4A93D

Rna polymerase ii elongation complex containing a cpd lesion
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 49
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a93D02
1WCMD 4A3DD 4BXXD 4A3LD 4BY1D 3HOUD 4A93D 5FLMD 3HOWD 3HOZD 4A3CD 3I4MD 5IP7D 5IYDD 4A3FD 4A3MD 3AYHA 1Y1WD 2JA7D 2C35A 5IYCD 5IYBD 3HOYD 3PO2D 5C44D 3H0GD 2JA5D 4A3ED 2JA6D 4A3GD 5C4XD 2R7ZD 4BY7D 1Y14A 3HOXD 4A3ID 3H3VE 1Y1VD 2B63D 2JA8D 4A3JD 2R92D 4A3KD 5IP9D 3HOVD 3FKID 3I4ND 4BBSD 3PO3D 4BBRD 5C3ED 2R93D 2VUMD 4A3BD
chains in the Genus database with same CATH superfamily
2ERJD 4BXXD 4FA8E 2V8NA 4D2CA 1D9GA 4GC0A 4J05A 1ITIA 4X51A 1M48A 1PGRA 2Z3QA 2Q7NB 4DKFA 2D9QA 3IRHA 3HOVD 4TPJA 3HOYD 1ITMA 3INKC 4UVMA 4U4TA 5IYBD 3PO2D 1A22A 1B5LA 2Z3RA 3N06A 4GBYA 3UEZE 2PSMA 4A3ED 3D85C 2B63D 3O7QA 3WCYI 4PYPA 3DI3A 1HULA 1ILKA 5FLMD 1BUYA 4JREA 3PIWA 1RCBA 2B5IA 3NCCA 4O6KA 1EERA 2XQBA 4CNIC 4GRWA 1N1FA 4NI9A 3G6DA 4BBRD 3OG6A 3MZGA 2R93D 4D2BA 2INTA 1PV6A 2JA7D 3UX9A 4YB9D 1EVSA 4LDSA 2D48A 5E4EA 2B8XA 4LEPA 1ITFA 2Q98A 4ZWBA 1IJZA 4A3LD 3HOZD 4DKEA 1V7MV 1IL6A 1P9MB 4YDYI 1V7NV 4ZYRA 5EQGA 3TGXB 3WDOA 1BBNA 3PIVA 3DI2A 4DOHA 2L3YA 4IKXA 1J7VL 5C7XA 3D87A 1IARA 2XUTA 4BBSD 4ZF7A 2GMFA 2VUMD 1HWHA 1HWGA 4GBZA 1M4CA 1M4RA 1BCNA 1SCFA 5D58A 4OAAA 2H24A 2E9WC 4QIQA 4Q65A 1BGCA 1EMRA 1M47A 2Q14A 2C35A 1HUWA 1RFBA 3NCBA 5FHXA 5TS9A 4OH3A 4DKDA 2B90A 2B8YA 4U4VA 1BP3A 4LRLA 1INRA 5D72A 4BY1D 3HOUD 4PS4A 4TPHA 3B5KA 2CFQA 3SE4B 4XNIA 1F45B 1F6FA 5A2OA 1FYHA 4NN5A 2CYKA 5EQIA 1AU1A 2CFPA 3HOXD 1Y6ML 2JA8D 1HGUA 1IK0A 5A2NA 4D2DA 3QT2C 1D9CA 1PW6A 1RW5A 1WCMD 3QB1A 5L6YC 1VLKA 3O7PA 3BPLA 4WRLB 4NEJA 4W6VA 1Y14A 3NCFA 4ZWCA 3EW3A 5D71A 3EJJA 5D70A 1PY2A 3NPZA 4EXPA 1AXIA 5IP7D 1PVHB 4A3MD 4DKCA 1Y1WD 2O26A 2ILKA 2IL6A 1QVNA 4EXNA 3NCEA 5LQBA 3BPNA 1ALUA 2O6IA 4A3JD 1CD9A 4A3KD 1AX8A 5D6KA 1YKBA 3D48P 3HOWD 2B8UA 5C65A 1HZIA 3S9DA 5IYDD 3G9VB 1GA3A 4IKZA 1LK3A 1WU3I 3HHRA 3H3VE 1EKUA 1RHGA 4I77Z 4XNJA 1CSGA 4NN6A 3PO3D 5D28B 1BGEA 1EXZA 2HYMB 5C3ED 4A3BD 2B8ZA 3DGCL 3DLQI 4A3DD 1BGDA 1GNCA 1M49A 1IRLA 3QWRB 4A3CD 4A3FD 1A7MA 4YQXA 2O27A 3H0GD 4NKQC 4IKVA 4IU8A 3OQ3A 4YBQA 1LQSL 2L3OA 4GS7A 3LB6A 1I1RB 3I4MD 4APSA 3Q1SI 1PV7A 1HIJA 3N0PA 