4IU9A

Crystal structure of a membrane transporter
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
443
structure length
396
Chain Sequence
LLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIALWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVILGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Escherichia coli
publication title Structure and mechanism of a nitrate transporter.
pubmed doi rcsb
molecule keywords Nitrite extrusion protein 2
total genus 123
structure length 396
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4iu9A00
4IKXA 5EQHA 4D2CA 2V8NA 4ZWBA 4IKZA 4D2DA 4OAAA 4IKVA 5A2OA 4ZYRA 2CFPA 4U4TA 5C65A 4YBQA 4TPJA 4IU8A 4U4WA 4XNIA 4GBZA 4PYPA 5GXBA 5D58A 4GC0A 4ZW9A 4OH3A 4XNJA 2XUTA 1PW4A 5EQGA 4APSA 4U4VA 1PV6A 4LDSA 5EQIA 5D59A 3WDOA 4TPHA 2CFQA 3O7PA 2Y5YA 4J05A 4YB9D 4UVMA 5D6KA 5A2NA 4IKYA 4Q65A 4ZWCA 3O7QA 4TPGA 4W6VA 4JR9A 4QIQA 4JA3A 4IKWA 1PV7A 4LEPA 4IU9A 4GBYA 4JREA 4D2BA
chains in the Genus database with same CATH superfamily
1ETEA 2B8UA 4NEJA 4NEMA 4YBQA 4EXNA 1LK3A 2B8XA 4YPGC 5GXBA 4BBSD 4OH3A 4APSA 1M47A 4BXXD 4PS4A 2E9WC 3WDOA 4MHLA 1INRA 3Q1SI 4A3LD 2C35A 3O7QA 1M49A 3VA2A 3DUHC 3S9DA 1ILKA 1AXIA 1BGDA 3N0PA 4UVMA 2PSMA 1PGRA 5TS9A 1IJZA 1M4BA 4JREA 3OG6A 1PY2A 3H0GD 3OG4A 1Y6ML 4YDYI 2B8ZA 2VUMD 4GS7A 5EQGA 1BUYA 5KNHI 1PV6A 4LDSA 1CD9A 5EQIA 3O7PA 4QIQA 1V7MV 5FUCA 2H24A 5EQHA 1Y1WD 2R93D 4GBZA 2O26A 4PYPA 4O9HA 1A7MA 2CFQA 3BPNA 3UF2A 3HOXD 1FG9A 3QAZA 1WU3I 2L3YA 3NCEA 2Q98A 4BY7D 2GMFA 3DLQI 5C44D 1Y6KL 3OQ3A 4NI7A 4U4VA 1IK0A 1N1FA 1P9MB 1JLIA 1HWHA 3D48P 1RHGA 1EVSA 1J7VL 3NCFA 3H3VE 2Q14A 3SE3B 4IKZA 5D71A 2B63D 4DKFA 4U4TA 3HHCA 4XNIA 5D22A 4GC0A 5FLMD 4XNJA 2HYMB 1V7NV 1Y1VD 1IRLA 1IARA 2IL6A 5IYDD 2INTA 5D72A 4YUEC 4ZWBA 1M48A 5L6YC 1ITMA 4DKCA 2R92D 3INKC 3SE4B 1D9CA 3I4ND 5D59A 1GNCA 1EXZA 1HGUA 3AYHA 3QWRB 1BCNA 4NI9A 1RW5A 5IP7D 5A2OA 3HOZD 4DOHA 2LMSA 3UF5A 4OAAA 5C3ED 3MZGA 1A22A 4ZYRA 3D85C 3L5XA 5D58A 2JA7D 2O6IA 2R7ZD 2LAGA 5LQBA 1ALUA 4J05A 5FHXA 3DI3A 4J4LC 5C7XA 4LRLA 3G6DA 