3OG4A

The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group p21212
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
148
structure length
140
Chain Sequence
SLSPQELASFKKARDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLHHILSQLQACIQPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRDLKYVADGN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1.
pubmed doi rcsb
molecule tags Cytokine/cytokine receptor
source organism Homo sapiens
molecule keywords Interleukin-29
total genus 48
structure length 140
sequence length 148
ec nomenclature
pdb deposition date 2010-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF15177 IL28A Interleukin-28A
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.60 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3og4A00
3OG4A 3OG6A 3HHCA
chains in the Genus database with same CATH superfamily
4NEMA 1BBNA 2E9WC 2D48A 2O26A 2O6IA 4A3ED 1GNCA 1AXIA 5A2NA 4YPGC 4EXPA 4BY1D 1M4CA 1YKBA 4IKXA 3QT2C 4ZF7A 5C65A 1PV7A 4BBRD 1HZIA 1BGEA 1PW6A 1Z92A 4DOHA 4A3BD 4DKCA 2INTA 3IRHA 2O27A 3OG6A 3DLQI 1CNT1 1BGDA 3NCCA 4BBSD 3N0PA 3L5WI 1HGUA 1RCBA 4DKFA 2B8UA 2H24A 3NCEA 1M48A 4NN6A 3UF2A 1D9GA 4I77Z 3DUHC 3HOZD 2JA5D 3N06A 2CFQA 1WCMD 3B5KA 1AX8A 2PSMA 4U4WA 5EQIA 3DI3A 1F6FA 4Q65A 3HOYD 1RHGA 5TS9A 4IKYA 3VA2A 3D85C 3PIWA 2ERJD 5D70A 4LEPA 4YB9D 3NPZA 4U4TA 2OQPA 3UEZE 4ZYRA 4DKDA 2L3YA 3UX9A 4LDSA 4IU8A 4NN5A 2VUMD 5D72A 1B5LA 4WRLB 3D87A 3UF5A 3QAZA 2CFPA 1CN4C 3G6DA 2B8XA 4NKQC 4O6KA 3G9VB 4XNIA 5IP7D 4A3CD 2B5IA 5D28B 3LB6B 1PV6A 4O9HA 4TPGA 3TGXB 1PY2A 1PW4A 4ZS7A 2Q7NB 3I4MD 5LQBA 4D2BA 1ILKA 4GRWA 1Y1WD 1D9CA 3QB7A 1FG9A 2B8ZA 2GMFA 3DGCL 4D2DA 5D58A 2B90A 5C7XA 1Y6ML 1HULA 4ZWBA 1IL6A 1CD9A 1RFBA 2C35A 1V7NV 4A3ID 4D2CA 3MZGA 4PS4A 1IJZA 3O7PA 1HUWA 3I4ND 3EJJA 4YDYI 4J05A 1EMRA 1PGRA 3D48P 4EXNA 1HIJA 5GXBA 3HOXD 3QWRB 4ZWCA 3HMXB 5IYDD 1WU3I 4GBYA 4NEJA 5D71A 3HHRA 1HWHA 1J7VL 3BPOA 5KNHI 5E4EA 4CNIC 1ITLA 2Z3RA 4GBZA 4J4LC 2B63D 3WCYI 3HOUD 4XNJA 1GA3A 2Q98A 1M4AA 4IKVA 1Y1VD 1Y6KL 1BP3A 2B91A 2L3OA 1CSGA 4A3DD 5FHXA 2JA8D 4YBQA 2R93D 3HOWD 5IYBD 3EW3A 3OQ3A 3SE3B 1RW5A 3LB6A 1LKIA 1EXZA 4APSA 5IP9D 5C44D 3H0GD 4A3FD 1V7MV 