4A3MD

Rna polymerase ii initial transcribing complex with a 4nt dna-rna hybrid and soaked with ampcpp
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 49
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a3mD02
4A3ID 1Y1WD 4A3BD 4A3ED 2B63D 3AYHA 3H0GD 2R93D 2JA5D 2VUMD 2JA7D 5C44D 4BXXD 4A3CD 4A3LD 3I4MD 5IYCD 5C3ED 4A93D 2JA6D 3HOVD 3PO2D 2R7ZD 3HOUD 4A3KD 5IYBD 3PO3D 3HOYD 5IYDD 1WCMD 5IP9D 3FKID 2R92D 4A3GD 2C35A 4BBSD 5C4XD 1Y1VD 4A3DD 4BBRD 3HOWD 1Y14A 3HOXD 3HOZD 2JA8D 5FLMD 5IP7D 4A3JD 3I4ND 4A3MD 3H3VE 4BY1D 4BY7D 4A3FD
chains in the Genus database with same CATH superfamily
4A3ID 3L5XA 4U4WA 4IKWA 3H0GD 1V7MV 4BXXD 3NCEA 3PO2D 1PY2A 3PIWA 1IL6A 5IYDD 3QWRB 1RCBA 2R92D 1PVHB 1LKIA 1QVNA 1PV6A 2Q98A 3LB6B 5D70A 3L5WI 4NN6A 4YBQA 3DGCL 1BBNA 2B8ZA 1B5LA 2Y5YA 1M47A 4YDYI 4RS1A 3HHRA 1N1FA 4IU8A 3HOWD 1HULA 2O26A 1AXIA 5D28B 1Z92A 3AYHA 1HIKA 2JA5D 1ALUA 4FA8E 1HIJA 3PIVA 4NKQC 4NN7A 1WCMD 1KF9A 5IP9D 3BPLA 1M4RA 3WCYI 3S9DA 5TS9A 4A3DD 5D58A 1GA3A 3I4ND 4U4TA 4A3CD 4ZF7A 3N0PA 2JA6D 1A22A 3NCFA 4LEPA 3Q1SI 4NI9A 3QB1A 3NPZA 5A2NA 4GC0A 2Q7NB 3D85C 4XNJA 2JA8D 1ITMA 4DKCA 4JREA 4EXNA 2B91A 1Y6ML 4NN5A 3BPOA 3BPNA 3I4MD 2OQPA 2D9QA 2LMSA 4D2CA 4IKZA 1RFBA 1CSGA 5D71A 5FLMD 1BUYA 1PW4A 1INRA 3NCBA 4TPHA 5KNHI 2O6IA 1FG9A 5FHXA 2R7ZD 3WDOA 1M4BA 1ETEA 3D48P 1EKUA 1IJZA 3OQ3A 2B90A 4XNIA 4QIQA 4EXPA 1YKBA 1BGDA 2ERJD 3H3VE 3DI2A 3TGXB 2HYMB 4GS7A 1IARA 3OG6A 2VUMD 4ZYRA 2V8NA 1AU1A 5D59A 1LK3A 4ZWBA 3INKC 4ZW9A 3MZGA 2C35A 2B8XA 3HHCA 2XUTA 1Y1VD 1EMRA 2B63D 2KZ1A 1VLKA 1F6FA 2L3YA 5C3ED 1HZIA 4GBYA 2ILKA 5IYBD 3O7QA 1EXZA 2D48A 3BESL 4I77Z 4BBSD 5LQBA 4BBRD 4IKYA 4Z5RD 4D2BA 3UF5A 4A3JD 1ITFA 1ITLA 4A3MD 1PW6A 2XQBA 4OH3A 3EJJA 3G6DA 4X51A 1HWGA 4A93D 4DKFA 1EERA 5GXBA 3HOYD 1SCFA 1HUWA 1BP3A 1PV7A 4MHLA 1F45B 3UEZE 3OG4A 5EQHA 3UX9A 4BY7D 4A3FD 1HWHA 4OAAA 4TPGA 5E4EA 2JA7D 4U4VA 4YB9D 1Y6NL 2Q14A 5C65A 1LQSL 1RHGA 4A3GD 4PYPA 3DLQI 2H24A 5D72A 3IRHA 4IKVA 3HOZD 4GRWA 1BGEA 3EW3A 5EQIA 4Q65A 4A3LD 1NBPA 4J05A 1M48A 4A3KD 2CFPA 3NCCA 4DKDA 1IRLA 3QB7A 1Y14A 3LB6A 1M4CA 4NEMA 1M4AA 1Y1WD 4JR9A 5FUCA 3QAZA 4ZS7A 4O6KA 1D9GA 4YPGC 3HOUD 1J7VL 4ZWCA 4WRLB 3FKID 1PGRA 2GMFA 2Z3QA 5L6YC 1P9MB 2B8UA 2B8YA 4IU9A 