3OG6A

The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group p212121
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
149
structure length
143
Chain Sequence
SLSPQELASFKKARDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLHHILSQLQACIQPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRDLKYVADGNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1.
pubmed doi rcsb
molecule tags Cytokine/cytokine receptor
source organism Homo sapiens
molecule keywords Interleukin-29
total genus 52
structure length 143
sequence length 149
ec nomenclature
pdb deposition date 2010-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF15177 IL28A Interleukin-28A
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.60 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 3og6A00
3OG6A 3HHCA 3OG4A
chains in the Genus database with same CATH superfamily
1BGCA 5D71A 4TPHA 3O7PA 5D22A 2H24A 2ERJD 4ZF7A 1HZIA 1GA3A 1PW6A 2Q7NB 2L3YA 1ITLA 3I4MD 3QB1A 4LDSA 3BPNA 4JREA 1ILKA 1CYLA 1LK3A 3SE4B 2R7ZD 1CSGA 3OG4A 2B90A 2Q14A 1AXIA 4A3ID 4GBYA 5IYDD 3LB6B 1Z92A 1KF9A 3QWRB 2V8NA 4A3CD 1EMRA 1HIJA 4JA3A 4YBQA 2O6IA 1PV6A 4JR9A 1M47A 4D2DA 5D6KA 5C3ED 5C7XA 2O27A 4UVMA 4RS1A 1A22A 1F6FA 4BY7D 3WDOA 5E4EA 3PO2D 1AU1A 3NCBA 4A3KD 4BBSD 4X51A 4YQXA 2IL6A 2XUTA 5IP9D 3NCCA 1ITIA 1V7NV 1EERA 3N06A 1M48A 4IKXA 4A93D 4ZS7A 3FKID 4IU9A 4U4VA 4YUEC 3HOXD 2HYMB 4EXPA 2Z3QA 1Y14A 3IRHA 5TS9A 4O6KA 1D9CA 4YB9D 4NEMA 2LMSA 2CYKA 2B8ZA 4MHLA 4BXXD 4EXNA 1M4RA 4IKWA 1M4BA 5EQGA 5EQHA 3HHCA 3G9VB 5IYCD 1Y6ML 2INTA 1BBNA 1HWGA 4IU8A 4A3JD 2B91A 4NN5A 5IP7D 1WU3I 3DI3A 5FHXA 4NI7A 2E9WC 4ZYRA 2B8UA 4CNIC 4A3LD 1BGEA 4IKVA 4A3DD 1PVHB 3PIWA 3UEZE 5D58A 4APSA 3OG6A 1HGUA 1EKUA 4TPJA 3HOYD 4XNIA 1HIKA 5LQBA 4LRLA 4WRLB 3UF5A 1INRA 2R92D 1AX8A 3H0GD 2CFQA 4PS4A 3DUHC 1RW5A 3PIVA 4NI9A 4IKYA 2KZ1A 1ITFA 2Z3RA 1B5LA 4ZWBA 1BUYA 1WCMD 3QAZA 2Q98A 2CFPA 2B8XA 5C4XD 5EQIA 2JA5D 2PSMA 3D87A 4BBRD 1Y1WD 1NBPA 1RHGA 4ZW9A 1BGDA 5A2OA 3D85C 1IJZA 3NPZA 2L3OA 2C35A 1LKIA 1ALUA 3SE3B 1M4AA 3N0PA 3QT2C 3INKC 5D59A 5D72A 2O26A 5FUCA 2D48A 1M4CA 3HHRA 1CNT1 3TGXB 1SCFA 3BPOA 5D70A 4NN7A 1EVSA 1HULA 3DGCL 5FLMD 4D2CA 3HOZD 