4IU9A 1HIJA 4EXPA 3L5WI 2CYKA 4A3KD 1GA3A 4TPJA 1YKBA 1BP3A 3FKID 4WRLB 4A3GD 1M4CA 4NKQC 2Q7NB 5D70A 4A3ED 4GRWA 4NN7A 4W6VA 1HUWA 1F6FA 1RFBA 4GBYA 4NN5A 1CYLA 3PO3D 4BY1D 1AX8A 1Y6NL 4ZS7A 5C4XD 1EMRA 5IYBD 2XUTA 1PW4A 1Z92A 4RS1A 3EW3A 1ITLA 1CNT1 1I1RB 4A3JD 1LKIA 3DGCL 4D2CA 5E4EA 1Y14A 4A3MD 4Z5RD 3UEZE 3G9VB 3HOVD 5IP9D 3NCBA 2O27A 1SCFA 3HHRA 3HMXB 1HZIA 1EERA 3PIVA 4ZF7A 2B8YA 1CSGA 3EJJA 3PO2D 4A3ID 3B5KA 3LB6B 3PIWA 4CNIC 1BGCA 1EKUA 2Z3RA 3I4MD 5D6KA 4IKYA 1QVNA 2B5IA 4TPGA 4JA3A 1PV7A 2B90A 3NCCA 4X51A 3QB1A 4IKXA 2V8NA 4D2DA 3QB7A 1ITIA 1RCBA 2JA8D 5D28B 5C65A 4NN6A 4A3DD 5IYCD 4ZW9A 1FYHA 4O6KA 5A2NA 3UX9A 4DKEA 3LB6A 2JA5D 4LEPA 2XQBA 3HOWD 1BBNA 2Z3QA 1KF9A 3D87A 1PVHB 3BPLA 2ILKA 4BBRD 4TPHA 4Q65A 4ZWCA 1ITFA 1B5LA 1F45B 3QT2C 1LQSL 4A3BD 3BPOA 3NPZA 1Z7CA 4A93D 4U4WA 1HWGA 1IL6A 1PW6A 3BESL 3TGXB 1VLKA 2ERJD 1WCMD 3HOUD 3WCYI 2D9QA 4I77Z 3N06A 2Y5YA 4YB9D 2OQPA 4IKWA 2KZ1A 1NBPA 3DI2A 1HULA 4FA8E 4IKVA 1HIKA 1D9GA 2B91A 2CFPA 1CN4C 1M4RA 4IU8A 2D48A 2JA6D 1M4AA 4A3CD 3HOYD 4DKDA 2L3OA 4JR9A 1AU1A 1BGEA 4A3FD 3IRHA 4YQXA 4D2BA
chains in the Genus database with same CATH topology
4IKXA 5EQHA 4D2CA 2V8NA 4ZWBA 4IKZA 4D2DA 4OAAA 4IKVA 5A2OA 4ZYRA 2CFPA 4U4TA 5C65A 4YBQA 4TPJA 4IU8A 4U4WA 4XNIA 4GBZA 4PYPA 5GXBA 5D58A 4GC0A 4ZW9A 4OH3A 4XNJA 2XUTA 1PW4A 5EQGA 4APSA 4U4VA 1PV6A 4LDSA 5EQIA 5D59A 3WDOA 4TPHA 2CFQA 3O7PA 2Y5YA 4J05A 4YB9D 4UVMA 5D6KA 5A2NA 4IKYA 4Q65A 4ZWCA 3O7QA 4TPGA 4W6VA 4JR9A 4QIQA 4JA3A 4IKWA 1PV7A 4LEPA 4IU9A 4GBYA 4JREA 4D2BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKX A;  5EQH A;  4D2C A;  2V8N A;  4ZWB A;  4IKZ A;  4D2D A;  4OAA A;  4IKV A;  5A2O A;  4ZYR A;  2CFP A;  4U4T A;  5C65 A;  4YBQ A;  4TPJ A;  4IU8 A;  4U4W A;  4XNI A;  4GBZ A;  4PYP A;  5GXB A;  5D58 A;  4GC0 A;  4ZW9 A;  4OH3 A;  4XNJ A;  2XUT A;  1PW4 A;  5EQG A;  4APS A;  4U4V A;  1PV6 A;  4LDS A;  5EQI A;  5D59 A;  3WDO A;  4TPH A;  2CFQ A;  3O7P A;  2Y5Y A;  4J05 A;  4YB9 D;  4UVM A;  5D6K A;  5A2N A;  4IKY A;  4Q65 A;  4ZWC A;  3O7Q A;  4TPG A;  4W6V A;  4JR9 A;  4QIQ A;  4JA3 A;  4IKW A;  1PV7 A;  4LEP A;  4IU9 A;  4GBY A;  4JRE A;  4D2B A; 
