4PYPA

Crystal structure of the human glucose transporter glut1
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
447
structure length
447
Chain Sequence
TGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYTQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVQRAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human glucose transporter GLUT1
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Solute carrier family 2, facilitated glucose transporter mem
total genus 166
structure length 447
sequence length 447
ec nomenclature
pdb deposition date 2014-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4pypA00
4IKVA 4GBYA 4GC0A 4JR9A 4LEPA 4JREA 4Q65A 2CFPA 2XUTA 3WDOA 4D2DA 4ZWBA 4W6VA 5A2NA 4QIQA 4IU8A 4IKYA 4D2CA 4YB9D 1PV6A 5D59A 4LDSA 4ZWCA 5D58A 5C65A 4U4TA 4TPJA 4ZYRA 4TPGA 5D6KA 3O7PA 4UVMA 4PYPA 4IU9A 4JA3A 4TPHA 4XNIA 4IKWA 3O7QA 4U4WA 2CFQA 4J05A 2Y5YA 4OAAA 5EQHA 4D2BA 5GXBA 2V8NA 4XNJA 5EQGA 4OH3A 4IKXA 4IKZA 1PV7A 4YBQA 4GBZA 4ZW9A 5EQIA 1PW4A 4APSA 5A2OA 4U4VA
chains in the Genus database with same CATH superfamily
1F45B 3EJJA 2E9WC 5IP9D 3G6DA 4TPGA 1IK0A 2O6IA 3OG6A 4PYPA 3SE4B 5L6YC 4MHLA 1BGDA 4IKXA 4Z5RD 1EXZA 1Z7CA 5EQIA 1RW5A 1FG9A 4DKEA 2LAGA 3UX9A 5IYCD 4A3ID 5C4XD 2LMSA 4CNIC 3NPZA 4DKFA 5C65A 3LB6A 4BY1D 1EMRA 1M47A 1BP3A 4NEMA 5FHXA 2L3OA 3D87A 4OAAA 3LB6B 3PO3D 3QWRB 4BBRD 2Q98A 1ITMA 3QT2C 4JREA 2CFPA 4A3GD 5A2NA 1HULA 4IKYA 4FA8E 2VUMD 3H3VE 3AYHA 2JA7D 1A7MA 4A93D 1WU3I 3G9VB 1AXIA 4LRLA 2R7ZD 1HGUA 1PV7A 1CN4C 3I4ND 2OQPA 4BXXD 3DGCL 4D2CA 1PW6A 3IRHA 1PGRA 1PV6A 4YB9D 1ITIA 1HUWA 3L5XA 3L5WI 4YDYI 3BPOA 3HOYD 2ERJD 1VLKA 4X51A 3D48P 5IYDD 2Q14A 1D9GA 5D71A 2XUTA 5KNHI 3HOXD 5D72A 3OG4A 3UF2A 3INKC 4UVMA 2B5IA 2Y5YA 5EQHA 1I1RB 3QB1A 1V7MV 2O27A 4O9HA 1ITFA 4A3DD 2O26A 3PIWA 4A3ED 4NKQC 1BGEA 3HMXB 3HOVD 3HOZD 4EXNA 4J4LC 4U4WA 3D85C 3DLQI 4ZW9A 2JA6D 3QAZA 2B8XA 1B5LA 1RCBA 3S9DA 3HOUD 3HHRA 4ZYRA 5D6KA 4BBSD 4IU9A 5IYBD 5D22A 1FYHA 4YBQA 4GBZA 3BPNA 1IRLA 1PW4A 4LEPA 4GC0A 1BCNA 1ILKA 3NCEA 1ITLA 1NBPA 1CSGA 4O6KA 4A3KD 