2R7ZD 5L6YC 3Q1SI 3OG4A 3HHCA 4A3GD 1CYLA 2D9QA 5IYCD 1AU1A 4YQXA 1M4RA 1PVHB 1A22A 4IU9A 1INRA 4PYPA 1LK3A 5EQGA 3PO3D 5FLMD 1M49A 2CYKA 2LAGA 4BY7D 1HWGA 3HOVD 4A3KD 1EKUA 1EVSA 1Z7CA 3INKC 4A3JD 1QVNA 5A2OA 4Z5RD 1M4BA 4NN7A 3QB1A 4QIQA 4YUEC 2Q14A 4NI9A 3L5XA 1JLIA 3AYHA 2HYMB 3DI2A 3PIVA 1IK0A 1ITMA 1IRLA 1VLKA 1NBPA 1FYHA 1F45B 2XUTA 1Y14A 1ETEA 5D6KA 2JA7D 4W6VA 1ITIA 2JA6D 4IKZA 3PO2D 5EQHA 1BGCA 3NCBA 4A3MD 1I1RB 2ILKA 5C4XD 4ZW9A 3SE4B 3WDOA 3O7QA 3FKID 1IARA 4OH3A 4GS7A 1HIKA 4X51A 1ITFA 4DKEA 1EERA 4RS1A 5C3ED 4BXXD 1LQSL 4IKWA 5FUCA 1N1FA 1A7MA 4FA8E 4OAAA 1P9MB 4GC0A 1KF9A 1BCNA 1M47A 4MHLA 1SCFA 2Y5YA 1ALUA 2LMSA 4A3LD 4JR9A 4A93D 4NI7A 3H3VE 3BESL 2V8NA 2Z3QA 3BPNA 3S9DA 1BUYA 2KZ1A 5D22A 1Y6NL 3BPLA 4TPJA 4JREA 4U4VA 2R92D 3NCFA 4TPHA 2B8YA 4JA3A 4UVMA 5D59A 4LRLA 2XQBA 2IL6A
chains in the Genus database with same CATH topology
4NKQC 5E4EA 1IK0A 1ITMA 4NEMA 1BBNA 2E9WC 4CNIC 2D48A 1IRLA 1VLKA 1ITLA 1NBPA 2O26A 2Z3RA 4O6KA 3G9VB 4J4LC 1FYHA 2O6IA 4A3ED 5IP7D 2B63D 1GNCA 3WCYI 1AXIA 1F45B 4A3CD 2B5IA 3HOUD 4YPGC 4EXPA 5D28B 1GA3A 4BY1D 1M4CA 1M4AA 1ETEA 1Y14A 1YKBA 2Q98A 3QT2C 4ZF7A 2JA7D 1Y1VD 3LB6B 1ITIA 2JA6D 3PO2D 4BBRD 1ITFA 1Y6KL 1HZIA 1BGCA 1BGEA 1PW6A 1BP3A 1Z92A 3NCBA 4A3MD 4O9HA 4DOHA 1I1RB 3TGXB 4A3BD 1PY2A 2B91A 4DKCA 2INTA 2ILKA 2L3OA 3IRHA 5C4XD 2O27A 3OG6A 3DLQI 1CSGA 1BGDA 1CNT1 3NCCA 2Q7NB 3SE4B 4ZS7A 3N0PA 5LQBA 4A3DD 4BBSD 5FHXA 3FKID 1ILKA 3L5WI 2JA8D 3HOWD 5IYBD 2R93D 1IARA 4GRWA 4GS7A 1D9CA 1HGUA 3EW3A 1Y1WD 3OQ3A 1HIKA 1RW5A 3LB6A 1FG9A 1LKIA 2B8ZA 1EXZA 3QB7A 4X51A 2GMFA 4DKEA 3DGCL 1EERA 1RCBA 5IP9D 4DKFA 5C44D 3H0GD 4RS1A 1V7MV 5C3ED 5L6YC 2B8UA 4A3FD 3I4MD 2R7ZD 4BXXD 2B90A 2H24A 5C7XA 1LQSL 1Y6ML 3Q1SI 3NCEA 5FUCA 1N1FA 1HULA 1M48A 3OG4A 4NN6A 3HHCA 3UF2A 4A3GD 1D9GA 1IL6A 1CD9A 3DUHC 4I77Z 3SE3B 3HOZD 1RFBA 1A7MA 4FA8E 2JA5D 2C35A 3N06A 1CYLA 2D9QA 1P9MB 5IYCD 1AU1A 1KF9A 1WCMD 1BCNA 1M47A 1M4RA 1PVHB 1A22A 1V7NV 3B5KA 4MHLA 4YQXA 1INRA 1AX8A 2PSMA 1SCFA 4A3ID 1LK3A 3MZGA 4PS4A 3PO3D 1ALUA 1IJZA 3DI3A 1F6FA 2LMSA 3HOYD 4A3LD 5FLMD 1RHGA 5TS9A 1M49A 2CYKA 1HUWA 3VA2A 3D85C 3I4ND 2LAGA 3PIWA 1HWGA 2ERJD 5D70A 4A93D 3HOVD 4A3KD 4BY7D 