3PO2 | Genus

Total Genus 61

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	61
sequence length	221
structure length	180
Chain Sequence	MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase/dna/rna
publication title	Structural basis of RNA polymerase II backtracking, arrest and reactivation. pubmed doi rcsb
molecule keywords	DNA-directed RNA polymerase II subunit RPB1
total genus	61
structure length	180
sequence length	221
ec nomenclature
pdb deposition date	2010-11-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
D	PF03874	RNA_pol_Rpb4	RNA polymerase Rpb4

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.1250.40	Mainly Alpha	Up-down Bundle	Growth Hormone; Chain: A;	Growth Hormone; Chain: A;	3po2D02

3HOZD 3PO3D 2JA6D 4BBSD 4BXXD 1Y1VD 3HOVD 4A3DD 3H0GD 4A3MD 1Y1WD 5FLMD 2C35A 5IYBD 3HOXD 4A3FD 3HOWD 3AYHA 3I4MD 4A93D 5C44D 2R7ZD 5IYDD 4BY1D 4A3ED 3I4ND 5IP9D 4BY7D 2VUMD 3HOUD 4A3KD 5IYCD 3HOYD 2R93D 2JA5D 2B63D 5C3ED 1Y14A 3PO2D 4A3BD 4A3GD 4A3LD 2JA7D 3FKID 2JA8D 4BBRD 4A3JD 2R92D 3H3VE 5IP7D 4A3CD 4A3ID 5C4XD 1WCMD
chains in the Genus database with same CATH superfamily

3HOZD 4GBZA 3DGCL 4O9HA 3TGXB 1EVSA 1Y1WD 5FLMD 1M4CA 1PW6A 4A3FD 3L5XA 1M47A 1AX8A 3BPLA 3LB6A 1Y6ML 2H24A 1PY2A 2JA7D 3H3VE 3QT2C 4YPGC 4A3DD 4U4TA 2Q7NB 2Z3RA 4DKCA 4TPGA 4J05A 3G6DA 4GC0A 5EQHA 4QIQA 3QB7A 4I77Z 5GXBA 1RHGA 3FKID 3OG6A 1NBPA 3Q1SI 4ZW9A 3HHRA 1PV6A 3HOWD 3I4MD 1BGCA 4A93D 2OQPA 4D2BA 4TPJA 1B5LA 4BY7D 1BUYA 1JLIA 2V8NA 2B63D 4YQXA 3WDOA 4YBQA 1Z92A 2L3YA 1J7VL 3NPZA 3WCYI 2R7ZD 5EQGA 1HIKA 1F45B 4TPHA 3EW3A 4Q65A 2LMSA 3NCCA 2JA5D 1CD9A 2ERJD 1KF9A 2JA8D 1A7MA 2R92D 4BBRD 1ITMA 3D85C 3BPNA 2O27A 3OG4A 3OQ3A 2L3OA 3H0GD 4A3MD 4NN6A 1EKUA 1I1RB 1M4RA 5D58A 1Y6NL 4J4LC 4IKYA 3I4ND 2B8YA 4GS7A 4OAAA 2VUMD 4MHLA 1CNT1 3HOYD 2ILKA 5D22A 3VA2A 4PYPA 3HHCA 1VLKA 1BP3A 3HOVD 5A2NA 3PIWA 4LRLA 4GRWA 3LB6B 3NCEA 2GMFA 4EXNA 3S9DA 4X51A 2Y5YA 1GA3A 