5D59A 1INRA 2HYMB 4TPJA 3UEZE 3MZGA 4DKDA 3O7PA 4A3LD 4NN7A 2KZ1A 4NN5A 2CFQA 4RS1A 4A3MD 4W6VA 1LKIA 2XQBA 3N0PA 2GMFA 1A22A 4IU8A 3QB7A 4NI7A 5D58A 1P9MB 4EXPA 4DOHA 5FUCA 4YPGC 1M4CA 1CYLA 4TPHA 4XNIA 2B63D 2B90A 1RFBA 3N06A 4U4VA 4GBYA 4Q65A 4DKCA 4D2DA 1AX8A 4ZF7A 2B8UA 3BESL 4A3JD 4ZS7A 1WCMD 1GNCA 2JA5D 1YKBA 5A2OA 3PIVA 4JR9A 1J7VL 1Y6NL 1F6FA 2L3YA 4LDSA 5C3ED 2IL6A 4A3BD 4A3CD 5IP7D 3TGXB 2Q7NB 3O7QA 2D48A 4J05A 4XNJA 3HOWD 5D28B 3NCBA 1D9CA 3FKID 1CNT1 1M4RA 3Q1SI 4A3FD 1LQSL 3WCYI 1Y6KL 1BGCA 3BPLA 3DI3A 1M49A 1M48A 5GXBA 1IARA 2V8NA 1EKUA 2B8ZA 3NCCA 1M4AA 1Z92A 5FLMD 1JLIA 1PY2A 3DUHC 4ZWCA 2JA8D 1N1FA 1HWHA 2Z3RA 4JA3A 4NN6A 1SCFA 1IL6A 1HWGA 1LK3A 3OQ3A 4IKZA 1EERA 1KF9A 1HZIA 1ALUA 1Y14A 5TS9A 2Z3QA 1QVNA 4GRWA 4U4TA 2CYKA 1GA3A 1CD9A 3PO2D 1PVHB 1M4BA 1Y6ML 4IKWA 4OH3A 3I4MD 4PS4A 1Y1VD 1ETEA 5D70A 4IKVA 1IJZA 2B8YA 4QIQA 3VA2A 2PSMA 1RHGA 3H0GD 5C7XA 2B91A 5LQBA 1HIKA 2ILKA 3SE3B 1Y1WD 5EQGA 2H24A 3HHCA 1EVSA 2R92D 3WDOA 3EW3A 4YQXA 4ZWBA 2R93D 3NCFA 3B5KA 4YUEC 2D9QA 4NEJA 5E4EA 1V7NV 4I77Z 5C44D 4D2BA 1BUYA 2INTA 1HIJA 3DI2A 4GS7A 4WRLB 4BY7D 2C35A 1AU1A 4APSA 4NI9A 1BBNA 3UF5A
chains in the Genus database with same CATH topology
4IKVA 4GBYA 4GC0A 4JR9A 4LEPA 4JREA 4Q65A 2CFPA 2XUTA 3WDOA 4D2DA 4ZWBA 4W6VA 5A2NA 4QIQA 4IU8A 4IKYA 4D2CA 4YB9D 1PV6A 5D59A 4LDSA 4ZWCA 5D58A 5C65A 4U4TA 4TPJA 4ZYRA 4TPGA 5D6KA 3O7PA 4UVMA 4PYPA 4IU9A 4JA3A 4TPHA 4XNIA 4IKWA 3O7QA 4U4WA 2CFQA 4J05A 2Y5YA 4OAAA 5EQHA 4D2BA 5GXBA 2V8NA 4XNJA 5EQGA 4OH3A 4IKXA 4IKZA 1PV7A 4YBQA 4GBZA 4ZW9A 5EQIA 1PW4A 4APSA 5A2OA 4U4VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKV A;  4GBY A;  4GC0 A;  4JR9 A;  4LEP A;  4JRE A;  4Q65 A;  2CFP A;  2XUT A;  3WDO A;  4D2D A;  4ZWB A;  4W6V A;  5A2N A;  4QIQ A;  4IU8 A;  4IKY A;  4D2C A;  4YB9 D;  1PV6 A;  5D59 A;  4LDS A;  4ZWC A;  5D58 A;  5C65 A;  4U4T A;  4TPJ A;  4ZYR A;  4TPG A;  5D6K A;  3O7P A;  4UVM A;  4PYP A;  4IU9 A;  4JA3 A;  4TPH A;  4XNI A;  4IKW A;  3O7Q A;  4U4W A;  2CFQ A;  4J05 A;  2Y5Y A;  4OAA A;  5EQH A;  4D2B A;  5GXB A;  2V8N A;  4XNJ A;  5EQG A;  4OH3 A;  4IKX A;  4IKZ A;  1PV7 A;  4YBQ A;  4GBZ A;  4ZW9 A;  5EQI A;  1PW4 A;  4APS A;  5A2O A;  4U4V A; 
