4A3DD

Rna polymerase ii initial transcribing complex with a 6nt dna-rna hybrid
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 52
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a3dD02
5IYBD 2C35A 1Y14A 4BBRD 3HOXD 2B63D 4BY7D 2R7ZD 2R93D 4A3DD 4A3CD 5C3ED 2JA5D 3FKID 3HOWD 3HOVD 2VUMD 3I4ND 1Y1WD 4A3KD 3H3VE 5IYDD 4A3ED 4BY1D 2JA7D 3I4MD 3AYHA 4A3FD 4BBSD 2JA8D 3HOYD 4A3GD 1Y1VD 3HOZD 2R92D 5IYCD 4A3BD 4A93D 4BXXD 5C44D 3H0GD 5IP9D 3PO3D 5FLMD 4A3JD 2JA6D 4A3MD 3PO2D 4A3LD 3HOUD 5IP7D 4A3ID 5C4XD 1WCMD
chains in the Genus database with same CATH superfamily
1N1FA 5D22A 2D48A 1RCBA 1LKIA 5D28B 3UF2A 4TPJA 4TPHA 4D2BA 3NCCA 4LRLA 4A3BD 3QB1A 1EXZA 3H0GD 2CFQA 1FG9A 3NPZA 3O7PA 2B8UA 4OH3A 1LQSL 3OG6A 4ZYRA 1IARA 4MHLA 1Y6NL 1ITFA 4UVMA 4DKFA 2O27A 4BXXD 3L5XA 5D72A 1CN4C 3UX9A 2Y5YA 4IKZA 4ZWCA 1RFBA 1WCMD 1BCNA 4BBRD 3DGCL 4IKVA 2R93D 2O26A 3I4ND 1Y1WD 4Z5RD 2D9QA 4GBYA 1HUWA 1Y6ML 4IKWA 3BPLA 3N0PA 2L3OA 5D58A 2E9WC 2CYKA 3N06A 1WU3I 1AU1A 3WCYI 2OQPA 4YBQA 3HOWD 3Q1SI 2JA7D 4A3FD 2B8YA 4ZF7A 4DKDA 4NEJA 5C44D 5C65A 5EQIA 4A3LD 5D6KA 2KZ1A 3VA2A 1ITIA 3B5KA 1HIJA 2INTA 4GBZA 2B8ZA 1PW4A 3BPOA 1A22A 2V8NA 4A3KD 1ALUA 4PYPA 5IYCD 3PIWA 4A93D 3TGXB 3DI3A 1IL6A 1Z92A 4ZW9A 3PIVA 5A2OA 2C35A 5EQGA 2H24A 4QIQA 4NN6A 1BGEA 1PV7A 5C3ED 3D85C 2IL6A 1V7MV 3H3VE 3UEZE 4BBSD 4GC0A 3HOYD 3DUHC 3SE4B 1P9MB 5GXBA 2GMFA 3QB7A 2B5IA 3IRHA 3HHCA 5EQHA 4A3ED 4ZWBA 1Y6KL 3NCFA 4NKQC 4PS4A 3UF5A 4U4TA 1D9CA 2Q7NB 3MZGA 4A3MD 4LEPA 5D59A 3LB6B 4IKXA 1HZIA 5A2NA 1V7NV 1ITMA 3HOXD 2B63D 1IRLA 4A3DD 4DOHA 4D2DA 1BGDA 1M48A 1Y1VD 2LMSA 2PSMA 1M4RA 4Q65A 4YQXA 3L5WI 4U4VA 2HYMB 4W6VA 4A3JD 3HOUD 1PY2A 2B8XA 1M49A 4XNIA 1Y14A 4GRWA 4A3CD 2JA5D 1A7MA 3SE3B 2Z3QA 4A3GD 4IKYA 4YPGC 2R92D 2Z3RA 1BUYA 3OQ3A 2O6IA 1PV6A 4CNIC 1CYLA 5IYBD 5FUCA 2XUTA 2ERJD 3INKC 4O9HA 1HWHA 3FKID 4GS7A 4U4WA 3O7QA 3HOZD 1B5LA 4O6KA 1M4BA 4NEMA 5IP9D 1CNT1 4I77Z 4JREA 4RS1A 4A3ID 1VLKA 5C4XD 1GA3A 4NN7A 4BY7D 3NCBA 1M47A 1HULA 1RW5A 5IYDD 5D71A 5C7XA 2JA8D 3D87A 4YUEC 3S9DA 1ILKA 1QVNA 1PVHB 1GNCA 4OAAA 4YDYI 1JLIA 1IJZA 4XNJA 4DKCA 1LK3A 4TPGA 1HIKA 3HHRA 3QAZA 3I4MD 1EKUA 1BGCA 1HGUA 3DLQI 1HWGA 3PO3D 3PO2D 3QWRB 4YB9D 1PW6A 4J05A 1AXIA 3EW3A 4EXPA 