1Y6KL 1F6FA 1IARA 3UX9A 4W6VA 1BGEA 5IP7D 1WCMD 1PGRA 4WRLB 1ITLA 4EXPA 4A3ED 1CYLA 5LQBA 4PS4A 4ZS7A 2Z3QA 1ITIA 1LKIA 4JA3A 1AXIA 4GBYA 2B8ZA 1HWHA 4IKWA 3BESL 3AYHA 1BCNA 5D6KA 1V7NV 2CFQA 5IYDD 4BY1D 4ZF7A 1ITFA 3IRHA 4Z5RD 5IYCD 2D9QA 1LK3A 1M4AA 3PIVA 4FA8E 4A3BD 3N06A 1RCBA 5D72A 4U4VA 1V7MV 3UF2A 4IU8A 5E4EA 4CNIC 2C35A 4NKQC 3O7QA 4NEMA 2Q14A 1M49A 1N1FA 3G9VB 1WU3I 4ZWCA 1SCFA 1FYHA 4IKZA 4RS1A 3D87A 1INRA 2B5IA 2LAGA 2PSMA 4A3ID 4DKFA 1RFBA 1IL6A 4JREA 1FG9A 2B91A 5TS9A 4O6KA 2B90A 5IP9D 4D2CA 1HWGA 4D2DA 4IU9A 1P9MB 3UEZE 3D48P 4A3CD 3SE4B 3PO2D 1ETEA 4XNIA 2D48A 5D71A 2XQBA 4DKEA 1ILKA 3QAZA 1IJZA 1PV7A 3DLQI 1HIJA 1IK0A 5L6YC 5C3ED 2O26A 5A2OA 2XUTA 2HYMB 4BBSD 3UF5A 1HUWA 2IL6A 2E9WC 3DI3A 1IRLA 1BGDA 3L5WI 1GNCA 4IKVA 4ZWBA 2CFPA 4NI7A 1HGUA 1HULA 1A22A 1Z7CA 1AU1A 1EXZA 1CSGA 3HMXB 1CN4C 5FUCA 5C4XD 4JR9A 3DI2A 1ALUA 1D9CA 3N0PA 2INTA 3HOXD 2B8XA 4A3KD 4DOHA 4DKDA 4OH3A 4LEPA 1EMRA 1HZIA 4NN7A 3O7PA 3DUHC 3B5KA 2JA6D 4BXXD 4YUEC 3NCFA 4NI9A 3MZGA 1M4BA 1BBNA 5KNHI 2R93D 2B8UA 2CYKA 3QB1A 4YB9D 4NN5A 3PO3D 2KZ1A 1Y1VD 4UVMA 5C7XA 5EQIA 2Q98A 5C44D 3QWRB 1D9GA 1YKBA 3HOUD 1PW4A 1QVNA 4IKXA 3EJJA 4YDYI 1Y14A 4A3GD 4A3LD 4XNJA 1RW5A 3NCBA 5D59A 4APSA 5IYBD 5FHXA 4ZYRA 5D70A 5D28B 1EERA 4NEJA 1M48A 1LQSL 4U4WA 3SE3B 1PVHB 3INKC 3BPOA 4LDSA 5C65A 4A3JD 2O6IA
chains in the Genus database with same CATH topology

3HOZD 3BPNA 2O27A 3DGCL 3OG4A 3DI2A 3UF2A 3OQ3A 4O9HA 1ALUA 1D9CA 2L3OA 3H0GD 3N0PA 1EVSA 2INTA 4NN6A 3TGXB 5E4EA 4CNIC 5FLMD 1M4CA 2C35A 1Y1WD 4NKQC 1EKUA 1PW6A 3HOXD 1I1RB 4NEMA 3L5XA 1M4RA 2B8XA 1M47A 1M49A 2Q14A 1Y6NL 1N1FA 3G9VB 4J4LC 3I4ND 1AX8A 1WU3I 2B8YA 4GS7A 2VUMD 4A3KD 4MHLA 1CNT1 1SCFA 4DOHA 3BPLA 4DKDA 3HOYD 1FYHA 1Y6ML 2H24A 2ILKA 3LB6A 1EMRA 4RS1A 5D22A 3VA2A 1HZIA 3D87A 4NN7A 1INRA 1PY2A 3DUHC 2JA7D 3H3VE 2B5IA 2LAGA 2PSMA 4A3FD 3HHCA 4A3ID 3B5KA 1VLKA 4A3MD 4DKFA 2JA6D 4BXXD 1BP3A 1RFBA 4YUEC 3QT2C 3HOVD 1IL6A 4YPGC 