4U4TA

Structure of a nitrate/nitrite antiporter nark in nitrate-bound inward-open state
Total Genus 185
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
185
sequence length
451
structure length
444
Chain Sequence
VITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGRRWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWIWVPFLAIFTIAAWFGMNDLATQLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGLLFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSDERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACVVITWAVYGRHSKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Escherichia coli str. k12 substr. mg1655
publication title Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
pubmed doi rcsb
molecule keywords Nitrate/nitrite transporter NarK
total genus 185
structure length 444
sequence length 451
ec nomenclature
pdb deposition date 2014-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4tA01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4tA02
4GC0A 4U4TA 4ZYRA 4TPGA 4PYPA 5A2OA 4GBZA 4YB9D 5EQIA 4XNJA 4W6VA 3WDOA 2Y5YA 4IKVA 4TPJA 4JA3A 4IU9A 4YBQA 4U4VA 5D59A 2XUTA 4D2DA 5GXBA 2CFPA 4IKZA 4IKYA 4LEPA 4LDSA 2CFQA 4U4WA 4Q65A 4D2CA 5D58A 5C65A 4TPHA 4XNIA 5D6KA 4D2BA 4J05A 4JR9A 4JREA 1PW4A 3O7PA 1PV6A 4IKXA 4QIQA 5A2NA 4GBYA 4UVMA 4ZWBA 4IU8A 2V8NA 4OH3A 4IKWA 5EQGA 4OAAA 5EQHA 4ZW9A 3O7QA 4ZWCA 4APSA 1PV7A
chains in the Genus database with same CATH superfamily
1BGDA 3UF2A 3PIWA 1JLIA 1IL6A 5D71A 4IKVA 2L3OA 4A3JD 4YBQA 1IRLA 1WCMD 3NCEA 3SE4B 3G6DA 2CFQA 2CYKA 4A3CD 1EMRA 1M49A 5L6YC 4OH3A 1BGCA 5FHXA 1RW5A 4XNJA 1EERA 3I4ND 2B8XA 1BBNA 4XNIA 3HOWD 3HMXB 4YDYI 3O7PA 1PV6A 1F45B 4UVMA 3I4MD 1J7VL 2C35A 1Y6KL 4U4TA 1LQSL 1EKUA 3UX9A 4MHLA 1HWHA 3NCFA 3WDOA 4I77Z 1ITFA 1Y1VD 4DKFA 1AU1A 2JA8D 2E9WC 4NI7A 3DGCL 3OG4A 1WU3I 1M4RA 1CSGA 2KZ1A 1M4BA 4BXXD 4NI9A 2PSMA 1PVHB 3UF5A 4IU9A 4U4VA 3B5KA 1M4AA 4EXPA 4A3MD 3NPZA 5C7XA 1PGRA 4U4WA 1M47A 3N06A 4O6KA 5D6KA 3BPOA 4ZS7A 4BBRD 4QIQA 5A2NA 4ZF7A 5TS9A 2IL6A 4Z5RD 2R93D 4W6VA 2Y5YA 1P9MB 5D59A 4NN5A 4IKYA 4LDSA 4RS1A 3FKID 3BPLA 1INRA 1D9CA 2Q98A 3HHRA 4A3LD 2B91A 1AXIA 5EQGA 2Z3QA 