA 3OQ3A 3D48P 4YQXA 1HWGA 1BP3A 2XQBA 4NN7A 2R93D 1EVSA 1A7MA 3FKID 1LK3A 5IP7D 1F45B 3N0PA 1HWHA 1ILKA 1HIJA 4A3FD 1GA3A 1D9GA 4DKEA 1WCMD 3B5KA 4MHLA 5D70A 2LMSA 4LRLA 3IRHA 2L3YA 5E4EA 1ITMA 3BPOA 3EW3A 1A22A 2HYMB 4YDYI 3S9DA 1CD9A 3VA2A 3HOXD 3BPLA 3L5XA 4NN5A 2Q7NB 1WU3I 3HOVD 1LQSL 3HHRA 4ZS7A 1N1FA 1HZIA 1BBNA 2Q98A 1FYHA 1CSGA 4CNIC 2ILKA 3DI3A 4ZF7A 3G9VB 1ITFA 4WRLB 2B8XA 1Z92A 3PIVA 2B8UA 4BY7D 2LAGA 3OG6A 4A3ED 4EXPA 4BBRD 1GNCA 1AXIA 1M4BA 3HOZD 3HHCA 3DI2A 3PO3D 3DGCL 4NN6A 3QAZA 3NCCA 2KZ1A 2O27A 3D87A 3QB1A 4DKFA 5FLMD 5D71A 5IYDD 1Y14A 1Y6ML 1P9MB 1BGEA 1M48A 2Q14A 5C7XA 2B63D 3OG4A 1V7MV
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3J D;  3HOX D;  2C35 A;  2VUM D;  3HOV D;  3AYH A;  3PO2 D;  5C4X D;  4A3M D;  5IYB D;  2R7Z D;  4A3I D;  2JA7 D;  3HOU D;  5IP9 D;  3HOW D;  4A3C D;  2JA5 D;  3I4M D;  2JA6 D;  3H0G D;  5C3E D;  4BY7 D;  2R92 D;  2JA8 D;  4A3E D;  3H3V E;  4A3K D;  4BBR D;  4BXX D;  3HOY D;  3HOZ D;  3I4N D;  4A3G D;  4A93 D;  4BBS D;  3PO3 D;  4A3L D;  2R93 D;  1Y1W D;  3FKI D;  5FLM D;  5IP7 D;  4A3D D;  1Y1V D;  1Y14 A;  5IYD D;  5C44 D;  4A3B D;  4A3F D;  1WCM D;  5IYC D;  2B63 D;  4BY1 D; 
#chains in the Genus database with same CATH topology
 4NI9 A;  1LKI A;  4UVM A;  5D22 A;  1F6F A;  4NI7 A;  1BUY A;  4JA3 A;  2JA6 D;  2R92 D;  3H3V E;  3D85 C;  1Y1W D;  1Y1V D;  1HUL A;  2B91 A;  3N06 A;  5C65 A;  2CYK A;  3TGX B;  1EER A;  4I77 Z;  2C35 A;  2XUT A;  5IP9 D;  2JA5 D;  1AU1 A;  1CNT 1;  1RW5 A;  5D28 B;  5FHX A;  5KNH I;  1NBP A;  1J7V L;  2O26 A;  3WCY I;  4BY1 D;  4QIQ A;  1M4A A;  1HGU A;  1PVH B;  3AYH A;  1IL6 A;  3DLQ I;  4O9H A;  1ALU A;  4DKC A;  2JA8 D;  5D58 A;  4Z5R D;  2GMF A;  3OQ3 A;  3D48 P;  4TPJ A;  1EVS A;  5EQI A;  4IU9 A;  4A3F D;  1GA3 A;  1D9G A;  5D70 A;  2LMS A;  3IRH A;  2L3Y A;  1A22 A;  1CD9 A;  2Q7N B;  4NN5 A;  3HOV D;  4U4V A;  1CSG A;  2ILK A;  3DI3 A;  4BY7 D;  2LAG A;  4APS A;  4GBY A;  2O27 A;  5FLM D;  5D71 A;  1Y6M L;  1M48 A;  5C7X A;  3OG4 A;  4X51 A;  1QVN A;  3Q1S I;  1VLK A;  2CFQ A;  4A3I D;  2JA7 D;  3EJJ A;  2B8Y A;  4NEJ A;  4J4L C;  4D2C A;  4GRW A;  5D72 A;  3UF5 A;  2D9Q A;  2B8Z A;  3L5W I;  1Y6K L;  5IYC D;  3UF2 A;  1PW4 A;  4NKQ C;  2R7Z D;  1CN4 C;  4XNI A;  1BCN A;  1HIK A;  4YBQ A;  2E9W C;  4IKZ A;  4A93 D;  5D6K A;  3UEZ E;  1IJZ A;  2B5I A;  5EQG A;  3LB6 A;  3BES L;  3NCB A;  4YB9 