3PO3D

Arrested rna polymerase ii reactivation intermediate
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
218
structure length
177
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/dna/rna
source organism Saccharomyces cerevisiae
publication title Structural basis of RNA polymerase II backtracking, arrest and reactivation.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 53
structure length 177
sequence length 218
ec nomenclature
pdb deposition date 2010-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3po3D02
4BBSD 3AYHA 5C44D 3HOWD 5IYBD 4A3JD 4A3LD 1Y14A 2R92D 4BBRD 3FKID 5IYCD 4A3ED 2R7ZD 2C35A 5C4XD 5IYDD 3HOXD 2JA7D 4A3ID 3I4ND 4A93D 2VUMD 2JA5D 5IP9D 5FLMD 2JA6D 4A3CD 3HOVD 5C3ED 2R93D 4BY1D 2JA8D 1Y1WD 4A3BD 1Y1VD 3H0GD 3HOUD 3PO3D 5IP7D 4A3GD 4A3DD 3I4MD 3HOYD 4A3FD 3H3VE 3HOZD 1WCMD 2B63D 4BXXD 4BY7D 4A3MD 4A3KD 3PO2D
chains in the Genus database with same CATH superfamily
2LAGA 3AYHA 5C44D 1EMRA 4IKZA 1KF9A 5D58A 3G6DA 3DGCL 1RCBA 1AX8A 5IYCD 4NI7A 5D6KA 2JA5D 4NN6A 4JA3A 3HHCA 4A3BD 1WCMD 1A7MA 3UX9A 4D2CA 3O7PA 1HIKA 2O6IA 4MHLA 2CYKA 4GRWA 1ETEA 1HGUA 2D48A 1B5LA 3HOVD 1HWGA 1ILKA 1LK3A 4Z5RD 2B5IA 1A22A 4I77Z 1WU3I 1HIJA 3HMXB 4NN7A 4Q65A 1BP3A 5IYDD 1P9MB 3BESL 2LMSA 3MZGA 1M4BA 1RFBA 2HYMB 1NBPA 2B8ZA 4GBYA 1Y6KL 4CNIC 2Q98A 3QAZA 5L6YC 3WCYI 1F45B 1GA3A 5FHXA 3Q1SI 3OG6A 4OH3A 4ZWCA 3L5XA 4A3JD 1VLKA 3NCFA 1I1RB 2O27A 3EJJA 4O6KA 3HOXD 4QIQA 2ERJD 4ZS7A 3I4ND 2B90A 1GNCA 1Y6NL 4DKFA 1ITIA 4YUEC 2KZ1A 1M4CA 3SE3B 4A3GD 1ITLA 4NKQC 1D9CA 1FG9A 4BY7D 4U4VA 4A3KD 3TGXB 5EQHA 3D85C 5FUCA 2CFPA 3BPLA 5E4EA 4NEMA 2VUMD 4D2BA 2R93D 1PW4A 2JA8D 3BPOA 3LB6B 4PS4A 3I4MD 2B63D 5TS9A 4TPJA 5C65A 4IU8A 4ZWBA 4LEPA 3G9VB 5C4XD 4LRLA 4NI9A 3DI3A 4IKVA 1ITFA 4GC0A 1JLIA 4W6VA 4BY1D 4UVMA 5IP7D 2B8UA 1BGCA 4ZF7A 4U4WA 4D2DA 4BBSD 1CN4C 3UF2A 5D72A 4XNIA 1IARA 1ALUA 3NCEA 5FLMD 4FA8E 3N0PA 5C3ED 1BBNA 3H3VE 2L3YA 4U4TA 2B91A 3S9DA 3L5WI 4A3MD 2O26A 4DOHA 3HOWD 5EQGA 3D87A 2B8XA 4TPGA 4GS7A 3O7QA 1HWHA 5D22A 1AXIA 3NCCA 2OQPA 2JA6D 1PV6A 4IKXA 1CYLA 3BPNA 4EXNA 4NEJA 4X51A 5D59A 3DI2A 3EW3A 3PO2D 4A3LD 3QB1A 4OAAA 3DLQI 1IK0A 3B5KA 1J7VL 2D9QA 3SE4B 4DKCA 4A3ID 1IRLA 3IRHA 1QVNA 3H0GD 4A3DD 3HOZD 1M49A 1D9GA 1F6FA 4XNJA 5D28B 5D71A 1CD9A 1AU1A 1Z7CA 1N1FA 4YDYI 