4GRWA 3L5XA 2JA7D 1Y1VD 5C65A 5IYBD 3H3VE 3QB7A 1RFBA 1QVNA 2R93D 1PW4A 4NN6A 2B5IA 1HWHA 4Z5RD 3MZGA 4XNJA 3HOUD 4DKFA 5L6YC 1ITMA 1I1RB 1FG9A 4PYPA 1A7MA 3O7QA 3UF2A 4GC0A 1BCNA 4NKQC 4FA8E 3PO3D 2GMFA 3EJJA 1J7VL 1V7MV 3S9DA 4W6VA 3G6DA 4QIQA 1PY2A 2D9QA 4Q65A 1Y6KL 2VUMD 3BPLA 4BY1D 4YDYI 1IK0A 1F45B 1Z7CA 4A3MD 1Y6NL 4D2BA 1M49A 3I4ND 4ZWCA 4GBZA 4U4TA 4NEJA 2LAGA 4I77Z 4DKEA 5A2NA 1CN4C 1FYHA 4LEPA 5D28B 1LQSL 3HOVD 3WCYI 5GXBA 5C44D 1CD9A 4U4WA 3BESL 1ETEA 1JLIA 3Q1SI 5KNHI 4TPGA 3L5WI 1IARA 3HMXB 4OH3A 3EW3A 2B63D 1EXZA 1BP3A 1RCBA 3D48P 4DKDA 1PGRA 1YKBA 3HOWD 4J05A 3VA2A 4DKCA 1N1FA 3AYHA 4J4LC 2Y5YA 3B5KA 2JA8D 3DLQI 4A3GD 1IL6A 4A3ED 4YPGC 4DOHA 1HUWA 2B8YA 2JA6D 2OQPA 2XQBA 1D9GA 4OAAA 1GNCA 3DI2A 3OQ3A 3NCFA 4A3BD 4O9HA 4GS7A 1PV7A 1VLKA 4IKZA 3UX9A 1P9MB 3NCEA 1IRLA 4A3FD 2ILKA 3LB6A
chains in the Genus database with same CATH topology
1Z7CA 4A3MD 1Y6NL 2L3OA 1BGCA 5D71A 1M49A 2CYKA 2B8ZA 2C35A 1LKIA 4MHLA 4BXXD 4EXNA 1ALUA 3SE3B 1M4RA 1M4AA 1M4BA 3I4ND 4NEMA 3N0PA 3HHCA 3G9VB 3QT2C 5D22A 2H24A 3INKC 5IYCD 4NEJA 2ERJD 5D72A 1Y6ML 2INTA 1HZIA 4ZF7A 1GA3A 2LAGA 2O26A 5FUCA 1PW6A 2D48A 1M4CA 1BBNA 1CNT1 3HHRA 2Q7NB 4I77Z 3TGXB 1HWGA 1SCFA 4DKEA 3BPOA 5D70A 2L3YA 1CN4C 4A3JD 1FYHA 4NN7A 1ITLA 1EVSA 3I4MD 1HULA 2B91A 4NN5A 3DGCL 5D28B 1WU3I 1LQSL 3QB1A 5IP7D 5FLMD 3DI3A 5FHXA 3BPNA 4NI7A 3HOZD 2E9WC 1ILKA 2B8UA 4GRWA 1LK3A 3SE4B 1CYLA 3L5XA 4CNIC 3HOVD 2JA7D 4A3LD 1Y1VD 3WCYI 1BGEA 5C44D 4A3DD 1CD9A 1PVHB 3BESL 5IYBD 3H3VE 2R7ZD 3PIWA 3UEZE 1ETEA 1JLIA 3OG6A 3QB7A 1CSGA 1EKUA 1HGUA 1QVNA 1RFBA 3OG4A 3Q1SI 5KNHI 2R93D 2B90A 3HOYD 1HIKA 2Q14A 1AXIA 3L5WI 5LQBA 1IARA 3HMXB 4LRLA 4WRLB 3UF5A 5IYDD 1INRA 4A3ID 3LB6B 3EW3A 1Z92A 1KF9A 3QWRB 2R92D 1EXZA 1AX8A 1BP3A 4NN6A 2B63D 1RCBA 3D48P 4A3CD 1EMRA 1HIJA 2B5IA 1HWHA 1PGRA 3H0GD 4DKDA 1YKBA 2O6IA 3HOWD 1M47A 4Z5RD 3MZGA 3VA2A 4DKCA 5C3ED 4PS4A 1N1FA 5C7XA 2O27A 3AYHA 3B5KA 4J4LC 3HOUD 2JA8D 4DKFA 5L6YC 1IK0A 1ITMA 3DUHC 1I1RB 1A22A 4RS1A 1FG9A 3DLQI 1F6FA 1RW5A 3PIVA 4BY7D 4A3GD 1IL6A 5E4EA 4A3ED 1A7MA 4NI9A 3PO2D 4YPGC 4DOHA 2KZ1A 1AU1A 1HUWA 3NCBA 4A3KD 4BBSD 3NPZA 1ITFA 2Z3RA 4X51A 4YQXA 1B5LA 2IL6A 5IP9D 3NCCA 1ITIA 2B8YA 