4A3DD 3PIWA 4LRLA 2Q7NB 2Z3RA 1FG9A 3NCFA 2B91A 4GRWA 3LB6B 4DKCA 5TS9A 3NCEA 4NI9A 2GMFA 3G6DA 4O6KA 4EXNA 3MZGA 2B90A 3S9DA 4X51A 5IP9D 1HWGA 1GA3A 1Y6KL 1M4BA 1BBNA 5KNHI 1F6FA 1P9MB 2R93D 1IARA 2B8UA 3QB7A 3UX9A 4I77Z 3UEZE 3D48P 1RHGA 1BGEA 3FKID 2CYKA 3OG6A 3QB1A 5IP7D 1NBPA 4NN5A 4A3CD 3SE4B 1WCMD 3PO2D 3PO3D 2KZ1A 3Q1SI 1ETEA 1Y1VD 2D48A 5D71A 2XQBA 1PGRA 4DKEA 5C7XA 3HHRA 1ILKA 3QAZA 1IJZA 4WRLB 3HOWD 3DLQI 2Q98A 3I4MD 1BGCA 4A93D 2OQPA 1ITLA 3QWRB 1HIJA 4EXPA 5C44D 1IK0A 4A3ED 1CYLA 1D9GA 5LQBA 1B5LA 4BY7D 1BUYA 1YKBA 3HOUD 1JLIA 5L6YC 1QVNA 2B63D 4PS4A 5C3ED 2O26A 3EJJA 4YDYI 1Y14A 4ZS7A 2Z3QA 1ITIA 4YQXA 1LKIA 4A3GD 4A3LD 1AXIA 2HYMB 2B8ZA 1Z92A 4BBSD 3UF5A 2L3YA 1RW5A 1J7VL 1HUWA 1HWHA 3NCBA 2IL6A 2E9WC 3BESL 5IYBD 3DI3A 3NPZA 3AYHA 5FHXA 1BCNA 3WCYI 1IRLA 2R7ZD 1V7NV 5IYDD 4BY1D 1BGDA 5D70A 3L5WI 1HIKA 1GNCA 5D28B 4ZF7A 1ITFA 1F45B 3EW3A 3IRHA 4Z5RD 4NI7A 1HGUA 1EERA 2D9QA 2LMSA 5IYCD 1HULA 1LK3A 1M4AA 4NEJA 1M48A 1A22A 3NCCA 1LQSL 1CD9A 2JA5D 1Z7CA 1AU1A 2ERJD 3SE3B 3PIVA 1EXZA 1KF9A 1PVHB 3INKC 1CSGA 3BPOA 3HMXB 4FA8E 4A3BD 3N06A 2JA8D 2R92D 4BBRD 4A3JD 1A7MA 1ITMA 1CN4C 1RCBA 3D85C 5FUCA 5C4XD 5D72A 1V7MV 2O6IA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3HOZ D;  3PO3 D;  2JA6 D;  4BBS D;  4BXX D;  1Y1V D;  3HOV D;  4A3D D;  3H0G D;  4A3M D;  1Y1W D;  5FLM D;  2C35 A;  5IYB D;  3HOX D;  4A3F D;  3HOW D;  3AYH A;  3I4M D;  4A93 D;  5C44 D;  2R7Z D;  5IYD D;  4BY1 D;  4A3E D;  3I4N D;  5IP9 D;  4BY7 D;  2VUM D;  3HOU D;  4A3K D;  5IYC D;  3HOY D;  2R93 D;  2JA5 D;  2B63 D;  5C3E D;  1Y14 A;  3PO2 D;  4A3B D;  4A3G D;  4A3L D;  2JA7 D;  3FKI D;  2JA8 D;  4BBR D;  4A3J D;  2R92 D;  3H3V E;  5IP7 D;  4A3C D;  4A3I D;  5C4X D;  1WCM D; 
#chains in the Genus database with same CATH topology
