4APSA

Crystal structure of a pot family peptide transporter in an inward open conformation.
Total Genus 143
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
461
structure length
446
Chain Sequence
QPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMIVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLAPKAFNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transport protein
source organism Streptococcus thermophilus
publication title Alternating Access Mechanism in the Pot Family of Oligopeptide Transporters.
pubmed doi rcsb
molecule keywords DI-OR TRIPEPTIDE H+ SYMPORTER
total genus 143
structure length 446
sequence length 461
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00854 PTR2 POT family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4apsA00
4W6VA 4IKXA 4TPJA 4GBYA 4TPHA 4JA3A 4IKYA 5A2OA 5GXBA 4IKVA 4UVMA 3O7PA 1PW4A 4LEPA 4OH3A 5EQIA 4IU9A 4ZYRA 4JREA 4QIQA 5A2NA 4LDSA 4XNIA 2Y5YA 4JR9A 3WDOA 5EQGA 4PYPA 5D59A 4APSA 2CFQA 4IU8A 4J05A 4Q65A 4OAAA 4GBZA 4GC0A 5EQHA 5D58A 4D2DA 4IKWA 4ZWBA 1PV6A 2XUTA 4ZW9A 4XNJA 5C65A 4IKZA 4ZWCA 4U4WA 4TPGA 4U4VA 4D2CA 2CFPA 4YB9D 1PV7A 3O7QA 5D6KA 4D2BA 4U4TA 4YBQA 2V8NA
chains in the Genus database with same CATH superfamily
4X51A 1RCBA 4PS4A 3WCYI 5C3ED 3PIVA 4NEJA 4XNIA 1YKBA 2B8XA 4BXXD 3HOYD 3PO3D 1EVSA 4XNJA 1D9CA 2Z3RA 3HOVD 3D85C 3DI2A 4YPGC 4DKEA 1BCNA 3BPLA 2JA8D 5C7XA 3DLQI 3G6DA 1F45B 4A3JD 4GRWA 1GNCA 4NI7A 2R92D 1ALUA 5IYBD 4Z5RD 1Y6KL 3INKC 1RFBA 1HWGA 5D72A 4W6VA 5D22A 1EXZA 1ITFA 4ZYRA 4BY1D 4QIQA 3HOXD 4A3BD 5D28B 3Q1SI 4LDSA 3IRHA 5EQGA 4NI9A 1HGUA 4IU8A 4D2DA 2B8UA 3HHCA 2B8ZA 4A3ED 5D6KA 2INTA 1INRA 1BP3A 4IKYA 1AXIA 1EKUA 4A3DD 5KNHI 4FA8E 5A2NA 1PW6A 1M4BA 4NKQC 1Y14A 1VLKA 4Q65A 1Y6NL 2R93D 4IKWA 5L6YC 2JA5D 3HMXB 1N1FA 3SE4B 4TPHA 1M4CA 1HZIA 2B90A 3UEZE 1RW5A 1WU3I 3QB1A 2ILKA 2OQPA 3N06A 1ILKA 1J7VL 4A3GD 4A93D 1JLIA 4U4WA 4D2CA 4O9HA 2VUMD 5E4EA 3SE3B 4CNIC 2KZ1A 2D48A 1IK0A 2B63D 4OH3A 3S9DA 5FLMD 1CNT1 1ITLA 3WDOA 5IYDD 1CYLA 4A3CD 5D59A 3G9VB 2Q7NB 4BBRD 5C65A 2XUTA 1LKIA 2B8YA 4U4TA 1M49A 1SCFA 