4IU9A

Crystal structure of a membrane transporter
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
443
structure length
396
Chain Sequence
LLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIALWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVILGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of a nitrate transporter.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords Nitrite extrusion protein 2
total genus 123
structure length 396
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4iu9A00
4Q65A 5EQGA 4YBQA 4IKYA 4J05A 4XNJA 4D2CA 2CFPA 1PV7A 4QIQA 4IU9A 4U4VA 4IKXA 4W6VA 4U4TA 4PYPA 4D2DA 4ZWBA 5A2NA 4GBYA 3O7PA 4APSA 4XNIA 4TPJA 1PV6A 4U4WA 4UVMA 4TPHA 4ZW9A 5EQHA 4IKWA 4IU8A 1PW4A 4D2BA 4ZYRA 2V8NA 2XUTA 4IKZA 2CFQA 4OAAA 5A2OA 2Y5YA 3WDOA 4LEPA 4GC0A 4JA3A 5C65A 5EQIA 4ZWCA 4GBZA 4IKVA 4OH3A 5D59A 5D6KA 4JREA 5GXBA 4JR9A 5D58A 4LDSA 4YB9D 3O7QA 4TPGA
chains in the Genus database with same CATH superfamily
2KZ1A 2ERJD 2LMSA 3DI2A 5LQBA 5D72A 1FG9A 1PY2A 3NCCA 1LKIA 1ITLA 4YQXA 4GC0A 5C65A 4O6KA 1BP3A 1IRLA 1EERA 4A3ID 1HIJA 5EQGA 2Q98A 1I1RB 1CN4C 1CNT1 4DKFA 3TGXB 3SE4B 1Y6NL 4A3JD 1P9MB 3UX9A 4GS7A 1AXIA 2HYMB 4BY7D 2IL6A 4GBZA 4YDYI 3SE3B 4TPGA 1QVNA 3HOXD 2B90A 1M4AA 3G6DA 5TS9A 4A3CD 5EQHA 4IU8A 1PW4A 2R93D 4BY1D 2Y5YA 5EQIA 1BBNA 5KNHI 3I4ND 4NEMA 4NKQC 1SCFA 1BCNA 2E9WC 1IJZA 4RS1A 4A3MD 4YPGC 1Y14A 4EXNA 3N06A 1RW5A 1CYLA 3PIVA 3BPNA 3QAZA 3LB6A 3VA2A 1M4CA 4LDSA 4YB9D 5D58A 2Q14A 1WCMD 4D2CA 4I77Z 1PV7A 2B8UA 1EVSA 1BGEA 2B8XA 1JLIA 3QT2C 2OQPA 5A2OA 5IYCD 5GXBA 2VUMD 4JR9A 3QWRB 2H24A 4Z5RD 4YBQA 4GRWA 2GMFA 4BBRD 5IYBD 3H3VE 3OQ3A 3HHCA 5C44D 1BUYA 4NI7A 1RCBA 5FHXA 4LRLA 1M49A 2JA6D 3UEZE 1HIKA 1AX8A 3QB1A 1Y6KL 3DGCL 3PO3D 2CYKA 5A2NA 1CSGA 1BGCA 3O7PA 3PIWA 4XNIA 4A3ED 4IKWA 3UF2A 3BPLA 2V8NA 1HULA 2R7ZD 2O27A 1ILKA 1IK0A 3FKID 3BPOA 5D59A 4J4LC 2B5IA 3QB7A 4BXXD 2LAGA 1D9CA 4A93D 4U4VA 1Y1WD 4TPJA 3NCEA 1PV6A 1GA3A 3HMXB 3S9DA 4A3FD 3DI3A 3WDOA 5D6KA 5C7XA 4WRLB 1KF9A 3D85C 4PS4A 1CD9A 1RFBA 2B63D 