4BY1D 3D48P 2B90A 2Q14A 5D70A 4APSA 5FLMD 3G6DA 1BBNA 2LAGA 1ITLA 1INRA 1BP3A 5L6YC 3G9VB 2L3YA 5TS9A 2R7ZD 1D9GA 1CD9A 4JR9A 3HOVD 4FA8E 5KNHI 3AYHA 3WDOA 2Q98A 3BPNA 1ETEA 1EVSA 1IK0A 3OG4A 5E4EA 2ILKA 2JA6D 1F45B 5IP7D 1FYHA 1M4AA 3NCEA 1RHGA 1EERA 4ZS7A 2XQBA 4J4LC 4NN5A 5LQBA 4LDSA 1Z7CA 4DKEA 3EJJA 4JA3A 4NI9A 1I1RB 5FHXA 2B91A 3DI2A 3LB6A 4IU8A 3BESL 2CFPA 1J7VL 4X51A 2VUMD 1F6FA 1EMRA 1NBPA 1SCFA 1AX8A 1M4CA 3HMXB 4EXNA 4NI7A 4IU9A 3QT2C 1KF9A 4WRLB 1YKBA 1CSGA 1PGRA 4D2CA
chains in the Genus database with same CATH topology
1HIJA 1Y14A 2INTA 1N1FA 5D22A 2D48A 1AXIA 1RCBA 3EW3A 4GRWA 2B8ZA 4A3CD 1LKIA 1A22A 3BPOA 5D28B 3UF2A 2JA5D 1A7MA 3SE3B 4A3KD 4EXPA 1ALUA 4BY1D 3D48P 2B90A 2Q14A 2Z3QA 3NCCA 4A3GD 4LRLA 4YPGC 2R92D 5IYCD 4A3BD 2Z3RA 3PIWA 4A93D 3QB1A 1BUYA 3OQ3A 1EXZA 3TGXB 3H0GD 2O6IA 5D70A 1FG9A 5FLMD 3NPZA 3G6DA 4CNIC 1BBNA 3DI3A 1CYLA 2LAGA 2B8UA 1IL6A 1ITLA 1Z92A 3PIVA 1LQSL 1INRA 1BP3A 5L6YC 3G9VB 2C35A 2L3YA 5IYBD 2H24A 5FUCA 5TS9A 3OG6A 4NN6A 1D9GA 2ERJD 3INKC 1BGEA 2R7ZD 4O9HA 5C3ED 1CD9A 1HWHA 3FKID 4GS7A 3HOVD 1IARA 3D85C 1Y6NL 4MHLA 2IL6A 4FA8E 1ITFA 1V7MV 4DKFA 3UEZE 5KNHI 3H3VE 4BBSD 3AYHA 3HOYD 2Q98A 3HOZD 3BPNA 3DUHC 3SE4B 1B5LA 1ETEA 2O27A 4O6KA 4BXXD 1EVSA 1IK0A 1M4BA 3OG4A 3L5XA 4NEMA 1P9MB 5D72A 5E4EA 2ILKA 5IP9D 1CNT1 2JA6D 1CN4C 1F45B 3UX9A 4I77Z 5IP7D 4RS1A 4A3ID 1VLKA 1RFBA 2GMFA 5C4XD 1FYHA 1WCMD 1GA3A 1M4AA 3NCEA 1RHGA 3QB7A 1BCNA 2B5IA 4BBRD 4NN7A 3DGCL 4BY7D 2R93D 1EERA 4ZS7A 3IRHA 2XQBA 1M47A 1HULA 2O26A 3HHCA 3NCBA 3I4ND 1Y1WD 4J4LC 1RW5A 4NN5A 4Z5RD 5LQBA 5IYDD 2D9QA 4A3ED 5D71A 1Z7CA 4DKEA 5C7XA 1HUWA 2JA8D 1Y6KL 3EJJA 3NCFA 4NKQC 3D87A 4YUEC 1Y6ML 3S9DA 3BPLA 4PS4A 3N0PA 3UF5A 1ILKA 1D9CA 1QVNA 2L3OA 2Q7NB 3MZGA 4A3MD 2E9WC 4NI9A 1I1RB 2CYKA 1PVHB 3LB6B 1HZIA 3N06A 5FHXA 1GNCA 1WU3I 4YDYI 1JLIA 1V7NV 1ITMA 2B91A 3HOXD 2B63D 1IRLA 3DI2A 3LB6A 1IJZA 1AU1A 3WCYI 4A3DD 3BESL 2OQPA 4DOHA 4DKCA 1J7VL 1LK3A 3Q1SI 4X51A 1F6FA 2VUMD 3HOWD 1EMRA 1NBPA 1BGDA 1HIKA 1M48A 1SCFA 1AX8A 3HHRA 3QAZA 4A3FD 2JA7D 3I4MD 2B8YA 1EKUA 1Y1VD 2LMSA 1BGCA 1M4CA 3HMXB 4EXNA 4ZF7A 1HGUA 2PSMA 4DKDA 4NI7A 1M4RA 3DLQI 4NEJA 1HWGA 4YQXA 5C44D 3L5WI 3PO3D 2HYMB 4A3JD 3PO2D 3QT2C 4A3LD 1KF9A 3HOUD 