 3HOZ D;  4GBZ A;  3DGC L;  4O9H A;  3TGX B;  1EVS A;  1Y1W D;  5FLM D;  1M4C A;  1PW6 A;  4A3F D;  3L5X A;  1M47 A;  1AX8 A;  3BPL A;  3LB6 A;  1Y6M L;  2H24 A;  1PY2 A;  2JA7 D;  3H3V E;  3QT2 C;  4YPG C;  4A3D D;  4U4T A;  2Q7N B;  2Z3R A;  4DKC A;  4TPG A;  4J05 A;  3G6D A;  4GC0 A;  5EQH A;  4QIQ A;  3QB7 A;  4I77 Z;  5GXB A;  1RHG A;  3FKI D;  3OG6 A;  1NBP A;  3Q1S I;  4ZW9 A;  3HHR A;  1PV6 A;  3HOW D;  3I4M D;  1BGC A;  4A93 D;  2OQP A;  4D2B A;  4TPJ A;  1B5L A;  4BY7 D;  1BUY A;  1JLI A;  2V8N A;  2B63 D;  4YQX A;  3WDO A;  4YBQ A;  1Z92 A;  2L3Y A;  1J7V L;  3NPZ A;  3WCY I;  2R7Z D;  5EQG A;  1HIK A;  1F45 B;  4TPH A;  3EW3 A;  4Q65 A;  2LMS A;  3NCC A;  2JA5 D;  1CD9 A;  2ERJ D;  1KF9 A;  2JA8 D;  1A7M A;  2R92 D;  4BBR D;  1ITM A;  3D85 C;  3BPN A;  2O27 A;  3OG4 A;  3OQ3 A;  2L3O A;  3H0G D;  4A3M D;  4NN6 A;  1EKU A;  1I1R B;  1M4R A;  5D58 A;  1Y6N L;  4J4L C;  4IKY A;  3I4N D;  2B8Y A;  4GS7 A;  4OAA A;  2VUM D;  4MHL A;  1CNT 1;  3HOY D;  2ILK A;  5D22 A;  3VA2 A;  4PYP A;  3HHC A;  1VLK A;  1BP3 A;  3HOV D;  5A2N A;  3PIW A;  4LRL A;  4GRW A;  3LB6 B;  3NCE A;  2GMF A;  4EXN A;  3S9D A;  4X51 A;  2Y5Y A;  1GA3 A;  1Y6K L;  1F6F A;  1IAR A;  3UX9 A;  4W6V A;  1BGE A;  5IP7 D;  1WCM D;  1PGR A;  4WRL B;  1ITL A;  4EXP A;  4A3E D;  1CYL A;  5LQB A;  4PS4 A;  4ZS7 A;  2Z3Q A;  1ITI A;  1LKI A;  4JA3 A;  1AXI A;  4GBY A;  2B8Z A;  1HWH A;  4IKW A;  3BES L;  3AYH A;  1BCN A;  5D6K A;  1V7N V;  2CFQ A;  5IYD D;  4BY1 D;  4ZF7 A;  1ITF A;  3IRH A;  4Z5R D;  5IYC D;  2D9Q A;  1LK3 A;  1M4A A;  3PIV A;  4FA8 E;  4A3B D;  3N06 A;  1RCB A;  5D72 A;  4U4V A;  1V7M V;  3UF2 A;  4IU8 A;  5E4E A;  4CNI C;  2C35 A;  4NKQ C;  3O7Q A;  4NEM A;  2Q14 A;  1M49 A;  1N1F A;  3G9V B;  1WU3 I;  4ZWC A;  1SCF A;  1FYH A;  4IKZ A;  4RS1 A;  3D87 A;  1INR A;  2B5I A;  2LAG A;  2PSM A;  4A3I D;  4DKF A;  1RFB A;  1IL6 A;  4JRE A;  1FG9 A;  2B91 A;  5TS9 A;  4O6K A;  2B90 A;  5IP9 D;  4D2C A;  1HWG A;  4D2D A;  4IU9 A;  1P9M B;  3UEZ E;  3D48 P;  4A3C D;  3SE4 B;  3PO2 D;  1ETE A;  4XNI A;  2D48 A;  