3FKID

12-subunit rna polymerase ii refined with zn-sad data
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
218
structure length
178
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKETREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 42
structure length 178
sequence length 218
ec nomenclature
pdb deposition date 2008-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3fkiD02
4A3ED 1Y1VD 4A3CD 5C3ED 2JA6D 5C4XD 4A3LD 5IP7D 3AYHA 4A3ID 4A3DD 3H0GD 2R92D 2VUMD 4A3FD 3FKID 4A3JD 4BY1D 3HOUD 4A3BD 3H3VE 4A3MD 3HOVD 2JA5D 3I4MD 2R7ZD 3HOWD 4BY7D 3HOYD 3HOZD 3HOXD 3PO3D 1WCMD 2JA8D 5IYBD 4A93D 5IP9D 2B63D 3I4ND 1Y1WD 4BBSD 4A3GD 1Y14A 4BBRD 5IYCD 5IYDD 4A3KD 2C35A 4BXXD 2R93D 2JA7D 3PO2D 5C44D 5FLMD
chains in the Genus database with same CATH superfamily
4A3ED 1IRLA 1HIJA 1HUWA 1RW5A 4A3DD 1LQSL 2HYMB 1CN4C 2Z3QA 4GBZA 3TGXB 5D6KA 1PY2A 4DKCA 4D2BA 3PIVA 1EXZA 5EQHA 1B5LA 4I77Z 5D28B 4IKZA 1M4CA 2KZ1A 3BPNA 4TPJA 1M47A 4YDYI 2XQBA 1SCFA 1M4AA 3DI3A 3N0PA 4YPGC 1Z7CA 4NI7A 4GS7A 1BUYA 4ZWCA 1GA3A 4YBQA 4DKEA 1HWGA 4ZYRA 4PS4A 4MHLA 1ITFA 3FKID 2L3YA 4U4WA 5GXBA 1WU3I 1PVHB 4ZWBA 1IARA 1AU1A 3D85C 4A3GD 3BESL 2JA7D 4Z5RD 1BGDA 3IRHA 5C65A 4U4VA 3VA2A 2Q14A 3S9DA 1CSGA 3NCCA 4NN5A 5EQIA 4OH3A 3EJJA 1CYLA 1AX8A 3HOZD 2D48A 1ILKA 5L6YC 1RCBA 5D70A 1EERA 2B63D 4DOHA 5TS9A 4BBSD 1JLIA 5IYDD 3QWRB 4GC0A 5D22A 1A7MA 1ITLA 2B91A 4O9HA 2ILKA 1A22A 2JA6D 3O7PA 2O6IA 4DKDA 4NN7A 5D59A 2CYKA 2CFPA 4APSA 3PO3D 3HMXB 5EQGA 2XUTA 4IKWA 3WCYI 5D72A 1P9MB 1HZIA 4JR9A 4IU8A 4NKQC 3L5WI 2B8UA 4UVMA 1BGEA 1HGUA 5IP7D 1PW6A 1Y6KL 4A3ID 3BPLA 3UF5A 2B8XA 4A3JD 3QB7A 4A3BD 3DUHC 4LDSA 1D9GA 1PGRA 3UF2A 4IKVA 2R7ZD 3HOWD 1HIKA 1WCMD 2INTA 4IKYA 3G9VB 1PW4A 3NCEA 1Y6NL 2L3OA 5D58A 4GRWA 3NCBA 4YQXA 1BP3A 4JREA 3G6DA 1ETEA 4A3CD 1FG9A 1RFBA 3HOUD 4NEJA 4A3MD 1PV7A 4XNIA 1HULA 4YUEC 2O26A 3I4ND 2PSMA 1D9CA 2B90A 3MZGA 3QT2C 4O6KA 1AXIA 2JA5D 5FUCA 3HOXD 2Q98A 4D2CA 3DI2A 1ITMA 1EVSA 1CD9A 3QB1A 1BGCA 2R93D 2V8NA 1IJZA 1EMRA 2ERJD 4LEPA 4EXNA 5C4XD 3AYHA 1N1FA 1IL6A 1VLKA 1RHGA 1M48A 4NN6A 4PYPA 3I4MD 3OG4A 5A2NA 2JA8D 2IL6A 3Q1SI 1YKBA 5C44D 4J05A 3SE3B 4OAAA 2D9QA 1HWHA 3QAZA 4BY1D 1INRA 4LRLA 1F6FA 5A2OA 1M49A 4YB9D 1F45B 3WDOA 4WRLB 1Y14A 4BXXD 2B8YA 2C35A 1BBNA 