2INTA 3O7QA 4NN6A 1KF9A 1BP3A 3QT2C 4YQXA 5D22A 4DKEA 4A3ID 3D48P 4LEPA 2D9QA 5D58A 1V7MV 3BESL 1F6FA 1FYHA 4NEMA 3H0GD 4A3BD 4IKWA 3D85C 5C4XD 1PV7A 2R92D 1Y1WD 3MZGA 1EXZA 2Z3RA 3IRHA 3DI2A 3INKC 4Q65A 4A3ED 1A7MA 2ILKA 3BPNA 4ZYRA 3VA2A 1IARA 2HYMB 2B8YA 5E4EA 4D2DA 3SE3B 3OG6A 2O27A 1CN4C 1HULA 3LB6B 1ITIA 3QWRB 5C65A 2VUMD 2H24A 3D87A 2D48A 4ZWCA 4APSA 3HHCA 1VLKA 1BGEA 1CNT1 4PYPA 5A2OA 4X51A 2B63D 3S9DA 3QB1A 5IP7D 1Z92A 4A3FD 3PO3D 1RHGA 3UEZE 4A3KD 5D72A 1V7NV 5C44D 1SCFA 5IYDD 4ZWBA 3DLQI 4GRWA 1BCNA 4ZW9A 1CD9A 3HOZD 1AX8A 1IJZA 5IYCD 1IK0A 1ILKA 3EW3A 2O26A 4IKZA 2LMSA 3QAZA 4D2CA 2ERJD 4EXNA 4JR9A 2B5IA 4NEJA 4IKXA 1HIJA 1HGUA 4CNIC 4GC0A 3L5WI 4GBZA 4TPJA 2B90A 2XUTA 4BBSD 3PIVA 3WCYI 3OQ3A 3NCBA 2L3YA 5IYBD 1GA3A 4NKQC 3LB6A 4D2BA 1PW4A 1RFBA 3HOUD 1LKIA 5C3ED 1I1RB 4DKDA 3N0PA 5D28B 1M48A 1ITMA 4YPGC 2GMFA 2O6IA 2CFPA 3NCCA 5KNHI 4FA8E 1ETEA 3HOYD 1FG9A 1QVNA 1HWGA 2B8UA 4NN7A 3G9VB 3AYHA 4PS4A 5EQHA 2XQBA 3DI3A 1HIKA 3L5XA 1PY2A 4A3GD 5LQBA 5FLMD 2JA7D 4WRLB 1N1FA 1HZIA 4GS7A 4BY1D 1B5LA 1LK3A 1RCBA 4OAAA 1PW6A 1BUYA 1D9GA 1CYLA 5IP9D 1EVSA 3HOVD 4YB9D 1Y14A 2OQPA 5FUCA 1Y6NL 2LAGA 2JA5D 1Y6ML 1ALUA 4GBYA 4YUEC 1GNCA 3Q1SI 2JA6D 2Q7NB 5D70A 3HOXD 4LRLA 4DKCA 1YKBA 1Z7CA 3PO2D 3DUHC 1HUWA 3QB7A 4J05A 4JREA 3H3VE 2V8NA 4DOHA 4TPGA 3TGXB 5EQIA 1A22A 4BY7D 4A93D 2B8ZA 5GXBA 4J4LC 1ITLA 4TPHA 1M4CA 1NBPA 4O9HA 4IU8A 4A3DD 2Q14A 4JA3A 3EJJA 2R7ZD
chains in the Genus database with same CATH topology
4GC0A 4U4TA 4ZYRA 4TPGA 4PYPA 5A2OA 4GBZA 4YB9D 5EQIA 4XNJA 4W6VA 3WDOA 2Y5YA 4IKVA 4TPJA 4JA3A 4IU9A 4YBQA 4U4VA 5D59A 2XUTA 4D2DA 5GXBA 2CFPA 4IKZA 4IKYA 4LEPA 4LDSA 2CFQA 4U4WA 4Q65A 4D2CA 5D58A 5C65A 4TPHA 4XNIA 5D6KA 4D2BA 4J05A 4JR9A 4JREA 1PW4A 3O7PA 1PV6A 4IKXA 4QIQA 5A2NA 4GBYA 4UVMA 4ZWBA 4IU8A 2V8NA 4OH3A 4IKWA 5EQGA 4OAAA 5EQHA 4ZW9A 3O7QA 4ZWCA 4APSA 1PV7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GC0 A;  4U4T A;  4ZYR A;  4TPG A;  4PYP A;  5A2O A;  4GBZ A;  4YB9 D;  5EQI A;  4XNJ A;  4W6V A;  3WDO A;  2Y5Y A;  4IKV A;  4TPJ A;  4JA3 A;  4IU9 A;  4YBQ A;  4U4V A;  5D59 A;  2XUT A;  4D2D A;  5GXB A;  2CFP A;  4IKZ A;  4IKY A;  4LEP A;  4LDS A;  2CFQ A;  4U4W A;  4Q65 A;  4D2C A;  5D58 A;  5C65 A;  4TPH A;  4XNI A;  5D6K A;  4D2B A;  4J05 A;  4JR9 A;  4JRE A;  1PW4 A;  3O7P A;  1PV6 A;  4IKX A;  4QIQ A;  5A2N A;  4GBY A;  4UVM A;  4ZWB A;  4IU8 A;  2V8N A;  4OH3 A;  4IKW A;  5EQG A;  4OAA A;  5EQH A;  4ZW9 A;  3O7Q A;  4ZWC A;  4APS A;  1PV7 A; 
#chains in the Genus database with same CATH topology
 1BGD A;  3UF2 A;  3PIW A;  1JLI A;  1IL6 A;  5D71 A;  4IKV A;  2L3O A;  4A3J D;  4YBQ A;  1IRL A;  1WCM D;  3NCE A;  3SE4 B;  3G6D A;  2CFQ A;  2CYK A;  4A3C D;  1EMR A;  1M49 A;  5L6Y C;  4OH3 A;  1BGC A;  5FHX A;  1RW5 A;  4XNJ A;  1EER A;  3I4N D;  2B8X A;  1BBN A;  4XNI A;  3HOW D;  3HMX B;  4YDY I;  3O7P A;  1PV6 A;  1F45 B;  4UVM A;  3I4M D;  1J7V L;  2C35 A;  1Y6K L;  4U4T A;  1LQS L;  1EKU A;  3UX9 A;  4MHL A;  1HWH A;  3NCF A;  3WDO A;  4I77 Z;  1ITF A;  1Y1V D;  4DKF A;  1AU1 A;  2JA8 D;  2E9W C;  4NI7 A;  3DGC L;  3OG4 A;  1WU3 I;  1M4R A;  1CSG A;  2KZ1 A;  1M4B A;  4BXX D;  4NI9 A;  2PSM A;  1PVH B;  3UF5 A;  4IU9 A;  4U4V A;  3B5K A;  1M4A A;  4EXP A;  4A3M D;  3NPZ A;  5C7X A;  1PGR A;  4U4W A;  1M47 A;  3N06 A;  4O6K A;  5D6K A;  3BPO A;  4ZS7 A;  4BBR D;  4QIQ A;  5A2N A;  4ZF7 A;  5TS9 A;  2IL6 A;  4Z5R D;  2R93 D;  4W6V A;  2Y5Y A;  1P9M B;  5D59 A;  4NN5 A;  4IKY A;  4LDS A;  4RS1 A;  3FKI D;  3BPL A;  1INR A;  1D9C A;  2Q98 A;  3HHR A;  4A3L D;  2B91 A;  1AXI A;  5EQG A;  2Z3Q A;  2INT A;  3O7Q A;  4NN6 A;  1KF9 A;  1BP3 A;  3QT2 C;  4YQX A;  5D22 A;  4DKE A;  4A3I D;  3D48 P;  4LEP A;  2D9Q A;  5D58 A;  1V7M V;  3BES L;  1F6F A;  1FYH A;  4NEM A;  3H0G D;  4A3B D;  4IKW A;  3D85 C;  5C4X D;  1PV7 A;  2R92 D;  1Y1W D;  3MZG A;  1EXZ A;  2Z3R A;  3IRH A;  3DI2 A;  3INK C;  4Q65 A;  4A3E D;  1A7M A;  2ILK A;  3BPN A;  4ZYR A;  3VA2 A;  1IAR A;  2HYM B;  2B8Y A;  5E4E A;  4D2D A;  3SE3 B;  3OG6 A;  2O27 A;  1CN4 C;  1HUL A;  3LB6 B;  1ITI A;  3QWR B;  5C65 A;  2VUM D;  2H24 A;  3D87 A;  2D48 A;  4ZWC A;  4APS A;  3HHC A;  1VLK A;  1BGE A;  1CNT 1;  4PYP A;  5A2O A;  4X51 A;  2B63 D;  3S9D A;  3QB1 A;  5IP7 D;  1Z92 A;  4A3F D;  3PO3 D;  1RHG A;  3UEZ E;  4A3K D;  5D72 A;  1V7N V;  5C44 D;  1SCF A;  5IYD D;  4ZWB A;  3DLQ I;  4GRW A;  1BCN A;  4ZW9 A;  1CD9 A;  3HOZ D;  1AX8 A;  1IJZ A;  5IYC D;  1IK0 A;  1ILK A;  3EW3 A;  2O26 A;  4IKZ A;  2LMS A;  3QAZ A;  4D2C A;  2ERJ D;  4EXN A;  4JR9 A;  2B5I A;  4NEJ A;  4IKX A;  1HIJ A;  1HGU A;  4CNI C;  4GC0 A;  3L5W I;  4GBZ A;  4TPJ A;  2B90 A;  2XUT A;  4BBS D;  3PIV A;  3WCY I;  3OQ3 A;  3NCB A;  2L3Y A;  5IYB D;  1GA3 A;  4NKQ C;  3LB6 A;  4D2B A;  1PW4 A;  1RFB A;  3HOU D;  1LKI A;  5C3E D;  1I1R B;  4DKD A;  3N0P A;  5D28 B;  1M48 A;  1ITM A;  4YPG C;  2GMF A;  2O6I A;  2CFP A;  3NCC A;  5KNH I;  4FA8 E;  1ETE A;  3HOY D;  1FG9 A;  1QVN A;  1HWG A;  2B8U A;  4NN7 A;  3G9V B;  3AYH A;  4PS4 A;  5EQH A;  2XQB A;  3DI3 A;  1HIK A;  3L5X A;  1PY2 A;  4A3G D;  5LQB A;  5FLM D;  2JA7 D;  4WRL B;  1N1F A;  1HZI A;  4GS7 A;  4BY1 D;  1B5L A;  1LK3 A;  1RCB A;  4OAA A;  1PW6 A;  1BUY A;  1D9G A;  1CYL A;  5IP9 D;  1EVS A;  3HOV D;  4YB9 D;  1Y14 A;  2OQP A;  5FUC A;  1Y6N L;  2LAG A;  2JA5 D;  1Y6M L;  1ALU A;  4GBY A;  4YUE C;  1GNC A;  3Q1S I;  2JA6 D;  2Q7N B;  5D70 A;  3HOX D;  4LRL A;  4DKC A;  1YKB A;  1Z7C A;  3PO2 D;  3DUH C;  1HUW A;  3QB7 A;  4J05 A;  4JRE A;  3H3V E;  2V8N A;  4DOH A;  4TPG A;  3TGX B;  5EQI A;  1A22 A;  4BY7 D;  4A93 D;  2B8Z A;  5GXB A;  4J4L C;  1ITL A;  4TPH A;  1M4C A;  1NBP A;  4O9H A;  4IU8 A;  4A3D D;  2Q14 A;  4JA3 A;  3EJJ A;  2R7Z D; 
#chains in the Genus database with same CATH homology
 4GC0 A;  4U4T A;  4ZYR A;  4TPG A;  4PYP A;  5A2O A;  4GBZ A;  4YB9 D;  5EQI A;  4XNJ A;  4W6V A;  3WDO A;  2Y5Y A;  4IKV A;  4TPJ A;  4JA3 A;  4IU9 A;  4YBQ A;  4U4V A;  5D59 A;  2XUT A;  4D2D A;  5GXB A;  2CFP A;  4IKZ A;  4IKY A;  4LEP A;  4LDS A;  2CFQ A;  4U4W A;  4Q65 A;  4D2C A;  5D58 A;  5C65 A;  4TPH A;  4XNI A;  5D6K A;  4D2B A;  4J05 A;  4JR9 A;  4JRE A;  1PW4 A;  3O7P A;  1PV6 A;  4IKX A;  4QIQ A;  5A2N A;  4GBY A;  4UVM A;  4ZWB A;  4IU8 A;  2V8N A;  4OH3 A;  4IKW A;  5EQG A;  4OAA A;  5EQH A;  4ZW9 A;  3O7Q A;  4ZWC A;  4APS A;  1PV7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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