1EKUA 3EJJA 1EVSA 4NI7A 3H3VE 3NPZA 1Z7CA 4YDYI 3BESL 1EMRA 3INKC 2OQPA 3UEZE 2Z3QA 4A3JD 1QVNA 4DKDA 1PGRA 2L3YA 3BPNA 3S9DA 1BUYA 2KZ1A 5D22A 3D48P 3UX9A 4EXNA 1Y6NL 4Z5RD 1HIJA 4NN5A 3HOXD 1M4BA 4NN7A 2VUMD 3BPLA 3QB1A 5D72A 3QWRB 1B5LA 4WRLB 4YUEC 2R92D 3NCFA 2Q14A 3HMXB 3D87A 3UF5A 5IYDD 4NI9A 1WU3I 3QAZA 3L5XA 2B8YA 4NEJA 5D71A 1JLIA 3AYHA 1CN4C 3G6DA 2HYMB 3HHRA 1HWHA 3DI2A 1J7VL 3PIVA 3BPOA 4LRLA 2XQBA 5KNHI 2IL6A 2B8XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OG4 A;  3OG6 A;  3HHC A; 
#chains in the Genus database with same CATH topology
 4NEM A;  1BBN A;  2E9W C;  2D48 A;  2O26 A;  2O6I A;  4A3E D;  1GNC A;  1AXI A;  5A2N A;  4YPG C;  4EXP A;  4BY1 D;  1M4C A;  1YKB A;  4IKX A;  3QT2 C;  4ZF7 A;  5C65 A;  1PV7 A;  4BBR D;  1HZI A;  1BGE A;  1PW6 A;  1Z92 A;  4DOH A;  4A3B D;  4DKC A;  2INT A;  3IRH A;  2O27 A;  3OG6 A;  3DLQ I;  1CNT 1;  1BGD A;  3NCC A;  4BBS D;  3N0P A;  3L5W I;  1HGU A;  1RCB A;  4DKF A;  2B8U A;  2H24 A;  3NCE A;  1M48 A;  4NN6 A;  3UF2 A;  1D9G A;  4I77 Z;  3DUH C;  3HOZ D;  2JA5 D;  3N06 A;  2CFQ A;  1WCM D;  3B5K A;  1AX8 A;  2PSM A;  4U4W A;  5EQI A;  3DI3 A;  1F6F A;  4Q65 A;  3HOY D;  1RHG A;  5TS9 A;  4IKY A;  3VA2 A;  3D85 C;  3PIW A;  2ERJ D;  5D70 A;  4LEP A;  4YB9 D;  3NPZ A;  4U4T A;  2OQP A;  3UEZ E;  4ZYR A;  4DKD A;  2L3Y A;  3UX9 A;  4LDS A;  4IU8 A;  4NN5 A;  2VUM D;  5D72 A;  1B5L A;  4WRL B;  3D87 A;  3UF5 A;  3QAZ A;  2CFP A;  1CN4 C;  3G6D A;  2B8X A;  4NKQ C;  4O6K A;  3G9V B;  4XNI A;  5IP7 D;  4A3C D;  2B5I A;  5D28 B;  3LB6 B;  1PV6 A;  4O9H A;  4TPG A;  3TGX B;  1PY2 A;  1PW4 A;  4ZS7 A;  2Q7N B;  3I4M D;  5LQB A;  4D2B A;  1ILK A;  4GRW A;  1Y1W D;  1D9C A;  3QB7 A;  1FG9 A;  2B8Z A;  2GMF A;  3DGC L;  4D2D A;  5D58 A;  2B90 A;  5C7X A;  1Y6M L;  1HUL A;  4ZWB A;  1IL6 A;  1CD9 A;  1RFB A;  2C35 A;  1V7N V;  4A3I D;  4D2C A;  3MZG A;  4PS4 A;  1IJZ A;  3O7P A;  1HUW A;  3I4N D;  3EJJ A;  4YDY I;  4J05 A;  1EMR A;  1PGR A;  3D48 P;  4EXN A;  1HIJ A;  5GXB A;  3HOX D;  3QWR B;  4ZWC A;  3HMX B;  5IYD D;  1WU3 I;  4GBY A;  4NEJ A;  5D71 A;  3HHR A;  1HWH A;  1J7V L;  3BPO A;  5KNH I;  5E4E A;  4CNI C;  1ITL A;  