4D2CA

Structure of a di peptide bound pot family peptide transporter
Total Genus 173
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
467
structure length
429
Chain Sequence
KTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Streptococcus thermophilus (strain atcc baa-250 / lmg 18311)
molecule keywords Di-or tripeptide:H+ symporter
total genus 173
structure length 429
sequence length 467
ec nomenclature
pdb deposition date 2014-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00854 PTR2 POT family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4d2cA00
3O7QA 4XNIA 4ZW9A 1PW4A 2V8NA 5D6KA 4TPHA 4YBQA 5GXBA 4APSA 5A2OA 4GBYA 4YB9D 1PV6A 4GC0A 4TPGA 2CFPA 4LEPA 4Q65A 5EQGA 4OH3A 3WDOA 4XNJA 2CFQA 4JR9A 4D2CA 4GBZA 4IKYA 4JA3A 4W6VA 5EQIA 4JREA 4IKVA 4D2BA 4IKWA 4U4WA 5C65A 4IKZA 4IU9A 4IKXA 4D2DA 2Y5YA 4TPJA 5D59A 4U4VA 4LDSA 4IU8A 4UVMA 4ZWBA 5A2NA 4QIQA 4U4TA 3O7PA 4ZWCA 4J05A 4PYPA 1PV7A 4ZYRA 5EQHA 2XUTA 4OAAA 5D58A
chains in the Genus database with same CATH superfamily
3HOZD 3DUHC 5A2OA 4I77Z 1ALUA 5C7XA 3QWRB 1ITLA 4NN5A 4OH3A 4A3JD 4A3BD 4IU9A 3D85C 1I1RB 3G6DA 3BPOA 5FHXA 4ZW9A 3UF2A 1Y6ML 2V8NA 2E9WC 1A7MA 1HULA 3PIVA 4NEJA 4Q65A 3TGXB 1SCFA 4RS1A 1EXZA 2HYMB 5L6YC 4ZYRA 3OG4A 3NCCA 3HMXB 1Y6KL 3PO3D 3OG6A 2B8YA 4DKEA 5C3ED 3I4ND 4JR9A 2O27A 1GA3A 4W6VA 3MZGA 4NI7A 1M4AA 2JA5D 3H3VE 2B8UA 3INKC 4DKFA 3DGCL 1PW4A 5C4XD 1CSGA 4EXPA 1CD9A 4YBQA 4GBYA 3IRHA 3HHRA 4PS4A 3D87A 1M48A 2CFQA 1ITMA 1F45B 4D2CA 1IRLA 3Q1SI 3VA2A 3S9DA 1ITFA 4UVMA 2B91A 4O9HA 1JLIA 3HHCA 2LMSA 3DI2A 1Y6NL 5LQBA 4EXNA 2O6IA 1RHGA 2H24A 4CNIC 4J4LC 3PIWA 4D2BA 1PY2A 4WRLB 1HGUA 1D9CA 5FLMD 1BGCA 5D59A 5TS9A 1BBNA 3B5KA 4A3MD 2ILKA 1M4CA 1NBPA 3OQ3A 1BP3A 1VLKA 2Z3QA 3HOYD 1HWHA 4BY1D 3HOUD 1PVHB 4LDSA 4IU8A 1CNT1 4NN7A 3LB6A 4BXXD 1INRA 1QVNA 3UX9A 1WU3I 1HZIA 2LAGA 1EVSA 3WCYI 5KNHI 4YPGC 3BPLA 4MHLA 1BGEA 5C65A 2R92D 4X51A 4GRWA 5D22A 4PYPA 4NN6A 2B5IA 2XQBA 4FA8E 4APSA 2Q98A 3I4MD 3N06A 1AX8A 1ETEA 5D71A 3HOWD 4QIQA 1BUYA 2O26A 3O7QA 2B63D 1WCMD 1Y14A 5IP9D 