1PY2A 3QWRB 1YKBA 2KZ1A 1CSGA 4WRLB 1PGRA 3VA2A 1PW6A 1ITIA 2B8XA 3B5KA 1M49A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYB D;  2C35 A;  1Y14 A;  4BBR D;  3HOX D;  2B63 D;  4BY7 D;  2R7Z D;  2R93 D;  4A3D D;  4A3C D;  5C3E D;  2JA5 D;  3FKI D;  3HOW D;  3HOV D;  2VUM D;  3I4N D;  1Y1W D;  4A3K D;  3H3V E;  5IYD D;  4A3E D;  4BY1 D;  2JA7 D;  3I4M D;  3AYH A;  4A3F D;  4BBS D;  2JA8 D;  3HOY D;  4A3G D;  1Y1V D;  3HOZ D;  2R92 D;  5IYC D;  4A3B D;  4A93 D;  4BXX D;  5C44 D;  3H0G D;  5IP9 D;  3PO3 D;  5FLM D;  4A3J D;  2JA6 D;  4A3M D;  3PO2 D;  4A3L D;  3HOU D;  5IP7 D;  4A3I D;  5C4X D;  1WCM D; 
#chains in the Genus database with same CATH topology
 1N1F A;  5D22 A;  2D48 A;  1RCB A;  1LKI A;  5D28 B;  3UF2 A;  4TPJ A;  4TPH A;  4D2B A;  3NCC A;  4LRL A;  4A3B D;  3QB1 A;  1EXZ A;  3H0G D;  2CFQ A;  1FG9 A;  3NPZ A;  3O7P A;  2B8U A;  4OH3 A;  1LQS L;  3OG6 A;  4ZYR A;  1IAR A;  4MHL A;  1Y6N L;  1ITF A;  4UVM A;  4DKF A;  2O27 A;  4BXX D;  3L5X A;  5D72 A;  1CN4 C;  3UX9 A;  2Y5Y A;  4IKZ A;  4ZWC A;  1RFB A;  1WCM D;  1BCN A;  4BBR D;  3DGC L;  4IKV A;  2R93 D;  2O26 A;  3I4N D;  1Y1W D;  4Z5R D;  2D9Q A;  4GBY A;  1HUW A;  1Y6M L;  4IKW A;  3BPL A;  3N0P A;  2L3O A;  5D58 A;  2E9W C;  2CYK A;  3N06 A;  1WU3 I;  1AU1 A;  3WCY I;  2OQP A;  4YBQ A;  3HOW D;  3Q1S I;  2JA7 D;  4A3F D;  2B8Y A;  4ZF7 A;  4DKD A;  4NEJ A;  5C44 D;  5C65 A;  5EQI A;  4A3L D;  5D6K A;  2KZ1 A;  3VA2 A;  1ITI A;  3B5K A;  1HIJ A;  2INT A;  4GBZ A;  2B8Z A;  1PW4 A;  3BPO A;  1A22 A;  2V8N A;  4A3K D;  1ALU A;  4PYP A;  5IYC D;  3PIW A;  4A93 D;  3TGX B;  3DI3 A;  1IL6 A;  1Z92 A;  4ZW9 A;  3PIV A;  5A2O A;  2C35 A;  5EQG A;  2H24 A;  4QIQ A;  4NN6 A;  1BGE A;  1PV7 A;  5C3E D;  3D85 C;  2IL6 A;  1V7M V;  3H3V E;  3UEZ E;  4BBS D;  4GC0 A;  3HOY D;  3DUH C;  3SE4 B;  1P9M B;  5GXB A;  2GMF A;  3QB7 A;  2B5I A;  3IRH A;  3HHC A;  5EQH A;  4A3E D;  4ZWB A;  1Y6K L;  3NCF A;  4NKQ C;  4PS4 A;  3UF5 A;  4U4T A;  1D9C A;  2Q7N B;  3MZG A;  4A3M D;  4LEP A;  5D59 A;  3LB6 B;  4IKX A;  1HZI A;  5A2N A;  1V7N V;  1ITM A;  3HOX D;  2B63 D;  1IRL A;  4A3D D;  4DOH A;  4D2D A;  1BGD A;  1M48 A;  1Y1V D;  2LMS A;  2PSM A;  1M4R A;  