2Z3R A;  4GBZ A;  4J4L C;  2B63 D;  3WCY I;  3HOU D;  4XNJ A;  1GA3 A;  2Q98 A;  1M4A A;  4IKV A;  1Y1V D;  1Y6K L;  1BP3 A;  2B91 A;  2L3O A;  1CSG A;  4A3D D;  5FHX A;  2JA8 D;  4YBQ A;  2R93 D;  3HOW D;  5IYB D;  3EW3 A;  3OQ3 A;  3SE3 B;  1RW5 A;  3LB6 A;  1LKI A;  1EXZ A;  4APS A;  5IP9 D;  5C44 D;  3H0G D;  4A3F D;  1V7M V;  2R7Z D;  5L6Y C;  3Q1S I;  3OG4 A;  3HHC A;  4A3G D;  1CYL A;  2D9Q A;  5IYC D;  1AU1 A;  4YQX A;  1M4R A;  1PVH B;  1A22 A;  4IU9 A;  1INR A;  4PYP A;  1LK3 A;  5EQG A;  3PO3 D;  5FLM D;  1M49 A;  2CYK A;  2LAG A;  4BY7 D;  1HWG A;  3HOV D;  4A3K D;  1EKU A;  1EVS A;  1Z7C A;  3INK C;  4A3J D;  1QVN A;  5A2O A;  4Z5R D;  1M4B A;  4NN7 A;  3QB1 A;  4QIQ A;  4YUE C;  2Q14 A;  4NI9 A;  3L5X A;  1JLI A;  3AYH A;  2HYM B;  3DI2 A;  3PIV A;  1IK0 A;  1ITM A;  1IRL A;  1VLK A;  1NBP A;  1FYH A;  1F45 B;  2XUT A;  1Y14 A;  1ETE A;  5D6K A;  2JA7 D;  4W6V A;  1ITI A;  2JA6 D;  4IKZ A;  3PO2 D;  5EQH A;  1BGC A;  3NCB A;  4A3M D;  1I1R B;  2ILK A;  5C4X D;  4ZW9 A;  3SE4 B;  3WDO A;  3O7Q A;  3FKI D;  1IAR A;  4OH3 A;  4GS7 A;  1HIK A;  4X51 A;  1ITF A;  4DKE A;  1EER A;  4RS1 A;  5C3E D;  4BXX D;  1LQS L;  4IKW A;  5FUC A;  1N1F A;  1A7M A;  4FA8 E;  4OAA A;  1P9M B;  4GC0 A;  1KF9 A;  1BCN A;  1M47 A;  4MHL A;  1SCF A;  2Y5Y A;  1ALU A;  2LMS A;  4A3L D;  4JR9 A;  4A93 D;  4NI7 A;  3H3V E;  3BES L;  2V8N A;  2Z3Q A;  3BPN A;  3S9D A;  1BUY A;  2KZ1 A;  5D22 A;  1Y6N L;  3BPL A;  4TPJ A;  4JRE A;  4U4V A;  2R92 D;  3NCF A;  4TPH A;  2B8Y A;  4JA3 A;  4UVM A;  5D59 A;  4LRL A;  2XQB A;  2IL6 A; 
#chains in the Genus database with same CATH homology
 4NKQ C;  5E4E A;  1IK0 A;  1ITM A;  4NEM A;  1BBN A;  2E9W C;  4CNI C;  2D48 A;  1IRL A;  1VLK A;  1ITL A;  1NBP A;  2O26 A;  2Z3R A;  4O6K A;  3G9V B;  4J4L C;  1FYH A;  2O6I A;  4A3E D;  5IP7 D;  2B63 D;  1GNC A;  3WCY I;  1AXI A;  1F45 B;  4A3C D;  2B5I A;  3HOU D;  4YPG C;  4EXP A;  5D28 B;  1GA3 A;  4BY1 D;  1M4C A;  1M4A A;  1ETE A;  1Y14 A;  1YKB A;  2Q98 A;  3QT2 C;  4ZF7 A;  2JA7 D;  1Y1V D;  3LB6 B;  1ITI A;  2JA6 D;  3PO2 D;  4BBR D;  1ITF A;  1Y6K L;  1HZI A;  1BGC A;  1BGE A;  1PW6 A;  1BP3 A;  1Z92 