4JA3A 3L5XA 3AYHA 1FG9A 4U4WA 2LAGA 3HHCA 5EQHA 1Y1VD 2R92D 3L5WI 2LMSA 5D59A 2Y5YA 1NBPA 3QAZA 5D22A 5FUCA 4JR9A 4ZS7A 4NEMA 5IYCD 3QB7A 4TPGA 4YUEC 4A3GD 1HIKA 4BY7D 3LB6B 3BESL 4A3ID 3OG4A 1PW4A 1ITLA 1CN4C 1Y6KL 1Y6NL 5KNHI 1Z92A 4ZW9A 4YPGC 4J4LC 1M4AA 5C44D 3UF5A 4IKWA 1M4BA 2JA6D 2R7ZD 2KZ1A 1ETEA 4NN7A 5GXBA 3BPOA 1CNT1 1Z7CA 5IP9D 1LKIA 4IKYA 2OQPA 4Z5RD 3VA2A 4A93D 3HMXB 4O9HA 2JA5D 3SE3B 1JLIA 5C4XD 4RS1A 4IU9A 4NI7A 3UF2A 3FKID 3I4ND 2B91A 3DUHC 1CYLA 1KF9A 4MHLA
chains in the Genus database with same CATH topology
1D9CA 1PW6A 1RW5A 1IJZA 1WCMD 2ERJD 1VLKA 3Q1SI 3QB1A 5L6YC 4NI9A 4BXXD 4A3LD 1HIJA 3HOZD 4DKEA 1V7MV 4FA8E 3I4MD 3N0PA 1IL6A 3L5XA 1P9MB 3AYHA 4YDYI 1V7NV 1D9GA 1FG9A 3TGXB 1ITIA 1BBNA 1M48A 2LAGA 3BPLA 3PIVA 3DI2A 1PGRA 1Y14A 3NCFA 4NEJA 3HHCA 4WRLB 3EW3A 2Z3QA 4DOHA 2Q7NB 5D71A 1Y1VD 2L3YA 3EJJA 4DKFA 2D9QA 3IRHA 1J7VL 5C7XA 2R92D 3D87A 1IARA 3L5WI 2LMSA 3HOVD 4BBSD 5D70A 2GMFA 1PY2A 4ZF7A 1NBPA 1ITMA 3QAZA 3NPZA 2VUMD 3INKC 5D22A 4EXPA 3HOYD 1HWHA 1AXIA 1HWGA 5IP7D 1M4CA 1PVHB 4A3MD 1M4RA 5FUCA 1SCFA 4DKCA 1Y1WD 2O26A 4ZS7A 1BCNA 4NEMA 5IYCD 5IYBD 3PO2D 1A22A 1B5LA 2Z3RA 3N06A 3QB7A 2ILKA 3UEZE 4YUEC 2IL6A 1QVNA 2PSMA 4A3ED 4A3GD 3D85C 1HIKA 4BY7D 3LB6B 3BESL 4EXNA 4A3ID 3NCEA 5LQBA 3OG4A 1CYLA 3BPNA 4X51A 2B63D 2H24A 1ALUA 2O6IA 2E9WC 5D28B 4A3JD 1ITLA 1CD9A 4A3KD 1AX8A 3WCYI 1CN4C 1BGCA 1EMRA 3DI3A 1Y6KL 1HULA 1Y6NL 1M47A 1ILKA 1YKBA 2Q14A 3D48P 5FLMD 5KNHI 3HOWD 2B8UA 1BUYA 1HZIA 3S9DA 5IYDD 1Z92A 1RCBA 2B5IA 3G9VB 3NCCA 3PIWA 4YPGC 2C35A 1HUWA 1GA3A 1RFBA 4J4LC 1M4AA 3UF5A 5C44D 3NCBA 1LK3A 1WU3I 1EERA 4O6KA 5FHXA 1M4BA 2XQBA 4CNIC 2JA6D 4GRWA 3HHRA 5TS9A 2R7ZD 2KZ1A 1ETEA 4NN7A 3H3VE 4DKDA 2B90A 1EKUA 1RHGA 1N1FA 2B8YA 4I77Z 3BPOA 1BP3A 1CNT1 1CSGA 4NN6A 1Z7CA 5IP9D 3PO3D 1LKIA 4LRLA 1BGEA 1EXZA 1INRA 2HYMB 2OQPA 2B8ZA 3G6DA 3MZGA 3OG6A 4BBRD 5C3ED 3DGCL 4A3BD 2R93D 3DLQI 4Z5RD 4A3DD 1BGDA 5D72A 3VA2A 1M49A 4BY1D 1IRLA 1GNCA 3QWRB 3HOUD 4A93D 4PS4A 4A3CD 3HMXB 3B5KA 4A3FD 2INTA 4O9HA 4YQXA 3SE4B 1A7MA 2JA7D 3UX9A 2O27A 1F45B 1EVSA 1F6FA 3H0GD 1FYHA 4NKQC 2JA5D 4NN5A 2CYKA 3SE3B 1AU1A 1JLIA 2D48A 4RS1A 5E4EA 5C4XD 2B8XA 3HOXD 3OQ3A 4NI7A 1Y6ML 1LQSL 3UF2A 2L3OA 2JA8D 1ITFA 4GS7A 