1Z7CA 1ITIA 3QT2C 4D2DA 3UF2A 4J4LC 5A2OA 3DUHC 2L3OA 1CN4C 4YQXA 1FYHA 1CYLA 1M49A 4UVMA 4TPJA 1BCNA 1HGUA 4NEJA 1JLIA 4A3ED 4IKXA 3N06A 2PSMA 3SE4B 3HOVD 2E9WC 5EQGA 3VA2A 4GBZA 1WU3I 3HOXD 1GNCA 4APSA 1CNT1 1RW5A 3HMXB 1ILKA 2B5IA 1CD9A 1V7NV 2R93D 5C44D 4LDSA 5D22A 2LAGA 4DOHA 1AX8A 3PO3D 1EVSA 1D9CA 1Y6KL 4O9HA 5C4XD 4NI7A 2IL6A 3DI3A 1IK0A 5C7XA 1BGCA 3SE3B 4DKEA 4A3BD 2INTA 3G9VB 4PS4A 4YUEC 5IYCD 4CNIC 4JA3A 4LRLA 2CYKA 2O27A 1I1RB 3B5KA 2Z3RA 5D6KA 1A7MA 5IP7D 3O7PA 3D87A 2CFQA 4BY1D 4W6VA
chains in the Genus database with same CATH topology
4A3ID 3L5XA 1PW6A 2XQBA 3QT2C 3H0GD 3EJJA 1V7MV 4BXXD 3G6DA 3UF2A 3NCEA 4NN5A 4J4LC 3BPOA 3BPNA 3I4MD 4X51A 1HWGA 4A93D 2OQPA 4DKFA 3PO2D 1EERA 3DUHC 2L3OA 1PY2A 3PIWA 3HOYD 1SCFA 1HUWA 1IL6A 1CN4C 1BP3A 2D9QA 5IYDD 4YQXA 3QWRB 1RCBA 1ITIA 2LMSA 2R92D 1FYHA 1PVHB 1CYLA 1M49A 4MHLA 1LKIA 1F45B 1QVNA 1RFBA 1CSGA 5D71A 3UEZE 1BCNA 5FLMD 3OG4A 1HGUA 3UX9A 2Q98A 3LB6B 1BUYA 5D70A 4A3FD 4BY7D 3L5WI 1INRA 1JLIA 1HWHA 4NEJA 4A3ED 5E4EA 2JA7D 4NN6A 3N06A 3NCBA 5KNHI 2O6IA 2PSMA 1Y6NL 3SE4B 1FG9A 3HOVD 5FHXA 2R7ZD 3DGCL 1M4BA 2E9WC 2Q14A 1ETEA 1LQSL 1BBNA 3D48P 2B8ZA 1B5LA 1RHGA 1EKUA 1M47A 1IJZA 3OQ3A 4YDYI 4A3GD 2B90A 3DLQI 4RS1A 2H24A 5D72A 3VA2A 3HHRA 3IRHA 1N1FA 1WU3I 1Y6ML 3HOWD 3HOZD 3HOXD 1GNCA 1HULA 4EXPA 4GRWA 1CNT1 1BGDA 1RW5A 1YKBA 2ERJD 3HMXB 2O26A 1ILKA 3H3VE 2B5IA 3DI2A 1CD9A 1AXIA 1BGEA 2HYMB 4GS7A 1Z92A 3AYHA 1V7NV 5D28B 1HIKA 1IARA 3EW3A 2R93D 3OG6A 2JA5D 1ALUA 2VUMD 5C44D 4A3LD 1AU1A 1NBPA 5D22A 1LK3A 4FA8E 1HIJA 3INKC 2LAGA 4DOHA 1M48A 1AX8A 3PIVA 4A3KD 3PO3D 4NKQC 1EVSA 1D9CA 4NN7A 1WCMD 1KF9A 5IP9D 1Y6KL 4O9HA 3MZGA 2C35A 3NCCA 4DKDA 2B8XA 3HHCA 3BPLA 1M4RA 1IRLA 5C4XD 3WCYI 1Y1VD 3QB7A 5TS9A 4NI7A 3S9DA 4A3DD 1Y14A 3LB6A 1GA3A 2IL6A 1M4CA 3DI3A 4NEMA 3I4ND 1M4AA 1IK0A 5C7XA 1BGCA 3SE3B 1Y1WD 4DKEA 4A3BD 1EMRA 2INTA 3G9VB 2B63D 2KZ1A 5FUCA 4PS4A 4A3CD 3QAZA 4YUEC 4ZS7A 1VLKA 4O6KA 1F6FA 2L3YA 5IYCD 4ZF7A 4CNIC 1D9GA 1HZIA 3N0PA 4YPGC 1A22A 2ILKA 5C3ED 2JA6D 1J7VL 5IYBD 4LRLA 3HOUD 2CYKA 2O27A 3NCFA 4WRLB 3TGXB 1EXZA 3Q1SI 2D48A 4NI9A 1I1RB 3BESL 3FKID 4I77Z 3QB1A 3B5KA 2Z3RA 3NPZA 4BBSD 1A7MA 5LQBA 1PGRA 2GMFA 2Z3QA 3D85C 2Q7NB 4BBRD 5L6YC 2JA8D 1ITMA 1P9MB 