4TPHA 2JA6D 1Y1VD 1PV6A 1CYLA 3NPZA 5EQGA 1B5LA 4XNJA 1N1FA 4JREA 5IP7D 3N0PA 2D48A 3G9VB 4U4VA 2KZ1A 4ZF7A 2L3OA 1PGRA 4GS7A 1D9GA 4ZWCA 1M47A 2XUTA 1IL6A 1M4RA 1RW5A 1IJZA 3EW3A 3L5WI 3WDOA 1LKIA 4NEMA 4U4WA 1HIJA 3NCEA 2Q14A 1EMRA 4DKCA 3DI3A 3QB7A 4YB9D 4YQXA 3QT2C 1V7NV 4A3GD 3UEZE 1LQSL 1BGDA 3BESL 5GXBA 1KF9A 4TPGA 1P9MB 2JA7D 1A22A 4IKYA 3L5XA 5FUCA 4IKXA 1YKBA 4ZWBA 2CYKA 2B8ZA 1HWGA 3HOVD 1GNCA 3QAZA 5D58A 1ILKA 2Q7NB 1EERA 4Z5RD 1Z92A 2PSMA 4GC0A 3BPNA 3NCBA 2R93D 5EQIA 4ZS7A 1IARA 4IKWA 5E4EA 4IKZA 2VUMD 3NCFA 4U4TA 4YUEC 3H0GD 5EQHA 1BCNA 5D70A 4XNIA 3DLQI 1M49A 4A93D 5IYDD 3SE4B 2B90A 1M4BA 4A3DD 4BBRD 4IKVA 2R7ZD 4O6KA 1IK0A 1Z7CA 4J05A 1CN4C 2B8XA 4A3LD 4A3ID 2D9QA 4DOHA 2CFPA 5C44D 2L3YA 4NI9A 1FG9A 1PW6A 2Y5YA 3FKID 4BBSD 3UF5A 5A2NA 5IYCD 3SE3B 3O7PA 2IL6A 3AYHA 4A3ED 4NKQC 4LRLA 3HOXD 4A3CD 1V7MV 1HUWA 1AXIA 1AU1A 5IYBD 4A3KD 2GMFA 4D2DA 1HIKA 1EKUA 2OQPA 1RCBA 2C35A 5D72A 1ITIA 4YDYI 2INTA 5D6KA 1F6FA 3QB1A 4A3FD 4LEPA 1RFBA 2JA8D 4GBZA 1LK3A 4JA3A 1FYHA 3D48P 2Z3RA 4BY7D 1J7VL 3EJJA 4TPJA 4DKDA 1Y1WD 3PO2D 2ERJD 3LB6B 1PV7A 4OAAA 5D28B
chains in the Genus database with same CATH topology
3O7QA 4XNIA 4ZW9A 1PW4A 2V8NA 5D6KA 4TPHA 4YBQA 5GXBA 4APSA 5A2OA 4GBYA 4YB9D 1PV6A 4GC0A 4TPGA 2CFPA 4LEPA 4Q65A 5EQGA 4OH3A 3WDOA 4XNJA 2CFQA 4JR9A 4D2CA 4GBZA 4IKYA 4JA3A 4W6VA 5EQIA 4JREA 4IKVA 4D2BA 4IKWA 4U4WA 5C65A 4IKZA 4IU9A 4IKXA 4D2DA 2Y5YA 4TPJA 5D59A 4U4VA 4LDSA 4IU8A 4UVMA 4ZWBA 5A2NA 4QIQA 4U4TA 3O7PA 4ZWCA 4J05A 4PYPA 1PV7A 4ZYRA 5EQHA 2XUTA 4OAAA 5D58A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O7Q A;  4XNI A;  4ZW9 A;  1PW4 A;  2V8N A;  5D6K A;  4TPH A;  4YBQ A;  5GXB A;  4APS A;  5A2O A;  4GBY A;  4YB9 D;  1PV6 A;  4GC0 A;  4TPG A;  2CFP A;  4LEP A;  4Q65 A;  5EQG A;  4OH3 A;  3WDO A;  4XNJ A;  2CFQ A;  4JR9 A;  4D2C A;  4GBZ A;  4IKY A;  4JA3 A;  4W6V A;  5EQI A;  4JRE A;  4IKV A;  4D2B A;  4IKW A;  4U4W A;  5C65 A;  4IKZ A;  4IU9 A;  4IKX A;  4D2D A;  2Y5Y A;  4TPJ A;  5D59 A;  4U4V A;  4LDS A;  4IU8 A;  4UVM A;  4ZWB A;  5A2N A;  4QIQ A;  4U4T A;  3O7P A;  4ZWC A;  4J05 A;  4PYP A;  1PV7 A;  4ZYR A;  5EQH A;  2XUT A;  4OAA A;  5D58 A; 