3SE4B 5C3ED 2VUMD 4A3FD 4ZF7A 1Y6ML 2OQPA 4Q65A 3N06A 4J4LC 4RS1A 1I1RB 4IU9A 3HHRA 1PV6A 4A93D 1BCNA 2Q7NB 4TPHA 2E9WC 5C7XA 1Y1VD 4GBYA 4A3LD 4D2DA 4U4TA 1EKUA 2CFQA 4DKFA 1LK3A 4XNJA 2LMSA 1Y1WD 1LKIA 3B5KA 5D71A 5IYCD 1NBPA 3D87A 5IP9D 4FA8E 4TPGA 4NEMA 3UEZE 5FHXA 3LB6B 3DGCL 1ALUA 2Y5YA 3H3VE 3NCFA 2Z3RA 3HOVD 3UX9A 2O27A 1M4RA 4ZW9A 1KF9A 1IK0A 4NI9A 5IYBD 3EW3A 3D48P 3PO2D 3BPOA 5E4EA 4CNIC 1CNT1 4JA3A 2LAGA 3H0GD 2R92D 4IKXA 3NPZA 3O7QA 3PIWA 3HHCA 2B8ZA 1V7MV 1J7VL 3L5XA 1GNCA 3DLQI 4BBRD 4A3KD 1V7NV 1Z92A 4W6VA 1FYHA 3OQ3A 2B5IA 4QIQA 3LB6A 3INKC 5LQBA 4X51A 2GMFA 5KNHI 1M4BA 4BY7D 3HOYD 4ZS7A 2H24A 3OG6A 1QVNA 1ITIA 4EXPA 5FLMD
chains in the Genus database with same CATH topology
4A3ED 1A7MA 1ITLA 1Y1VD 2B90A 2B91A 1IRLA 1A22A 1HIJA 2ILKA 1HUWA 4O9HA 2JA6D 1RW5A 3MZGA 4A3LD 4A3DD 2O6IA 4DKDA 1LQSL 2HYMB 1CN4C 2Z3QA 3QT2C 4O6KA 4NN7A 2CYKA 1AXIA 3TGXB 1Y1WD 5D22A 2JA5D 1EKUA 5FUCA 1PY2A 3HOXD 2Q98A 3PO3D 4DKFA 4BXXD 1LK3A 3DI2A 1ITMA 4DKCA 3HMXB 1EVSA 1CD9A 2LMSA 3QB1A 5D72A 1P9MB 3WCYI 1LKIA 3B5KA 1HZIA 3PIVA 1BGCA 5D71A 5IYCD 2R93D 4NKQC 1NBPA 1EXZA 3L5WI 2B8UA 1IJZA 3D87A 1EMRA 5IP9D 1B5LA 4FA8E 4I77Z 5D28B 2ERJD 1BGEA 4EXNA 1HGUA 4NEMA 5C4XD 3UEZE 5FHXA 5IP7D 1PW6A 1N1FA 1Y6KL 1M4CA 3AYHA 4A3ID 2KZ1A 3LB6B 3BPLA 3UF5A 1IL6A 1VLKA 2B8XA 1RHGA 3BPNA 3DGCL 1M48A 3QB7A 4A3JD 1ALUA 4A3BD 3DUHC 4NN6A 3H3VE 4YDYI 1D9GA 2Z3RA 3NCFA 1PGRA 3UF2A 2XQBA 1SCFA 3UX9A 1M4AA 2O27A 3HOVD 3HOWD 3I4MD 2R7ZD 1HIKA 3DI3A 1M4RA 3N0PA 1KF9A 3OG4A 1IK0A 1WCMD 4NI9A 2JA8D 2INTA 5IYBD 4YPGC 3EW3A 1Z7CA 4NI7A 3D48P 2IL6A 3Q1SI 1YKBA 4GS7A 1BUYA 3PO2D 5C44D 1GA3A 3SE3B 3G9VB 3BPOA 5E4EA 4DKEA 2D9QA 4CNIC 1HWGA 1CNT1 1HWHA 4PS4A 3NCEA 3QAZA 2LAGA 1Y6NL 2L3OA 3H0GD 2R92D 4MHLA 1ITFA 3NPZA 3FKID 1INRA 4GRWA 4BY1D 2L3YA 1F6FA 4LRLA 1M49A 1WU3I 3PIWA 1PVHB 3HHCA 2B8ZA 1F45B 3NCBA 1V7MV 1J7VL 4YQXA 1IARA 1BP3A 3L5XA 1GNCA 3DLQI 1AU1A 4WRLB 3D85C 4A3GD 1Y14A 4BBRD 2B8YA 3BESL 3G6DA 2C35A 1V7NV 1Z92A 4A3KD 2JA7D 1ETEA 4Z5RD 1BBNA 1FYHA 3SE4B 3OQ3A 1BGDA 2B5IA 4A3CD 3IRHA 5C3ED 3LB6A 3VA2A 1FG9A 1RFBA 2Q14A 3INKC 1CSGA 5LQBA 3S9DA 3NCCA 4NN5A 4X51A 2VUMD 4A3FD 3HOUD 4ZF7A 3EJJA 5FLMD 1Y6ML 2OQPA 3N06A 4J4LC 2GMFA 4RS1A 4NEJA 4A3MD 5KNHI 1M4BA 1I1RB 1CYLA 4BY7D 1AX8A 3HOYD 