2B8UA 5IP7D 4Z5RD 2B8YA 3UF5A 4DKCA 4EXNA 2B91A 4A3JD 1Z7CA 1ITLA 4A3MD 1ITFA 3D87A 4BY1D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3I D;  1Y1W D;  4A3B D;  4A3E D;  2B63 D;  3AYH A;  3H0G D;  2R93 D;  2JA5 D;  2VUM D;  2JA7 D;  5C44 D;  4BXX D;  4A3C D;  4A3L D;  3I4M D;  5IYC D;  5C3E D;  4A93 D;  2JA6 D;  3HOV D;  3PO2 D;  2R7Z D;  3HOU D;  4A3K D;  5IYB D;  3PO3 D;  3HOY D;  5IYD D;  1WCM D;  5IP9 D;  3FKI D;  2R92 D;  4A3G D;  2C35 A;  4BBS D;  5C4X D;  1Y1V D;  4A3D D;  4BBR D;  3HOW D;  1Y14 A;  3HOX D;  3HOZ D;  2JA8 D;  5FLM D;  5IP7 D;  4A3J D;  3I4N D;  4A3M D;  3H3V E;  4BY1 D;  4BY7 D;  4A3F D; 
#chains in the Genus database with same CATH topology
 4A3I D;  3L5X A;  4U4W A;  4IKW A;  3H0G D;  1V7M V;  4BXX D;  3NCE A;  3PO2 D;  1PY2 A;  3PIW A;  1IL6 A;  5IYD D;  3QWR B;  1RCB A;  2R92 D;  1PVH B;  1LKI A;  1QVN A;  1PV6 A;  2Q98 A;  3LB6 B;  5D70 A;  3L5W I;  4NN6 A;  4YBQ A;  3DGC L;  1BBN A;  2B8Z A;  1B5L A;  2Y5Y A;  1M47 A;  4YDY I;  4RS1 A;  3HHR A;  1N1F A;  4IU8 A;  3HOW D;  1HUL A;  2O26 A;  1AXI A;  5D28 B;  1Z92 A;  3AYH A;  1HIK A;  2JA5 D;  1ALU A;  4FA8 E;  1HIJ A;  3PIV A;  4NKQ C;  4NN7 A;  1WCM D;  1KF9 A;  5IP9 D;  3BPL A;  1M4R A;  3WCY I;  3S9D A;  5TS9 A;  4A3D D;  5D58 A;  1GA3 A;  3I4N D;  4U4T A;  4A3C D;  4ZF7 A;  3N0P A;  2JA6 D;  1A22 A;  3NCF A;  4LEP A;  3Q1S I;  4NI9 A;  3QB1 A;  3NPZ A;  5A2N A;  4GC0 A;  2Q7N B;  3D85 C;  4XNJ A;  2JA8 D;  1ITM A;  4DKC A;  4JRE A;  4EXN A;  2B91 A;  1Y6M L;  4NN5 A;  3BPO A;  3BPN A;  3I4M D;  2OQP A;  2D9Q A;  2LMS A;  4D2C A;  4IKZ A;  1RFB A;  1CSG A;  5D71 A;  5FLM D;  1BUY A;  1PW4 A;  1INR A;  3NCB A;  4TPH A;  5KNH I;  2O6I A;  1FG9 A;  5FHX A;  2R7Z D;  3WDO A;  1M4B A;  1ETE A;  3D48 P;  1EKU A;  1IJZ A;  3OQ3 A;  2B90 A;  4XNI A;  4QIQ A;  4EXP A;  1YKB A;  1BGD A;  2ERJ D;  3H3V E;  3DI2 A;  3TGX B;  2HYM B;  4GS7 A;  1IAR A;  3OG6 A;  2VUM D;  4ZYR A;  2V8N A;  1AU1 A;  5D59 A;  1LK3 A;  4ZWB A;  3INK C;  4ZW9 A;  3MZG A;  2C35 A;  2B8X A;  3HHC A;  2XUT A;  1Y1V D;  1EMR A;  2B63 D;  2KZ1 A;  1VLK A;  1F6F A;  2L3Y A;  5C3E D;  1HZI A;  4GBY A;  2ILK A;  5IYB D;  3O7Q A;  1EXZ A;  2D48 A;  3BES L;  4I77 Z;  