3LB6A 1HGUA 1I1RB 3FKID 3I4ND 2B91A 1IK0A 3DUHC 2Q98A 3QT2C 1KF9A 4MHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WCM D;  4A3D D;  4BXX D;  4A3L D;  4BY1 D;  3HOU D;  4A93 D;  5FLM D;  3HOW D;  3HOZ D;  4A3C D;  3I4M D;  5IP7 D;  5IYD D;  4A3F D;  4A3M D;  3AYH A;  1Y1W D;  2JA7 D;  2C35 A;  5IYC D;  5IYB D;  3HOY D;  3PO2 D;  5C44 D;  3H0G D;  2JA5 D;  4A3E D;  2JA6 D;  4A3G D;  5C4X D;  2R7Z D;  4BY7 D;  1Y14 A;  3HOX D;  4A3I D;  3H3V E;  1Y1V D;  2B63 D;  2JA8 D;  4A3J D;  2R92 D;  4A3K D;  5IP9 D;  3HOV D;  3FKI D;  3I4N D;  4BBS D;  3PO3 D;  4BBR D;  5C3E D;  2R93 D;  2VUM D;  4A3B D; 
#chains in the Genus database with same CATH topology
 2ERJ D;  4BXX D;  4FA8 E;  2V8N A;  4D2C A;  1D9G A;  4GC0 A;  4J05 A;  1ITI A;  4X51 A;  1M48 A;  1PGR A;  2Z3Q A;  2Q7N B;  4DKF A;  2D9Q A;  3IRH A;  3HOV D;  4TPJ A;  3HOY D;  1ITM A;  3INK C;  4UVM A;  4U4T A;  5IYB D;  3PO2 D;  1A22 A;  1B5L A;  2Z3R A;  3N06 A;  4GBY A;  3UEZ E;  2PSM A;  4A3E D;  3D85 C;  2B63 D;  3O7Q A;  3WCY I;  4PYP A;  3DI3 A;  1HUL A;  1ILK A;  5FLM D;  1BUY A;  4JRE A;  3PIW A;  1RCB A;  2B5I A;  3NCC A;  4O6K A;  1EER A;  2XQB A;  4CNI C;  4GRW A;  1N1F A;  4NI9 A;  3G6D A;  4BBR D;  3OG6 A;  3MZG A;  2R93 D;  4D2B A;  2INT A;  1PV6 A;  2JA7 D;  3UX9 A;  4YB9 D;  1EVS A;  4LDS A;  2D48 A;  5E4E A;  2B8X A;  4LEP A;  1ITF A;  2Q98 A;  4ZWB A;  1IJZ A;  4A3L D;  3HOZ D;  4DKE A;  1V7M V;  1IL6 A;  1P9M B;  4YDY I;  1V7N V;  4ZYR A;  5EQG A;  3TGX B;  3WDO A;  1BBN A;  3PIV A;  3DI2 A;  4DOH A;  2L3Y A;  4IKX A;  1J7V L;  5C7X A;  3D87 A;  1IAR A;  2XUT A;  4BBS D;  4ZF7 A;  2GMF A;  2VUM D;  1HWH A;  1HWG A;  4GBZ A;  1M4C A;  1M4R A;  1BCN A;  1SCF A;  5D58 A;  4OAA A;  2H24 A;  2E9W C;  4QIQ A;  4Q65 A;  1BGC A;  1EMR A;  1M47 A;  2Q14 A;  2C35 A;  1HUW A;  1RFB A;  3NCB A;  5FHX A;  5TS9 A;  4OH3 A;  4DKD A;  2B90 A;  2B8Y A;  4U4V A;  1BP3 A;  4LRL A;  1INR A;  5D72 A;  4BY1 D;  3HOU D;  4PS4 A;  4TPH A;  3B5K A;  2CFQ A;  3SE4 B;  4XNI A;  1F45 B;  1F6F A;  5A2O A;  1FYH A;  4NN5 A;  2CYK A;  5EQI A;  1AU1 A;  2CFP A;  3HOX D;  1Y6M L;  2JA8 D;  1HGU A;  1IK0 A;  5A2N A;  4D2D A;  3QT2 C;  1D9C A;  1PW6 A;  1RW5 A;  1WCM