3H3VE

Yeast rnap ii containing poly(a)-signal sequence in the active site
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
218
structure length
177
Chain Sequence
STSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro
pubmed doi rcsb
molecule tags Transferase/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 43
structure length 177
sequence length 218
ec nomenclature
pdb deposition date 2009-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3h3vE02
5FLMD 4A3FD 4A3MD 2VUMD 1Y14A 5IYBD 4A3GD 5IYCD 3H0GD 5C44D 1Y1VD 2JA5D 4A93D 4BXXD 5IP7D 1Y1WD 2JA7D 4A3DD 5IP9D 3PO2D 5C3ED 3HOVD 4A3BD 3PO3D 4A3KD 3HOYD 3HOXD 4BY7D 5IYDD 3AYHA 2C35A 4A3ED 3H3VE 4A3LD 4A3CD 4BBRD 3HOWD 2JA6D 4BBSD 3I4MD 3HOZD 4A3ID 3FKID 1WCMD 2JA8D 3HOUD 4A3JD 5C4XD 2R93D 3I4ND 2B63D 4BY1D 2R7ZD 2R92D
chains in the Genus database with same CATH superfamily
1AU1A 1V7NV 3D85C 5IP9D 1P9MB 1F6FA 2GMFA 1M48A 3HOXD 2Z3QA 3HHCA 2L3OA 1Y6KL 1RCBA 3EW3A 4ZW9A 5D59A 2IL6A 4XNJA 4YB9D 2Q98A 4NI9A 3NPZA 3UF2A 4ZS7A 1Y6NL 1NBPA 4YUEC 3HOVD 1BBNA 2D48A 4A3ED 1I1RB 2B8UA 5D70A 2LAGA 1CN4C 1YKBA 4ZWBA 2B8YA 4U4WA 1HWHA 1FYHA 4A3FD 2L3YA 3UEZE 1Y14A 1Y1VD 2B90A 1EERA 1RFBA 2HYMB 1ITFA 3BPNA 1A7MA 4OH3A 1IARA 1EVSA 4ZWCA 1GA3A 3HOWD 2JA6D 4U4TA 2Z3RA 5A2NA 3EJJA 3DI3A 1PV7A 1BGCA 2XUTA 4MHLA 4A3MD 1SCFA 4APSA 5TS9A 5KNHI 1Y1WD 5FHXA 4W6VA 5L6YC 2LMSA 4A3DD 3UF5A 4BBRD 4GC0A 1B5LA 1RHGA 4IKXA 5D28B 4U4VA 5D72A 2B63D 1PV6A 2Q7NB 2H24A 4PYPA 4DKFA 4IKZA 1PY2A 2CFPA 3S9DA 1A22A 4NI7A 1BCNA 1F45B 3HOUD 4DOHA 5C4XD 4DKEA 4TPHA 1HUWA 1IL6A 3O7QA 4GS7A 4X51A 4NKQC 4D2CA 3LB6A 3PO3D 3NCBA 1EKUA 4ZF7A 4NN6A 3WDOA 2B91A 2V8NA 4JREA 3I4ND 3UX9A 1KF9A 4JA3A 1PVHB 4WRLB 5EQHA 4DKCA 3Q1SI 5IP7D 2JA7D 1M49A 3D48P 3QB1A 3N06A 4IKWA 2O27A 1HGUA 3HMXB 3FKID 1WCMD 1M47A 2VUMD 1HWGA 5A2OA 1ITIA 4O9HA 5EQGA 1CSGA 3PO2D 4QIQA 5C3ED 1IRLA 5C7XA 1ALUA 4A3LD 3OG6A 4EXPA 1LK3A 4BY1D 4YPGC 2ILKA 4I77Z 2B8ZA 4NEJA 2D9QA 2B8XA 1CNT1 2CYKA 2B5IA 4RS1A 3NCEA 1FG9A 1ILKA 3NCFA 2C35A 3BPOA 3HOZD 4D2BA 3PIVA 4A3JD 2R93D 1INRA 1J7VL 1GNCA 4D2DA 5D58A 3L5XA 5IYCD 3H0GD 4IU9A 1HZIA 4GBYA 1VLKA 3IRHA 1LQSL 2CFQA 1ITLA 4OAAA 1V7MV 3DI2A 1WU3I 1HIJA 1IK0A 2R92D 1Z92A 3SE4B 1PGRA 3D87A 4LEPA 4IKYA 4NN5A 2E9WC 3O7PA 1PW4A 1HIKA 4ZYRA 1ITMA 