4BBS D;  5LQB A;  4BBR D;  4IKY A;  4Z5R D;  4D2B A;  3UF5 A;  4A3J D;  1ITF A;  1ITL A;  4A3M D;  1PW6 A;  2XQB A;  4OH3 A;  3EJJ A;  3G6D A;  4X51 A;  1HWG A;  4A93 D;  4DKF A;  1EER A;  5GXB A;  3HOY D;  1SCF A;  1HUW A;  1BP3 A;  1PV7 A;  4MHL A;  1F45 B;  3UEZ E;  3OG4 A;  5EQH A;  3UX9 A;  4BY7 D;  4A3F D;  1HWH A;  4OAA A;  4TPG A;  5E4E A;  2JA7 D;  4U4V A;  4YB9 D;  1Y6N L;  2Q14 A;  5C65 A;  1LQS L;  1RHG A;  4A3G D;  4PYP A;  3DLQ I;  2H24 A;  5D72 A;  3IRH A;  4IKV A;  3HOZ D;  4GRW A;  1BGE A;  3EW3 A;  5EQI A;  4Q65 A;  4A3L D;  1NBP A;  4J05 A;  1M48 A;  4A3K D;  2CFP A;  3NCC A;  4DKD A;  1IRL A;  3QB7 A;  1Y14 A;  3LB6 A;  1M4C A;  4NEM A;  1M4A A;  1Y1W D;  4JR9 A;  5FUC A;  3QAZ A;  4ZS7 A;  4O6K A;  1D9G A;  4YPG C;  3HOU D;  1J7V L;  4ZWC A;  4WRL B;  3FKI D;  1PGR A;  2GMF A;  2Z3Q A;  5L6Y C;  1P9M B;  2B8U A;  2B8Y A;  4IU9 A;  1Z7C A;  1ITI A;  3QT2 C;  4D2D A;  3UF2 A;  4J4L C;  5A2O A;  3DUH C;  2L3O A;  1CN4 C;  4YQX A;  1FYH A;  1CYL A;  1M49 A;  4UVM A;  4TPJ A;  1BCN A;  1HGU A;  4NEJ A;  1JLI A;  4A3E D;  4IKX A;  3N06 A;  2PSM A;  3SE4 B;  3HOV D;  2E9W C;  5EQG A;  3VA2 A;  4GBZ A;  1WU3 I;  3HOX D;  1GNC A;  4APS A;  1CNT 1;  1RW5 A;  3HMX B;  1ILK A;  2B5I A;  1CD9 A;  1V7N V;  2R93 D;  5C44 D;  4LDS A;  5D22 A;  2LAG A;  4DOH A;  1AX8 A;  3PO3 D;  1EVS A;  1D9C A;  1Y6K L;  4O9H A;  5C4X D;  4NI7 A;  2IL6 A;  3DI3 A;  1IK0 A;  5C7X A;  1BGC A;  3SE3 B;  4DKE A;  4A3B D;  2INT A;  3G9V B;  4PS4 A;  4YUE C;  5IYC D;  4CNI C;  4JA3 A;  4LRL A;  2CYK A;  2O27 A;  1I1R B;  3B5K A;  2Z3R A;  5D6K A;  1A7M A;  5IP7 D;  3O7P A;  3D87 A;  2CFQ A;  4BY1 D;  4W6V A; 
#chains in the Genus database with same CATH homology
 4A3I D;  3L5X A;  1PW6 A;  2XQB A;  3QT2 C;  3H0G D;  3EJJ A;  1V7M V;  4BXX D;  3G6D A;  3UF2 A;  3NCE A;  4NN5 A;  4J4L C;  3BPO A;  3BPN A;  3I4M D;  4X51 A;  1HWG A;  4A93 D;  2OQP A;  4DKF A;  3PO2 D;  1EER A;  3DUH C;  2L3O A;  1PY2 A;  3PIW A;  3HOY D;  1SCF A;  1HUW A;  1IL6 A;  1CN4 C;  1BP3 A;  2D9Q A;  5IYD D;  4YQX A;  3QWR B;  1RCB A;  1ITI A;  2LMS A;  2R92 D;  1FYH A;  1PVH B;  1CYL A;  1M49 A;  4MHL A;  1LKI A;  1F45 B;  1QVN A;  1RFB A;  1CSG A;  5D71 A;  