#chains in the Genus database with same CATH topology
 3HOZ D;  3DUH C;  5A2O A;  4I77 Z;  1ALU A;  5C7X A;  3QWR B;  1ITL A;  4NN5 A;  4OH3 A;  4A3J D;  4A3B D;  4IU9 A;  3D85 C;  1I1R B;  3G6D A;  3BPO A;  5FHX A;  4ZW9 A;  3UF2 A;  1Y6M L;  2V8N A;  2E9W C;  1A7M A;  1HUL A;  3PIV A;  4NEJ A;  4Q65 A;  3TGX B;  1SCF A;  4RS1 A;  1EXZ A;  2HYM B;  5L6Y C;  4ZYR A;  3OG4 A;  3NCC A;  3HMX B;  1Y6K L;  3PO3 D;  3OG6 A;  2B8Y A;  4DKE A;  5C3E D;  3I4N D;  4JR9 A;  2O27 A;  1GA3 A;  4W6V A;  3MZG A;  4NI7 A;  1M4A A;  2JA5 D;  3H3V E;  2B8U A;  3INK C;  4DKF A;  3DGC L;  1PW4 A;  5C4X D;  1CSG A;  4EXP A;  1CD9 A;  4YBQ A;  4GBY A;  3IRH A;  3HHR A;  4PS4 A;  3D87 A;  1M48 A;  2CFQ A;  1ITM A;  1F45 B;  4D2C A;  1IRL A;  3Q1S I;  3VA2 A;  3S9D A;  1ITF A;  4UVM A;  2B91 A;  4O9H A;  1JLI A;  3HHC A;  2LMS A;  3DI2 A;  1Y6N L;  5LQB A;  4EXN A;  2O6I A;  1RHG A;  2H24 A;  4CNI C;  4J4L C;  3PIW A;  4D2B A;  1PY2 A;  4WRL B;  1HGU A;  1D9C A;  5FLM D;  1BGC A;  5D59 A;  5TS9 A;  1BBN A;  3B5K A;  4A3M D;  2ILK A;  1M4C A;  1NBP A;  3OQ3 A;  1BP3 A;  1VLK A;  2Z3Q A;  3HOY D;  1HWH A;  4BY1 D;  3HOU D;  1PVH B;  4LDS A;  4IU8 A;  1CNT 1;  4NN7 A;  3LB6 A;  4BXX D;  1INR A;  1QVN A;  3UX9 A;  1WU3 I;  1HZI A;  2LAG A;  1EVS A;  3WCY I;  5KNH I;  4YPG C;  3BPL A;  4MHL A;  1BGE A;  5C65 A;  2R92 D;  4X51 A;  4GRW A;  5D22 A;  4PYP A;  4NN6 A;  2B5I A;  2XQB A;  4FA8 E;  4APS A;  2Q98 A;  3I4M D;  3N06 A;  1AX8 A;  1ETE A;  5D71 A;  3HOW D;  4QIQ A;  1BUY A;  2O26 A;  3O7Q A;  2B63 D;  1WCM D;  1Y14 A;  5IP9 D;  4TPH A;  2JA6 D;  1Y1V D;  1PV6 A;  1CYL A;  3NPZ A;  5EQG A;  1B5L A;  4XNJ A;  1N1F A;  4JRE A;  5IP7 D;  3N0P A;  2D48 A;  3G9V B;  4U4V A;  2KZ1 A;  4ZF7 A;  2L3O A;  1PGR A;  4GS7 A;  1D9G A;  4ZWC A;  1M47 A;  2XUT A;  1IL6 A;  1M4R A;  1RW5 A;  1IJZ A;  3EW3 A;  3L5W I;  3WDO A;  1LKI A;  4NEM A;  4U4W A;  1HIJ A;  3NCE A;  2Q14 