4U4WA 3LB6B 1Z7CA 3HOWD 4OAAA 3NCFA 3HOZD 1EMRA 4CNIC 1N1FA 3EJJA 4FA8E 1HZIA 5C3ED 1RHGA 1AU1A 4X51A 4DKCA 4NN5A 4QIQA 4IU9A 4U4TA 4NN7A 4APSA 1ALUA 2L3OA 4TPHA 4ZW9A 3D87A 3DLQI 4ZYRA 3DUHC 1IL6A 1IARA 5FLMD 1LK3A 4A3LD 4Q65A 1B5LA 5D70A 2R92D 1ITMA 4W6VA 2C35A 4IKXA 1F6FA 4D2DA 1D9GA 4EXPA 4DKDA 3PO2D 5IP9D 1GNCA 1ITFA 4A3GD 3AYHA 2CFQA 4A3KD 2XQBA 4ZS7A 5D71A 2O6IA 4IKVA 2JA7D 4DOHA 3N0PA 2PSMA 1NBPA 3Q1SI 1A7MA 2CFPA 1V7MV 3OG4A 4DKEA 1YKBA 3BESL 5IYDD 4GBYA 4NI9A 1V7NV 3D48P 1HGUA 1BGDA 1M48A 3WCYI 1LQSL 5FUCA 3UF5A 1M4BA 4LEPA 3MZGA 3IRHA 4JA3A 1PVHB 3G9VB 3L5XA 1PGRA 4XNJA 3NPZA 1A22A 3HHRA 3L5WI 4BBSD 3NCBA 5C4XD 2JA5D 4NN6A 2ILKA 3EW3A 4A3BD 3INKC 4IKYA 4J05A 5IP7D 3OG6A 1J7VL 5D28B 4ZWBA 4UVMA 4D2BA 2B8YA 4IKZA 1M4RA 1Y6ML 3I4MD 1M47A 1EKUA 2B91A 4JREA 2Z3QA 1FYHA 1ETEA 5L6YC 3B5KA 1WU3I 2JA8D 3H0GD 4PYPA 1VLKA 3HOVD 4ZF7A 1EXZA 2Q7NB 2D48A 2L3YA 2XUTA 5D22A 1HWHA 4NEJA 4ZWCA 1Y1VD 1INRA 2O26A 1HUWA 3HOUD 4YUEC 1ITIA 2B8ZA 3HOYD 1PW6A 5E4EA 2INTA 2Z3RA 4MHLA 4A3DD 2D9QA 4O9HA 1Z92A 1F45B 4OH3A 1HWGA 3O7QA
chains in the Genus database with same CATH topology
4Q65A 5EQGA 4YBQA 4IKYA 4J05A 4XNJA 4D2CA 2CFPA 1PV7A 4QIQA 4IU9A 4U4VA 4IKXA 4W6VA 4U4TA 4PYPA 4D2DA 4ZWBA 5A2NA 4GBYA 3O7PA 4APSA 4XNIA 4TPJA 1PV6A 4U4WA 4UVMA 4TPHA 4ZW9A 5EQHA 4IKWA 4IU8A 1PW4A 4D2BA 4ZYRA 2V8NA 2XUTA 4IKZA 2CFQA 4OAAA 5A2OA 2Y5YA 3WDOA 4LEPA 4GC0A 4JA3A 5C65A 5EQIA 4ZWCA 4GBZA 4IKVA 4OH3A 5D59A 5D6KA 4JREA 5GXBA 4JR9A 5D58A 4LDSA 4YB9D 3O7QA 4TPGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q65 A;  5EQG A;  4YBQ A;  4IKY A;  4J05 A;  4XNJ A;  4D2C A;  2CFP A;  1PV7 A;  4QIQ A;  4IU9 A;  4U4V A;  4IKX A;  4W6V A;  4U4T A;  4PYP A;  4D2D A;  4ZWB A;  5A2N A;  4GBY A;  3O7P A;  4APS A;  4XNI A;  4TPJ A;  1PV6 A;  4U4W A;  4UVM A;  4TPH A;  4ZW9 A;  5EQH A;  4IKW A;  4IU8 A;  1PW4 A;  4D2B A;  4ZYR A;  2V8N A;  2XUT A;  4IKZ A;  2CFQ A;  4OAA A;  5A2O A;  2Y5Y A;  3WDO A;  4LEP A;  4GC0 A;  4JA3 A;  5C65 A;  5EQI A;  4ZWC A;  4GBZ A;  4IKV A;  4OH3 A;  5D59 A;  5D6K A;  4JRE A;  5GXB A;  4JR9 A;  5D58 A;  4LDS A;  4YB9 D;  3O7Q A;  4TPG A; 