3D48P 2L3YA 1M48A 1PGRA 5LQBA 3O7PA 3NCCA 1Z92A 5C4XD 3VA2A 4JR9A 3HHRA 4PYPA 1P9MB 4GC0A 1V7MV 3BPOA 4A3ID 1IRLA 5IYCD 4D2BA 3H3VE 2Q14A 3UF5A 1BGCA 1IJZA 3FKID 4YDYI 1PW4A 3OQ3A 1HULA 1HUWA 3QWRB 2HYMB 1A22A 2Y5YA 3NPZA 2B5IA 5D58A 4NEMA 4I77Z 4ZW9A 4A3FD 4TPGA 4YB9D 4TPJA 1Y6ML 1HIKA 3HOZD 3DI3A 1I1RB 1ITMA 3N0PA 2E9WC 1QVNA 3L5XA 5EQHA 1KF9A 1PV6A 1PY2A 3D87A 2O6IA 1LK3A 1M4AA 4YBQA 3OG4A 1LQSL 3LB6B 3OG6A 4WRLB 4JA3A 3EJJA 3EW3A 1IARA 2B91A 4JREA 3UX9A 2JA7D 2XQBA 2Q98A 5D71A 2O27A 4LRLA 3I4MD 4A3LD 4DKDA 2V8NA 1CSGA 3DGCL 4IKVA 4ZF7A 5EQIA 2ERJD 1BGDA 1Y1WD 1Y1VD 1NBPA 1M4RA 5A2OA 2Z3QA 5GXBA 1CN4C 1ITIA 3NCEA 1BUYA 1EMRA 4J05A 2LAGA 3H0GD 4DOHA 1FYHA 3B5KA 1AU1A 2JA6D 3PO2D 3QAZA 5IP9D 3NCFA 2IL6A 5TS9A 4YUEC 1F6FA 4YQXA 2C35A 2R7ZD 4NN6A 1ETEA 4ZWCA 2CFPA 1V7NV 3I4ND 4IKXA 2O26A 4GS7A 5D70A 2H24A 3QB7A 5IP7D 2LMSA 1AX8A 3TGXB 3AYHA 3MZGA 5FUCA 4ZWBA 4EXNA 1M47A 1FG9A 4U4VA 1HIJA 3O7QA 4J4LC 1IL6A 2CYKA 4UVMA 3BESL 2L3OA 4LEPA 1PVHB 4NN7A 4MHLA 4DKFA 4ZS7A 1GA3A 1BGEA 2PSMA 3BPNA 1BBNA 4APSA 3L5WI 4OAAA 5FHXA 4IKZA 3UF2A 3HOUD 3PIWA 4GBYA 4IU9A 3NCBA 4BBSD 4O6KA 3LB6A 5C44D 2D9QA 3QT2C 4A3KD 4EXPA 2CFQA 4A3MD 1HWHA 4GBZA 3DUHC 4RS1A 1RHGA 4DKCA 1D9GA 4NN5A 1WCMD 1CD9A 1Z7CA 2GMFA 1PV7A 3HOWD 1A7MA 1EERA 1B5LA 4BY7D
chains in the Genus database with same CATH topology
4W6VA 4IKXA 4TPJA 4GBYA 4TPHA 4JA3A 4IKYA 5A2OA 5GXBA 4IKVA 4UVMA 3O7PA 1PW4A 4LEPA 4OH3A 5EQIA 4IU9A 4ZYRA 4JREA 4QIQA 5A2NA 4LDSA 4XNIA 2Y5YA 4JR9A 3WDOA 5EQGA 4PYPA 5D59A 4APSA 2CFQA 4IU8A 4J05A 4Q65A 4OAAA 4GBZA 4GC0A 5EQHA 5D58A 4D2DA 4IKWA 4ZWBA 1PV6A 2XUTA 4ZW9A 4XNJA 5C65A 4IKZA 4ZWCA 4U4WA 4TPGA 4U4VA 4D2CA 2CFPA 4YB9D 1PV7A 3O7QA 5D6KA 4D2BA 4U4TA 4YBQA 2V8NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4W6V A;  4IKX A;  4TPJ A;  4GBY A;  4TPH A;  4JA3 A;  4IKY A;  5A2O A;  5GXB A;  4IKV A;  4UVM A;  3O7P A;  1PW4 A;  4LEP A;  4OH3 A;  5EQI A;  4IU9 A;  4ZYR A;  4JRE A;  4QIQ A;  5A2N A;  4LDS A;  4XNI A;  2Y5Y A;  4JR9 A;  3WDO A;  5EQG A;  4PYP A;  5D59 A;  4APS A;  2CFQ A;  4IU8 A;  4J05 A;  4Q65 A;  4OAA A;  4GBZ A;  4GC0 A;  5EQH A;  5D58 A;  4D2D A;  4IKW A;  4ZWB A;  1PV6 A;  2XUT A;  4ZW9 A;  4XNJ A;  5C65 A;  4IKZ A;  4ZWC A;  4U4W A;  4TPG A;  4U4V A;  4D2C A;  2CFP A;  4YB9 D;  1PV7 A;  3O7Q A;  5D6K A;  4D2B A;  4U4T A;  4YBQ A;  2V8N A; 