4Q65 A;  4YQX A;  3L5W I;  4U4V A;  2HYM B;  4W6V A;  4A3J D;  3HOU D;  1PY2 A;  2B8X A;  1M49 A;  4XNI A;  1Y14 A;  4GRW A;  4A3C D;  2JA5 D;  1A7M A;  3SE3 B;  2Z3Q A;  4A3G D;  4IKY A;  4YPG C;  2R92 D;  2Z3R A;  1BUY A;  3OQ3 A;  2O6I A;  1PV6 A;  4CNI C;  1CYL A;  5IYB D;  5FUC A;  2XUT A;  2ERJ D;  3INK C;  4O9H A;  1HWH A;  3FKI D;  4GS7 A;  4U4W A;  3O7Q A;  3HOZ D;  1B5L A;  4O6K A;  1M4B A;  4NEM A;  5IP9 D;  1CNT 1;  4I77 Z;  4JRE A;  4RS1 A;  4A3I D;  1VLK A;  5C4X D;  1GA3 A;  4NN7 A;  4BY7 D;  3NCB A;  1M47 A;  1HUL A;  1RW5 A;  5IYD D;  5D71 A;  5C7X A;  2JA8 D;  3D87 A;  4YUE C;  3S9D A;  1ILK A;  1QVN A;  1PVH B;  1GNC A;  4OAA A;  4YDY I;  1JLI A;  1IJZ A;  4XNJ A;  4DKC A;  1LK3 A;  4TPG A;  1HIK A;  3HHR A;  3QAZ A;  3I4M D;  1EKU A;  1BGC A;  1HGU A;  3DLQ I;  1HWG A;  3PO3 D;  3PO2 D;  3QWR B;  4YB9 D;  1PW6 A;  4J05 A;  1AXI A;  3EW3 A;  4EXP A;  4BY1 D;  3D48 P;  2B90 A;  2Q14 A;  5D70 A;  4APS A;  5FLM D;  3G6D A;  1BBN A;  2LAG A;  1ITL A;  1INR A;  1BP3 A;  5L6Y C;  3G9V B;  2L3Y A;  5TS9 A;  2R7Z D;  1D9G A;  1CD9 A;  4JR9 A;  3HOV D;  4FA8 E;  5KNH I;  3AYH A;  3WDO A;  2Q98 A;  3BPN A;  1ETE A;  1EVS A;  1IK0 A;  3OG4 A;  5E4E A;  2ILK A;  2JA6 D;  1F45 B;  5IP7 D;  1FYH A;  1M4A A;  3NCE A;  1RHG A;  1EER A;  4ZS7 A;  2XQB A;  4J4L C;  4NN5 A;  5LQB A;  4LDS A;  1Z7C A;  4DKE A;  3EJJ A;  4JA3 A;  4NI9 A;  1I1R B;  5FHX A;  2B91 A;  3DI2 A;  3LB6 A;  4IU8 A;  3BES L;  2CFP A;  1J7V L;  4X51 A;  2VUM D;  1F6F A;  1EMR A;  1NBP A;  1SCF A;  1AX8 A;  1M4C A;  3HMX B;  4EXN A;  4NI7 A;  4IU9 A;  3QT2 C;  1KF9 A;  4WRL B;  1YKB A;  1CSG A;  1PGR A;  4D2C A; 
#chains in the Genus database with same CATH homology
 1HIJ A;  1Y14 A;  2INT A;  1N1F A;  5D22 A;  2D48 A;  1AXI A;  1RCB A;  3EW3 A;  4GRW A;  2B8Z A;  4A3C D;  1LKI A;  1A22 A;  3BPO A;  5D28 B;  3UF2 A;  2JA5 D;  1A7M A;  3SE3 B;  4A3K D;  4EXP A;  1ALU A;  4BY1 D;  3D48 P;  2B90 A;  2Q14 A;  2Z3Q A;  3NCC A;  4A3G D;  4LRL A;  4YPG C;  2R92 D;  5IYC D;  4A3B D;  2Z3R A;  3PIW A;  4A93 D;  3QB1 A;  1BUY A;  3OQ3 A;  1EXZ A;  3TGX B;  3H0G D;  2O6I A;  5D70 A;  1FG9 A;  5FLM D;  3NPZ A;  3G6D A;  4CNI C;  1BBN A;  3DI3 A;  1CYL