#chains in the Genus database with same CATH topology
 2KZ1 A;  2ERJ D;  2LMS A;  3DI2 A;  5LQB A;  5D72 A;  1FG9 A;  1PY2 A;  3NCC A;  1LKI A;  1ITL A;  4YQX A;  4GC0 A;  5C65 A;  4O6K A;  1BP3 A;  1IRL A;  1EER A;  4A3I D;  1HIJ A;  5EQG A;  2Q98 A;  1I1R B;  1CN4 C;  1CNT 1;  4DKF A;  3TGX B;  3SE4 B;  1Y6N L;  4A3J D;  1P9M B;  3UX9 A;  4GS7 A;  1AXI A;  2HYM B;  4BY7 D;  2IL6 A;  4GBZ A;  4YDY I;  3SE3 B;  4TPG A;  1QVN A;  3HOX D;  2B90 A;  1M4A A;  3G6D A;  5TS9 A;  4A3C D;  5EQH A;  4IU8 A;  1PW4 A;  2R93 D;  4BY1 D;  2Y5Y A;  5EQI A;  1BBN A;  5KNH I;  3I4N D;  4NEM A;  4NKQ C;  1SCF A;  1BCN A;  2E9W C;  1IJZ A;  4RS1 A;  4A3M D;  4YPG C;  1Y14 A;  4EXN A;  3N06 A;  1RW5 A;  1CYL A;  3PIV A;  3BPN A;  3QAZ A;  3LB6 A;  3VA2 A;  1M4C A;  4LDS A;  4YB9 D;  5D58 A;  2Q14 A;  1WCM D;  4D2C A;  4I77 Z;  1PV7 A;  2B8U A;  1EVS A;  1BGE A;  2B8X A;  1JLI A;  3QT2 C;  2OQP A;  5A2O A;  5IYC D;  5GXB A;  2VUM D;  4JR9 A;  3QWR B;  2H24 A;  4Z5R D;  4YBQ A;  4GRW A;  2GMF A;  4BBR D;  5IYB D;  3H3V E;  3OQ3 A;  3HHC A;  5C44 D;  1BUY A;  4NI7 A;  1RCB A;  5FHX A;  4LRL A;  1M49 A;  2JA6 D;  3UEZ E;  1HIK A;  1AX8 A;  3QB1 A;  1Y6K L;  3DGC L;  3PO3 D;  2CYK A;  5A2N A;  1CSG A;  1BGC A;  3O7P A;  3PIW A;  4XNI A;  4A3E D;  4IKW A;  3UF2 A;  3BPL A;  2V8N A;  1HUL A;  2R7Z D;  2O27 A;  1ILK A;  1IK0 A;  3FKI D;  3BPO A;  5D59 A;  4J4L C;  2B5I A;  3QB7 A;  4BXX D;  2LAG A;  1D9C A;  4A93 D;  4U4V A;  1Y1W D;  4TPJ A;  3NCE A;  1PV6 A;  1GA3 A;  3HMX B;  3S9D A;  4A3F D;  3DI3 A;  3WDO A;  5D6K A;  5C7X A;  4WRL B;  1KF9 A;  3D85 C;  4PS4 A;  1CD9 A;  1RFB A;  2B63 D;  4U4W A;  3LB6 B;  1Z7C A;  3HOW D;  4OAA A;  3NCF A;  3HOZ D;  1EMR A;  4CNI C;  1N1F A;  3EJJ A;  4FA8 E;  1HZI A;  5C3E D;  1RHG A;  1AU1 A;  4X51 A;  4DKC A;  4NN5 A;  4QIQ A;  4IU9 A;  4U4T A;  4NN7 A;  4APS A;  1ALU A;  2L3O A;  4TPH A;  4ZW9 A;  3D87 A;  3DLQ I;  4ZYR A;  3DUH C;  