2Z3RA 1EERA 1RW5A 4J05A 1IJZA 3WDOA 1PGRA 3HOUD 4O9HA 4A3FD 4BXXD 2ILKA 3PIVA 3INKC 4APSA 2Y5YA 4J4LC 3UF5A 4ZYRA 2V8NA 4JR9A 4IKYA 1BGEA 3QT2C 3D48P 1EXZA 5LQBA 4IU9A 3PO3D 5A2OA 4NN5A 1YKBA 4LDSA 4DKEA 4YPGC 4ZW9A 2Q7NB 5A2NA 4A3ED 4PYPA 2B8YA 4YB9D 4EXPA 1CSGA 2GMFA 1HULA 3OQ3A 3HHRA 1M48A 1PW6A 4GBZA 4DKDA 1ITMA 3QWRB 1V7NV 4BBRD 2Q14A 1LQSL 3NCBA 2R7ZD 2C35A 5C7XA 5IP9D 4A3CD 1Y1WD 2H24A 1M4RA 2E9WC 3UEZE 1RHGA 1M47A 1V7MV 1PV7A 1Y14A 2XQBA 5D70A 2R92D 4IKWA 1Z92A 1CNT1 2L3OA 4WRLB 1EKUA 1LKIA 2PSMA 4YQXA 1Y6ML 3VA2A 1HZIA 5EQIA 4RS1A 3PIWA 3LB6A 4YBQA 2INTA 1BUYA 4JREA 1BCNA 1PY2A 2IL6A 2JA7D 1PVHB 3QB7A 4A93D 3OG4A 1BGDA 1INRA 5KNHI 1IL6A 1FYHA 5IYBD 5GXBA 3N06A 3NPZA 3FKID 2Z3QA 1SCFA 1EVSA 4TPHA 2CFQA 2XUTA 1Y1VD 1HUWA 3HOYD 1M4AA 3DUHC
chains in the Genus database with same CATH topology
2LAGA 3AYHA 4DKDA 1ITMA 1EMRA 5C44D 1KF9A 3D85C 3QWRB 4A3LD 3G6DA 3DGCL 1V7NV 3QB1A 4BBRD 2Q14A 1RCBA 5FUCA 3DLQI 1LQSL 1IK0A 1AX8A 3NCBA 5IYCD 3B5KA 2C35A 4NI7A 1J7VL 2D9QA 3SE4B 5C7XA 2R7ZD 4DKCA 3BPLA 4A3ID 1IRLA 5E4EA 4NEMA 2JA5D 2VUMD 4NN6A 5IP9D 4A3CD 3IRHA 2R93D 2JA8D 3BPOA 1Y1WD 1QVNA 1M4RA 2H24A 3HHCA 3H0GD 3LB6B 4PS4A 2E9WC 4A3BD 4A3DD 3I4MD 3HOZD 1M49A 3UEZE 1WCMD 2B63D 5TS9A 1RHGA 1D9GA 1F6FA 1M47A 3UX9A 1A7MA 1V7MV 5D28B 1Y14A 2XQBA 5D70A 5D71A 2R92D 3G9VB 1CD9A 1AU1A 1Z7CA 3QT2C 1N1FA 5C4XD 4LRLA 1HIKA 4YDYI 2O6IA 1EERA 2Z3RA 4NI9A 4MHLA 1Z92A 1CNT1 1RW5A 2CYKA 1ETEA 3DI3A 1HGUA 4GRWA 2D48A 1IJZA 2L3OA 1ITFA 4WRLB 1B5LA 1EKUA 1JLIA 3HOVD 1PGRA 4BY1D 3HOUD 1HWGA 1LKIA 1ILKA 2B8UA 4O9HA 2PSMA 5IP7D 4A3FD 4YQXA 1Y6ML 3VA2A 1HZIA 1LK3A 4Z5RD 4RS1A 2B5IA 1BGCA 1A22A 4I77Z 2ILKA 4ZF7A 4BXXD 3PIVA 3PIWA 3LB6A 1WU3I 1HIJA 4BBSD 1CN4C 3HMXB 2INTA 3INKC 4NN7A 1BUYA 4J4LC 3UF5A 1BCNA 1PY2A 2IL6A 3UF2A 5D72A 1BGEA 1IARA 1ALUA 1BP3A 3D48P 1P9MB 3BESL 1EXZA 1PVHB 2LMSA 3QB7A 5IYDD 3MZGA 1M4BA 2JA7D 5LQBA 1RFBA 3OG4A 2HYMB 1NBPA 4A93D 3NCEA 1BGDA 5FLMD 2B8ZA 3N0PA 4FA8E 5C3ED 1Y6KL 1INRA 1BBNA 4CNIC 2Q98A 3PO3D 4NN5A 3QAZA 3H3VE 2L3YA 5L6YC 3WCYI 1YKBA 2B91A 4DKEA 1F45B 1GA3A 5FHXA 3S9DA 5KNHI 1IL6A 1FYHA 3L5WI 3Q1SI 3OG6A 4YPGC 2Q7NB 2O26A 4A3MD 4DOHA 3HOWD 3D87A 2B8XA 3L5XA 5IYBD 1VLKA 4A3JD 3NCFA 3N06A 3NPZA 3FKID 4GS7A 1I1RB 2O27A 3EJJA 4A3ED 2Z3QA 1HWHA 4O6KA 5D22A 3HOXD 1SCFA 