4A3BD 4J4LC 1M4BA 4A3CD 4TPJA 3LB6B 4BBSD 3I4MD 1D9GA 1D9CA 3HHRA 3N0PA 4TPGA 5FLMD 5C65A 1EXZA 2PSMA 5C44D 1CYLA 3OG4A 2KZ1A 3VA2A 2O6IA 2OQPA 3L5WI 5D6KA 4A3KD 3G6DA 4YBQA 1QVNA 3QWRB 5LQBA 1PW6A 5E4EA 1M4CA 4A3GD 4PS4A 4IU8A 3BPLA 3PIWA 4YDYI 1ETEA 4GBZA 4JR9A 1Y6ML 1IJZA 3DGCL 4LRLA 5D71A 4YQXA 1M4AA 2ERJD 4A93D 4DKDA 4BXXD 4NN7A 4LDSA 1Z7CA 4IKVA 1AX8A 2O26A 4XNIA 3HOYD 4BY7D 3MZGA 4NEMA 1CD9A 2Q14A 4J05A 2JA8D 5FUCA 3SE3B 4O6KA 4GRWA 2XQBA 2Y5YA 5GXBA 1BUYA 1BP3A 5IYBD 1BGEA 3NCCA 1AXIA 1HULA 1BGDA 1LKIA 1RW5A 4UVMA 4A3ID 3WCYI 1JLIA 2R7ZD 1N1FA 3QT2C 4EXNA 3B5KA 4FA8E 3QB7A 2JA5D 1M4RA 3QAZA 5D22A 4Z5RD 4CNIC 5IYDD 3AYHA 3H3VE 1EMRA 4Q65A 3TGXB 3DUHC 3BESL 2INTA 3G9VB 3INKC 3DLQI 5EQIA 3OQ3A
chains in the Genus database with same CATH topology
4YPGC 2Q7NB 2ILKA 4I77Z 2B8ZA 1M4CA 5E4EA 2H24A 4NEJA 4A3GD 4DKFA 2D9QA 2B8XA 4PS4A 1AU1A 1CNT1 1V7NV 3BPLA 2CYKA 3D85C 1PY2A 2B5IA 5IP9D 4RS1A 1P9MB 3PIWA 1F6FA 3NCEA 4YDYI 2GMFA 1FG9A 1ETEA 1M48A 1ILKA 3NCFA 3HOXD 2Z3QA 2C35A 3HHCA 2L3OA 1Y6KL 3S9DA 3BPOA 1RCBA 1A22A 3EW3A 3HOZD 4NI7A 1BCNA 1F45B 3PIVA 3HOUD 4DOHA 1Y6ML 1IJZA 3DGCL 4LRLA 5D71A 1INRA 4DKEA 4A3JD 2R93D 5C4XD 1HUWA 1J7VL 1IL6A 2IL6A 1GNCA 3L5XA 4YQXA 4GS7A 2Q98A 5IYCD 1M4AA 3H0GD 1HZIA 2ERJD 4X51A 4NKQC 4A93D 1VLKA 3IRHA 4DKDA 4NI9A 4BXXD 4NN7A 1Z7CA 1LQSL 3NPZA 3UF2A 1AX8A 4ZS7A 1Y6NL 1NBPA 2O26A 4YUEC 3HOVD 3LB6A 3PO3D 3HOYD 4BY7D 1BBNA 2D48A 3NCBA 3MZGA 4A3ED 4NEMA 1ITLA 1CD9A 1I1RB 1V7MV 2B8UA 1EKUA 2LAGA 2Q14A 1WU3I 3DI2A 5D70A 1CN4C 4NN6A 1YKBA 4ZF7A 1HIJA 1IK0A 2B91A 2JA8D 2B8YA 5FUCA 3I4ND 3SE3B 1HWHA 2R92D 1Z92A 3SE4B 3UX9A 1KF9A 1FYHA 4O6KA 1PGRA 4GRWA 2JA6D 4A3FD 2L3YA 2XQBA 3D87A 3UEZE 1BUYA 1PVHB 1BP3A 1Y14A 5IYBD 4WRLB 1BGEA 1Y1VD 4DKCA 2B90A 3Q1SI 1EERA 1RFBA 2HYMB 4NN5A 5IP7D 2E9WC 1ITFA 3BPNA 2JA7D 1M49A 3NCCA 1A7MA 1AXIA 1IARA 1HIKA 1EVSA 3D48P 1HULA 1ITMA 4A3BD 1GA3A 4J4LC 1BGDA 1M4BA 3QB1A 3N06A 1LKIA 4A3CD 3HOWD 2O27A 1HGUA 1RW5A 3LB6B 3HMXB 1D9GA 1WCMD 3FKID 2Z3RA 4A3ID 3I4MD 4BBSD 3WCYI 3EJJA 1D9CA 3HHRA 3DI3A 3N0PA 1JLIA 1M47A 2R7ZD 1BGCA 5FLMD 1N1FA 3QT2C 4MHLA 4EXNA 4A3MD 2VUMD 1SCFA 1HWGA 3B5KA 4FA8E 1ITIA 1EXZA 2PSMA 3QB7A 4O9HA 5C44D 5TS9A 1M4RA 3OG4A 5KNHI 2JA5D 1CYLA 2KZ1A 1Y1WD 5FHXA 5L6YC 2LMSA 1CSGA 3VA2A 4A3DD 2O6IA 