#chains in the Genus database with same CATH topology
 1ETE A;  2B8U A;  4NEJ A;  4NEM A;  4YBQ A;  4EXN A;  1LK3 A;  2B8X A;  4YPG C;  5GXB A;  4BBS D;  4OH3 A;  4APS A;  1M47 A;  4BXX D;  4PS4 A;  2E9W C;  3WDO A;  4MHL A;  1INR A;  3Q1S I;  4A3L D;  2C35 A;  3O7Q A;  1M49 A;  3VA2 A;  3DUH C;  3S9D A;  1ILK A;  1AXI A;  1BGD A;  3N0P A;  4UVM A;  2PSM A;  1PGR A;  5TS9 A;  1IJZ A;  1M4B A;  4JRE A;  3OG6 A;  1PY2 A;  3H0G D;  3OG4 A;  1Y6M L;  4YDY I;  2B8Z A;  2VUM D;  4GS7 A;  5EQG A;  1BUY A;  5KNH I;  1PV6 A;  4LDS A;  1CD9 A;  5EQI A;  3O7P A;  4QIQ A;  1V7M V;  5FUC A;  2H24 A;  5EQH A;  1Y1W D;  2R93 D;  4GBZ A;  2O26 A;  4PYP A;  4O9H A;  1A7M A;  2CFQ A;  3BPN A;  3UF2 A;  3HOX D;  1FG9 A;  3QAZ A;  1WU3 I;  2L3Y A;  3NCE A;  2Q98 A;  4BY7 D;  2GMF A;  3DLQ I;  5C44 D;  1Y6K L;  3OQ3 A;  4NI7 A;  4U4V A;  1IK0 A;  1N1F A;  1P9M B;  1JLI A;  1HWH A;  3D48 P;  1RHG A;  1EVS A;  1J7V L;  3NCF A;  3H3V E;  2Q14 A;  3SE3 B;  4IKZ A;  5D71 A;  2B63 D;  4DKF A;  4U4T A;  3HHC A;  4XNI A;  5D22 A;  4GC0 A;  5FLM D;  4XNJ A;  2HYM B;  1V7N V;  1Y1V D;  1IRL A;  1IAR A;  2IL6 A;  5IYD D;  2INT A;  5D72 A;  4YUE C;  4ZWB A;  1M48 A;  5L6Y C;  1ITM A;  4DKC A;  2R92 D;  3INK C;  3SE4 B;  1D9C A;  3I4N D;  5D59 A;  1GNC A;  1EXZ A;  1HGU A;  3AYH A;  3QWR B;  1BCN A;  4NI9 A;  1RW5 A;  5IP7 D;  5A2O A;  3HOZ D;  4DOH A;  2LMS A;  3UF5 A;  4OAA A;  5C3E D;  3MZG A;  1A22 A;  4ZYR A;  3D85 C;  3L5X A;  5D58 A;  2JA7 D;  2O6I A;  2R7Z D;  2LAG A;  5LQB A;  1ALU A;  4J05 A;  5FHX A;  3DI3 A;  4J4L C;  5C7X A;  4LRL A;  3G6D A;  4IU9 A;  1HIJ A;  4EXP A;  3L5W I;  2CYK A;  4A3K D;  1GA3 A;  4TPJ A;  1YKB A;  1BP3 A;  3FKI D;  4WRL B;  4A3G D;  1M4C A;  4NKQ C;  2Q7N B;  5D70 A;  4A3E D;  4GRW A;  4NN7 A;  4W6V A;  1HUW A;  1F6F A;  1RFB A;  4GBY A;  4NN5 A;  1CYL A;  3PO3 D;  4BY1 D;  1AX8 A;  1Y6N L;  4ZS7 A;  5C4X D;  1EMR A;  5IYB D;  2XUT A;  