2ERJD 1AXIA 1EVSA 2B8YA 4ZS7A 3NCCA 3I4ND 2B90A 1GNCA 1Y6NL 2OQPA 4DKFA 4EXPA 2JA6D 1ITIA 1CSGA 2GMFA 4YUEC 2KZ1A 1CYLA 1HULA 1M4CA 3OQ3A 3HHRA 1Y1VD 1M48A 3SE3B 4A3GD 1HUWA 1ITLA 3HOYD 1PW6A 4NKQC 3BPNA 1M4AA 1D9CA 1FG9A 4EXNA 4NEJA 4X51A 3DI2A 3DUHC 3EW3A 4BY7D 4A3KD 3TGXB 3PO2D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BBS D;  3AYH A;  5C44 D;  3HOW D;  5IYB D;  4A3J D;  4A3L D;  1Y14 A;  2R92 D;  4BBR D;  3FKI D;  5IYC D;  4A3E D;  2R7Z D;  2C35 A;  5C4X D;  5IYD D;  3HOX D;  2JA7 D;  4A3I D;  3I4N D;  4A93 D;  2VUM D;  2JA5 D;  5IP9 D;  5FLM D;  2JA6 D;  4A3C D;  3HOV D;  5C3E D;  2R93 D;  4BY1 D;  2JA8 D;  1Y1W D;  4A3B D;  1Y1V D;  3H0G D;  3HOU D;  3PO3 D;  5IP7 D;  4A3G D;  4A3D D;  3I4M D;  3HOY D;  4A3F D;  3H3V E;  3HOZ D;  1WCM D;  2B63 D;  4BXX D;  4BY7 D;  4A3M D;  4A3K D;  3PO2 D; 
#chains in the Genus database with same CATH topology
 2LAG A;  3AYH A;  5C44 D;  1EMR A;  4IKZ A;  1KF9 A;  5D58 A;  3G6D A;  3DGC L;  1RCB A;  1AX8 A;  5IYC D;  4NI7 A;  5D6K A;  2JA5 D;  4NN6 A;  4JA3 A;  3HHC A;  4A3B D;  1WCM D;  1A7M A;  3UX9 A;  4D2C A;  3O7P A;  1HIK A;  2O6I A;  4MHL A;  2CYK A;  4GRW A;  1ETE A;  1HGU A;  2D48 A;  1B5L A;  3HOV D;  1HWG A;  1ILK A;  1LK3 A;  4Z5R D;  2B5I A;  1A22 A;  4I77 Z;  1WU3 I;  1HIJ A;  3HMX B;  4NN7 A;  4Q65 A;  1BP3 A;  5IYD D;  1P9M B;  3BES L;  2LMS A;  3MZG A;  1M4B A;  1RFB A;  2HYM B;  1NBP A;  2B8Z A;  4GBY A;  1Y6K L;  4CNI C;  2Q98 A;  3QAZ A;  5L6Y C;  3WCY I;  1F45 B;  1GA3 A;  5FHX A;  3Q1S I;  3OG6 A;  4OH3 A;  4ZWC A;  3L5X A;  4A3J D;  1VLK A;  3NCF A;  1I1R B;  2O27 A;  3EJJ A;  4O6K A;  3HOX D;  4QIQ A;  2ERJ D;  4ZS7 A;  3I4N D;  2B90 A;  1GNC A;  1Y6N L;  4DKF A;  1ITI A;  4YUE C;  2KZ1 A;  1M4C A;  3SE3 B;  4A3G D;  1ITL A;  4NKQ C;  1D9C A;  1FG9 A;  4BY7 D;  4U4V A;  4A3K D;  3TGX B;  5EQH A;  3D85 C;  5FUC A;  2CFP A;  3BPL A;  5E4E A;  4NEM A;  2VUM D;  4D2B A;  2R93 D;  1PW4 A;  2JA8 D;  3BPO A;  3LB6 B;  4PS4 A;  3I4M D;  2B63 D;  5TS9 A;  4TPJ A;  5C65 A;  4IU8 A;  4ZWB A;  4LEP A;  3G9V B;  5C4X D;  4LRL A;  4NI9 A;  3DI3 A;  4IKV A;  1ITF A;  4GC0 A;  1JLI A;  4W6V A;  4BY1 D;  4UVM A;  5IP7 D;  2B8U A;  1BGC A;  4ZF7 A;  4U4W A;  4D2D A;  4BBS D;  1CN4 C;  3UF2 A;  5D72 A;  4XNI A;  1IAR A;  