3QAZA 2OQPA 3PO2D 5D22A 5C3ED 3UF5A 4Z5RD 3L5WI 4CNIC 1IRLA 4A3KD 5C7XA 5IYDD 3AYHA 3H3VE 1ALUA 3G6DA 1EMRA 3TGXB 4BBRD 4A3LD 3DUHC 3BESL 1B5LA 1QVNA 3OG6A 3QWRB 4EXPA 5LQBA 1RHGA 2INTA 5D28B 1LK3A 1PW6A 5D72A 3G9VB 3INKC 2B63D 4BY1D 3DLQI 3OQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FLM D;  4A3F D;  4A3M D;  2VUM D;  1Y14 A;  5IYB D;  4A3G D;  5IYC D;  3H0G D;  5C44 D;  1Y1V D;  2JA5 D;  4A93 D;  4BXX D;  5IP7 D;  1Y1W D;  2JA7 D;  4A3D D;  5IP9 D;  3PO2 D;  5C3E D;  3HOV D;  4A3B D;  3PO3 D;  4A3K D;  3HOY D;  3HOX D;  4BY7 D;  5IYD D;  3AYH A;  2C35 A;  4A3E D;  3H3V E;  4A3L D;  4A3C D;  4BBR D;  3HOW D;  2JA6 D;  4BBS D;  3I4M D;  3HOZ D;  4A3I D;  3FKI D;  1WCM D;  2JA8 D;  3HOU D;  4A3J D;  5C4X D;  2R93 D;  3I4N D;  2B63 D;  4BY1 D;  2R7Z D;  2R92 D; 
#chains in the Genus database with same CATH topology
 1AU1 A;  1V7N V;  3D85 C;  5IP9 D;  1P9M B;  1F6F A;  2GMF A;  1M48 A;  3HOX D;  2Z3Q A;  3HHC A;  2L3O A;  1Y6K L;  1RCB A;  3EW3 A;  4ZW9 A;  5D59 A;  2IL6 A;  4XNJ A;  4YB9 D;  2Q98 A;  4NI9 A;  3NPZ A;  3UF2 A;  4ZS7 A;  1Y6N L;  1NBP A;  4YUE C;  3HOV D;  1BBN A;  2D48 A;  4A3E D;  1I1R B;  2B8U A;  5D70 A;  2LAG A;  1CN4 C;  1YKB A;  4ZWB A;  2B8Y A;  4U4W A;  1HWH A;  1FYH A;  4A3F D;  2L3Y A;  3UEZ E;  1Y14 A;  1Y1V D;  2B90 A;  1EER A;  1RFB A;  2HYM B;  1ITF A;  3BPN A;  1A7M A;  4OH3 A;  1IAR A;  1EVS A;  4ZWC A;  1GA3 A;  3HOW D;  2JA6 D;  4U4T A;  2Z3R A;  5A2N A;  3EJJ A;  3DI3 A;  1PV7 A;  1BGC A;  2XUT A;  4MHL A;  4A3M D;  1SCF A;  4APS A;  5TS9 A;  5KNH I;  1Y1W D;  5FHX A;  4W6V A;  5L6Y C;  2LMS A;  4A3D D;  3UF5 A;  4BBR D;  4GC0 A;  1B5L A;  1RHG A;  4IKX A;  5D28 B;  4U4V A;  5D72 A;  2B63 D;  1PV6 A;  2Q7N B;  2H24 A;  4PYP A;  4DKF A;  4IKZ A;  1PY2 A;  2CFP A;  3S9D A;  1A22 A;  4NI7 A;  1BCN A;  1F45 B;  3HOU D;  4DOH A;  5C4X D;  4DKE A;  4TPH A;  1HUW A;  1IL6 A;  3O7Q A;  4GS7 A;  4X51 A;  4NKQ C;  4D2C A;  3LB6 A;  3PO3 D;  3NCB A;  1EKU A;  4ZF7 A;  4NN6 A;  3WDO A;  2B91 A;  2V8N A;  4JRE A;  3I4N D;  3UX9 A;  1KF9 A;  4JA3 A;  1PVH B;  4WRL B;  5EQH A;  4DKC A;  3Q1S I;  5IP7 D;  2JA7 D;  1M49 A;  3D48 P;  3QB1 A;  3N06 A;  4IKW A;  2O27 A;  1HGU A;  3HMX B;  3FKI D;  1WCM D;  1M47 A;  2VUM D;  1HWG A;  5A2O A;  