5D71 A;  2XQB A;  4DKE A;  1ILK A;  3QAZ A;  1IJZ A;  1PV7 A;  3DLQ I;  1HIJ A;  1IK0 A;  5L6Y C;  5C3E D;  2O26 A;  5A2O A;  2XUT A;  2HYM B;  4BBS D;  3UF5 A;  1HUW A;  2IL6 A;  2E9W C;  3DI3 A;  1IRL A;  1BGD A;  3L5W I;  1GNC A;  4IKV A;  4ZWB A;  2CFP A;  4NI7 A;  1HGU A;  1HUL A;  1A22 A;  1Z7C A;  1AU1 A;  1EXZ A;  1CSG A;  3HMX B;  1CN4 C;  5FUC A;  5C4X D;  4JR9 A;  3DI2 A;  1ALU A;  1D9C A;  3N0P A;  2INT A;  3HOX D;  2B8X A;  4A3K D;  4DOH A;  4DKD A;  4OH3 A;  4LEP A;  1EMR A;  1HZI A;  4NN7 A;  3O7P A;  3DUH C;  3B5K A;  2JA6 D;  4BXX D;  4YUE C;  3NCF A;  4NI9 A;  3MZG A;  1M4B A;  1BBN A;  5KNH I;  2R93 D;  2B8U A;  2CYK A;  3QB1 A;  4YB9 D;  4NN5 A;  3PO3 D;  2KZ1 A;  1Y1V D;  4UVM A;  5C7X A;  5EQI A;  2Q98 A;  5C44 D;  3QWR B;  1D9G A;  1YKB A;  3HOU D;  1PW4 A;  1QVN A;  4IKX A;  3EJJ A;  4YDY I;  1Y14 A;  4A3G D;  4A3L D;  4XNJ A;  1RW5 A;  3NCB A;  5D59 A;  4APS A;  5IYB D;  5FHX A;  4ZYR A;  5D70 A;  5D28 B;  1EER A;  4NEJ A;  1M48 A;  1LQS L;  4U4W A;  3SE3 B;  1PVH B;  3INK C;  3BPO A;  4LDS A;  5C65 A;  4A3J D;  2O6I A; 
#chains in the Genus database with same CATH homology
 3HOZ D;  3BPN A;  2O27 A;  3DGC L;  3OG4 A;  3DI2 A;  3UF2 A;  3OQ3 A;  4O9H A;  1ALU A;  1D9C A;  2L3O A;  3H0G D;  3N0P A;  1EVS A;  2INT A;  4NN6 A;  3TGX B;  5E4E A;  4CNI C;  5FLM D;  1M4C A;  2C35 A;  1Y1W D;  4NKQ C;  1EKU A;  1PW6 A;  3HOX D;  1I1R B;  4NEM A;  3L5X A;  1M4R A;  2B8X A;  1M47 A;  1M49 A;  2Q14 A;  1Y6N L;  1N1F A;  3G9V B;  4J4L C;  3I4N D;  1AX8 A;  1WU3 I;  2B8Y A;  4GS7 A;  2VUM D;  4A3K D;  4MHL A;  1CNT 1;  1SCF A;  4DOH A;  3BPL A;  4DKD A;  3HOY D;  1FYH A;  1Y6M L;  2H24 A;  2ILK A;  3LB6 A;  1EMR A;  4RS1 A;  5D22 A;  3VA2 A;  1HZI A;  3D87 A;  4NN7 A;  1INR A;  1PY2 A;  3DUH C;  2JA7 D;  3H3V E;  2B5I A;  2LAG A;  2PSM A;  4A3F D;  3HHC A;  4A3I D;  3B5K A;  1VLK A;  4A3M D;  4DKF A;  2JA6 D;  4BXX D;  1BP3 A;  1RFB A;  