1ALU A;  3NCE A;  5FLM D;  4FA8 E;  3N0P A;  5C3E D;  1BBN A;  3H3V E;  2L3Y A;  4U4T A;  2B91 A;  3S9D A;  3L5W I;  4A3M D;  2O26 A;  4DOH A;  3HOW D;  5EQG A;  3D87 A;  2B8X A;  4TPG A;  4GS7 A;  3O7Q A;  1HWH A;  5D22 A;  1AXI A;  3NCC A;  2OQP A;  2JA6 D;  1PV6 A;  4IKX A;  1CYL A;  3BPN A;  4EXN A;  4NEJ A;  4X51 A;  5D59 A;  3DI2 A;  3EW3 A;  3PO2 D;  4A3L D;  3QB1 A;  4OAA A;  3DLQ I;  1IK0 A;  3B5K A;  1J7V L;  2D9Q A;  3SE4 B;  4DKC A;  4A3I D;  1IRL A;  3IRH A;  1QVN A;  3H0G D;  4A3D D;  3HOZ D;  1M49 A;  1D9G A;  1F6F A;  4XNJ A;  5D28 B;  5D71 A;  1CD9 A;  1AU1 A;  1Z7C A;  1N1F A;  4YDY I;  2Z3R A;  1EER A;  1RW5 A;  4J05 A;  1IJZ A;  3WDO A;  1PGR A;  3HOU D;  4O9H A;  4A3F D;  4BXX D;  2ILK A;  3PIV A;  3INK C;  4APS A;  2Y5Y A;  4J4L C;  3UF5 A;  4ZYR A;  2V8N A;  4JR9 A;  4IKY A;  1BGE A;  3QT2 C;  3D48 P;  1EXZ A;  5LQB A;  4IU9 A;  3PO3 D;  5A2O A;  4NN5 A;  1YKB A;  4LDS A;  4DKE A;  4YPG C;  4ZW9 A;  2Q7N B;  5A2N A;  4A3E D;  4PYP A;  2B8Y A;  4YB9 D;  4EXP A;  1CSG A;  2GMF A;  1HUL A;  3OQ3 A;  3HHR A;  1M48 A;  1PW6 A;  4GBZ A;  4DKD A;  1ITM A;  3QWR B;  1V7N V;  4BBR D;  2Q14 A;  1LQS L;  3NCB A;  2R7Z D;  2C35 A;  5C7X A;  5IP9 D;  4A3C D;  1Y1W D;  2H24 A;  1M4R A;  2E9W C;  3UEZ E;  1RHG A;  1M47 A;  1V7M V;  1PV7 A;  1Y14 A;  2XQB A;  5D70 A;  2R92 D;  4IKW A;  1Z92 A;  1CNT 1;  2L3O A;  4WRL B;  1EKU A;  1LKI A;  2PSM A;  4YQX A;  1Y6M L;  3VA2 A;  1HZI A;  5EQI A;  4RS1 A;  3PIW A;  3LB6 A;  4YBQ A;  2INT A;  1BUY A;  4JRE A;  1BCN A;  1PY2 A;  2IL6 A;  2JA7 D;  1PVH B;  3QB7 A;  4A93 D;  3OG4 A;  1BGD A;  1INR A;  5KNH I;  1IL6 A;  1FYH A;  5IYB D;  5GXB A;  3N06 A;  3NPZ A;  3FKI D;  2Z3Q A;  1SCF A;  1EVS A;  4TPH A;  2CFQ A;  2XUT A;  1Y1V D;  1HUW A;  3HOY D;  1M4A A;  3DUH C; 
#chains in the Genus database with same CATH homology
 2LAG A;  3AYH A;  4DKD A;  1ITM A;  1EMR A;  5C44 D;  1KF9 A;  3D85 C;  3QWR B;  4A3L D;  3G6D A;  3DGC L;  1V7N V;  3QB1 A;  4BBR D;  2Q14 A;  1RCB A;  5FUC A;  3DLQ I;  1LQS L;  1IK0 A;  1AX8 A;  3NCB A;  5IYC D;  3B5K A;  2C35 A;  4NI7 A;  1J7V L;  2D9Q A;  3SE4 B;  5C7X A;  2R7Z D;  4DKC A;  3BPL A;  4A3I D;  1IRL A;  5E4E A;  4NEM A;  2JA5 D;  2VUM D;  4NN6 A;  5IP9 D;  4A3C D;  3IRH A;  2R93 D;  2JA8 D;  