1ITI A;  4O9H A;  5EQG A;  1CSG A;  3PO2 D;  4QIQ A;  5C3E D;  1IRL A;  5C7X A;  1ALU A;  4A3L D;  3OG6 A;  4EXP A;  1LK3 A;  4BY1 D;  4YPG C;  2ILK A;  4I77 Z;  2B8Z A;  4NEJ A;  2D9Q A;  2B8X A;  1CNT 1;  2CYK A;  2B5I A;  4RS1 A;  3NCE A;  1FG9 A;  1ILK A;  3NCF A;  2C35 A;  3BPO A;  3HOZ D;  4D2B A;  3PIV A;  4A3J D;  2R93 D;  1INR A;  1J7V L;  1GNC A;  4D2D A;  5D58 A;  3L5X A;  5IYC D;  3H0G D;  4IU9 A;  1HZI A;  4GBY A;  1VLK A;  3IRH A;  1LQS L;  2CFQ A;  1ITL A;  4OAA A;  1V7M V;  3DI2 A;  1WU3 I;  1HIJ A;  1IK0 A;  2R92 D;  1Z92 A;  3SE4 B;  1PGR A;  3D87 A;  4LEP A;  4IKY A;  4NN5 A;  2E9W C;  3O7P A;  1PW4 A;  1HIK A;  4ZYR A;  1ITM A;  4A3B D;  4J4L C;  1M4B A;  4A3C D;  4TPJ A;  3LB6 B;  4BBS D;  3I4M D;  1D9G A;  1D9C A;  3HHR A;  3N0P A;  4TPG A;  5FLM D;  5C65 A;  1EXZ A;  2PSM A;  5C44 D;  1CYL A;  3OG4 A;  2KZ1 A;  3VA2 A;  2O6I A;  2OQP A;  3L5W I;  5D6K A;  4A3K D;  3G6D A;  4YBQ A;  1QVN A;  3QWR B;  5LQB A;  1PW6 A;  5E4E A;  1M4C A;  4A3G D;  4PS4 A;  4IU8 A;  3BPL A;  3PIW A;  4YDY I;  1ETE A;  4GBZ A;  4JR9 A;  1Y6M L;  1IJZ A;  3DGC L;  4LRL A;  5D71 A;  4YQX A;  1M4A A;  2ERJ D;  4A93 D;  4DKD A;  4BXX D;  4NN7 A;  4LDS A;  1Z7C A;  4IKV A;  1AX8 A;  2O26 A;  4XNI A;  3HOY D;  4BY7 D;  3MZG A;  4NEM A;  1CD9 A;  2Q14 A;  4J05 A;  2JA8 D;  5FUC A;  3SE3 B;  4O6K A;  4GRW A;  2XQB A;  2Y5Y A;  5GXB A;  1BUY A;  1BP3 A;  5IYB D;  1BGE A;  3NCC A;  1AXI A;  1HUL A;  1BGD A;  1LKI A;  1RW5 A;  4UVM A;  4A3I D;  3WCY I;  1JLI A;  2R7Z D;  1N1F A;  3QT2 C;  4EXN A;  3B5K A;  4FA8 E;  3QB7 A;  2JA5 D;  1M4R A;  3QAZ A;  5D22 A;  4Z5R D;  4CNI C;  5IYD D;  3AYH A;  3H3V E;  1EMR A;  4Q65 A;  3TGX B;  3DUH C;  3BES L;  2INT A;  3G9V B;  3INK C;  3DLQ I;  5EQI A;  3OQ3 A; 
#chains in the Genus database with same CATH homology
 4YPG C;  2Q7N B;  2ILK A;  4I77 Z;  2B8Z A;  1M4C A;  5E4E A;  2H24 A;  4NEJ A;  4A3G D;  4DKF A;  2D9Q A;  2B8X A;  4PS4 A;  1AU1 A;  1CNT 1;  1V7N V;  3BPL A;  2CYK A;  3D85 C;  1PY2 A;  2B5I A;  5IP9 D;  4RS1 A;  1P9M B;  3PIW A;  1F6F A;  3NCE A;  4YDY I;  2GMF A;  1FG9 A;  1ETE A;  1M48 A;  1ILK A;  3NCF A;  3HOX D;  2Z3Q A;  2C35 A;  3HHC A;  2L3O A;  1Y6K L;  3S9D A;  3BPO A;  1RCB A;  1A22 A;  3EW3 A;  3HOZ D;  4NI7 