3UEZ E;  1BCN A;  5FLM D;  3OG4 A;  1HGU A;  3UX9 A;  2Q98 A;  3LB6 B;  1BUY A;  5D70 A;  4A3F D;  4BY7 D;  3L5W I;  1INR A;  1JLI A;  1HWH A;  4NEJ A;  4A3E D;  5E4E A;  2JA7 D;  4NN6 A;  3N06 A;  3NCB A;  5KNH I;  2O6I A;  2PSM A;  1Y6N L;  3SE4 B;  1FG9 A;  3HOV D;  5FHX A;  2R7Z D;  3DGC L;  1M4B A;  2E9W C;  2Q14 A;  1ETE A;  1LQS L;  1BBN A;  3D48 P;  2B8Z A;  1B5L A;  1RHG A;  1EKU A;  1M47 A;  1IJZ A;  3OQ3 A;  4YDY I;  4A3G D;  2B90 A;  3DLQ I;  4RS1 A;  2H24 A;  5D72 A;  3VA2 A;  3HHR A;  3IRH A;  1N1F A;  1WU3 I;  1Y6M L;  3HOW D;  3HOZ D;  3HOX D;  1GNC A;  1HUL A;  4EXP A;  4GRW A;  1CNT 1;  1BGD A;  1RW5 A;  1YKB A;  2ERJ D;  3HMX B;  2O26 A;  1ILK A;  3H3V E;  2B5I A;  3DI2 A;  1CD9 A;  1AXI A;  1BGE A;  2HYM B;  4GS7 A;  1Z92 A;  3AYH A;  1V7N V;  5D28 B;  1HIK A;  1IAR A;  3EW3 A;  2R93 D;  3OG6 A;  2JA5 D;  1ALU A;  2VUM D;  5C44 D;  4A3L D;  1AU1 A;  1NBP A;  5D22 A;  1LK3 A;  4FA8 E;  1HIJ A;  3INK C;  2LAG A;  4DOH A;  1M48 A;  1AX8 A;  3PIV A;  4A3K D;  3PO3 D;  4NKQ C;  1EVS A;  1D9C A;  4NN7 A;  1WCM D;  1KF9 A;  5IP9 D;  1Y6K L;  4O9H A;  3MZG A;  2C35 A;  3NCC A;  4DKD A;  2B8X A;  3HHC A;  3BPL A;  1M4R A;  1IRL A;  5C4X D;  3WCY I;  1Y1V D;  3QB7 A;  5TS9 A;  4NI7 A;  3S9D A;  4A3D D;  1Y14 A;  3LB6 A;  1GA3 A;  2IL6 A;  1M4C A;  3DI3 A;  4NEM A;  3I4N D;  1M4A A;  1IK0 A;  5C7X A;  1BGC A;  3SE3 B;  1Y1W D;  4DKE A;  4A3B D;  1EMR A;  2INT A;  3G9V B;  2B63 D;  2KZ1 A;  5FUC A;  4PS4 A;  4A3C D;  3QAZ A;  4YUE C;  4ZS7 A;  1VLK A;  4O6K A;  1F6F A;  2L3Y A;  5IYC D;  4ZF7 A;  4CNI C;  1D9G A;  1HZI A;  3N0P A;  4YPG C;  1A22 A;  2ILK A;  5C3E D;  2JA6 D;  1J7V L;  5IYB D;  4LRL A;  3HOU D;  2CYK A;  2O27 A;  3NCF A;  4WRL B;  3TGX B;  1EXZ A;  3Q1S I;  2D48 A;  4NI9 A;  1I1R B;  3BES L;  3FKI D;  4I77 Z;  3QB1 A;  3B5K A;  2Z3R A;  3NPZ A;  4BBS D;  1A7M A;  5LQB A;  1PGR A;  2GMF A;  2Z3Q A;  3D85 C;  2Q7N B;  4BBR D;  5L6Y C;  2JA8 D;  1ITM A;  1P9M B;  2B8U A;  5IP7 D;  4Z5R D;  2B8Y A;  3UF5 A;  4DKC A;  4EXN A;  2B91 A;  4A3J D;  1Z7C A;  1ITL A;  4A3M D;  1ITF A;  3D87 A;  4BY1 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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