4IU9A

Crystal structure of a membrane transporter
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
443
structure length
396
Chain Sequence
LLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIALWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVILGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of a nitrate transporter.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords Nitrite extrusion protein 2
total genus 123
structure length 396
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4iu9A00
4OAAA 4TPGA 4JR9A 2Y5YA 4GC0A 4IKVA 4Q65A 4D2CA 4YBQA 3O7QA 4W6VA 5GXBA 4U4VA 4IU9A 5C65A 4XNJA 4J05A 4GBZA 4IKXA 5EQIA 4ZWCA 2V8NA 4IKYA 4ZYRA 5D58A 5EQGA 4IU8A 4ZWBA 4PYPA 1PV7A 4IKWA 4QIQA 4JA3A 1PW4A 4ZW9A 4XNIA 4D2DA 4D2BA 3O7PA 1PV6A 3WDOA 4UVMA 5A2OA 2XUTA 2CFPA 5D6KA 5EQHA 4JREA 4OH3A 4U4WA 4U4TA 4TPHA 4LDSA 4GBYA 5A2NA 4LEPA 4APSA 2CFQA 5D59A 4TPJA 4YB9D 4IKZA
chains in the Genus database with same CATH superfamily
1FG9A 4TPGA 5GXBA 1IL6A 4U4VA 4GS7A 1V7NV 3UX9A 3HOXD 3VA2A 3PIWA 1ITLA 1M4AA 3DI2A 1HZIA 1QVNA 4LDSA 5IYBD 1FYHA 2JA5D 3QB1A 1PGRA 1M4RA 4J05A 1ITMA 5IP9D 3N06A 4BBRD 4NKQC 3G6DA 3H3VE 5FUCA 3D48P 2PSMA 2GMFA 4NI7A 5C7XA 4TPJA 4YB9D 1ALUA 3PO2D 3N0PA 5D71A 3TGXB 1PW6A 1GA3A 2R92D 2D9QA 5EQIA 2R93D 1PV7A 1P9MB 3O7PA 1Y14A 4BBSD 5IYDD 5A2OA 1LKIA 5C4XD 1EXZA 3AYHA 1HULA 2B63D 2B5IA 1ITIA 4O9HA 2Q7NB 3O7QA 4CNIC 3SE4B 2ERJD 4J4LC 4DKFA 4D2BA 1AXIA 2JA6D 2JA8D 3DUHC 2O6IA 1CD9A 4GBYA 4A3BD 3HOZD 3D85C 1Y6NL 4LRLA 3OG6A 5C44D 1Y6KL 1ETEA 4Z5RD 4ZW9A 1M48A 4YDYI 3L5XA 1M49A 1M4BA 1RFBA 3MZGA 5D6KA 4U4WA 1HGUA 3NPZA 4DKCA 4RS1A 2B90A 2CYKA 4NI9A 2Z3QA 2IL6A 1M4CA 1CSGA 4X51A 2JA7D 4ZWCA 1BCNA 4ZWBA 4IKWA 5TS9A 1RCBA 2OQPA 1INRA 4UVMA 2CFPA 4OH3A 4YQXA 2Q98A 3FKID 5L6YC 4A3JD 3I4MD 1RHGA 2D48A 4Q65A 3EJJA 1CN4C 2L3YA 4FA8E 2O26A 4NN7A 2R7ZD 4WRLB 3HMXB 3HHRA 4APSA 1A22A 2C35A 2H24A 1F45B 1Z7CA 4DKDA 3EW3A 4IKVA 5D72A 2Q14A 4IU9A 5D58A 4A3DD 4IU8A 1HUWA 4A3LD 4D2DA 1BP3A 1AX8A 5EQHA 4TPHA 4BY7D 1HIJA 1CNT1 5FLMD 5IP7D 