A;  2LAG A;  2B8U A;  1IL6 A;  1ITL A;  1Z92 A;  3PIV A;  1LQS L;  1INR A;  1BP3 A;  5L6Y C;  3G9V B;  2C35 A;  2L3Y A;  5IYB D;  2H24 A;  5FUC A;  5TS9 A;  3OG6 A;  4NN6 A;  1D9G A;  2ERJ D;  3INK C;  1BGE A;  2R7Z D;  4O9H A;  5C3E D;  1CD9 A;  1HWH A;  3FKI D;  4GS7 A;  3HOV D;  1IAR A;  3D85 C;  1Y6N L;  4MHL A;  2IL6 A;  4FA8 E;  1ITF A;  1V7M V;  4DKF A;  3UEZ E;  5KNH I;  3H3V E;  4BBS D;  3AYH A;  3HOY D;  2Q98 A;  3HOZ D;  3BPN A;  3DUH C;  3SE4 B;  1B5L A;  1ETE A;  2O27 A;  4O6K A;  4BXX D;  1EVS A;  1IK0 A;  1M4B A;  3OG4 A;  3L5X A;  4NEM A;  1P9M B;  5D72 A;  5E4E A;  2ILK A;  5IP9 D;  1CNT 1;  2JA6 D;  1CN4 C;  1F45 B;  3UX9 A;  4I77 Z;  5IP7 D;  4RS1 A;  4A3I D;  1VLK A;  1RFB A;  2GMF A;  5C4X D;  1FYH A;  1WCM D;  1GA3 A;  1M4A A;  3NCE A;  1RHG A;  3QB7 A;  1BCN A;  2B5I A;  4BBR D;  4NN7 A;  3DGC L;  4BY7 D;  2R93 D;  1EER A;  4ZS7 A;  3IRH A;  2XQB A;  1M47 A;  1HUL A;  2O26 A;  3HHC A;  3NCB A;  3I4N D;  1Y1W D;  4J4L C;  1RW5 A;  4NN5 A;  4Z5R D;  5LQB A;  5IYD D;  2D9Q A;  4A3E D;  5D71 A;  1Z7C A;  4DKE A;  5C7X A;  1HUW A;  2JA8 D;  1Y6K L;  3EJJ A;  3NCF A;  4NKQ C;  3D87 A;  4YUE C;  1Y6M L;  3S9D A;  3BPL A;  4PS4 A;  3N0P A;  3UF5 A;  1ILK A;  1D9C A;  1QVN A;  2L3O A;  2Q7N B;  3MZG A;  4A3M D;  2E9W C;  4NI9 A;  1I1R B;  2CYK A;  1PVH B;  3LB6 B;  1HZI A;  3N06 A;  5FHX A;  1GNC A;  1WU3 I;  4YDY I;  1JLI A;  1V7N V;  1ITM A;  2B91 A;  3HOX D;  2B63 D;  1IRL A;  3DI2 A;  3LB6 A;  1IJZ A;  1AU1 A;  3WCY I;  4A3D D;  3BES L;  2OQP A;  4DOH A;  4DKC A;  1J7V L;  1LK3 A;  3Q1S I;  4X51 A;  1F6F A;  2VUM D;  3HOW D;  1EMR A;  1NBP A;  1BGD A;  1HIK A;  1M48 A;  1SCF A;  1AX8 A;  3HHR A;  3QAZ A;  4A3F D;  2JA7 D;  3I4M D;  2B8Y A;  1EKU A;  1Y1V D;  2LMS A;  1BGC A;  1M4C A;  3HMX B;  4EXN A;  4ZF7 A;  1HGU A;  2PSM A;  4DKD A;  4NI7 A;  1M4R A;  3DLQ I;  4NEJ A;  1HWG A;  4YQX A;  5C44 D;  3L5W I;  3PO3 D;  2HYM B;  4A3J D;  3PO2 D;  3QT2 C;  4A3L D;  1KF9 A;  3HOU D;  1PY2 A;  3QWR B;  1YKB A;  2KZ1 A;  1CSG A;  4WRL B;  1PGR A;  3VA2 A;  1PW6 A;  1ITI A;  2B8X A;  3B5K A;  1M49 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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