D;  1BGD A;  1PGR A;  4U4T A;  1IAR A;  3O7P A;  5C3E D;  1KF9 A;  1EKU A;  1HUW A;  1HWG A;  2R93 D;  1A7M A;  1LK3 A;  4IKX A;  4DKE A;  3B5K A;  1PV7 A;  4LDS A;  4MHL A;  2V8N A;  1ITM A;  4A3J D;  2HYM B;  3WDO A;  1WU3 I;  1HZI A;  1FYH A;  4WRL B;  4TPH A;  4OH3 A;  2B8U A;  4ZWB A;  3HHC A;  4D2D A;  4NN6 A;  3NCC A;  5IYD D;  1Y14 A;  2B63 D;  5A2N A;  1Z7C A;  4FA8 E;  3PO2 D;  3G6D A;  4A3M D;  5IYB D;  1ITI A;  4IKW A;  2INT A;  4OAA A;  1JLI A;  3NCF A;  1SCF A;  1RFB A;  2O6I A;  1RCB A;  1CYL A;  3I4N D;  4A3G D;  3SE3 B;  1ITL A;  3NPZ A;  3NCE A;  2H24 A;  1RHG A;  2Z3Q A;  3DUH C;  4D2B A;  4A3C D;  3HOU D;  1EMR A;  3I4M D;  4DKD A;  3PIW A;  3MZG A;  1V7N V;  5C44 D;  1INR A;  2PSM A;  2IL6 A;  2OQP A;  4DOH A;  3HMX B;  4J05 A;  1B5L A;  4XNJ A;  1EXZ A;  4JR9 A;  3INK C;  3SE4 B;  3HOW D;  5EQH A;  3UX9 A;  2ERJ D;  3H0G D;  5LQB A;  4GBZ A;  1PY2 A;  2B90 A;  4BXX D;  4U4W A;  3O7Q A;  2XQB A;  4NN7 A;  4W6V A;  2CFP A;  3FKI D;  5IP7 D;  3N0P A;  3S9D A;  3HOX D;  4YDY I;  3VA2 A;  3BPL A;  4TPG A;  1LQS L;  1N1F A;  4IKY A;  4JRE A;  3G9V B;  1ITF A;  4ZWC A;  2B8X A;  4IU8 A;  1GNC A;  3HOZ D;  4ZW9 A;  3DI2 A;  3PO3 D;  3DGC L;  3D87 A;  3QB1 A;  4DKF A;  5D59 A;  1BGE A;  2Q14 A;  4IKV A;  1HWH A;  1V7M V;  1D9C A;  1ETE A;  2Z3R A;  1BGC A;  3QB7 A;  1Y6N L;  5L6Y C;  4NEM A;  4ZYR A;  4A3L D;  5A2O A;  4GS7 A;  4Q65 A;  2D48 A;  1M4R A;  1PW6 A;  4YPG C;  5TS9 A;  3LB6 B;  2L3O A;  1M4C A;  4LEP A;  3HOY D;  4EXN A;  1I1R B;  4BBS D;  4A3D D;  1IK0 A;  4A3B D;  1PV6 A;  1M47 A;  4PS4 A;  4O6K A;  4YUE C;  3QWR B;  4RS1 A;  1AX8 A;  1M49 A;  2VUM D;  1FG9 A;  5C4X D;  1IRL A;  5GXB A;  5FUC A;  1YKB A;  3BPN A;  4A3K D;  3QT2 C;  4YQX A;  1BP3 A;  1F45 B;  1ILK A;  4GC0 A;  1HIJ A;  5E4E A;  1WCM D;  4LRL A;  3EW3 A;  3BPO A;  3L5X A;  3HHR A;  4ZS7 A;  1BBN A;  2Q98 A;  4CNI C;  4ZF7 A;  3PIV A;  1Z92 A;  2Y5Y A;  3OG6 A;  4A3E D;  4EXP A;  4BBR D;  1AXI A;  1M4B A;  3QAZ A;  2KZ1 A;  1P9M B;  4PYP A; 
#chains in the Genus database with same CATH homology