4ZS7A 3HOZD 2D48A 2H24A 1ILKA 3HHRA 3OG6A 5L6YC 1RCBA 5D70A 1HULA 4YUEC 1EERA 4A93D 2B63D 1QVNA 2O26A 4DOHA 3I4ND 4EXPA 1BCNA 5TS9A 2Q7NB 4BBSD 1ITIA 2PSMA 1JLIA 5IYDD 1D9CA 3QWRB 2E9WC 5C7XA 1M47A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3E D;  1Y1V D;  4A3C D;  5C3E D;  2JA6 D;  5C4X D;  4A3L D;  5IP7 D;  3AYH A;  4A3I D;  4A3D D;  3H0G D;  2R92 D;  2VUM D;  4A3F D;  3FKI D;  4A3J D;  4BY1 D;  3HOU D;  4A3B D;  3H3V E;  4A3M D;  3HOV D;  2JA5 D;  3I4M D;  2R7Z D;  3HOW D;  4BY7 D;  3HOY D;  3HOZ D;  3HOX D;  3PO3 D;  1WCM D;  2JA8 D;  5IYB D;  4A93 D;  5IP9 D;  2B63 D;  3I4N D;  1Y1W D;  4BBS D;  4A3G D;  1Y14 A;  4BBR D;  5IYC D;  5IYD D;  4A3K D;  2C35 A;  4BXX D;  2R93 D;  2JA7 D;  3PO2 D;  5C44 D;  5FLM D; 
#chains in the Genus database with same CATH topology
 4A3E D;  1IRL A;  1HIJ A;  1HUW A;  1RW5 A;  4A3D D;  1LQS L;  2HYM B;  1CN4 C;  2Z3Q A;  4GBZ A;  3TGX B;  5D6K A;  1PY2 A;  4DKC A;  4D2B A;  3PIV A;  1EXZ A;  5EQH A;  1B5L A;  4I77 Z;  5D28 B;  4IKZ A;  1M4C A;  2KZ1 A;  3BPN A;  4TPJ A;  1M47 A;  4YDY I;  2XQB A;  1SCF A;  1M4A A;  3DI3 A;  3N0P A;  4YPG C;  1Z7C A;  4NI7 A;  4GS7 A;  1BUY A;  4ZWC A;  1GA3 A;  4YBQ A;  4DKE A;  1HWG A;  4ZYR A;  4PS4 A;  4MHL A;  1ITF A;  3FKI D;  2L3Y A;  4U4W A;  5GXB A;  1WU3 I;  1PVH B;  4ZWB A;  1IAR A;  1AU1 A;  3D85 C;  4A3G D;  3BES L;  2JA7 D;  4Z5R D;  1BGD A;  3IRH A;  5C65 A;  4U4V A;  3VA2 A;  2Q14 A;  3S9D A;  1CSG A;  3NCC A;  4NN5 A;  5EQI A;  4OH3 A;  3EJJ A;  1CYL A;  1AX8 A;  3HOZ D;  2D48 A;  1ILK A;  5L6Y C;  1RCB A;  5D70 A;  1EER A;  2B63 D;  4DOH A;  5TS9 A;  4BBS D;  1JLI A;  5IYD D;  3QWR B;  4GC0 A;  5D22 A;  1A7M A;  1ITL A;  2B91 A;  4O9H A;  2ILK A;  1A22 A;  2JA6 D;  3O7P A;  2O6I A;  4DKD A;  4NN7 A;  5D59 A;  2CYK A;  2CFP A;  4APS A;  3PO3 D;  3HMX B;  5EQG A;  2XUT A;  4IKW A;  3WCY I;  5D72 A;  1P9M B;  1HZI A;  4JR9 A;  4IU8 A;  4NKQ C;  3L5W I;  2B8U A;  4UVM A;  1BGE A;  1HGU A;  5IP7 D;  1PW6 A;  1Y6K L;  4A3I D;  3BPL A;  3UF5 A;  2B8X A;  4A3J D;  3QB7 A;  4A3B D;  3DUH C;  4LDS A;  1D9G A;  1PGR A;  3UF2 A;  4IKV A;  2R7Z D;  3HOW D;  1HIK A;  1WCM D;  2INT A;  4IKY A;  3G9V B;  1PW4 A;  3NCE A;  1Y6N L;  2L3O A;  5D58 A;  4GRW A;  3NCB A;  