4GC0A 1V7MV 4PS4A 1WU3I 3DI3A 3D87A 4MHLA 4IKXA 3UEZE 4ZYRA 1LK3A 3BPLA 4U4TA 3PIVA 3NCBA 1A7MA 4YUEC 3QAZA 1AU1A 1EKUA 4IKZA 4EXPA 1YKBA 2ILKA 4ZS7A 3HOUD 5EQGA 4A3FD 4PYPA 1D9CA 2O27A 3NCFA 4A3ID 3OQ3A 1BGCA 3NCEA 4O6KA 3WCYI 1WCMD 1F6FA 3BPOA 5A2NA 2CFQA 1BGEA 3DGCL 2VUMD 4NN5A 5C65A 4A3GD 3OG4A 1CYLA 1SCFA 4JA3A 1Y1VD 4XNIA 3HOVD 2XUTA 1IK0A 4JREA 4A93D 1IRLA 3H0GD 1D9GA 1ITFA 3SE3B 3NCCA 4OAAA 4JR9A 4D2CA 4YBQA 1ILKA 2L3OA 4IKYA 1JLIA 3BPNA 3UF5A 4BY1D 1HWGA 1NBPA 1EMRA 4DOHA 3LB6B 5LQBA 2B8XA 1HIKA 2B8ZA 3LB6A 2Y5YA 1BBNA 4W6VA 1EERA 3HOYD 4A3ED 5E4EA 2LAGA 3QT2C 1B5LA 1Y1WD 4NEMA 1HWHA 3UF2A 1EVSA 3BESL 5D59A 4NEJA 1PVHB 1N1FA 2KZ1A 4BXXD 3QB7A 1M47A 5D70A 2XQBA 4DKEA 1PW4A 5IYCD 4EXNA 4A3KD 1GNCA 2INTA 3IRHA 3HOWD 3Q1SI 2B8UA 4XNJA 4GBZA 3S9DA 2LMSA 5KNHI 1BUYA 1Y6ML 1BGDA 2E9WC 1Z92A 4I77Z 2Z3RA 1KF9A 4YPGC 2B8YA 3INKC 4A3CD 1IJZA 4GRWA 5D22A 5C3ED 1LQSL 1PY2A 1J7VL 3B5KA 5D28B 2B91A 3I4ND 2V8NA 3HHCA 4QIQA 1IARA 1PV6A 5FHXA 3L5WI 3WDOA 1VLKA 3DLQI 1RW5A 3QWRB 4NN6A 4A3MD 4LEPA 3PO3D 4ZF7A 3G9VB 2HYMB 1I1RB
chains in the Genus database with same CATH topology
4OAAA 4TPGA 4JR9A 2Y5YA 4GC0A 4IKVA 4Q65A 4D2CA 4YBQA 3O7QA 4W6VA 5GXBA 4U4VA 4IU9A 5C65A 4XNJA 4J05A 4GBZA 4IKXA 5EQIA 4ZWCA 2V8NA 4IKYA 4ZYRA 5D58A 5EQGA 4IU8A 4ZWBA 4PYPA 1PV7A 4IKWA 4QIQA 4JA3A 1PW4A 4ZW9A 4XNIA 4D2DA 4D2BA 3O7PA 1PV6A 3WDOA 4UVMA 5A2OA 2XUTA 2CFPA 5D6KA 5EQHA 4JREA 4OH3A 4U4WA 4U4TA 4TPHA 4LDSA 4GBYA 5A2NA 4LEPA 4APSA 2CFQA 5D59A 4TPJA 4YB9D 4IKZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OAA A;  4TPG A;  4JR9 A;  2Y5Y A;  4GC0 A;  4IKV A;  4Q65 A;  4D2C A;  4YBQ A;  3O7Q A;  4W6V A;  5GXB A;  4U4V A;  4IU9 A;  5C65 A;  4XNJ A;  4J05 A;  4GBZ A;  4IKX A;  5EQI A;  4ZWC A;  2V8N A;  4IKY A;  4ZYR A;  5D58 A;  5EQG A;  4IU8 A;  4ZWB A;  4PYP A;  1PV7 A;  4IKW A;  4QIQ A;  4JA3 A;  1PW4 A;  4ZW9 A;  4XNI A;  4D2D A;  4D2B A;  3O7P A;  1PV6 A;  3WDO A;  4UVM A;  5A2O A;  2XUT A;  2CFP A;  5D6K A;  5EQH A;  4JRE A;  4OH3 A;  4U4W A;  4U4T A;  4TPH A;  4LDS A;  4GBY A;  5A2N A;  4LEP A;  4APS A;  2CFQ A;  5D59 A;  4TPJ A;  4YB9 D;  4IKZ A; 