#chains in the Genus database with same CATH topology
 1F45 B;  3EJJ A;  2E9W C;  5IP9 D;  3G6D A;  4TPG A;  1IK0 A;  2O6I A;  3OG6 A;  4PYP A;  3SE4 B;  5L6Y C;  4MHL A;  1BGD A;  4IKX A;  4Z5R D;  1EXZ A;  1Z7C A;  5EQI A;  1RW5 A;  1FG9 A;  4DKE A;  2LAG A;  3UX9 A;  5IYC D;  4A3I D;  5C4X D;  2LMS A;  4CNI C;  3NPZ A;  4DKF A;  5C65 A;  3LB6 A;  4BY1 D;  1EMR A;  1M47 A;  1BP3 A;  4NEM A;  5FHX A;  2L3O A;  3D87 A;  4OAA A;  3LB6 B;  3PO3 D;  3QWR B;  4BBR D;  2Q98 A;  1ITM A;  3QT2 C;  4JRE A;  2CFP A;  4A3G D;  5A2N A;  1HUL A;  4IKY A;  4FA8 E;  2VUM D;  3H3V E;  3AYH A;  2JA7 D;  1A7M A;  4A93 D;  1WU3 I;  3G9V B;  1AXI A;  4LRL A;  2R7Z D;  1HGU A;  1PV7 A;  1CN4 C;  3I4N D;  2OQP A;  4BXX D;  3DGC L;  4D2C A;  1PW6 A;  3IRH A;  1PGR A;  1PV6 A;  4YB9 D;  1ITI A;  1HUW A;  3L5X A;  3L5W I;  4YDY I;  3BPO A;  3HOY D;  2ERJ D;  1VLK A;  4X51 A;  3D48 P;  5IYD D;  2Q14 A;  1D9G A;  5D71 A;  2XUT A;  5KNH I;  3HOX D;  5D72 A;  3OG4 A;  3UF2 A;  3INK C;  4UVM A;  2B5I A;  2Y5Y A;  5EQH A;  1I1R B;  3QB1 A;  1V7M V;  2O27 A;  4O9H A;  1ITF A;  4A3D D;  2O26 A;  3PIW A;  4A3E D;  4NKQ C;  1BGE A;  3HMX B;  3HOV D;  3HOZ D;  4EXN A;  4J4L C;  4U4W A;  3D85 C;  3DLQ I;  4ZW9 A;  2JA6 D;  3QAZ A;  2B8X A;  1B5L A;  1RCB A;  3S9D A;  3HOU D;  3HHR A;  4ZYR A;  5D6K A;  4BBS D;  4IU9 A;  5IYB D;  5D22 A;  1FYH A;  4YBQ A;  4GBZ A;  3BPN A;  1IRL A;  1PW4 A;  4LEP A;  4GC0 A;  1BCN A;  1ILK A;  3NCE A;  1ITL A;  1NBP A;  1CSG A;  4O6K A;  4A3K D;  5D59 A;  1INR A;  2HYM B;  4TPJ A;  3UEZ E;  3MZG A;  4DKD A;  3O7P A;  4A3L D;  4NN7 A;  2KZ1 A;  4NN5 A;  2CFQ A;  4RS1 A;  4A3M D;  4W6V A;  1LKI A;  2XQB A;  3N0P A;  2GMF A;  1A22 A;  4IU8 A;  3QB7 A;  4NI7 A;  5D58 A;  1P9M B;  4EXP A;  4DOH A;  5FUC A;  4YPG C;  1M4C A;  1CYL A;  4TPH A;  4XNI A;  2B63 D;  2B90 A;  1RFB A;  3N06 A;  4U4V A;  4GBY A;  4Q65 A;  4DKC A;  4D2D A;  