4YQX A;  1BP3 A;  4JRE A;  3G6D A;  1ETE A;  4A3C D;  1FG9 A;  1RFB A;  3HOU D;  4NEJ A;  4A3M D;  1PV7 A;  4XNI A;  1HUL A;  4YUE C;  2O26 A;  3I4N D;  2PSM A;  1D9C A;  2B90 A;  3MZG A;  3QT2 C;  4O6K A;  1AXI A;  2JA5 D;  5FUC A;  3HOX D;  2Q98 A;  4D2C A;  3DI2 A;  1ITM A;  1EVS A;  1CD9 A;  3QB1 A;  1BGC A;  2R93 D;  2V8N A;  1IJZ A;  1EMR A;  2ERJ D;  4LEP A;  4EXN A;  5C4X D;  3AYH A;  1N1F A;  1IL6 A;  1VLK A;  1RHG A;  1M48 A;  4NN6 A;  4PYP A;  3I4M D;  3OG4 A;  5A2N A;  2JA8 D;  2IL6 A;  3Q1S I;  1YKB A;  5C44 D;  4J05 A;  3SE3 B;  4OAA A;  2D9Q A;  1HWH A;  3QAZ A;  4BY1 D;  1INR A;  4LRL A;  1F6F A;  5A2O A;  1M49 A;  4YB9 D;  1F45 B;  3WDO A;  4WRL B;  1Y14 A;  4BXX D;  2B8Y A;  2C35 A;  1BBN A;  3SE4 B;  5C3E D;  2VUM D;  4A3F D;  4ZF7 A;  1Y6M L;  2OQP A;  4Q65 A;  3N06 A;  4J4L C;  4RS1 A;  1I1R B;  4IU9 A;  3HHR A;  1PV6 A;  4A93 D;  1BCN A;  2Q7N B;  4TPH A;  2E9W C;  5C7X A;  1Y1V D;  4GBY A;  4A3L D;  4D2D A;  4U4T A;  1EKU A;  2CFQ A;  4DKF A;  1LK3 A;  4XNJ A;  2LMS A;  1Y1W D;  1LKI A;  3B5K A;  5D71 A;  5IYC D;  1NBP A;  3D87 A;  5IP9 D;  4FA8 E;  4TPG A;  4NEM A;  3UEZ E;  5FHX A;  3LB6 B;  3DGC L;  1ALU A;  2Y5Y A;  3H3V E;  3NCF A;  2Z3R A;  3HOV D;  3UX9 A;  2O27 A;  1M4R A;  4ZW9 A;  1KF9 A;  1IK0 A;  4NI9 A;  5IYB D;  3EW3 A;  3D48 P;  3PO2 D;  3BPO A;  5E4E A;  4CNI C;  1CNT 1;  4JA3 A;  2LAG A;  3H0G D;  2R92 D;  4IKX A;  3NPZ A;  3O7Q A;  3PIW A;  3HHC A;  2B8Z A;  1V7M V;  1J7V L;  3L5X A;  1GNC A;  3DLQ I;  4BBR D;  4A3K D;  1V7N V;  1Z92 A;  4W6V A;  1FYH A;  3OQ3 A;  2B5I A;  4QIQ A;  3LB6 A;  3INK C;  5LQB A;  4X51 A;  2GMF A;  5KNH I;  1M4B A;  4BY7 D;  3HOY D;  4ZS7 A;  2H24 A;  3OG6 A;  1QVN A;  1ITI A;  4EXP A;  5FLM D; 
#chains in the Genus database with same CATH homology
 4A3E D;  1A7M A;  1ITL A;  1Y1V D;  2B90 A;  2B91 A;  1IRL A;  1A22 A;  1HIJ A;  2ILK A;  1HUW A;  4O9H A;  2JA6 D;  1RW5 A;  3MZG A;  4A3L D;  4A3D D;  2O6I A;  4DKD A;  1LQS L;  2HYM B;  1CN4 C;  2Z3Q A;  3QT2 C;  4O6K A;  4NN7 A;  2CYK A;  1AXI A;  3TGX B;  1Y1W D;  5D22 A;  2JA5 D;  1EKU A;  5FUC A;  1PY2 A;  3HOX D;  2Q98 A;  3PO3 D;  4DKF A;  4BXX D;  1LK3 A;  3DI2 A;  1ITM A;  4DKC A;  3HMX B;  1EVS A;  1CD9 A;  2LMS A;  3QB1 A;  