3BPO A;  1Y1W D;  1QVN A;  1M4R A;  2H24 A;  3HHC A;  3H0G D;  3LB6 B;  4PS4 A;  2E9W C;  4A3B D;  4A3D D;  3I4M D;  3HOZ D;  1M49 A;  3UEZ E;  1WCM D;  2B63 D;  5TS9 A;  1RHG A;  1D9G A;  1F6F A;  1M47 A;  3UX9 A;  1A7M A;  1V7M V;  5D28 B;  1Y14 A;  2XQB A;  5D70 A;  5D71 A;  2R92 D;  3G9V B;  1CD9 A;  1AU1 A;  1Z7C A;  3QT2 C;  1N1F A;  5C4X D;  4LRL A;  1HIK A;  4YDY I;  2O6I A;  1EER A;  2Z3R A;  4NI9 A;  4MHL A;  1Z92 A;  1CNT 1;  1RW5 A;  2CYK A;  1ETE A;  3DI3 A;  1HGU A;  4GRW A;  2D48 A;  1IJZ A;  2L3O A;  1ITF A;  4WRL B;  1B5L A;  1EKU A;  1JLI A;  3HOV D;  1PGR A;  4BY1 D;  3HOU D;  1HWG A;  1LKI A;  1ILK A;  2B8U A;  4O9H A;  2PSM A;  5IP7 D;  4A3F D;  4YQX A;  1Y6M L;  3VA2 A;  1HZI A;  1LK3 A;  4Z5R D;  4RS1 A;  2B5I A;  1BGC A;  1A22 A;  4I77 Z;  2ILK A;  4ZF7 A;  4BXX D;  3PIV A;  3PIW A;  3LB6 A;  1WU3 I;  1HIJ A;  4BBS D;  1CN4 C;  3HMX B;  2INT A;  3INK C;  4NN7 A;  1BUY A;  4J4L C;  3UF5 A;  1BCN A;  1PY2 A;  2IL6 A;  3UF2 A;  5D72 A;  1BGE A;  1IAR A;  1ALU A;  1BP3 A;  3D48 P;  1P9M B;  3BES L;  1EXZ A;  1PVH B;  2LMS A;  3QB7 A;  5IYD D;  3MZG A;  1M4B A;  2JA7 D;  5LQB A;  1RFB A;  3OG4 A;  2HYM B;  1NBP A;  4A93 D;  3NCE A;  1BGD A;  5FLM D;  2B8Z A;  3N0P A;  4FA8 E;  5C3E D;  1Y6K L;  1INR A;  1BBN A;  4CNI C;  2Q98 A;  3PO3 D;  4NN5 A;  3QAZ A;  3H3V E;  2L3Y A;  5L6Y C;  3WCY I;  1YKB A;  2B91 A;  4DKE A;  1F45 B;  1GA3 A;  5FHX A;  3S9D A;  5KNH I;  1IL6 A;  1FYH A;  3L5W I;  3Q1S I;  3OG6 A;  4YPG C;  2Q7N B;  2O26 A;  4A3M D;  4DOH A;  3HOW D;  3D87 A;  2B8X A;  3L5X A;  5IYB D;  1VLK A;  4A3J D;  3NCF A;  3N06 A;  3NPZ A;  3FKI D;  4GS7 A;  1I1R B;  2O27 A;  3EJJ A;  4A3E D;  2Z3Q A;  1HWH A;  4O6K A;  5D22 A;  3HOX D;  1SCF A;  2ERJ D;  1AXI A;  1EVS A;  2B8Y A;  4ZS7 A;  3NCC A;  3I4N D;  2B90 A;  1GNC A;  1Y6N L;  2OQP A;  4DKF A;  4EXP A;  2JA6 D;  1ITI A;  1CSG A;  2GMF A;  4YUE C;  2KZ1 A;  1CYL A;  1HUL A;  1M4C A;  3OQ3 A;  3HHR A;  1Y1V D;  1M48 A;  3SE3 B;  4A3G D;  1HUW A;  1ITL A;  3HOY D;  1PW6 A;  4NKQ C;  3BPN A;  1M4A A;  1D9C A;  1FG9 A;  4EXN A;  4NEJ A;  4X51 A;  3DI2 A;  3DUH C;  3EW3 A;  4BY7 D;  4A3K D;  3TGX B;  3PO2 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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