1AX8 A;  4ZF7 A;  2B8U A;  3BES L;  4A3J D;  4ZS7 A;  1WCM D;  1GNC A;  2JA5 D;  1YKB A;  5A2O A;  3PIV A;  4JR9 A;  1J7V L;  1Y6N L;  1F6F A;  2L3Y A;  4LDS A;  5C3E D;  2IL6 A;  4A3B D;  4A3C D;  5IP7 D;  3TGX B;  2Q7N B;  3O7Q A;  2D48 A;  4J05 A;  4XNJ A;  3HOW D;  5D28 B;  3NCB A;  1D9C A;  3FKI D;  1CNT 1;  1M4R A;  3Q1S I;  4A3F D;  1LQS L;  3WCY I;  1Y6K L;  1BGC A;  3BPL A;  3DI3 A;  1M49 A;  1M48 A;  5GXB A;  1IAR A;  2V8N A;  1EKU A;  2B8Z A;  3NCC A;  1M4A A;  1Z92 A;  5FLM D;  1JLI A;  1PY2 A;  3DUH C;  4ZWC A;  2JA8 D;  1N1F A;  1HWH A;  2Z3R A;  4JA3 A;  4NN6 A;  1SCF A;  1IL6 A;  1HWG A;  1LK3 A;  3OQ3 A;  4IKZ A;  1EER A;  1KF9 A;  1HZI A;  1ALU A;  1Y14 A;  5TS9 A;  2Z3Q A;  1QVN A;  4GRW A;  4U4T A;  2CYK A;  1GA3 A;  1CD9 A;  3PO2 D;  1PVH B;  1M4B A;  1Y6M L;  4IKW A;  4OH3 A;  3I4M D;  4PS4 A;  1Y1V D;  1ETE A;  5D70 A;  4IKV A;  1IJZ A;  2B8Y A;  4QIQ A;  3VA2 A;  2PSM A;  1RHG A;  3H0G D;  5C7X A;  2B91 A;  5LQB A;  1HIK A;  2ILK A;  3SE3 B;  1Y1W D;  5EQG A;  2H24 A;  3HHC A;  1EVS A;  2R92 D;  3WDO A;  3EW3 A;  4YQX A;  4ZWB A;  2R93 D;  3NCF A;  3B5K A;  4YUE C;  2D9Q A;  4NEJ A;  5E4E A;  1V7N V;  4I77 Z;  5C44 D;  4D2B A;  1BUY A;  2INT A;  1HIJ A;  3DI2 A;  4GS7 A;  4WRL B;  4BY7 D;  2C35 A;  1AU1 A;  4APS A;  4NI9 A;  1BBN A;  3UF5 A; 
#chains in the Genus database with same CATH homology
 4IKV A;  4GBY A;  4GC0 A;  4JR9 A;  4LEP A;  4JRE A;  4Q65 A;  2CFP A;  2XUT A;  3WDO A;  4D2D A;  4ZWB A;  4W6V A;  5A2N A;  4QIQ A;  4IU8 A;  4IKY A;  4D2C A;  4YB9 D;  1PV6 A;  5D59 A;  4LDS A;  4ZWC A;  5D58 A;  5C65 A;  4U4T A;  4TPJ A;  4ZYR A;  4TPG A;  5D6K A;  3O7P A;  4UVM A;  4PYP A;  4IU9 A;  4JA3 A;  4TPH A;  4XNI A;  4IKW A;  3O7Q A;  4U4W A;  2CFQ A;  4J05 A;  2Y5Y A;  4OAA A;  5EQH A;  4D2B A;  5GXB A;  2V8N A;  4XNJ A;  5EQG A;  4OH3 A;  4IKX A;  4IKZ A;  1PV7 A;  4YBQ A;  4GBZ A;  4ZW9 A;  5EQI A;  1PW4 A;  4APS A;  5A2O A;  4U4V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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