D;  3QB1 A;  5L6Y C;  1VLK A;  3O7P A;  3BPL A;  4WRL B;  4NEJ A;  4W6V A;  1Y14 A;  3NCF A;  4ZWC A;  3EW3 A;  5D71 A;  3EJJ A;  5D70 A;  1PY2 A;  3NPZ A;  4EXP A;  1AXI A;  5IP7 D;  1PVH B;  4A3M D;  4DKC A;  1Y1W D;  2O26 A;  2ILK A;  2IL6 A;  1QVN A;  4EXN A;  3NCE A;  5LQB A;  3BPN A;  1ALU A;  2O6I A;  4A3J D;  1CD9 A;  4A3K D;  1AX8 A;  5D6K A;  1YKB A;  3D48 P;  3HOW D;  2B8U A;  5C65 A;  1HZI A;  3S9D A;  5IYD D;  3G9V B;  1GA3 A;  4IKZ A;  1LK3 A;  1WU3 I;  3HHR A;  3H3V E;  1EKU A;  1RHG A;  4I77 Z;  4XNJ A;  1CSG A;  4NN6 A;  3PO3 D;  5D28 B;  1BGE A;  1EXZ A;  2HYM B;  5C3E D;  4A3B D;  2B8Z A;  3DGC L;  3DLQ I;  4A3D D;  1BGD A;  1GNC A;  1M49 A;  1IRL A;  3QWR B;  4A3C D;  4A3F D;  1A7M A;  4YQX A;  2O27 A;  3H0G D;  4NKQ C;  4IKV A;  4IU8 A;  3OQ3 A;  4YBQ A;  1LQS L;  2L3O A;  4GS7 A;  3LB6 A;  1I1R B;  3I4M D;  4APS A;  3Q1S I;  1PV7 A;  1HIJ A;  3N0P A;  4JA3 A;  3L5X A;  3AYH A;  1FG9 A;  4U4W A;  2LAG A;  3HHC A;  5EQH A;  1Y1V D;  2R92 D;  3L5W I;  2LMS A;  5D59 A;  2Y5Y A;  1NBP A;  3QAZ A;  5D22 A;  5FUC A;  4JR9 A;  4ZS7 A;  4NEM A;  5IYC D;  3QB7 A;  4TPG A;  4YUE C;  4A3G D;  1HIK A;  4BY7 D;  3LB6 B;  3BES L;  4A3I D;  3OG4 A;  1PW4 A;  1ITL A;  1CN4 C;  1Y6K L;  1Y6N L;  5KNH I;  1Z92 A;  4ZW9 A;  4YPG C;  4J4L C;  1M4A A;  5C44 D;  3UF5 A;  4IKW A;  1M4B A;  2JA6 D;  2R7Z D;  2KZ1 A;  1ETE A;  4NN7 A;  5GXB A;  3BPO A;  1CNT 1;  1Z7C A;  5IP9 D;  1LKI A;  4IKY A;  2OQP A;  4Z5R D;  3VA2 A;  4A93 D;  3HMX B;  4O9H A;  2JA5 D;  3SE3 B;  1JLI A;  5C4X D;  4RS1 A;  4IU9 A;  4NI7 A;  3UF2 A;  3FKI D;  3I4N D;  2B91 A;  3DUH C;  1CYL A;  1KF9 A;  4MHL A; 
#chains in the Genus database with same CATH homology
 1D9C A;  1PW6 A;  1RW5 A;  1IJZ A;  1WCM D;  2ERJ D;  1VLK A;  3Q1S I;  3QB1 A;  5L6Y C;  4NI9 A;  4BXX D;  4A3L D;  1HIJ A;  3HOZ D;  4DKE A;  1V7M V;  4FA8 E;  3I4M D;  3N0P A;  1IL6 A;  3L5X A;  1P9M B;  3AYH A;  4YDY I;  1V7N V;  1D9G A;  1FG9 A;  3TGX B;  1ITI A;  1BBN A;  1M48 A;  2LAG A;  3BPL A;  3PIV A;  3DI2 A;  1PGR A;  1Y14 A;  3NCF A;  4NEJ A;  3HHC A;  4WRL B;  3EW3 A;  2Z3Q A;  4DOH A;  2Q7N B;  5D71 A;  1Y1V D;  2L3Y A;  3EJJ A;  4DKF A;  2D9Q A;  3IRH A;  1J7V L;  