1V7NV 1BUYA 2JA6D 3UF2A 1EERA 1WCMD 2OQPA 2Q98A 2XQBA 3N06A 3QAZA 4NKQC 1D9GA 4FA8E 1BCNA 1M48A 1GNCA 2B8XA 4A93D 3PO3D 2GMFA 5C4XD 3DI2A 3OQ3A 3EJJA 1J7VL 4ZS7A 2JA5D 1V7MV 2PSMA 3D87A 3NCFA 3S9DA 3G6DA 4BBRD 1Y1WD 4A3BD 1NBPA 3FKID 4O9HA 4GS7A 1PY2A 4YUEC 1VLKA 3HOXD 1RHGA 2D9QA 2HYMB 4EXPA 3UX9A 1P9MB 1BGDA 2Z3QA 1Y14A 3NCEA 1IRLA 1Y6KL 2VUMD 3BPLA 3IRHA 3D85C 5TS9A 4A3FD 4O6KA 1D9CA 1IJZA 2ILKA 3LB6A 2LMSA 4BY1D 4YDYI 1F45B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OG6 A;  3HHC A;  3OG4 A; 
#chains in the Genus database with same CATH topology
 1BGC A;  5D71 A;  4TPH A;  3O7P A;  5D22 A;  2H24 A;  2ERJ D;  4ZF7 A;  1HZI A;  1GA3 A;  1PW6 A;  2Q7N B;  2L3Y A;  1ITL A;  3I4M D;  3QB1 A;  4LDS A;  3BPN A;  4JRE A;  1ILK A;  1CYL A;  1LK3 A;  3SE4 B;  2R7Z D;  1CSG A;  3OG4 A;  2B90 A;  2Q14 A;  1AXI A;  4A3I D;  4GBY A;  5IYD D;  3LB6 B;  1Z92 A;  1KF9 A;  3QWR B;  2V8N A;  4A3C D;  1EMR A;  1HIJ A;  4JA3 A;  4YBQ A;  2O6I A;  1PV6 A;  4JR9 A;  1M47 A;  4D2D A;  5D6K A;  5C3E D;  5C7X A;  2O27 A;  4UVM A;  4RS1 A;  1A22 A;  1F6F A;  4BY7 D;  3WDO A;  5E4E A;  3PO2 D;  1AU1 A;  3NCB A;  4A3K D;  4BBS D;  4X51 A;  4YQX A;  2IL6 A;  2XUT A;  5IP9 D;  3NCC A;  1ITI A;  1V7N V;  1EER A;  3N06 A;  1M48 A;  4IKX A;  4A93 D;  4ZS7 A;  3FKI D;  4IU9 A;  4U4V A;  4YUE C;  3HOX D;  2HYM B;  4EXP A;  2Z3Q A;  1Y14 A;  3IRH A;  5TS9 A;  4O6K A;  1D9C A;  4YB9 D;  4NEM A;  2LMS A;  2CYK A;  2B8Z A;  4MHL A;  4BXX D;  4EXN A;  1M4R A;  4IKW A;  1M4B A;  5EQG A;  5EQH A;  3HHC A;  3G9V B;  5IYC D;  1Y6M L;  2INT A;  1BBN A;  1HWG A;  4IU8 A;  4A3J D;  2B91 A;  4NN5 A;  5IP7 D;  1WU3 I;  3DI3 A;  5FHX A;  4NI7 A;  2E9W C;  4ZYR A;  2B8U A;  4CNI C;  4A3L D;  1BGE A;  4IKV A;  4A3D D;  1PVH B;  3PIW A;  3UEZ E;  5D58 A;  4APS A;  3OG6 A;  1HGU A;  1EKU A;  4TPJ A;  3HOY D;  4XNI A;  1HIK A;  5LQB A;  4LRL A;  4WRL B;  3UF5 A;  1INR A;  2R92 D;  1AX8 A;  3H0G D;  2CFQ A;  4PS4 A;  3DUH C;  1RW5 A;  3PIV A;  4NI9 A;  4IKY A;  2KZ1 A;  1ITF A;  2Z3R A;  1B5L A;  4ZWB A;  1BUY A;  1WCM D;  3QAZ A;  2Q98 A;  2CFP A;  2B8X A;  5C4X D;  5EQI A;  2JA5 D;  2PSM A;  3D87 A;  4BBR D;  1Y1W D;  