 1D9C A;  1ETE A;  1Z7C A;  4X51 A;  1QVN A;  2Z3R A;  3Q1S I;  1BGC A;  4NI9 A;  4FA8 E;  1LKI A;  1VLK A;  3PO2 D;  3G6D A;  4A3M D;  3QB7 A;  5IYB D;  4A3I D;  2INT A;  5D22 A;  2JA7 D;  1ITI A;  1JLI A;  1F6F A;  4NI7 A;  3NCF A;  3EJJ A;  2B8Y A;  1Y6N L;  1BUY A;  5L6Y C;  4NEJ A;  1SCF A;  1RFB A;  4J4L C;  2JA6 D;  2O6I A;  1RCB A;  2R92 D;  4NEM A;  3H3V E;  3D85 C;  1CYL A;  3I4N D;  4GRW A;  5D72 A;  4A3G D;  4A3L D;  3SE3 B;  4GS7 A;  1Y1W D;  1ITL A;  2D48 A;  3NPZ A;  3UF5 A;  3NCE A;  2H24 A;  2D9Q A;  1Y1V D;  2B8Z A;  3L5W I;  1Y6K L;  1HUL A;  1RHG A;  5IYC D;  2B91 A;  3UF2 A;  2Z3Q A;  3N06 A;  2CYK A;  3DUH C;  3TGX B;  1EER A;  4I77 Z;  2C35 A;  1M4R A;  4NKQ C;  2R7Z D;  4A3C D;  3HOU D;  1PW6 A;  5IP9 D;  1CN4 C;  1EMR A;  1BCN A;  4YPG C;  5TS9 A;  2JA5 D;  3I4M D;  1HIK A;  4DKD A;  1AU1 A;  1CNT 1;  1RW5 A;  3LB6 B;  3PIW A;  2L3O A;  2E9W C;  1M4C A;  3HOY D;  3MZG A;  5D28 B;  4EXN A;  5FHX A;  1I1R B;  4A3J D;  4BBS D;  4A93 D;  5KNH I;  3UEZ E;  1IJZ A;  4A3D D;  1NBP A;  1J7V L;  1V7N V;  2O26 A;  5C44 D;  4A3B D;  1IK0 A;  1M47 A;  1INR A;  3WCY I;  2B5I A;  4O6K A;  2PSM A;  2IL6 A;  4PS4 A;  2OQP A;  4YUE C;  4DOH A;  3LB6 A;  4BY1 D;  3BES L;  3HMX B;  1M4A A;  3QWR B;  1B5L A;  1AX8 A;  4RS1 A;  1HGU A;  1EXZ A;  1M49 A;  1PVH B;  3NCB A;  2VUM D;  3AYH A;  1FG9 A;  3INK C;  3SE4 B;  5C4X D;  3HOW D;  1IL6 A;  3UX9 A;  2ERJ D;  1BGD A;  1IRL A;  3DLQ I;  1PGR A;  4O9H A;  5FUC A;  1YKB A;  1IAR A;  3H0G D;  1ALU A;  5C3E D;  4DKC A;  1KF9 A;  5LQB A;  2JA8 D;  3BPN A;  1PY2 A;  1EKU A;  2B90 A;  4A3K D;  4Z5R D;  4BXX D;  1HUW A;  3QT2 C;  2GMF A;  3OQ3 A;  3D48 P;  4YQX A;  1HWG A;  1BP3 A;  2XQB A;  4NN7 A;  2R93 D;  1EVS A;  1A7M A;  3FKI D;  1LK3 A;  5IP7 D;  1F45 B;  3N0P A;  1HWH A;  1ILK A;  1HIJ A;  4A3F D;  1GA3 A;  1D9G A;  4DKE A;  1WCM D;  3B5K A;  4MHL A;  5D70 A;  2LMS A;  4LRL A;  3IRH A;  2L3Y A;  5E4E A;  1ITM A;  3BPO A;  3EW3 A;  1A22 A;  2HYM B;  4YDY I;  3S9D A;  1CD9 A;  3VA2 A;  3HOX D;  3BPL A;  3L5X A;  4NN5 A;  2Q7N B;  1WU3 I;  3HOV D;  1LQS L;  3HHR A;  4ZS7 A;  1N1F A;  1HZI A;  1BBN A;  2Q98 A;  1FYH A;  1CSG A;  4CNI C;  2ILK A;  3DI3 A;  4ZF7 A;  3G9V B;  1ITF A;  4WRL B;  2B8X A;  1Z92 A;  3PIV A;  2B8U A;  4BY7 D;  2LAG A;  3OG6 A;  4A3E D;  4EXP A;  4BBR D;  1GNC A;  1AXI A;  1M4B A;  3HOZ D;  3HHC A;  3DI2 A;  3PO3 D;  3DGC L;  4NN6 A;  3QAZ A;  3NCC A;  2KZ1 A;  2O27 A;  3D87 A;  3QB1 A;  4DKF A;  5FLM D;  5D71 A;  5IYD D;  1Y14 A;  1Y6M L;  1P9M B;  1BGE A;  1M48 A;  2Q14 A;  5C7X A;  2B63 D;  3OG4 A;  1V7M V; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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