5C7X A;  2R92 D;  3D87 A;  1IAR A;  3L5W I;  2LMS A;  3HOV D;  4BBS D;  5D70 A;  2GMF A;  1PY2 A;  4ZF7 A;  1NBP A;  1ITM A;  3QAZ A;  3NPZ A;  2VUM D;  3INK C;  5D22 A;  4EXP A;  3HOY D;  1HWH A;  1AXI A;  1HWG A;  5IP7 D;  1M4C A;  1PVH B;  4A3M D;  1M4R A;  5FUC A;  1SCF A;  4DKC A;  1Y1W D;  2O26 A;  4ZS7 A;  1BCN A;  4NEM A;  5IYC D;  5IYB D;  3PO2 D;  1A22 A;  1B5L A;  2Z3R A;  3N06 A;  3QB7 A;  2ILK A;  3UEZ E;  4YUE C;  2IL6 A;  1QVN A;  2PSM A;  4A3E D;  4A3G D;  3D85 C;  1HIK A;  4BY7 D;  3LB6 B;  3BES L;  4EXN A;  4A3I D;  3NCE A;  5LQB A;  3OG4 A;  1CYL A;  3BPN A;  4X51 A;  2B63 D;  2H24 A;  1ALU A;  2O6I A;  2E9W C;  5D28 B;  4A3J D;  1ITL A;  1CD9 A;  4A3K D;  1AX8 A;  3WCY I;  1CN4 C;  1BGC A;  1EMR A;  3DI3 A;  1Y6K L;  1HUL A;  1Y6N L;  1M47 A;  1ILK A;  1YKB A;  2Q14 A;  3D48 P;  5FLM D;  5KNH I;  3HOW D;  2B8U A;  1BUY A;  1HZI A;  3S9D A;  5IYD D;  1Z92 A;  1RCB A;  2B5I A;  3G9V B;  3NCC A;  3PIW A;  4YPG C;  2C35 A;  1HUW A;  1GA3 A;  1RFB A;  4J4L C;  1M4A A;  3UF5 A;  5C44 D;  3NCB A;  1LK3 A;  1WU3 I;  1EER A;  4O6K A;  5FHX A;  1M4B A;  2XQB A;  4CNI C;  2JA6 D;  4GRW A;  3HHR A;  5TS9 A;  2R7Z D;  2KZ1 A;  1ETE A;  4NN7 A;  3H3V E;  4DKD A;  2B90 A;  1EKU A;  1RHG A;  1N1F A;  2B8Y A;  4I77 Z;  3BPO A;  1BP3 A;  1CNT 1;  1CSG A;  4NN6 A;  1Z7C A;  5IP9 D;  3PO3 D;  1LKI A;  4LRL A;  1BGE A;  1EXZ A;  1INR A;  2HYM B;  2OQP A;  2B8Z A;  3G6D A;  3MZG A;  3OG6 A;  4BBR D;  5C3E D;  3DGC L;  4A3B D;  2R93 D;  3DLQ I;  4Z5R D;  4A3D D;  1BGD A;  5D72 A;  3VA2 A;  1M49 A;  4BY1 D;  1IRL A;  1GNC A;  3QWR B;  3HOU D;  4A93 D;  4PS4 A;  4A3C D;  3HMX B;  3B5K A;  4A3F D;  2INT A;  4O9H A;  4YQX A;  3SE4 B;  1A7M A;  2JA7 D;  3UX9 A;  2O27 A;  1F45 B;  1EVS A;  1F6F A;  3H0G D;  1FYH A;  4NKQ C;  2JA5 D;  4NN5 A;  2CYK A;  3SE3 B;  1AU1 A;  1JLI A;  2D48 A;  4RS1 A;  5E4E A;  5C4X D;  2B8X A;  3HOX D;  3OQ3 A;  4NI7 A;  1Y6M L;  1LQS L;  3UF2 A;  2L3O A;  2JA8 D;  1ITF A;  4GS7 A;  3LB6 A;  1HGU A;  1I1R B;  3FKI D;  3I4N D;  2B91 A;  1IK0 A;  3DUH C;  2Q98 A;  3QT2 C;  1KF9 A;  4MHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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