#chains in the Genus database with same CATH topology
 4X51 A;  1RCB A;  4PS4 A;  3WCY I;  5C3E D;  3PIV A;  4NEJ A;  4XNI A;  1YKB A;  2B8X A;  4BXX D;  3HOY D;  3PO3 D;  1EVS A;  4XNJ A;  1D9C A;  2Z3R A;  3HOV D;  3D85 C;  3DI2 A;  4YPG C;  4DKE A;  1BCN A;  3BPL A;  2JA8 D;  5C7X A;  3DLQ I;  3G6D A;  1F45 B;  4A3J D;  4GRW A;  1GNC A;  4NI7 A;  2R92 D;  1ALU A;  5IYB D;  4Z5R D;  1Y6K L;  3INK C;  1RFB A;  1HWG A;  5D72 A;  4W6V A;  5D22 A;  1EXZ A;  1ITF A;  4ZYR A;  4BY1 D;  4QIQ A;  3HOX D;  4A3B D;  5D28 B;  3Q1S I;  4LDS A;  3IRH A;  5EQG A;  4NI9 A;  1HGU A;  4IU8 A;  4D2D A;  2B8U A;  3HHC A;  2B8Z A;  4A3E D;  5D6K A;  2INT A;  1INR A;  1BP3 A;  4IKY A;  1AXI A;  1EKU A;  4A3D D;  5KNH I;  4FA8 E;  5A2N A;  1PW6 A;  1M4B A;  4NKQ C;  1Y14 A;  1VLK A;  4Q65 A;  1Y6N L;  2R93 D;  4IKW A;  5L6Y C;  2JA5 D;  3HMX B;  1N1F A;  3SE4 B;  4TPH A;  1M4C A;  1HZI A;  2B90 A;  3UEZ E;  1RW5 A;  1WU3 I;  3QB1 A;  2ILK A;  2OQP A;  3N06 A;  1ILK A;  1J7V L;  4A3G D;  4A93 D;  1JLI A;  4U4W A;  4D2C A;  4O9H A;  2VUM D;  5E4E A;  3SE3 B;  4CNI C;  2KZ1 A;  2D48 A;  1IK0 A;  2B63 D;  4OH3 A;  3S9D A;  5FLM D;  1CNT 1;  1ITL A;  3WDO A;  5IYD D;  1CYL A;  4A3C D;  5D59 A;  3G9V B;  2Q7N B;  4BBR D;  5C65 A;  2XUT A;  1LKI A;  2B8Y A;  4U4T A;  1M49 A;  1SCF A;  3D48 P;  2L3Y A;  1M48 A;  1PGR A;  5LQB A;  3O7P A;  3NCC A;  1Z92 A;  5C4X D;  3VA2 A;  4JR9 A;  3HHR A;  4PYP A;  1P9M B;  4GC0 A;  1V7M V;  3BPO A;  4A3I D;  1IRL A;  5IYC D;  4D2B A;  3H3V E;  2Q14 A;  3UF5 A;  1BGC A;  1IJZ A;  3FKI D;  4YDY I;  1PW4 A;  3OQ3 A;  1HUL A;  1HUW A;  3QWR B;  2HYM B;  1A22 A;  2Y5Y A;  3NPZ A;  2B5I A;  5D58 A;  4NEM A;  4I77 Z;  4ZW9 A;  4A3F D;  4TPG A;  4YB9 D;  4TPJ A;  1Y6M L;  1HIK A;  3HOZ D;  3DI3 A;  1I1R B;  1ITM A;  3N0P A;  2E9W C;  1QVN A;  3L5X