#chains in the Genus database with same CATH topology
 1FG9 A;  4TPG A;  5GXB A;  1IL6 A;  4U4V A;  4GS7 A;  1V7N V;  3UX9 A;  3HOX D;  3VA2 A;  3PIW A;  1ITL A;  1M4A A;  3DI2 A;  1HZI A;  1QVN A;  4LDS A;  5IYB D;  1FYH A;  2JA5 D;  3QB1 A;  1PGR A;  1M4R A;  4J05 A;  1ITM A;  5IP9 D;  3N06 A;  4BBR D;  4NKQ C;  3G6D A;  3H3V E;  5FUC A;  3D48 P;  2PSM A;  2GMF A;  4NI7 A;  5C7X A;  4TPJ A;  4YB9 D;  1ALU A;  3PO2 D;  3N0P A;  5D71 A;  3TGX B;  1PW6 A;  1GA3 A;  2R92 D;  2D9Q A;  5EQI A;  2R93 D;  1PV7 A;  1P9M B;  3O7P A;  1Y14 A;  4BBS D;  5IYD D;  5A2O A;  1LKI A;  5C4X D;  1EXZ A;  3AYH A;  1HUL A;  2B63 D;  2B5I A;  1ITI A;  4O9H A;  2Q7N B;  3O7Q A;  4CNI C;  3SE4 B;  2ERJ D;  4J4L C;  4DKF A;  4D2B A;  1AXI A;  2JA6 D;  2JA8 D;  3DUH C;  2O6I A;  1CD9 A;  4GBY A;  4A3B D;  3HOZ D;  3D85 C;  1Y6N L;  4LRL A;  3OG6 A;  5C44 D;  1Y6K L;  1ETE A;  4Z5R D;  4ZW9 A;  1M48 A;  4YDY I;  3L5X A;  1M49 A;  1M4B A;  1RFB A;  3MZG A;  5D6K A;  4U4W A;  1HGU A;  3NPZ A;  4DKC A;  4RS1 A;  2B90 A;  2CYK A;  4NI9 A;  2Z3Q A;  2IL6 A;  1M4C A;  1CSG A;  4X51 A;  2JA7 D;  4ZWC A;  1BCN A;  4ZWB A;  4IKW A;  5TS9 A;  1RCB A;  2OQP A;  1INR A;  4UVM A;  2CFP A;  4OH3 A;  4YQX A;  2Q98 A;  3FKI D;  5L6Y C;  4A3J D;  3I4M D;  1RHG A;  2D48 A;  4Q65 A;  3EJJ A;  1CN4 C;  2L3Y A;  4FA8 E;  2O26 A;  4NN7 A;  2R7Z D;  4WRL B;  3HMX B;  3HHR A;  4APS A;  1A22 A;  2C35 A;  2H24 A;  1F45 B;  1Z7C A;  4DKD A;  3EW3 A;  4IKV A;  5D72 A;  2Q14 A;  4IU9 A;  5D58 A;  4A3D D;  4IU8 A;  1HUW A;  4A3L D;  4D2D A;  1BP3 A;  1AX8 A;  5EQH A;  4TPH A;  4BY7 D;  1HIJ A;  1CNT 1;  5FLM D;  5IP7 D;  4GC0 A;  1V7M V;  4PS4 A;  1WU3 I;  3DI3 A;  3D87 A;  4MHL A;  4IKX A;  3UEZ E;  4ZYR A;  1LK3 A;  3BPL A;  4U4T A;  3PIV A;  3NCB A;  1A7M A;  4YUE C;  3QAZ A;  1AU1 A;  1EKU A;  4IKZ A;  4EXP A;  1YKB A;  2ILK A;  4ZS7 A;  3HOU D;  5EQG A;  4A3F D;  4PYP A;  1D9C A;  2O27 A;  3NCF A;  