A;  1EMR A;  4DKC A;  3DI3 A;  3QB7 A;  4YB9 D;  4YQX A;  3QT2 C;  1V7N V;  4A3G D;  3UEZ E;  1LQS L;  1BGD A;  3BES L;  5GXB A;  1KF9 A;  4TPG A;  1P9M B;  2JA7 D;  1A22 A;  4IKY A;  3L5X A;  5FUC A;  4IKX A;  1YKB A;  4ZWB A;  2CYK A;  2B8Z A;  1HWG A;  3HOV D;  1GNC A;  3QAZ A;  5D58 A;  1ILK A;  2Q7N B;  1EER A;  4Z5R D;  1Z92 A;  2PSM A;  4GC0 A;  3BPN A;  3NCB A;  2R93 D;  5EQI A;  4ZS7 A;  1IAR A;  4IKW A;  5E4E A;  4IKZ A;  2VUM D;  3NCF A;  4U4T A;  4YUE C;  3H0G D;  5EQH A;  1BCN A;  5D70 A;  4XNI A;  3DLQ I;  1M49 A;  4A93 D;  5IYD D;  3SE4 B;  2B90 A;  1M4B A;  4A3D D;  4BBR D;  4IKV A;  2R7Z D;  4O6K A;  1IK0 A;  1Z7C A;  4J05 A;  1CN4 C;  2B8X A;  4A3L D;  4A3I D;  2D9Q A;  4DOH A;  2CFP A;  5C44 D;  2L3Y A;  4NI9 A;  1FG9 A;  1PW6 A;  2Y5Y A;  3FKI D;  4BBS D;  3UF5 A;  5A2N A;  5IYC D;  3SE3 B;  3O7P A;  2IL6 A;  3AYH A;  4A3E D;  4NKQ C;  4LRL A;  3HOX D;  4A3C D;  1V7M V;  1HUW A;  1AXI A;  1AU1 A;  5IYB D;  4A3K D;  2GMF A;  4D2D A;  1HIK A;  1EKU A;  2OQP A;  1RCB A;  2C35 A;  5D72 A;  1ITI A;  4YDY I;  2INT A;  5D6K A;  1F6F A;  3QB1 A;  4A3F D;  4LEP A;  1RFB A;  2JA8 D;  4GBZ A;  1LK3 A;  4JA3 A;  1FYH A;  3D48 P;  2Z3R A;  4BY7 D;  1J7V L;  3EJJ A;  4TPJ A;  4DKD A;  1Y1W D;  3PO2 D;  2ERJ D;  3LB6 B;  1PV7 A;  4OAA A;  5D28 B; 
#chains in the Genus database with same CATH homology
 3O7Q A;  4XNI A;  4ZW9 A;  1PW4 A;  2V8N A;  5D6K A;  4TPH A;  4YBQ A;  5GXB A;  4APS A;  5A2O A;  4GBY A;  4YB9 D;  1PV6 A;  4GC0 A;  4TPG A;  2CFP A;  4LEP A;  4Q65 A;  5EQG A;  4OH3 A;  3WDO A;  4XNJ A;  2CFQ A;  4JR9 A;  4D2C A;  4GBZ A;  4IKY A;  4JA3 A;  4W6V A;  5EQI A;  4JRE A;  4IKV A;  4D2B A;  4IKW A;  4U4W A;  5C65 A;  4IKZ A;  4IU9 A;  4IKX A;  4D2D A;  2Y5Y A;  4TPJ A;  5D59 A;  4U4V A;  4LDS A;  4IU8 A;  4UVM A;  4ZWB A;  5A2N A;  4QIQ A;  4U4T A;  3O7P A;  4ZWC A;  4J05 A;  4PYP A;  1PV7 A;  4ZYR A;  5EQH A;  2XUT A;  4OAA A;  5D58 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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