A;  5EQH A;  1KF9 A;  1PV6 A;  1PY2 A;  3D87 A;  2O6I A;  1LK3 A;  1M4A A;  4YBQ A;  3OG4 A;  1LQS L;  3LB6 B;  3OG6 A;  4WRL B;  4JA3 A;  3EJJ A;  3EW3 A;  1IAR A;  2B91 A;  4JRE A;  3UX9 A;  2JA7 D;  2XQB A;  2Q98 A;  5D71 A;  2O27 A;  4LRL A;  3I4M D;  4A3L D;  4DKD A;  2V8N A;  1CSG A;  3DGC L;  4IKV A;  4ZF7 A;  5EQI A;  2ERJ D;  1BGD A;  1Y1W D;  1Y1V D;  1NBP A;  1M4R A;  5A2O A;  2Z3Q A;  5GXB A;  1CN4 C;  1ITI A;  3NCE A;  1BUY A;  1EMR A;  4J05 A;  2LAG A;  3H0G D;  4DOH A;  1FYH A;  3B5K A;  1AU1 A;  2JA6 D;  3PO2 D;  3QAZ A;  5IP9 D;  3NCF A;  2IL6 A;  5TS9 A;  4YUE C;  1F6F A;  4YQX A;  2C35 A;  2R7Z D;  4NN6 A;  1ETE A;  4ZWC A;  2CFP A;  1V7N V;  3I4N D;  4IKX A;  2O26 A;  4GS7 A;  5D70 A;  2H24 A;  3QB7 A;  5IP7 D;  2LMS A;  1AX8 A;  3TGX B;  3AYH A;  3MZG A;  5FUC A;  4ZWB A;  4EXN A;  1M47 A;  1FG9 A;  4U4V A;  1HIJ A;  3O7Q A;  4J4L C;  1IL6 A;  2CYK A;  4UVM A;  3BES L;  2L3O A;  4LEP A;  1PVH B;  4NN7 A;  4MHL A;  4DKF A;  4ZS7 A;  1GA3 A;  1BGE A;  2PSM A;  3BPN A;  1BBN A;  4APS A;  3L5W I;  4OAA A;  5FHX A;  4IKZ A;  3UF2 A;  3HOU D;  3PIW A;  4GBY A;  4IU9 A;  3NCB A;  4BBS D;  4O6K A;  3LB6 A;  5C44 D;  2D9Q A;  3QT2 C;  4A3K D;  4EXP A;  2CFQ A;  4A3M D;  1HWH A;  4GBZ A;  3DUH C;  4RS1 A;  1RHG A;  4DKC A;  1D9G A;  4NN5 A;  1WCM D;  1CD9 A;  1Z7C A;  2GMF A;  1PV7 A;  3HOW D;  1A7M A;  1EER A;  1B5L A;  4BY7 D; 
#chains in the Genus database with same CATH homology
 4W6V A;  4IKX A;  4TPJ A;  4GBY A;  4TPH A;  4JA3 A;  4IKY A;  5A2O A;  5GXB A;  4IKV A;  4UVM A;  3O7P A;  1PW4 A;  4LEP A;  4OH3 A;  5EQI A;  4IU9 A;  4ZYR A;  4JRE A;  4QIQ A;  5A2N A;  4LDS A;  4XNI A;  2Y5Y A;  4JR9 A;  3WDO A;  5EQG A;  4PYP A;  5D59 A;  4APS A;  2CFQ A;  4IU8 A;  4J05 A;  4Q65 A;  4OAA A;  4GBZ A;  4GC0 A;  5EQH A;  5D58 A;  4D2D A;  4IKW A;  4ZWB A;  1PV6 A;  2XUT A;  4ZW9 A;  4XNJ A;  5C65 A;  4IKZ A;  4ZWC A;  4U4W A;  4TPG A;  4U4V A;  4D2C A;  2CFP A;  4YB9 D;  1PV7 A;  3O7Q A;  5D6K A;  4D2B A;  4U4T A;  4YBQ A;  2V8N A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...