4A3I D;  3OQ3 A;  1BGC A;  3NCE A;  4O6K A;  3WCY I;  1WCM D;  1F6F A;  3BPO A;  5A2N A;  2CFQ A;  1BGE A;  3DGC L;  2VUM D;  4NN5 A;  5C65 A;  4A3G D;  3OG4 A;  1CYL A;  1SCF A;  4JA3 A;  1Y1V D;  4XNI A;  3HOV D;  2XUT A;  1IK0 A;  4JRE A;  4A93 D;  1IRL A;  3H0G D;  1D9G A;  1ITF A;  3SE3 B;  3NCC A;  4OAA A;  4JR9 A;  4D2C A;  4YBQ A;  1ILK A;  2L3O A;  4IKY A;  1JLI A;  3BPN A;  3UF5 A;  4BY1 D;  1HWG A;  1NBP A;  1EMR A;  4DOH A;  3LB6 B;  5LQB A;  2B8X A;  1HIK A;  2B8Z A;  3LB6 A;  2Y5Y A;  1BBN A;  4W6V A;  1EER A;  3HOY D;  4A3E D;  5E4E A;  2LAG A;  3QT2 C;  1B5L A;  1Y1W D;  4NEM A;  1HWH A;  3UF2 A;  1EVS A;  3BES L;  5D59 A;  4NEJ A;  1PVH B;  1N1F A;  2KZ1 A;  4BXX D;  3QB7 A;  1M47 A;  5D70 A;  2XQB A;  4DKE A;  1PW4 A;  5IYC D;  4EXN A;  4A3K D;  1GNC A;  2INT A;  3IRH A;  3HOW D;  3Q1S I;  2B8U A;  4XNJ A;  4GBZ A;  3S9D A;  2LMS A;  5KNH I;  1BUY A;  1Y6M L;  1BGD A;  2E9W C;  1Z92 A;  4I77 Z;  2Z3R A;  1KF9 A;  4YPG C;  2B8Y A;  3INK C;  4A3C D;  1IJZ A;  4GRW A;  5D22 A;  5C3E D;  1LQS L;  1PY2 A;  1J7V L;  3B5K A;  5D28 B;  2B91 A;  3I4N D;  2V8N A;  3HHC A;  4QIQ A;  1IAR A;  1PV6 A;  5FHX A;  3L5W I;  3WDO A;  1VLK A;  3DLQ I;  1RW5 A;  3QWR B;  4NN6 A;  4A3M D;  4LEP A;  3PO3 D;  4ZF7 A;  3G9V B;  2HYM B;  1I1R B; 
#chains in the Genus database with same CATH homology
 4OAA A;  4TPG A;  4JR9 A;  2Y5Y A;  4GC0 A;  4IKV A;  4Q65 A;  4D2C A;  4YBQ A;  3O7Q A;  4W6V A;  5GXB A;  4U4V A;  4IU9 A;  5C65 A;  4XNJ A;  4J05 A;  4GBZ A;  4IKX A;  5EQI A;  4ZWC A;  2V8N A;  4IKY A;  4ZYR A;  5D58 A;  5EQG A;  4IU8 A;  4ZWB A;  4PYP A;  1PV7 A;  4IKW A;  4QIQ A;  4JA3 A;  1PW4 A;  4ZW9 A;  4XNI A;  4D2D A;  4D2B A;  3O7P A;  1PV6 A;  3WDO A;  4UVM A;  5A2O A;  2XUT A;  2CFP A;  5D6K A;  5EQH A;  4JRE A;  4OH3 A;  4U4W A;  4U4T A;  4TPH A;  4LDS A;  4GBY A;  5A2N A;  4LEP A;  4APS A;  2CFQ A;  5D59 A;  4TPJ A;  4YB9 D;  4IKZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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