1NBP A;  1RHG A;  4ZW9 A;  1BGD A;  5A2O A;  3D85 C;  1IJZ A;  3NPZ A;  2L3O A;  2C35 A;  1LKI A;  1ALU A;  3SE3 B;  1M4A A;  3N0P A;  3QT2 C;  3INK C;  5D59 A;  5D72 A;  2O26 A;  5FUC A;  2D48 A;  1M4C A;  3HHR A;  1CNT 1;  3TGX B;  1SCF A;  3BPO A;  5D70 A;  4NN7 A;  1EVS A;  1HUL A;  3DGC L;  5FLM D;  4D2C A;  3HOZ D;  4GRW A;  3L5X A;  2JA7 D;  1Y1V D;  5C65 A;  5IYB D;  3H3V E;  3QB7 A;  1RFB A;  1QVN A;  2R93 D;  1PW4 A;  4NN6 A;  2B5I A;  1HWH A;  4Z5R D;  3MZG A;  4XNJ A;  3HOU D;  4DKF A;  5L6Y C;  1ITM A;  1I1R B;  1FG9 A;  4PYP A;  1A7M A;  3O7Q A;  3UF2 A;  4GC0 A;  1BCN A;  4NKQ C;  4FA8 E;  3PO3 D;  2GMF A;  3EJJ A;  1J7V L;  1V7M V;  3S9D A;  4W6V A;  3G6D A;  4QIQ A;  1PY2 A;  2D9Q A;  4Q65 A;  1Y6K L;  2VUM D;  3BPL A;  4BY1 D;  4YDY I;  1IK0 A;  1F45 B;  1Z7C A;  4A3M D;  1Y6N L;  4D2B A;  1M49 A;  3I4N D;  4ZWC A;  4GBZ A;  4U4T A;  4NEJ A;  2LAG A;  4I77 Z;  4DKE A;  5A2N A;  1CN4 C;  1FYH A;  4LEP A;  5D28 B;  1LQS L;  3HOV D;  3WCY I;  5GXB A;  5C44 D;  1CD9 A;  4U4W A;  3BES L;  1ETE A;  1JLI A;  3Q1S I;  5KNH I;  4TPG A;  3L5W I;  1IAR A;  3HMX B;  4OH3 A;  3EW3 A;  2B63 D;  1EXZ A;  1BP3 A;  1RCB A;  3D48 P;  4DKD A;  1PGR A;  1YKB A;  3HOW D;  4J05 A;  3VA2 A;  4DKC A;  1N1F A;  3AYH A;  4J4L C;  2Y5Y A;  3B5K A;  2JA8 D;  3DLQ I;  4A3G D;  1IL6 A;  4A3E D;  4YPG C;  4DOH A;  1HUW A;  2B8Y A;  2JA6 D;  2OQP A;  2XQB A;  1D9G A;  4OAA A;  1GNC A;  3DI2 A;  3OQ3 A;  3NCF A;  4A3B D;  4O9H A;  4GS7 A;  1PV7 A;  1VLK A;  4IKZ A;  3UX9 A;  1P9M B;  3NCE A;  1IRL A;  4A3F D;  2ILK A;  3LB6 A; 
#chains in the Genus database with same CATH homology
 1Z7C A;  4A3M D;  1Y6N L;  2L3O A;  1BGC A;  5D71 A;  1M49 A;  2CYK A;  2B8Z A;  2C35 A;  1LKI A;  4MHL A;  4BXX D;  4EXN A;  1ALU A;  3SE3 B;  1M4R A;  1M4A A;  1M4B A;  3I4N D;  4NEM A;  3N0P A;  3HHC A;  3G9V B;  3QT2 C;  5D22 A;  2H24 A;  3INK C;  5IYC D;  4NEJ A;  2ERJ D;  5D72 A;  1Y6M L;  2INT A;  1HZI A;  4ZF7 A;  1GA3 A;  2LAG A;  2O26 A;  5FUC A;  1PW6 A;  2D48 A;  1M4C A;  1BBN A;  1CNT 1;  3HHR A;  2Q7N B;  4I77 Z;  3TGX B;  1HWG A;  1SCF A;  4DKE A;  3BPO A;  5D70 A;  2L3Y A;  1CN4 C;  4A3J D;  1FYH