4QIQA

Crystal structure of d-xylose-proton symporter
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
464
structure length
439
Chain Sequence
SYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMTLATQAVQEIKHSLDRLLMFGVGVIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKGKTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords D-xylose-proton symporter
total genus 144
structure length 439
sequence length 464
ec nomenclature
pdb deposition date 2014-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4qiqA00
5A2OA 2V8NA 2Y5YA 4LEPA 4TPJA 4ZWBA 4YB9D 2CFQA 4ZW9A 4XNIA 4IKZA 4ZYRA 1PV6A 5GXBA 4IKVA 4IKWA 5A2NA 4OH3A 4IKXA 4IKYA 4GC0A 4TPGA 2CFPA 1PV7A 5D6KA 4YBQA 4D2DA 4U4WA 4IU8A 4J05A 4PYPA 4D2CA 4OAAA 5EQGA 4APSA 4W6VA 4XNJA 4U4TA 4UVMA 4Q65A 4IU9A 5C65A 2XUTA 3O7PA 4GBYA 5D59A 4JA3A 4U4VA 4JR9A 4D2BA 5EQHA 3WDOA 4ZWCA 4QIQA 3O7QA 4GBZA 5D58A 5EQIA 4TPHA 4JREA 1PW4A 4LDSA
chains in the Genus database with same CATH superfamily
2V8NA 4LEPA 4ZYRA 2Q7NB 5GXBA 5TS9A 3N0PA 3NPZA 1VLKA 4GC0A 4NI7A 1FYHA 1ILKA 4XNJA 3UF2A 5D59A 5IP9D 2B8UA 1BBNA 1RCBA 4GBZA 3H0GD 1A7MA 1A22A 2HYMB 1GA3A 3PO2D 3DLQI 3Q1SI 4IKXA 4A3FD 3UX9A 4O9HA 2ERJD 5IYCD 4IU8A 5EQGA 1EXZA 4BY7D 2JA8D 3PO3D 2L3OA 2JA5D 3QWRB 4JREA 5A2OA 1BP3A 1KF9A 1YKBA 1PY2A 4A3CD 3EW3A 4A3BD 2B90A 1CN4C 4BY1D 4TPGA 4J05A 1PW6A 1P9MB 2B5IA 1B5LA 5C3ED 4NEMA 1BGCA 1Y6ML 2R7ZD 4QIQA 3HHRA 2PSMA 5IP7D 4TPJA 1F45B 1D9GA 4IKYA 1HIKA 4YBQA 4D2CA 1CSGA 4A3LD 3D48P 1RW5A 1CNT1 2OQPA 1Y6KL 1EKUA 3HOUD 4DKFA 2KZ1A 3INKC 4ZWBA 4YB9D 1BUYA 4IKWA 2IL6A 5FUCA 1IJZA 4ZS7A 5C4XD 3D87A 3UEZE 1HZIA 3QAZA 5FLMD 4DKEA 3BESL 1EMRA 5EQIA 1RHGA 4TPHA 1M48A 1Y1VD 4YPGC 2B91A 5KNHI 5L6YC 4ZW9A 3VA2A 4GRWA 1EVSA 3G9VB 3QB1A 2R93D 1ITMA 3LB6A 1PVHB 4Q65A 1HWGA 1HIJA 3SE3B 4U4VA 1SCFA 1N1FA 4GS7A 2JA6D 4DKDA 5C7XA 2Q14A 3O7QA 1LKIA 3NCFA 2D9QA 3HOZD 1ITFA 3NCCA 2CFQA 1HGUA 5E4EA 5A2NA 3DI3A 3DUHC 1D9CA 2LAGA 4A3ID 3EJJA 1ALUA 4NI9A 3O7PA 2Z3RA 3LB6B 1QVNA 4JA3A 1HUWA 3HHCA 4FA8E 4ZWCA 4DOHA 4LRLA 2INTA 1FG9A 2Q98A 1M49A 1IL6A 4IKZA 3HOVD 4I77Z 3PIVA 4NN5A 3L5XA 4IU9A 2XUTA 4Z5RD 1CYLA 4NEJA 4NN6A 1CD9A 4CNIC 4MHLA 3BPLA 4U4WA 4PS4A 4PYPA 4EXNA 5D70A 1LQSL 4YQXA 1M4RA 2VUMD 1V7NV 1PV6A 4IKVA 2ILKA 3TGXB 3N06A 4OAAA 4APSA 3AYHA 2L3YA 2B8XA 1IARA 3B5KA 1M4AA 5D71A 3MZGA 1AU1A 1Z7CA 3DGCL 2O27A 1EERA 4A93D 1NBPA 2O26A 4A3KD 1Y14A 1BCNA 2CFPA 1PV7A 5D6KA 4EXPA 5FHXA 2Z3QA 4U4TA 5C65A 4J4LC 1WU3I 3PIWA 5D58A 4BBSD 1HULA 2XQBA 4LDSA 1WCMD 3S9DA 1M4BA 1AXIA 3WCYI 1ITIA 1INRA 5IYDD 3I4MD 3NCEA 1PGRA 3BPOA 3G6DA 4UVMA 3I4ND 1IK0A 3QT2C 2O6IA 1AX8A 5IYBD 3HOWD 2B63D 4XNIA 4YUEC 3OG4A 4O6KA 4DKCA 5D22A 1I1RB 2GMFA 1GNCA 3HOYD 3UF5A 4A3JD 1RFBA 2CYKA 1M4CA 3DI2A 4D2BA 1ITLA 1Y1WD 1JLIA 3OQ3A 2Y5YA 2B8YA 4NN7A 5LQBA 2R92D 3OG6A 3L5WI 4A3MD 1IRLA 3D85C 4RS1A 4GBYA 3FKID 2C35A 3H3VE 4JR9A 4X51A 3HMXB 2JA7D 5EQHA 3WDOA 3HOXD 1J7VL 1Y6NL 2D48A 3SE4B 1LK3A 4OH3A 2B8ZA 4YDYI 4D2DA 3QB7A 4WRLB 1BGEA 4A3DD 1BGDA 1HWHA 1M47A 4BBRD 5D72A 1Z92A 2E9WC 4A3GD 4W6VA 2LMSA 3NCBA 3BPNA 5C44D 4NKQC 3IRHA 4A3ED 1ETEA 4BXXD 2H24A 4ZF7A 1V7MV 1F6FA 5D28B 1PW4A
chains in the Genus database with same CATH topology
5A2OA 2V8NA 2Y5YA 4LEPA 4TPJA 4ZWBA 4YB9D 2CFQA 4ZW9A 4XNIA 4IKZA 4ZYRA 1PV6A 5GXBA 4IKVA 4IKWA 5A2NA 4OH3A 4IKXA 4IKYA 4GC0A 4TPGA 2CFPA 1PV7A 5D6KA 4YBQA 4D2DA 4U4WA 4IU8A 4J05A 4PYPA 4D2CA 4OAAA 5EQGA 4APSA 4W6VA 4XNJA 4U4TA 4UVMA 4Q65A 4IU9A 5C65A 2XUTA 3O7PA 4GBYA 5D59A 4JA3A 4U4VA 4JR9A 4D2BA 5EQHA 3WDOA 4ZWCA 4QIQA 3O7QA 4GBZA 5D58A 5EQIA 4TPHA 4JREA 1PW4A 4LDSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A2O A;  2V8N A;  2Y5Y A;  4LEP A;  4TPJ A;  4ZWB A;  4YB9 D;  2CFQ A;  4ZW9 A;  4XNI A;  4IKZ A;  4ZYR A;  1PV6 A;  5GXB A;  4IKV A;  4IKW A;  5A2N A;  4OH3 A;  4IKX A;  4IKY A;  4GC0 A;  4TPG A;  2CFP A;  1PV7 A;  5D6K A;  4YBQ A;  4D2D A;  4U4W A;  4IU8 A;  4J05 A;  4PYP A;  4D2C A;  4OAA A;  5EQG A;  4APS A;  4W6V A;  4XNJ A;  4U4T A;  4UVM A;  4Q65 A;  4IU9 A;  5C65 A;  2XUT A;  3O7P A;  4GBY A;  5D59 A;  4JA3 A;  4U4V A;  4JR9 A;  4D2B A;  5EQH A;  3WDO A;  4ZWC A;  4QIQ A;  3O7Q A;  4GBZ A;  5D58 A;  5EQI A;  4TPH A;  4JRE A;  1PW4 A;  4LDS A; 
#chains in the Genus database with same CATH topology
 2V8N A;  4LEP A;  4ZYR A;  2Q7N B;  5GXB A;  5TS9 A;  3N0P A;  3NPZ A;  1VLK A;  4GC0 A;  4NI7 A;  1FYH A;  1ILK A;  4XNJ A;  3UF2 A;  5D59 A;  5IP9 D;  2B8U A;  1BBN A;  1RCB A;  4GBZ A;  3H0G D;  1A7M A;  1A22 A;  2HYM B;  1GA3 A;  3PO2 D;  3DLQ I;  3Q1S I;  4IKX A;  4A3F D;  3UX9 A;  4O9H A;  2ERJ D;  5IYC D;  4IU8 A;  5EQG A;  1EXZ A;  4BY7 D;  2JA8 D;  3PO3 D;  2L3O A;  2JA5 D;  3QWR B;  4JRE A;  5A2O A;  1BP3 A;  1KF9 A;  1YKB A;  1PY2 A;  4A3C D;  3EW3 A;  4A3B D;  2B90 A;  1CN4 C;  4BY1 D;  4TPG A;  4J05 A;  1PW6 A;  1P9M B;  2B5I A;  1B5L A;  5C3E D;  4NEM A;  1BGC A;  1Y6M L;  2R7Z D;  4QIQ A;  3HHR A;  2PSM A;  5IP7 D;  4TPJ A;  1F45 B;  1D9G A;  4IKY A;  1HIK A;  4YBQ A;  4D2C A;  1CSG A;  4A3L D;  3D48 P;  1RW5 A;  1CNT 1;  2OQP A;  1Y6K L;  1EKU A;  3HOU D;  4DKF A;  2KZ1 A;  3INK C;  4ZWB A;  4YB9 D;  1BUY A;  4IKW A;  2IL6 A;  5FUC A;  1IJZ A;  4ZS7 A;  5C4X D;  3D87 A;  3UEZ E;  1HZI A;  3QAZ A;  5FLM D;  4DKE A;  3BES L;  1EMR A;  5EQI A;  1RHG A;  4TPH A;  1M48 A;  1Y1V D;  4YPG C;  2B91 A;  5KNH I;  5L6Y C;  4ZW9 A;  3VA2 A;  4GRW A;  1EVS A;  3G9V B;  3QB1 A;  2R93 D;  1ITM A;  3LB6 A;  1PVH B;  4Q65 A;  1HWG A;  1HIJ A;  3SE3 B;  4U4V A;  1SCF A;  1N1F A;  4GS7 A;  2JA6 D;  4DKD A;  5C7X A;  2Q14 A;  3O7Q A;  1LKI A;  3NCF A;  2D9Q A;  3HOZ D;  1ITF A;  3NCC A;  2CFQ A;  1HGU A;  5E4E A;  5A2N A;  3DI3 A;  3DUH C;  1D9C A;  2LAG A;  4A3I D;  3EJJ A;  1ALU A;  4NI9 A;  3O7P A;  2Z3R A;  3LB6 B;  1QVN A;  4JA3 A;  1HUW A;  3HHC A;  4FA8 E;  4ZWC A;  4DOH A;  4LRL A;  2INT A;  1FG9 A;  2Q98 A;  1M49 A;  1IL6 A;  4IKZ A;  3HOV D;  4I77 Z;  3PIV A;  4NN5 A;  3L5X A;  4IU9 A;  2XUT A;  4Z5R D;  1CYL A;  4NEJ A;  4NN6 A;  1CD9 A;  4CNI C;  4MHL A;  3BPL A;  4U4W A;  4PS4 A;  4PYP A;  4EXN A;  5D70 A;  1LQS L;  4YQX A;  1M4R A;  2VUM D;  1V7N V;  1PV6 A;  4IKV A;  2ILK A;  3TGX B;  3N06 A;  4OAA A;  4APS A;  3AYH A;  2L3Y A;  2B8X A;  1IAR A;  3B5K A;  1M4A A;  5D71 A;  3MZG A;  1AU1 A;  1Z7C A;  3DGC L;  2O27 A;  1EER A;  4A93 D;  1NBP A;  2O26 A;  4A3K D;  1Y14 A;  1BCN A;  2CFP A;  1PV7 A;  5D6K A;  4EXP A;  5FHX A;  2Z3Q A;  4U4T A;  5C65 A;  4J4L C;  1WU3 I;  3PIW A;  5D58 A;  4BBS D;  1HUL A;  2XQB A;  4LDS A;  1WCM D;  3S9D A;  1M4B A;  1AXI A;  3WCY I;  1ITI A;  1INR A;  5IYD D;  3I4M D;  3NCE A;  1PGR A;  3BPO A;  3G6D A;  4UVM A;  3I4N D;  1IK0 A;  3QT2 C;  2O6I A;  1AX8 A;  5IYB D;  3HOW D;  2B63 D;  4XNI A;  4YUE C;  3OG4 A;  4O6K A;  4DKC A;  5D22 A;  1I1R B;  2GMF A;  1GNC A;  3HOY D;  3UF5 A;  4A3J D;  1RFB A;  2CYK A;  1M4C A;  3DI2 A;  4D2B A;  1ITL A;  1Y1W D;  1JLI A;  3OQ3 A;  2Y5Y A;  2B8Y A;  4NN7 A;  5LQB A;  2R92 D;  3OG6 A;  3L5W I;  4A3M D;  1IRL A;  3D85 C;  4RS1 A;  4GBY A;  3FKI D;  2C35 A;  3H3V E;  4JR9 A;  4X51 A;  3HMX B;  2JA7 D;  5EQH A;  3WDO A;  3HOX D;  1J7V L;  1Y6N L;  2D48 A;  3SE4 B;  1LK3 A;  4OH3 A;  2B8Z A;  4YDY I;  4D2D A;  3QB7 A;  4WRL B;  1BGE A;  4A3D D;  1BGD A;  1HWH A;  1M47 A;  4BBR D;  5D72 A;  1Z92 A;  2E9W C;  4A3G D;  4W6V A;  2LMS A;  3NCB A;  3BPN A;  5C44 D;  4NKQ C;  3IRH A;  4A3E D;  1ETE A;  4BXX D;  2H24 A;  4ZF7 A;  1V7M V;  1F6F A;  5D28 B;  1PW4 A; 
#chains in the Genus database with same CATH homology
 5A2O A;  2V8N A;  2Y5Y A;  4LEP A;  4TPJ A;  4ZWB A;  4YB9 D;  2CFQ A;  4ZW9 A;  4XNI A;  4IKZ A;  4ZYR A;  1PV6 A;  5GXB A;  4IKV A;  4IKW A;  5A2N A;  4OH3 A;  4IKX A;  4IKY A;  4GC0 A;  4TPG A;  2CFP A;  1PV7 A;  5D6K A;  4YBQ A;  4D2D A;  4U4W A;  4IU8 A;  4J05 A;  4PYP A;  4D2C A;  4OAA A;  5EQG A;  4APS A;  4W6V A;  4XNJ A;  4U4T A;  4UVM A;  4Q65 A;  4IU9 A;  5C65 A;  2XUT A;  3O7P A;  4GBY A;  5D59 A;  4JA3 A;  4U4V A;  4JR9 A;  4D2B A;  5EQH A;  3WDO A;  4ZWC A;  4QIQ A;  3O7Q A;  4GBZ A;  5D58 A;  5EQI A;  4TPH A;  4JRE A;  1PW4 A;  4LDS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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