A;  3NCB A;  4A3M D;  4O9H A;  4DOH A;  1I1R B;  3TGX B;  4A3B D;  1PY2 A;  2B91 A;  4DKC A;  2INT A;  2ILK A;  2L3O A;  3IRH A;  5C4X D;  2O27 A;  3OG6 A;  3DLQ I;  1CSG A;  1BGD A;  1CNT 1;  3NCC A;  2Q7N B;  3SE4 B;  4ZS7 A;  3N0P A;  5LQB A;  4A3D D;  4BBS D;  5FHX A;  3FKI D;  1ILK A;  3L5W I;  2JA8 D;  3HOW D;  5IYB D;  2R93 D;  1IAR A;  4GRW A;  4GS7 A;  1D9C A;  1HGU A;  3EW3 A;  1Y1W D;  3OQ3 A;  1HIK A;  1RW5 A;  3LB6 A;  1FG9 A;  1LKI A;  2B8Z A;  1EXZ A;  3QB7 A;  4X51 A;  2GMF A;  4DKE A;  3DGC L;  1EER A;  1RCB A;  5IP9 D;  4DKF A;  5C44 D;  3H0G D;  4RS1 A;  1V7M V;  5C3E D;  5L6Y C;  2B8U A;  4A3F D;  3I4M D;  2R7Z D;  4BXX D;  2B90 A;  2H24 A;  5C7X A;  1LQS L;  1Y6M L;  3Q1S I;  3NCE A;  5FUC A;  1N1F A;  1HUL A;  1M48 A;  3OG4 A;  4NN6 A;  3HHC A;  3UF2 A;  4A3G D;  1D9G A;  1IL6 A;  1CD9 A;  3DUH C;  4I77 Z;  3SE3 B;  3HOZ D;  1RFB A;  1A7M A;  4FA8 E;  2JA5 D;  2C35 A;  3N06 A;  1CYL A;  2D9Q A;  1P9M B;  5IYC D;  1AU1 A;  1KF9 A;  1WCM D;  1BCN A;  1M47 A;  1M4R A;  1PVH B;  1A22 A;  1V7N V;  3B5K A;  4MHL A;  4YQX A;  1INR A;  1AX8 A;  2PSM A;  1SCF A;  4A3I D;  1LK3 A;  3MZG A;  4PS4 A;  3PO3 D;  1ALU A;  1IJZ A;  3DI3 A;  1F6F A;  2LMS A;  3HOY D;  4A3L D;  5FLM D;  1RHG A;  5TS9 A;  1M49 A;  2CYK A;  1HUW A;  3VA2 A;  3D85 C;  3I4N D;  2LAG A;  3PIW A;  1HWG A;  2ERJ D;  5D70 A;  4A93 D;  3HOV D;  4A3K D;  4BY7 D;  1EKU A;  3EJJ A;  1EVS A;  4NI7 A;  3H3V E;  3NPZ A;  1Z7C A;  4YDY I;  3BES L;  1EMR A;  3INK C;  2OQP A;  3UEZ E;  2Z3Q A;  4A3J D;  1QVN A;  4DKD A;  1PGR A;  2L3Y A;  3BPN A;  3S9D A;  1BUY A;  2KZ1 A;  5D22 A;  3D48 P;  3UX9 A;  4EXN A;  1Y6N L;  4Z5R D;  1HIJ A;  4NN5 A;  3HOX D;  1M4B A;  4NN7 A;  2VUM D;  3BPL A;  3QB1 A;  5D72 A;  3QWR B;  1B5L A;  4WRL B;  4YUE C;  2R92 D;  3NCF A;  2Q14 A;  3HMX B;  3D87 A;  3UF5 A;  5IYD D;  4NI9 A;  1WU3 I;  3QAZ A;  3L5X A;  2B8Y A;  4NEJ A;  5D71 A;  1JLI A;  3AYH A;  1CN4 C;  3G6D A;  2HYM B;  3HHR A;  1HWH A;  3DI2 A;  1J7V L;  3PIV A;  3BPO A;  4LRL A;  2XQB A;  5KNH I;  2IL6 A;  2B8X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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