A;  4NN7 A;  1ITL A;  1EVS A;  3I4M D;  1HUL A;  2B91 A;  4NN5 A;  3DGC L;  5D28 B;  1WU3 I;  1LQS L;  3QB1 A;  5IP7 D;  5FLM D;  3DI3 A;  5FHX A;  3BPN A;  4NI7 A;  3HOZ D;  2E9W C;  1ILK A;  2B8U A;  4GRW A;  1LK3 A;  3SE4 B;  1CYL A;  3L5X A;  4CNI C;  3HOV D;  2JA7 D;  4A3L D;  1Y1V D;  3WCY I;  1BGE A;  5C44 D;  4A3D D;  1CD9 A;  1PVH B;  3BES L;  5IYB D;  3H3V E;  2R7Z D;  3PIW A;  3UEZ E;  1ETE A;  1JLI A;  3OG6 A;  3QB7 A;  1CSG A;  1EKU A;  1HGU A;  1QVN A;  1RFB A;  3OG4 A;  3Q1S I;  5KNH I;  2R93 D;  2B90 A;  3HOY D;  1HIK A;  2Q14 A;  1AXI A;  3L5W I;  5LQB A;  1IAR A;  3HMX B;  4LRL A;  4WRL B;  3UF5 A;  5IYD D;  1INR A;  4A3I D;  3LB6 B;  3EW3 A;  1Z92 A;  1KF9 A;  3QWR B;  2R92 D;  1EXZ A;  1AX8 A;  1BP3 A;  4NN6 A;  2B63 D;  1RCB A;  3D48 P;  4A3C D;  1EMR A;  1HIJ A;  2B5I A;  1HWH A;  1PGR A;  3H0G D;  4DKD A;  1YKB A;  2O6I A;  3HOW D;  1M47 A;  4Z5R D;  3MZG A;  3VA2 A;  4DKC A;  5C3E D;  4PS4 A;  1N1F A;  5C7X A;  2O27 A;  3AYH A;  3B5K A;  4J4L C;  3HOU D;  2JA8 D;  4DKF A;  5L6Y C;  1IK0 A;  1ITM A;  3DUH C;  1I1R B;  1A22 A;  4RS1 A;  1FG9 A;  3DLQ I;  1F6F A;  1RW5 A;  3PIV A;  4BY7 D;  4A3G D;  1IL6 A;  5E4E A;  4A3E D;  1A7M A;  4NI9 A;  3PO2 D;  4YPG C;  4DOH A;  2KZ1 A;  1AU1 A;  1HUW A;  3NCB A;  4A3K D;  4BBS D;  3NPZ A;  1ITF A;  2Z3R A;  4X51 A;  4YQX A;  1B5L A;  2IL6 A;  5IP9 D;  3NCC A;  1ITI A;  2B8Y A;  1V7N V;  1BUY A;  2JA6 D;  3UF2 A;  1EER A;  1WCM D;  2OQP A;  2Q98 A;  2XQB A;  3N06 A;  3QAZ A;  4NKQ C;  1D9G A;  4FA8 E;  1BCN A;  1M48 A;  1GNC A;  2B8X A;  4A93 D;  3PO3 D;  2GMF A;  5C4X D;  3DI2 A;  3OQ3 A;  3EJJ A;  1J7V L;  4ZS7 A;  2JA5 D;  1V7M V;  2PSM A;  3D87 A;  3NCF A;  3S9D A;  3G6D A;  4BBR D;  1Y1W D;  4A3B D;  1NBP A;  3FKI D;  4O9H A;  4GS7 A;  1PY2 A;  4YUE C;  1VLK A;  3HOX D;  1RHG A;  2D9Q A;  2HYM B;  4EXP A;  3UX9 A;  1P9M B;  1BGD A;  2Z3Q A;  1Y14 A;  3NCE A;  1IRL A;  1Y6K L;  2VUM D;  3BPL A;  3IRH A;  3D85 C;  5TS9 A;  4A3F D;  4O6K A;  1D9C A;  1IJZ A;  2ILK A;  3LB6 A;  2LMS A;  4BY1 D;  4YDY I;  1F45 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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