5D72 A;  1P9M B;  3WCY I;  1LKI A;  3B5K A;  1HZI A;  3PIV A;  1BGC A;  5D71 A;  5IYC D;  2R93 D;  4NKQ C;  1NBP A;  1EXZ A;  3L5W I;  2B8U A;  1IJZ A;  3D87 A;  1EMR A;  5IP9 D;  1B5L A;  4FA8 E;  4I77 Z;  5D28 B;  2ERJ D;  1BGE A;  4EXN A;  1HGU A;  4NEM A;  5C4X D;  3UEZ E;  5FHX A;  5IP7 D;  1PW6 A;  1N1F A;  1Y6K L;  1M4C A;  3AYH A;  4A3I D;  2KZ1 A;  3LB6 B;  3BPL A;  3UF5 A;  1IL6 A;  1VLK A;  2B8X A;  1RHG A;  3BPN A;  3DGC L;  1M48 A;  3QB7 A;  4A3J D;  1ALU A;  4A3B D;  3DUH C;  4NN6 A;  3H3V E;  4YDY I;  1D9G A;  2Z3R A;  3NCF A;  1PGR A;  3UF2 A;  2XQB A;  1SCF A;  3UX9 A;  1M4A A;  2O27 A;  3HOV D;  3HOW D;  3I4M D;  2R7Z D;  1HIK A;  3DI3 A;  1M4R A;  3N0P A;  1KF9 A;  3OG4 A;  1IK0 A;  1WCM D;  4NI9 A;  2JA8 D;  2INT A;  5IYB D;  4YPG C;  3EW3 A;  1Z7C A;  4NI7 A;  3D48 P;  2IL6 A;  3Q1S I;  1YKB A;  4GS7 A;  1BUY A;  3PO2 D;  5C44 D;  1GA3 A;  3SE3 B;  3G9V B;  3BPO A;  5E4E A;  4DKE A;  2D9Q A;  4CNI C;  1HWG A;  1CNT 1;  1HWH A;  4PS4 A;  3NCE A;  3QAZ A;  2LAG A;  1Y6N L;  2L3O A;  3H0G D;  2R92 D;  4MHL A;  1ITF A;  3NPZ A;  3FKI D;  1INR A;  4GRW A;  4BY1 D;  2L3Y A;  1F6F A;  4LRL A;  1M49 A;  1WU3 I;  3PIW A;  1PVH B;  3HHC A;  2B8Z A;  1F45 B;  3NCB A;  1V7M V;  1J7V L;  4YQX A;  1IAR A;  1BP3 A;  3L5X A;  1GNC A;  3DLQ I;  1AU1 A;  4WRL B;  3D85 C;  4A3G D;  1Y14 A;  4BBR D;  2B8Y A;  3BES L;  3G6D A;  2C35 A;  1V7N V;  1Z92 A;  4A3K D;  2JA7 D;  1ETE A;  4Z5R D;  1BBN A;  1FYH A;  3SE4 B;  3OQ3 A;  1BGD A;  2B5I A;  4A3C D;  3IRH A;  5C3E D;  3LB6 A;  3VA2 A;  1FG9 A;  1RFB A;  2Q14 A;  3INK C;  1CSG A;  5LQB A;  3S9D A;  3NCC A;  4NN5 A;  4X51 A;  2VUM D;  4A3F D;  3HOU D;  4ZF7 A;  3EJJ A;  5FLM D;  1Y6M L;  2OQP A;  3N06 A;  4J4L C;  2GMF A;  4RS1 A;  4NEJ A;  4A3M D;  5KNH I;  1M4B A;  1I1R B;  1CYL A;  4BY7 D;  1AX8 A;  3HOY D;  4ZS7 A;  3HOZ D;  2D48 A;  2H24 A;  1ILK A;  3HHR A;  3OG6 A;  5L6Y C;  1RCB A;  5D70 A;  1HUL A;  4YUE C;  1EER A;  4A93 D;  2B63 D;  1QVN A;  2O26 A;  4DOH A;  3I4N D;  4EXP A;  1BCN A;  5TS9 A;  2Q7N B;  4BBS D;  1ITI A;  2PSM A;  1JLI A;  5IYD D;  1D9C A;  3QWR B;  2E9W C;  5C7X A;  1M47 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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