A;  1BCN A;  1F45 B;  3PIV A;  3HOU D;  4DOH A;  1Y6M L;  1IJZ A;  3DGC L;  4LRL A;  5D71 A;  1INR A;  4DKE A;  4A3J D;  2R93 D;  5C4X D;  1HUW A;  1J7V L;  1IL6 A;  2IL6 A;  1GNC A;  3L5X A;  4YQX A;  4GS7 A;  2Q98 A;  5IYC D;  1M4A A;  3H0G D;  1HZI A;  2ERJ D;  4X51 A;  4NKQ C;  4A93 D;  1VLK A;  3IRH A;  4DKD A;  4NI9 A;  4BXX D;  4NN7 A;  1Z7C A;  1LQS L;  3NPZ A;  3UF2 A;  1AX8 A;  4ZS7 A;  1Y6N L;  1NBP A;  2O26 A;  4YUE C;  3HOV D;  3LB6 A;  3PO3 D;  3HOY D;  4BY7 D;  1BBN A;  2D48 A;  3NCB A;  3MZG A;  4A3E D;  4NEM A;  1ITL A;  1CD9 A;  1I1R B;  1V7M V;  2B8U A;  1EKU A;  2LAG A;  2Q14 A;  1WU3 I;  3DI2 A;  5D70 A;  1CN4 C;  4NN6 A;  1YKB A;  4ZF7 A;  1HIJ A;  1IK0 A;  2B91 A;  2JA8 D;  2B8Y A;  5FUC A;  3I4N D;  3SE3 B;  1HWH A;  2R92 D;  1Z92 A;  3SE4 B;  3UX9 A;  1KF9 A;  1FYH A;  4O6K A;  1PGR A;  4GRW A;  2JA6 D;  4A3F D;  2L3Y A;  2XQB A;  3D87 A;  3UEZ E;  1BUY A;  1PVH B;  1BP3 A;  1Y14 A;  5IYB D;  4WRL B;  1BGE A;  1Y1V D;  4DKC A;  2B90 A;  3Q1S I;  1EER A;  1RFB A;  2HYM B;  4NN5 A;  5IP7 D;  2E9W C;  1ITF A;  3BPN A;  2JA7 D;  1M49 A;  3NCC A;  1A7M A;  1AXI A;  1IAR A;  1HIK A;  1EVS A;  3D48 P;  1HUL A;  1ITM A;  4A3B D;  1GA3 A;  4J4L C;  1BGD A;  1M4B A;  3QB1 A;  3N06 A;  1LKI A;  4A3C D;  3HOW D;  2O27 A;  1HGU A;  1RW5 A;  3LB6 B;  3HMX B;  1D9G A;  1WCM D;  3FKI D;  2Z3R A;  4A3I D;  3I4M D;  4BBS D;  3WCY I;  3EJJ A;  1D9C A;  3HHR A;  3DI3 A;  3N0P A;  1JLI A;  1M47 A;  2R7Z D;  1BGC A;  5FLM D;  1N1F A;  3QT2 C;  4MHL A;  4EXN A;  4A3M D;  2VUM D;  1SCF A;  1HWG A;  3B5K A;  4FA8 E;  1ITI A;  1EXZ A;  2PSM A;  3QB7 A;  4O9H A;  5C44 D;  5TS9 A;  1M4R A;  3OG4 A;  5KNH I;  2JA5 D;  1CYL A;  2KZ1 A;  1Y1W D;  5FHX A;  5L6Y C;  2LMS A;  1CSG A;  3VA2 A;  4A3D D;  2O6I A;  3QAZ A;  2OQP A;  3PO2 D;  5D22 A;  5C3E D;  3UF5 A;  4Z5R D;  3L5W I;  4CNI C;  1IRL A;  4A3K D;  5C7X A;  5IYD D;  3AYH A;  3H3V E;  1ALU A;  3G6D A;  1EMR A;  3TGX B;  4BBR D;  4A3L D;  3DUH C;  3BES L;  1B5L A;  1QVN A;  3OG6 A;  3QWR B;  4EXP A;  5LQB A;  1RHG A;  2INT A;  5D28 B;  1LK3 A;  1PW6 A;  5D72 A;  3G9V B;  3INK C;  2B63 D;  4BY1 D;  3DLQ I;  3OQ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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