1IL6 A;  1IAR A;  5FLM D;  1LK3 A;  4A3L D;  4Q65 A;  1B5L A;  5D70 A;  2R92 D;  1ITM A;  4W6V A;  2C35 A;  4IKX A;  1F6F A;  4D2D A;  1D9G A;  4EXP A;  4DKD A;  3PO2 D;  5IP9 D;  1GNC A;  1ITF A;  4A3G D;  3AYH A;  2CFQ A;  4A3K D;  2XQB A;  4ZS7 A;  5D71 A;  2O6I A;  4IKV A;  2JA7 D;  4DOH A;  3N0P A;  2PSM A;  1NBP A;  3Q1S I;  1A7M A;  2CFP A;  1V7M V;  3OG4 A;  4DKE A;  1YKB A;  3BES L;  5IYD D;  4GBY A;  4NI9 A;  1V7N V;  3D48 P;  1HGU A;  1BGD A;  1M48 A;  3WCY I;  1LQS L;  5FUC A;  3UF5 A;  1M4B A;  4LEP A;  3MZG A;  3IRH A;  4JA3 A;  1PVH B;  3G9V B;  3L5X A;  1PGR A;  4XNJ A;  3NPZ A;  1A22 A;  3HHR A;  3L5W I;  4BBS D;  3NCB A;  5C4X D;  2JA5 D;  4NN6 A;  2ILK A;  3EW3 A;  4A3B D;  3INK C;  4IKY A;  4J05 A;  5IP7 D;  3OG6 A;  1J7V L;  5D28 B;  4ZWB A;  4UVM A;  4D2B A;  2B8Y A;  4IKZ A;  1M4R A;  1Y6M L;  3I4M D;  1M47 A;  1EKU A;  2B91 A;  4JRE A;  2Z3Q A;  1FYH A;  1ETE A;  5L6Y C;  3B5K A;  1WU3 I;  2JA8 D;  3H0G D;  4PYP A;  1VLK A;  3HOV D;  4ZF7 A;  1EXZ A;  2Q7N B;  2D48 A;  2L3Y A;  2XUT A;  5D22 A;  1HWH A;  4NEJ A;  4ZWC A;  1Y1V D;  1INR A;  2O26 A;  1HUW A;  3HOU D;  4YUE C;  1ITI A;  2B8Z A;  3HOY D;  1PW6 A;  5E4E A;  2INT A;  2Z3R A;  4MHL A;  4A3D D;  2D9Q A;  4O9H A;  1Z92 A;  1F45 B;  4OH3 A;  1HWG A;  3O7Q A; 
#chains in the Genus database with same CATH homology
 4Q65 A;  5EQG A;  4YBQ A;  4IKY A;  4J05 A;  4XNJ A;  4D2C A;  2CFP A;  1PV7 A;  4QIQ A;  4IU9 A;  4U4V A;  4IKX A;  4W6V A;  4U4T A;  4PYP A;  4D2D A;  4ZWB A;  5A2N A;  4GBY A;  3O7P A;  4APS A;  4XNI A;  4TPJ A;  1PV6 A;  4U4W A;  4UVM A;  4TPH A;  4ZW9 A;  5EQH A;  4IKW A;  4IU8 A;  1PW4 A;  4D2B A;  4ZYR A;  2V8N A;  2XUT A;  4IKZ A;  2CFQ A;  4OAA A;  5A2O A;  2Y5Y A;  3WDO A;  4LEP A;  4GC0 A;  4JA3 A;  5C65 A;  5EQI A;  4ZWC A;  4GBZ A;  4IKV A;  4OH3 A;  5D59 A;  5D6K A;  4JRE A;  5GXB A;  4JR9 A;  5D58 A;  4LDS A;  4YB9 D;  3O7Q A;  4TPG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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