4YUE C;  3QT2 C;  3HOV D;  1IL6 A;  4YPG C;  4A3D D;  3PIW A;  4LRL A;  2Q7N B;  2Z3R A;  1FG9 A;  3NCF A;  2B91 A;  4GRW A;  3LB6 B;  4DKC A;  5TS9 A;  3NCE A;  4NI9 A;  2GMF A;  3G6D A;  4O6K A;  4EXN A;  3MZG A;  2B90 A;  3S9D A;  4X51 A;  5IP9 D;  1HWG A;  1GA3 A;  1Y6K L;  1M4B A;  1BBN A;  5KNH I;  1F6F A;  1P9M B;  2R93 D;  1IAR A;  2B8U A;  3QB7 A;  3UX9 A;  4I77 Z;  3UEZ E;  3D48 P;  1RHG A;  1BGE A;  3FKI D;  2CYK A;  3OG6 A;  3QB1 A;  5IP7 D;  1NBP A;  4NN5 A;  4A3C D;  3SE4 B;  1WCM D;  3PO2 D;  3PO3 D;  2KZ1 A;  3Q1S I;  1ETE A;  1Y1V D;  2D48 A;  5D71 A;  2XQB A;  1PGR A;  4DKE A;  5C7X A;  3HHR A;  1ILK A;  3QAZ A;  1IJZ A;  4WRL B;  3HOW D;  3DLQ I;  2Q98 A;  3I4M D;  1BGC A;  4A93 D;  2OQP A;  1ITL A;  3QWR B;  1HIJ A;  4EXP A;  5C44 D;  1IK0 A;  4A3E D;  1CYL A;  1D9G A;  5LQB A;  1B5L A;  4BY7 D;  1BUY A;  1YKB A;  3HOU D;  1JLI A;  5L6Y C;  1QVN A;  2B63 D;  4PS4 A;  5C3E D;  2O26 A;  3EJJ A;  4YDY I;  1Y14 A;  4ZS7 A;  2Z3Q A;  1ITI A;  4YQX A;  1LKI A;  4A3G D;  4A3L D;  1AXI A;  2HYM B;  2B8Z A;  1Z92 A;  4BBS D;  3UF5 A;  2L3Y A;  1RW5 A;  1J7V L;  1HUW A;  1HWH A;  3NCB A;  2IL6 A;  2E9W C;  3BES L;  5IYB D;  3DI3 A;  3NPZ A;  3AYH A;  5FHX A;  1BCN A;  3WCY I;  1IRL A;  2R7Z D;  1V7N V;  5IYD D;  4BY1 D;  1BGD A;  5D70 A;  3L5W I;  1HIK A;  1GNC A;  5D28 B;  4ZF7 A;  1ITF A;  1F45 B;  3EW3 A;  3IRH A;  4Z5R D;  4NI7 A;  1HGU A;  1EER A;  2D9Q A;  2LMS A;  5IYC D;  1HUL A;  1LK3 A;  1M4A A;  4NEJ A;  1M48 A;  1A22 A;  3NCC A;  1LQS L;  1CD9 A;  2JA5 D;  1Z7C A;  1AU1 A;  2ERJ D;  3SE3 B;  3PIV A;  1EXZ A;  1KF9 A;  1PVH B;  3INK C;  1CSG A;  3BPO A;  3HMX B;  4FA8 E;  4A3B D;  3N06 A;  2JA8 D;  2R92 D;  4BBR D;  4A3J D;  1A7M A;  1ITM A;  1CN4 C;  1RCB A;  3D85 C;  5FUC A;  5C4X D;  5D72 A;  1V7M V;  2O6I A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3PO2D

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations