3HOZD

Complete rna polymerase ii elongation complex iv with a t-u mismatch and a frayed rna 3'-guanine
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
219
structure length
179
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKETREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 42
structure length 179
sequence length 219
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3hozD02
4A3ID 1Y1VD 4A93D 3PO3D 4A3CD 5C44D 4A3BD 4BBSD 3HOUD 1Y14A 4A3KD 3H3VE 2R93D 2C35A 3HOZD 4A3DD 4BY7D 4A3ED 5IYBD 4BXXD 2JA7D 2JA5D 2VUMD 3H0GD 4A3LD 5C4XD 2R92D 1WCMD 2R7ZD 4A3JD 1Y1WD 5IYCD 5IYDD 3HOXD 2JA6D 3FKID 5IP9D 2JA8D 3AYHA 2B63D 4A3GD 3I4ND 5IP7D 3HOWD 5C3ED 4BBRD 3I4MD 5FLMD 4A3MD 3PO2D 4BY1D 3HOVD 4A3FD 3HOYD
chains in the Genus database with same CATH superfamily
2Q14A 4RS1A 3B5KA 1HULA 1M47A 2R93D 1M49A 2B91A 2JA5D 1ETEA 3H0GD 4DKEA 1WU3I 2Y5YA 1F6FA 1LKIA 2H24A 2Z3QA 3SE3B 4LEPA 3PIVA 4U4VA 4GC0A 5L6YC 1RHGA 1Z92A 3DI2A 4YBQA 4YDYI 4PS4A 1BP3A 1Y14A 4LRLA 3NCFA 4JREA 3HMXB 3Q1SI 3MZGA 3EW3A 2R7ZD 1EKUA 3EJJA 5TS9A 5D72A 1AU1A 4GBZA 4UVMA 4D2DA 1BGEA 1EXZA 1Y6NL 3G6DA 1BGDA 1CN4C 3BPNA 1M4RA 4A3LD 5C4XD 4Z5RD 4X51A 4TPHA 4D2CA 4A3JD 2O27A 1HGUA 3QB7A 1F45B 2D48A 3QAZA 2XQBA 1HIJA 1I1RB 1PGRA 4ZF7A 4J4LC 3LB6A 1D9CA 4ZYRA 3QWRB 1BUYA 5KNHI 4O6KA 1Y1WD 1CYLA 3AYHA 1INRA 4YB9D 4PYPA 5EQGA 1YKBA 4GRWA 4NN6A 1HWHA 5FUCA 1JLIA 4OAAA 3QT2C 1ITMA 1FYHA 3G9VB 2CYKA 4BXXD 3WCYI 3DUHC 2B90A 3S9DA 2LAGA 5FHXA 3I4MD 4YPGC 1CD9A 3PO3D 5D59A 4DKDA 1B5LA 5D71A 4GS7A 1BGCA 2O6IA 1EVSA 1P9MB 3HOXD 5IP9D 1BBNA 1Y6KL 2JA8D 2ILKA 1IARA 4QIQA 4ZS7A 3BPOA 2B8UA 4A93D 3IRHA 4A3BD 3UF5A 1ITFA 2B8ZA 1D9GA 2C35A 2O26A 2XUTA 1PV6A 1AX8A 4NKQC 1FG9A 4BBRD 3NCCA 1PV7A 4EXPA 5D28B 1V7MV 4Q65A 1IK0A 2CFPA 3NPZA 4XNJA 3D87A 2Q98A 2KZ1A 3VA2A 2IL6A 4IKWA 4NEMA 2B63D 4JA3A 1IRLA 1LQSL 5C3ED 1PW4A 1A22A 4IU8A 3UEZE 4IKVA 5C44D 1RFBA 3UX9A 1IJZA 1RCBA 1M4BA 5IYDD 4D2BA 1ILKA 1ALUA 1HZIA 3I4ND 2GMFA 3N0PA 4O9HA 1RW5A 1PW6A 5LQBA 2CFQA 1GNCA 1IL6A 3DI3A 4ZWBA 4ZWCA 3WDOA 4A3KD 2INTA 5IYBD 2B8XA 4NN7A 1CSGA 4U4WA 1CNT1 4LDSA 2JA6D 3N06A 3FKID 4GBYA 1Z7CA 4YQXA 3HOYD 3INKC 1AXIA 2L3YA 1Y6ML 3O7PA 1EERA 4BBSD 4NN5A 3H3VE 1N1FA 4A3DD 5C7XA 4A3ED 3NCEA 4MHLA 4IU9A 1SCFA 2L3OA 3L5WI 1LK3A 3BPLA 2D9QA 4TPJA 3HHCA 3PO2D 4A3MD 3OG6A 4A3ID 2V8NA 4A3CD 1M48A 5E4EA 4DKCA 3DLQI 2LMSA 2B5IA 1M4AA 1GA3A 1QVNA 4IKYA 3L5XA 3LB6B 4CNIC 4NI7A 1NBPA 5IP7D 5GXBA 3HOWD 1BCNA 3DGCL 3OG4A 5FLMD 4BY1D 4FA8E 3D85C 1KF9A 1Y1VD 4JR9A 4OH3A 4TPGA 3O7QA 4IKXA 5D70A 4IKZA 3QB1A 5EQIA 1V7NV 5IYCD 2ERJD 2OQPA 1PY2A 2HYMB 4I77Z 4A3FD 3UF2A 1HUWA 4U4TA 1HIKA 4YUEC 4NEJA 1PVHB 3HOUD 3HOZD 4BY7D 4XNIA 2R92D 4WRLB 2PSMA 1J7VL 4APSA 5A2NA 1VLKA 1M4CA 3TGXB 1A7MA 5D22A 2E9WC 2B8YA 5EQHA 5D58A 2JA7D 1HWGA 4DKFA 4W6VA 4A3GD 3SE4B 3D48P 4EXNA 5C65A 1ITLA 2Z3RA 5A2OA 2VUMD 4NI9A 3BESL 3OQ3A 2Q7NB 5D6KA 1WCMD 1ITIA 4DOHA 4ZW9A 4J05A 3NCBA 1EMRA 3HOVD 3PIWA 3HHRA
chains in the Genus database with same CATH topology
3D85C 1JLIA 1KF9A 2Q14A 4RS1A 1Y1VD 3B5KA 3UEZE 1HULA 5C44D 1M47A 1RFBA 3UX9A 1IJZA 1RCBA 3QT2C 2R93D 1ITMA 1FYHA 1M49A 1M4BA 3G9VB 2CYKA 4BXXD 2B91A 5D70A 2JA5D 1ETEA 3H0GD 4DKEA 3QB1A 4BY1D 1V7NV 5IYCD 1WU3I 5IYDD 2ERJD 1ILKA 1F6FA 1ALUA 1HZIA 3WCYI 1LKIA 2OQPA 3DUHC 3I4ND 2GMFA 2H24A 2B90A 2Z3QA 3N0PA 1PY2A 4O9HA 1RW5A 3SE3B 1PW6A 2HYMB 4I77Z 2LAGA 5FHXA 3S9DA 4A3FD 3PIVA 4YPGC 3I4MD 5L6YC 1RHGA 1Z92A 1CD9A 3DI2A 1HUWA 3UF2A 1IL6A 1HIKA 3DI3A 4YUEC 4PS4A 4DKDA 4YDYI 1GNCA 4NEJA 1B5LA 5D71A 1PVHB 1BP3A 1Y14A 2INTA 4GS7A 4LRLA 4A3KD 3HOUD 3NCFA 1BGCA 3HOZD 2O6IA 4BY7D 5IYBD 1EVSA 2B8XA 4NN7A 3HMXB 1CSGA 3Q1SI 3MZGA 4WRLB 2R92D 2PSMA 3EW3A 1CNT1 5LQBA 2R7ZD 1P9MB 1EKUA 3HOXD 3EJJA 5TS9A 3N06A 2JA6D 3FKID 1J7VL 1Z7CA 1BBNA 1Y6KL 5D72A 5IP9D 2JA8D 2ILKA 1IARA 4ZS7A 4YQXA 1AU1A 1VLKA 3BPOA 3HOYD 3INKC 1M4CA 2B8UA 4A93D 1BGEA 3TGXB 1AXIA 2L3YA 1EXZA 1Y6ML 3IRHA 1A7MA 1Y6NL 5D22A 1EERA 4A3BD 4BBSD 3G6DA 3UF5A 4NN5A 3H3VE 1BGDA 1ITFA 1N1FA 2B8ZA 1D9GA 2C35A 1CN4C 4A3DD 3BPNA 2E9WC 5C7XA 4A3ED 2B8YA 3NCEA 1M4RA 2JA7D 4MHLA 4A3LD 2O26A 4Z5RD 5C4XD 4X51A 1HWGA 1SCFA 2L3OA 3L5WI 4DKFA 4A3JD 1LK3A 3BPLA 2D9QA 2O27A 1HGUA 1AX8A 3QB7A 1F45B 4NKQC 4A3GD 1FG9A 2D48A 4BBRD 3HHCA 3SE4B 4A3MD 3PO2D 3NCCA 3QAZA 4EXPA 2XQBA 3OG6A 1HIJA 4A3ID 5D28B 1I1RB 1PGRA 4A3CD 3D48P 1M48A 4ZF7A 5E4EA 1V7MV 4DKCA 4EXNA 3DLQI 1ITLA 4J4LC 2Z3RA 2LMSA 1IK0A 3LB6A 3NPZA 1D9CA 2B5IA 1M4AA 3D87A 1BUYA 3QWRB 2Q98A 1GA3A 1QVNA 2KZ1A 5KNHI 4NI9A 2VUMD 3BESL 3L5XA 3OQ3A 4O6KA 2Q7NB 3PO3D 3LB6B 3VA2A 1WCMD 1Y1WD 1ITIA 2IL6A 1CYLA 4DOHA 4NEMA 3AYHA 3PIWA 4CNIC 2B63D 4NI7A 1INRA 1IRLA 1NBPA 3NCBA 5IP7D 1LQSL 5C3ED 3HOWD 1EMRA 3DGCL 1A22A 1YKBA 3OG4A 5FLMD 1BCNA 4GRWA 4NN6A 4FA8E 3HOVD 1HWHA 3HHRA 5FUCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3I D;  1Y1V D;  4A93 D;  3PO3 D;  4A3C D;  5C44 D;  4A3B D;  4BBS D;  3HOU D;  1Y14 A;  4A3K D;  3H3V E;  2R93 D;  2C35 A;  3HOZ D;  4A3D D;  4BY7 D;  4A3E D;  5IYB D;  4BXX D;  2JA7 D;  2JA5 D;  2VUM D;  3H0G D;  4A3L D;  5C4X D;  2R92 D;  1WCM D;  2R7Z D;  4A3J D;  1Y1W D;  5IYC D;  5IYD D;  3HOX D;  2JA6 D;  3FKI D;  5IP9 D;  2JA8 D;  3AYH A;  2B63 D;  4A3G D;  3I4N D;  5IP7 D;  3HOW D;  5C3E D;  4BBR D;  3I4M D;  5FLM D;  4A3M D;  3PO2 D;  4BY1 D;  3HOV D;  4A3F D;  3HOY D; 
#chains in the Genus database with same CATH topology
 2Q14 A;  4RS1 A;  3B5K A;  1HUL A;  1M47 A;  2R93 D;  1M49 A;  2B91 A;  2JA5 D;  1ETE A;  3H0G D;  4DKE A;  1WU3 I;  2Y5Y A;  1F6F A;  1LKI A;  2H24 A;  2Z3Q A;  3SE3 B;  4LEP A;  3PIV A;  4U4V A;  4GC0 A;  5L6Y C;  1RHG A;  1Z92 A;  3DI2 A;  4YBQ A;  4YDY I;  4PS4 A;  1BP3 A;  1Y14 A;  4LRL A;  3NCF A;  4JRE A;  3HMX B;  3Q1S I;  3MZG A;  3EW3 A;  2R7Z D;  1EKU A;  3EJJ A;  5TS9 A;  5D72 A;  1AU1 A;  4GBZ A;  4UVM A;  4D2D A;  1BGE A;  1EXZ A;  1Y6N L;  3G6D A;  1BGD A;  1CN4 C;  3BPN A;  1M4R A;  4A3L D;  5C4X D;  4Z5R D;  4X51 A;  4TPH A;  4D2C A;  4A3J D;  2O27 A;  1HGU A;  3QB7 A;  1F45 B;  2D48 A;  3QAZ A;  2XQB A;  1HIJ A;  1I1R B;  1PGR A;  4ZF7 A;  4J4L C;  3LB6 A;  1D9C A;  4ZYR A;  3QWR B;  1BUY A;  5KNH I;  4O6K A;  1Y1W D;  1CYL A;  3AYH A;  1INR A;  4YB9 D;  4PYP A;  5EQG A;  1YKB A;  4GRW A;  4NN6 A;  1HWH A;  5FUC A;  1JLI A;  4OAA A;  3QT2 C;  1ITM A;  1FYH A;  3G9V B;  2CYK A;  4BXX D;  3WCY I;  3DUH C;  2B90 A;  3S9D A;  2LAG A;  5FHX A;  3I4M D;  4YPG C;  1CD9 A;  3PO3 D;  5D59 A;  4DKD A;  1B5L A;  5D71 A;  4GS7 A;  1BGC A;  2O6I A;  1EVS A;  1P9M B;  3HOX D;  5IP9 D;  1BBN A;  1Y6K L;  2JA8 D;  2ILK A;  1IAR A;  4QIQ A;  4ZS7 A;  3BPO A;  2B8U A;  4A93 D;  3IRH A;  4A3B D;  3UF5 A;  1ITF A;  2B8Z A;  1D9G A;  2C35 A;  2O26 A;  2XUT A;  1PV6 A;  1AX8 A;  4NKQ C;  1FG9 A;  4BBR D;  3NCC A;  1PV7 A;  4EXP A;  5D28 B;  1V7M V;  4Q65 A;  1IK0 A;  2CFP A;  3NPZ A;  4XNJ A;  3D87 A;  2Q98 A;  2KZ1 A;  3VA2 A;  2IL6 A;  4IKW A;  4NEM A;  2B63 D;  4JA3 A;  1IRL A;  1LQS L;  5C3E D;  1PW4 A;  1A22 A;  4IU8 A;  3UEZ E;  4IKV A;  5C44 D;  1RFB A;  3UX9 A;  1IJZ A;  1RCB A;  1M4B A;  5IYD D;  4D2B A;  1ILK A;  1ALU A;  1HZI A;  3I4N D;  2GMF A;  3N0P A;  4O9H A;  1RW5 A;  1PW6 A;  5LQB A;  2CFQ A;  1GNC A;  1IL6 A;  3DI3 A;  4ZWB A;  4ZWC A;  3WDO A;  4A3K D;  2INT A;  5IYB D;  2B8X A;  4NN7 A;  1CSG A;  4U4W A;  1CNT 1;  4LDS A;  2JA6 D;  3N06 A;  3FKI D;  4GBY A;  1Z7C A;  4YQX A;  3HOY D;  3INK C;  1AXI A;  2L3Y A;  1Y6M L;  3O7P A;  1EER A;  4BBS D;  4NN5 A;  3H3V E;  1N1F A;  4A3D D;  5C7X A;  4A3E D;  3NCE A;  4MHL A;  4IU9 A;  1SCF A;  2L3O A;  3L5W I;  1LK3 A;  3BPL A;  2D9Q A;  4TPJ A;  3HHC A;  3PO2 D;  4A3M D;  3OG6 A;  4A3I D;  2V8N A;  4A3C D;  1M48 A;  5E4E A;  4DKC A;  3DLQ I;  2LMS A;  2B5I A;  1M4A A;  1GA3 A;  1QVN A;  4IKY A;  3L5X A;  3LB6 B;  4CNI C;  4NI7 A;  1NBP A;  5IP7 D;  5GXB A;  3HOW D;  1BCN A;  3DGC L;  3OG4 A;  5FLM D;  4BY1 D;  4FA8 E;  3D85 C;  1KF9 A;  1Y1V D;  4JR9 A;  4OH3 A;  4TPG A;  3O7Q A;  4IKX A;  5D70 A;  4IKZ A;  3QB1 A;  5EQI A;  1V7N V;  5IYC D;  2ERJ D;  2OQP A;  1PY2 A;  2HYM B;  4I77 Z;  4A3F D;  3UF2 A;  1HUW A;  4U4T A;  1HIK A;  4YUE C;  4NEJ A;  1PVH B;  3HOU D;  3HOZ D;  4BY7 D;  4XNI A;  2R92 D;  4WRL B;  2PSM A;  1J7V L;  4APS A;  5A2N A;  1VLK A;  1M4C A;  3TGX B;  1A7M A;  5D22 A;  2E9W C;  2B8Y A;  5EQH A;  5D58 A;  2JA7 D;  1HWG A;  4DKF A;  4W6V A;  4A3G D;  3SE4 B;  3D48 P;  4EXN A;  5C65 A;  1ITL A;  2Z3R A;  5A2O A;  2VUM D;  4NI9 A;  3BES L;  3OQ3 A;  2Q7N B;  5D6K A;  1WCM D;  1ITI A;  4DOH A;  4ZW9 A;  4J05 A;  3NCB A;  1EMR A;  3HOV D;  3PIW A;  3HHR A; 
#chains in the Genus database with same CATH homology
 3D85 C;  1JLI A;  1KF9 A;  2Q14 A;  4RS1 A;  1Y1V D;  3B5K A;  3UEZ E;  1HUL A;  5C44 D;  1M47 A;  1RFB A;  3UX9 A;  1IJZ A;  1RCB A;  3QT2 C;  2R93 D;  1ITM A;  1FYH A;  1M49 A;  1M4B A;  3G9V B;  2CYK A;  4BXX D;  2B91 A;  5D70 A;  2JA5 D;  1ETE A;  3H0G D;  4DKE A;  3QB1 A;  4BY1 D;  1V7N V;  5IYC D;  1WU3 I;  5IYD D;  2ERJ D;  1ILK A;  1F6F A;  1ALU A;  1HZI A;  3WCY I;  1LKI A;  2OQP A;  3DUH C;  3I4N D;  2GMF A;  2H24 A;  2B90 A;  2Z3Q A;  3N0P A;  1PY2 A;  4O9H A;  1RW5 A;  3SE3 B;  1PW6 A;  2HYM B;  4I77 Z;  2LAG A;  5FHX A;  3S9D A;  4A3F D;  3PIV A;  4YPG C;  3I4M D;  5L6Y C;  1RHG A;  1Z92 A;  1CD9 A;  3DI2 A;  1HUW A;  3UF2 A;  1IL6 A;  1HIK A;  3DI3 A;  4YUE C;  4PS4 A;  4DKD A;  4YDY I;  1GNC A;  4NEJ A;  1B5L A;  5D71 A;  1PVH B;  1BP3 A;  1Y14 A;  2INT A;  4GS7 A;  4LRL A;  4A3K D;  3HOU D;  3NCF A;  1BGC A;  3HOZ D;  2O6I A;  4BY7 D;  5IYB D;  1EVS A;  2B8X A;  4NN7 A;  3HMX B;  1CSG A;  3Q1S I;  3MZG A;  4WRL B;  2R92 D;  2PSM A;  3EW3 A;  1CNT 1;  5LQB A;  2R7Z D;  1P9M B;  1EKU A;  3HOX D;  3EJJ A;  5TS9 A;  3N06 A;  2JA6 D;  3FKI D;  1J7V L;  1Z7C A;  1BBN A;  1Y6K L;  5D72 A;  5IP9 D;  2JA8 D;  2ILK A;  1IAR A;  4ZS7 A;  4YQX A;  1AU1 A;  1VLK A;  3BPO A;  3HOY D;  3INK C;  1M4C A;  2B8U A;  4A93 D;  1BGE A;  3TGX B;  1AXI A;  2L3Y A;  1EXZ A;  1Y6M L;  3IRH A;  1A7M A;  1Y6N L;  5D22 A;  1EER A;  4A3B D;  4BBS D;  3G6D A;  3UF5 A;  4NN5 A;  3H3V E;  1BGD A;  1ITF A;  1N1F A;  2B8Z A;  1D9G A;  2C35 A;  1CN4 C;  4A3D D;  3BPN A;  2E9W C;  5C7X A;  4A3E D;  2B8Y A;  3NCE A;  1M4R A;  2JA7 D;  4MHL A;  4A3L D;  2O26 A;  4Z5R D;  5C4X D;  4X51 A;  1HWG A;  1SCF A;  2L3O A;  3L5W I;  4DKF A;  4A3J D;  1LK3 A;  3BPL A;  2D9Q A;  2O27 A;  1HGU A;  1AX8 A;  3QB7 A;  1F45 B;  4NKQ C;  4A3G D;  1FG9 A;  2D48 A;  4BBR D;  3HHC A;  3SE4 B;  4A3M D;  3PO2 D;  3NCC A;  3QAZ A;  4EXP A;  2XQB A;  3OG6 A;  1HIJ A;  4A3I D;  5D28 B;  1I1R B;  1PGR A;  4A3C D;  3D48 P;  1M48 A;  4ZF7 A;  5E4E A;  1V7M V;  4DKC A;  4EXN A;  3DLQ I;  1ITL A;  4J4L C;  2Z3R A;  2LMS A;  1IK0 A;  3LB6 A;  3NPZ A;  1D9C A;  2B5I A;  1M4A A;  3D87 A;  1BUY A;  3QWR B;  2Q98 A;  1GA3 A;  1QVN A;  2KZ1 A;  5KNH I;  4NI9 A;  2VUM D;  3BES L;  3L5X A;  3OQ3 A;  4O6K A;  2Q7N B;  3PO3 D;  3LB6 B;  3VA2 A;  1WCM D;  1Y1W D;  1ITI A;  2IL6 A;  1CYL A;  4DOH A;  4NEM A;  3AYH A;  3PIW A;  4CNI C;  2B63 D;  4NI7 A;  1INR A;  1IRL A;  1NBP A;  3NCB A;  5IP7 D;  1LQS L;  5C3E D;  3HOW D;  1EMR A;  3DGC L;  1A22 A;  1YKB A;  3OG4 A;  5FLM D;  1BCN A;  4GRW A;  4NN6 A;  4FA8 E;  3HOV D;  1HWH A;  3HHR A;  5FUC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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