1PW4 A;  1Z92 A;  4RS1 A;  3EW3 A;  1ITL A;  1CNT 1;  1I1R B;  4A3J D;  1LKI A;  3DGC L;  4D2C A;  5E4E A;  1Y14 A;  4A3M D;  4Z5R D;  3UEZ E;  3G9V B;  3HOV D;  5IP9 D;  3NCB A;  2O27 A;  1SCF A;  3HHR A;  3HMX B;  1HZI A;  1EER A;  3PIV A;  4ZF7 A;  2B8Y A;  1CSG A;  3EJJ A;  3PO2 D;  4A3I D;  3B5K A;  3LB6 B;  3PIW A;  4CNI C;  1BGC A;  1EKU A;  2Z3R A;  3I4M D;  5D6K A;  4IKY A;  1QVN A;  2B5I A;  4TPG A;  4JA3 A;  1PV7 A;  2B90 A;  3NCC A;  4X51 A;  3QB1 A;  4IKX A;  2V8N A;  4D2D A;  3QB7 A;  1ITI A;  1RCB A;  2JA8 D;  5D28 B;  5C65 A;  4NN6 A;  4A3D D;  5IYC D;  4ZW9 A;  1FYH A;  4O6K A;  5A2N A;  3UX9 A;  4DKE A;  3LB6 A;  2JA5 D;  4LEP A;  2XQB A;  3HOW D;  1BBN A;  2Z3Q A;  1KF9 A;  3D87 A;  1PVH B;  3BPL A;  2ILK A;  4BBR D;  4TPH A;  4Q65 A;  4ZWC A;  1ITF A;  1B5L A;  1F45 B;  3QT2 C;  1LQS L;  4A3B D;  3BPO A;  3NPZ A;  1Z7C A;  4A93 D;  4U4W A;  1HWG A;  1IL6 A;  1PW6 A;  3BES L;  3TGX B;  1VLK A;  2ERJ D;  1WCM D;  3HOU D;  3WCY I;  2D9Q A;  4I77 Z;  3N06 A;  2Y5Y A;  4YB9 D;  2OQP A;  4IKW A;  2KZ1 A;  1NBP A;  3DI2 A;  1HUL A;  4FA8 E;  4IKV A;  1HIK A;  1D9G A;  2B91 A;  2CFP A;  1CN4 C;  1M4R A;  4IU8 A;  2D48 A;  2JA6 D;  1M4A A;  4A3C D;  3HOY D;  4DKD A;  2L3O A;  4JR9 A;  1AU1 A;  1BGE A;  4A3F D;  3IRH A;  4YQX A;  4D2B A; 
#chains in the Genus database with same CATH homology
 4IKX A;  5EQH A;  4D2C A;  2V8N A;  4ZWB A;  4IKZ A;  4D2D A;  4OAA A;  4IKV A;  5A2O A;  4ZYR A;  2CFP A;  4U4T A;  5C65 A;  4YBQ A;  4TPJ A;  4IU8 A;  4U4W A;  4XNI A;  4GBZ A;  4PYP A;  5GXB A;  5D58 A;  4GC0 A;  4ZW9 A;  4OH3 A;  4XNJ A;  2XUT A;  1PW4 A;  5EQG A;  4APS A;  4U4V A;  1PV6 A;  4LDS A;  5EQI A;  5D59 A;  3WDO A;  4TPH A;  2CFQ A;  3O7P A;  2Y5Y A;  4J05 A;  4YB9 D;  4UVM A;  5D6K A;  5A2N A;  4IKY A;  4Q65 A;  4ZWC A;  3O7Q A;  4TPG A;  4W6V A;  4JR9 A;  4QIQ A;  4JA3 A;  4IKW A;  1PV7 A;  4LEP A;  4IU9 A;  4GBY A;  4JRE A;  4D2B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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